JP2012509666A5 - - Google Patents
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- JP2012509666A5 JP2012509666A5 JP2011537633A JP2011537633A JP2012509666A5 JP 2012509666 A5 JP2012509666 A5 JP 2012509666A5 JP 2011537633 A JP2011537633 A JP 2011537633A JP 2011537633 A JP2011537633 A JP 2011537633A JP 2012509666 A5 JP2012509666 A5 JP 2012509666A5
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- JP
- Japan
- Prior art keywords
- cells
- cell
- hspc
- population
- support
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19993208P | 2008-11-21 | 2008-11-21 | |
| US61/199,932 | 2008-11-21 | ||
| PCT/US2009/065217 WO2010059876A2 (en) | 2008-11-21 | 2009-11-19 | In vitro human b lymphopoiesis culture system |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012509666A JP2012509666A (ja) | 2012-04-26 |
| JP2012509666A5 true JP2012509666A5 (enExample) | 2013-01-10 |
| JP5726744B2 JP5726744B2 (ja) | 2015-06-03 |
Family
ID=42198808
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011537633A Active JP5726744B2 (ja) | 2008-11-21 | 2009-11-19 | 生体外におけるヒトｂリンパ球産生培養システム |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US8133727B2 (enExample) |
| EP (1) | EP2358868B1 (enExample) |
| JP (1) | JP5726744B2 (enExample) |
| WO (1) | WO2010059876A2 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2786664C (en) | 2010-01-08 | 2020-03-10 | Immusoft Corporation | Vectors and methods for transducing b cells |
| RU2737765C2 (ru) * | 2012-05-04 | 2020-12-02 | Пфайзер Инк. | Простатоассоциированные антигены и иммунотерапевтические схемы на основе вакцин |
| AU2013344992A1 (en) * | 2012-11-13 | 2015-05-14 | Genentech, Inc. | Enrichment of antigen-specific plasmablasts |
| JP6392315B2 (ja) | 2013-03-14 | 2018-09-19 | イミュソフト コーポレーション | インビトロでのメモリーｂ細胞分化方法およびｖｓｖ−ｇ偽型ウイルスベクターを用いる形質導入方法 |
| EP4177336A1 (en) | 2014-12-19 | 2023-05-10 | Immusoft Corporation | B cells for in vivo delivery of therapeutic agents |
| WO2016161446A1 (en) * | 2015-04-03 | 2016-10-06 | Dana-Farber Cancer Institute, Inc. | Composition and methods of genome editing of b-cells |
| JP7215994B2 (ja) | 2016-09-06 | 2023-01-31 | ザ チルドレンズ メディカル センター コーポレーション | 人工多能性幹細胞由来の免疫細胞 |
| AU2017367695A1 (en) | 2016-12-02 | 2019-06-13 | Juno Therapeutics, Inc. | Engineered B cells and related compositions and methods |
| CN111936617A (zh) | 2018-03-16 | 2020-11-13 | 益缪索夫特公司 | 经遗传工程化以分泌卵泡抑素的b细胞以及使用所述b细胞来治疗卵泡抑素相关的疾病、病况、病症及增强肌肉生长和力量的方法 |
| CN109234232A (zh) * | 2018-09-30 | 2019-01-18 | 杭州华安单抗生物技术有限公司 | 兔外周血b细胞的培养体系及培养方法、抗体的制备方法和应用 |
| CN117413052A (zh) * | 2021-04-30 | 2024-01-16 | 加拿大干细胞技术公司 | 用于分化和扩增b谱系细胞的组合物和方法 |
| US20250152714A1 (en) | 2023-11-15 | 2025-05-15 | Immusoft Corporation | Migratory modified differentiated b cells for cancer therapy |
| WO2025147573A2 (en) | 2024-01-05 | 2025-07-10 | Immusoft Corporation | Glp-1 expressing modified b cells for the treatment of metabolic disease |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7939059B2 (en) * | 2001-12-10 | 2011-05-10 | California Institute Of Technology | Method for the generation of antigen-specific lymphocytes |
| IL162111A0 (en) * | 2001-12-22 | 2005-11-20 | 4Antibody Ag | Method for the generation of generically modified vertebrate precursor lymphocytes and use thereof for the production of heterologo |
| US20100323401A1 (en) * | 2006-05-11 | 2010-12-23 | Lewis George K | General method for generating human antibody responses in vitro |
-
2009
- 2009-11-19 EP EP09828251.0A patent/EP2358868B1/en active Active
- 2009-11-19 WO PCT/US2009/065217 patent/WO2010059876A2/en not_active Ceased
- 2009-11-19 US US12/622,379 patent/US8133727B2/en active Active
- 2009-11-19 JP JP2011537633A patent/JP5726744B2/ja active Active
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