JP2012505928A5 - - Google Patents
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- Publication number
- JP2012505928A5 JP2012505928A5 JP2011533097A JP2011533097A JP2012505928A5 JP 2012505928 A5 JP2012505928 A5 JP 2012505928A5 JP 2011533097 A JP2011533097 A JP 2011533097A JP 2011533097 A JP2011533097 A JP 2011533097A JP 2012505928 A5 JP2012505928 A5 JP 2012505928A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- composition according
- general formula
- formula
- ocular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 15
- 208000007135 Retinal Neovascularization Diseases 0.000 claims 4
- 208000022873 Ocular disease Diseases 0.000 claims 3
- 239000004480 active ingredient Substances 0.000 claims 3
- SQVRNKJHWKZAKO-UHFFFAOYSA-N beta-N-Acetyl-D-neuraminic acid Natural products CC(=O)NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO SQVRNKJHWKZAKO-UHFFFAOYSA-N 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- 208000030533 eye disease Diseases 0.000 claims 3
- 150000002772 monosaccharides Chemical group 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- SQVRNKJHWKZAKO-OQPLDHBCSA-N sialic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)OC1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-OQPLDHBCSA-N 0.000 claims 3
- 239000012453 solvate Substances 0.000 claims 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 2
- 229930182830 galactose Natural products 0.000 claims 2
- 239000008103 glucose Substances 0.000 claims 2
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 claims 2
- 230000002757 inflammatory effect Effects 0.000 claims 2
- 239000000843 powder Substances 0.000 claims 2
- 208000005494 xerophthalmia Diseases 0.000 claims 2
- BJHCYTJNPVGSBZ-YXSASFKJSA-N 1-[4-[6-amino-5-[(Z)-methoxyiminomethyl]pyrimidin-4-yl]oxy-2-chlorophenyl]-3-ethylurea Chemical compound CCNC(=O)Nc1ccc(Oc2ncnc(N)c2\C=N/OC)cc1Cl BJHCYTJNPVGSBZ-YXSASFKJSA-N 0.000 claims 1
- 206010010741 Conjunctivitis Diseases 0.000 claims 1
- 206010012689 Diabetic retinopathy Diseases 0.000 claims 1
- 206010016654 Fibrosis Diseases 0.000 claims 1
- 208000010412 Glaucoma Diseases 0.000 claims 1
- 206010021143 Hypoxia Diseases 0.000 claims 1
- 206010065630 Iris neovascularisation Diseases 0.000 claims 1
- 206010065062 Meibomian gland dysfunction Diseases 0.000 claims 1
- 206010038933 Retinopathy of prematurity Diseases 0.000 claims 1
- 208000021386 Sjogren Syndrome Diseases 0.000 claims 1
- 206010042033 Stevens-Johnson syndrome Diseases 0.000 claims 1
- 231100000168 Stevens-Johnson syndrome Toxicity 0.000 claims 1
- 206010052779 Transplant rejections Diseases 0.000 claims 1
- 206010046851 Uveitis Diseases 0.000 claims 1
- 102000016549 Vascular Endothelial Growth Factor Receptor-2 Human genes 0.000 claims 1
- 108010053099 Vascular Endothelial Growth Factor Receptor-2 Proteins 0.000 claims 1
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 claims 1
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 239000000607 artificial tear Substances 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 238000004140 cleaning Methods 0.000 claims 1
- 239000003405 delayed action preparation Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 210000002889 endothelial cell Anatomy 0.000 claims 1
- 239000003889 eye drop Substances 0.000 claims 1
- 208000024519 eye neoplasm Diseases 0.000 claims 1
- 230000004761 fibrosis Effects 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 235000013376 functional food Nutrition 0.000 claims 1
- 239000008187 granular material Substances 0.000 claims 1
- 230000007954 hypoxia Effects 0.000 claims 1
- 201000001371 inclusion conjunctivitis Diseases 0.000 claims 1
- 206010023332 keratitis Diseases 0.000 claims 1
- 210000004561 lacrimal apparatus Anatomy 0.000 claims 1
- 239000002502 liposome Substances 0.000 claims 1
- 239000000314 lubricant Substances 0.000 claims 1
- 230000001050 lubricating effect Effects 0.000 claims 1
- 208000002780 macular degeneration Diseases 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 201000008106 ocular cancer Diseases 0.000 claims 1
- 238000004806 packaging method and process Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000002207 retinal effect Effects 0.000 claims 1
