JP2012509666A5 - - Google Patents

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Publication number
JP2012509666A5
JP2012509666A5 JP2011537633A JP2011537633A JP2012509666A5 JP 2012509666 A5 JP2012509666 A5 JP 2012509666A5 JP 2011537633 A JP2011537633 A JP 2011537633A JP 2011537633 A JP2011537633 A JP 2011537633A JP 2012509666 A5 JP2012509666 A5 JP 2012509666A5
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JP
Japan
Prior art keywords
cells
cell
hspc
population
support
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JP2011537633A
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English (en)
Japanese (ja)
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JP2012509666A (ja
JP5726744B2 (ja
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Priority claimed from PCT/US2009/065217 external-priority patent/WO2010059876A2/en
Publication of JP2012509666A publication Critical patent/JP2012509666A/ja
Publication of JP2012509666A5 publication Critical patent/JP2012509666A5/ja
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Publication of JP5726744B2 publication Critical patent/JP5726744B2/ja
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JP2011537633A 2008-11-21 2009-11-19 生体外におけるヒトｂリンパ球産生培養システム Active JP5726744B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19993208P 2008-11-21 2008-11-21
US61/199,932 2008-11-21
PCT/US2009/065217 WO2010059876A2 (en) 2008-11-21 2009-11-19 In vitro human b lymphopoiesis culture system

Publications (3)

Publication Number Publication Date
JP2012509666A JP2012509666A (ja) 2012-04-26
JP2012509666A5 true JP2012509666A5 (enExample) 2013-01-10
JP5726744B2 JP5726744B2 (ja) 2015-06-03

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ID=42198808

Family Applications (1)

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JP2011537633A Active JP5726744B2 (ja) 2008-11-21 2009-11-19 生体外におけるヒトｂリンパ球産生培養システム

Country Status (4)

Country Link
US (1) US8133727B2 (enExample)
EP (1) EP2358868B1 (enExample)
JP (1) JP5726744B2 (enExample)
WO (1) WO2010059876A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2521789T3 (en) 2010-01-08 2017-03-27 Immusoft Corp VECTORS AND PROCEDURE FOR B-CELL TRANSDUCTION
PL2844282T3 (pl) * 2012-05-04 2019-11-29 Pfizer Antygeny związane z gruczołem krokowym i schematy immunoterapii oparte na szczepionce
BR112015009933A2 (pt) * 2012-11-13 2017-12-12 Genentech Inc métodos de obtenção de uma população de plasmablastos, de enriquecimento de plasmablastos e de identificação de plasmablasto
ES2786253T3 (es) * 2013-03-14 2020-10-09 Immusoft Corp Métodos para la diferenciación y transducción in vitro de células b de memoria con vectores virales pseudotipados vsv-g
EP4177336A1 (en) 2014-12-19 2023-05-10 Immusoft Corporation B cells for in vivo delivery of therapeutic agents
CA2981077A1 (en) * 2015-04-03 2016-10-06 Dana-Farber Cancer Institute, Inc. Composition and methods of genome editing of b-cells
JP7215994B2 (ja) 2016-09-06 2023-01-31 ザ チルドレンズ メディカル センター コーポレーション 人工多能性幹細胞由来の免疫細胞
WO2018102612A1 (en) 2016-12-02 2018-06-07 Juno Therapeutics, Inc. Engineered b cells and related compositions and methods
CA3093716A1 (en) 2018-03-16 2019-09-19 Immusoft Corporation B cells genetically engineered to secrete follistatin and methods of using the same to treat follistatin-related diseases, conditions, disorders and to enhance muscle growth and strength
CN109234232A (zh) * 2018-09-30 2019-01-18 杭州华安单抗生物技术有限公司 兔外周血b细胞的培养体系及培养方法、抗体的制备方法和应用
WO2022226659A1 (en) * 2021-04-30 2022-11-03 Stemcell Technologies Canada Inc. Compositions and methods for differentiating and expanding b lineage cells
US20250152714A1 (en) 2023-11-15 2025-05-15 Immusoft Corporation Migratory modified differentiated b cells for cancer therapy
WO2025147573A2 (en) 2024-01-05 2025-07-10 Immusoft Corporation Glp-1 expressing modified b cells for the treatment of metabolic disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7939059B2 (en) 2001-12-10 2011-05-10 California Institute Of Technology Method for the generation of antigen-specific lymphocytes
WO2003068819A1 (en) * 2001-12-22 2003-08-21 4-Antibody Ag Method for the generation of genetically modified vertebrate precursor lymphocytes and use thereof for the production of heterologous binding proteins
EP2021460A4 (en) * 2006-05-11 2010-11-17 Univ Maryland Biotech Inst GENERAL METHOD FOR GENERATING IN VITRO HUMAN ANTIBODY RESPONSES

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