JP2012509886A5 - - Google Patents
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- Publication number
- JP2012509886A5 JP2012509886A5 JP2011537606A JP2011537606A JP2012509886A5 JP 2012509886 A5 JP2012509886 A5 JP 2012509886A5 JP 2011537606 A JP2011537606 A JP 2011537606A JP 2011537606 A JP2011537606 A JP 2011537606A JP 2012509886 A5 JP2012509886 A5 JP 2012509886A5
- Authority
- JP
- Japan
- Prior art keywords
- tcl1
- activator protein
- promotes
- pharmaceutical composition
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11678608P | 2008-11-21 | 2008-11-21 | |
| US61/116,786 | 2008-11-21 | ||
| PCT/US2009/065072 WO2010059779A1 (en) | 2008-11-21 | 2009-11-19 | Tcl1 AS A TRANSCRIPTIONAL REGULATOR |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012509886A JP2012509886A (ja) | 2012-04-26 |
| JP2012509886A5 true JP2012509886A5 (cg-RX-API-DMAC10.html) | 2012-06-07 |
Family
ID=42198493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011537606A Pending JP2012509886A (ja) | 2008-11-21 | 2009-11-19 | 転写制御因子としてのＴｃｌ１ |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20110311555A1 (cg-RX-API-DMAC10.html) |
| EP (1) | EP2352524A1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP2012509886A (cg-RX-API-DMAC10.html) |
| CN (1) | CN102271706A (cg-RX-API-DMAC10.html) |
| AU (1) | AU2009316584A1 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2744326A1 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2010059779A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007016548A2 (en) | 2005-08-01 | 2007-02-08 | The Ohio State University Research Foundation | Micro-rna-based methods and compositions for the diagnosis, prognosis and treatment of breast cancer |
| US8481505B2 (en) | 2005-09-12 | 2013-07-09 | The Ohio State University Research Foundation | Compositions and methods for the diagnosis and therapy of BCL2-associated cancers |
| WO2007081680A2 (en) | 2006-01-05 | 2007-07-19 | The Ohio State University Research Foundation | Microrna expression abnormalities in pancreatic endocrine and acinar tumors |
| AU2007205234B2 (en) | 2006-01-05 | 2012-07-12 | The Ohio State University Research Foundation | MicroRNA-based methods and compositions for the diagnosis, prognosis and treatment of lung cancer |
| EP2484782B1 (en) | 2006-01-05 | 2015-11-18 | The Ohio State University Research Foundation | MicroRNA-based methods and compositions for the diagnosis and treatment of solid cancers |
| ES2446362T3 (es) | 2006-03-20 | 2014-03-07 | The Ohio State University Research Foundation | Huellas de microARN durante megacariocipoyesis humana |
| ES2425387T3 (es) | 2006-07-13 | 2013-10-15 | The Ohio State University Research Foundation | Mir-106a para diagnosticar adenocarcinoma de colon de pronóstico de supervivencia pobre |
| US8071292B2 (en) | 2006-09-19 | 2011-12-06 | The Ohio State University Research Foundation | Leukemia diagnostic methods |
| WO2008054828A2 (en) | 2006-11-01 | 2008-05-08 | The Ohio State University Research Foundation | Microrna expression signature for predicting survival and metastases in hepatocellular carcinoma |
| JP2010516291A (ja) | 2007-01-31 | 2010-05-20 | ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション | 急性骨髄性白血病（ａｍｌ）の診断、予後及び治療のためのマイクロｒｎａに基づく方法及び組成物 |
| US8465917B2 (en) | 2007-06-08 | 2013-06-18 | The Ohio State University Research Foundation | Methods for determining heptocellular carcinoma subtype and detecting hepatic cancer stem cells |