- 230000028327 secretion Effects 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 239000006188 syrup Substances 0.000 claims 1
- 235000020357 syrup Nutrition 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- 206010044325 trachoma Diseases 0.000 claims 1
- 230000002792 vascular Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020080102660A KR101116868B1 (ko) | 2008-10-20 | 2008-10-20 | 안질환의 예방 또는 치료용 조성물 |
| KR10-2008-0102660 | 2008-10-20 | ||
| PCT/KR2009/005983 WO2010047500A2 (ko) | 2008-10-20 | 2009-10-16 | 안질환의 예방 또는 치료용 조성물 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012505928A JP2012505928A (ja) | 2012-03-08 |
| JP2012505928A5 true JP2012505928A5 (enExample) | 2012-12-06 |
| JP5611216B2 JP5611216B2 (ja) | 2014-10-22 |
Family
ID=42119814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011533097A Active JP5611216B2 (ja) | 2008-10-20 | 2009-10-16 | 眼疾患の予防又は治療用組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8524686B2 (enExample) |
| EP (1) | EP2361627B1 (enExample) |
| JP (1) | JP5611216B2 (enExample) |
| KR (1) | KR101116868B1 (enExample) |
| DK (1) | DK2361627T3 (enExample) |
| ES (1) | ES2472440T3 (enExample) |
| WO (1) | WO2010047500A2 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101438744B1 (ko) * | 2012-08-02 | 2014-09-15 | 전남대학교산학협력단 | 아디포넥틴을 유효성분으로 포함하는 안구건조증 또는 염증성 안구표면 질환의 예방 또는 치료용 조성물 |
| US10330670B2 (en) | 2012-10-24 | 2019-06-25 | National University Corporation Tokyo University Of Agriculture And Technology | Therapeutic or prophylactic agent for retinopathy of prematurity, testing method for retinopathy of prematurity, and screening method for therapeutic or prophylactic substance for retinopathy of prematurity |
| WO2018171850A1 (en) * | 2017-03-23 | 2018-09-27 | Københavns Universitet | Prebiotic compounds or compositions for use in treatment of sjögren's syndrome |
| KR102495473B1 (ko) | 2020-10-06 | 2023-02-06 | 서울대학교병원 | 앰피레귤린을 유효성분으로 포함하는 안질환 치료용 조성물 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5260280A (en) * | 1989-02-07 | 1993-11-09 | Snow Brand Milk Products Co., Ltd. | Bacterial toxin neutralizer |
| EP0546728A3 (en) | 1991-12-13 | 1993-09-08 | Alcon Laboratories Inc | Physiological tear compositions and methods for their preparation |
| IT1271624B (it) * | 1994-03-21 | 1997-06-04 | Lifegroup Spa | Derivati glucosidici di n-acil alchilamine capaci di esercitare effetto o neuroprotettivo utilizzabili nelle patologie acute e croniche del sistema nervoso centrale correlate ad eccitotossicita' |
| JP4082746B2 (ja) * | 1995-03-20 | 2008-04-30 | 雪印乳業株式会社 | シアリルラクトースの分離方法 |
| US5736533A (en) * | 1995-06-07 | 1998-04-07 | Neose Technologies, Inc. | Bacterial inhibition with an oligosaccharide compound |
| JPH0967270A (ja) * | 1995-08-31 | 1997-03-11 | Res Dev Corp Of Japan | 水晶体混濁の予防および治療法、並びにそのための薬 剤 |
| AU7277798A (en) * | 1997-05-01 | 1998-11-24 | Cytel Corporation | Use of sialyl galactosides and related compounds as anti-angiogenic agents |
| US6239088B1 (en) * | 1999-03-19 | 2001-05-29 | Color Access, Inc. | Nonirritating cleansing composition |
| SE9904289D0 (sv) * | 1999-11-26 | 1999-11-26 | Niklas Arnberg | Method and camposition for the treatment of adenovairal ocular infections |
| US20070286896A1 (en) * | 2003-08-01 | 2007-12-13 | National Institute Of Advanced Industrial Science And Technology | Therapeutic or Diagnostic Drug for Inflammatory Disease Comprising Targeting Liposome |
| CA2548140A1 (en) * | 2003-12-05 | 2005-06-23 | University Of Massachusetts | Oligosaccharide compositions and use thereof in the treatment of infection |
| WO2007047489A2 (en) * | 2005-10-18 | 2007-04-26 | Acadia Pharmaceuticals Inc. | Compositions and methods for use in cancer therapy |
-
2008
- 2008-10-20 KR KR1020080102660A patent/KR101116868B1/ko active Active
-
2009
- 2009-10-16 ES ES09822176.5T patent/ES2472440T3/es active Active
- 2009-10-16 US US13/124,965 patent/US8524686B2/en active Active
- 2009-10-16 EP EP09822176.5A patent/EP2361627B1/en active Active
- 2009-10-16 JP JP2011533097A patent/JP5611216B2/ja active Active
- 2009-10-16 DK DK09822176.5T patent/DK2361627T3/da active
- 2009-10-16 WO PCT/KR2009/005983 patent/WO2010047500A2/ko not_active Ceased
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