| US8053186B2 (en) | 2007-06-15 | 2011-11-08 | The Ohio State University Research Foundation | Oncogenic ALL-1 fusion proteins for targeting Drosha-mediated microRNA processing |
| EP2173911B1 (en) | 2007-07-31 | 2014-06-18 | The Ohio State University Research Foundation | Methods for reverting methylation by targeting dnmt3a and dnmt3b |
| EP2653561B1 (en) | 2007-08-03 | 2016-03-02 | The Ohio State University Research Foundation | Ultraconserved regions encoding ncRNAs |
| EP3028708A1 (en) | 2007-08-22 | 2016-06-08 | The Ohio State University Research Foundation | Methods and compositions for inducing deregulation of epha7 and erk phosphorylation in human acute leukemias |
| WO2009055773A2 (en) | 2007-10-26 | 2009-04-30 | The Ohio State University Research Foundation | Methods for identifying fragile histidine triad (fhit) interaction and uses thereof |
| WO2009152300A1 (en) | 2008-06-11 | 2009-12-17 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Use of mir-26 family as a predictive marker of hepatocellular carcinoma and responsiveness to therapy |
| EP2504452A4 (en) | 2009-11-23 | 2014-06-11 | Univ Ohio State Res Found | MATERIALS AND METHODS FOR INFLUENCING GROWTH, MIGRATION AND INVASION OF TUMOR CELLS |
| WO2012065049A1 (en) | 2010-11-12 | 2012-05-18 | The Ohio State University Research Foundation | Materials and methods related to microrna-21, mismatch repair, and colorectal cancer |
| CA2817982C (en) | 2010-11-15 | 2020-06-30 | The Regents Of The University Of Michigan | Controlled release mucoadhesive systems |
| JP2014509852A (ja) | 2011-03-07 | 2014-04-24 | ジ・オハイオ・ステート・ユニバーシティ | マイクロＲＮＡ−１５５（ｍｉＲ−１５５）により誘導される変異誘発活性は炎症および癌を結び付ける |
| CA2852066A1 (en) | 2011-10-14 | 2013-04-18 | The Ohio State University | Methods and materials related to ovarian cancer |
| EP2790735A4 (en) | 2011-12-13 | 2015-12-09 | Ohio State Innovation Foundation | METHODS AND COMPOSITIONS RELATING TO MIR-21 AND MIR-29A, EXOSOME INHIBITION, AND CANCER METASTASIS |
| JP2015511121A (ja) | 2012-01-20 | 2015-04-16 | ジ・オハイオ・ステート・ユニバーシティ | 浸潤性および予後に関する乳がんバイオマーカーシグネチャー |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5985598A (en) * | 1994-10-27 | 1999-11-16 | Thomas Jefferson University | TCL-1 gene and protein and related methods and compositions |
| US20010026796A1 (en) * | 2000-03-14 | 2001-10-04 | Croce Carlo M. | TCL1 enhances Akt kinase activity and mediates its nuclear translocation |
| GB0128898D0 (en) * | 2001-12-03 | 2002-01-23 | Biotech Res Ventures Pte Ltd | Materials and methods relating to the stabilization and activation of a tumour suppressor protein |
| CA2478065C (en) * | 2002-03-08 | 2013-01-08 | Eisai Co. Ltd. | Macrocyclic compounds useful as pharmaceuticals |
-
2009
- 2009-11-19 AU AU2009316584A patent/AU2009316584A1/en not_active Abandoned
- 2009-11-19 CN CN2009801530248A patent/CN102271706A/zh active Pending
- 2009-11-19 WO PCT/US2009/065072 patent/WO2010059779A1/en not_active Ceased
- 2009-11-19 CA CA2744326A patent/CA2744326A1/en not_active Abandoned
- 2009-11-19 EP EP09828195A patent/EP2352524A1/en not_active Withdrawn
- 2009-11-19 US US13/129,881 patent/US20110311555A1/en not_active Abandoned
- 2009-11-19 JP JP2011537606A patent/JP2012509886A/ja active Pending
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