JP2012010966A - Adhesive sheet for peeling horny layer - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an adhesive sheet for peeling a horny layer, which has an excellent horny layer peeling ability for fine peeling without leaving glue to the skin and has a large horny layer peeling amount.SOLUTION: The adhesive sheet for peeling the horny layer includes a support and an adhesive layer formed on the support. Of the adhesive layer, a storage modulus at 32°C is 2.0×10to 5.0×10Pa, and a storage modulus at 0°C is 1.6×10to 4.0×10Pa.

Description

  The present invention relates to a pressure-sensitive adhesive sheet for exfoliating exfoliation having a support and a pressure-sensitive adhesive layer formed on the support and having excellent exfoliation ability.

The stratum corneum in the outermost layer of the skin is an interface that separates the inside of the living body from the outside world, and has a barrier function that prevents biological components from leaking into the outside world and prevents harmful components from entering the living body.
As described above, the keratin has an important function for a living body. For example, an active ingredient such as a drug or a vaccine is administered from the epidermis into the living body (percutaneous absorption), or a suction leachate for the purpose of clinical examination or the like. It may be necessary to remove the stratum corneum, for example, when vacuuming the skin from the skin.

Conventionally, as a method for removing the keratin, for example, a method of removing the keratin by sticking an adhesive tape (adhesive sheet for exfoliating keratin) on the skin surface and peeling it after a certain time is known (Patent Document) 1-6 etc.).
However, the conventional keratin exfoliation adhesive sheet has a small amount of exfoliation that can be exfoliated by a single exfoliation, and it is necessary to repeatedly exfoliate with a plurality of exfoliation exfoliation sheets. there were. Therefore, the present situation is that development of a pressure-sensitive adhesive sheet for exfoliating exfoliation having more excellent exfoliating ability is required.

JP-A-5-123326 JP-A-3-151951 JP 2007-289672 A JP 2008-201698 A JP 2009-102304 A JP 2009-29742 A

  This invention is made | formed in view of an above-described situation, The subject is providing the adhesive sheet for exfoliation which is excellent in exfoliation ability.

  As a result of intensive studies to solve the above problems, the inventors of the present invention are horny exfoliation pressure-sensitive adhesive sheets having a support and a pressure-sensitive adhesive layer formed on the support, It has been found that a keratin exfoliation pressure-sensitive adhesive sheet having a storage elastic modulus at 32 ° C. and a storage elastic modulus at 0 ° C. in a specific range is extremely excellent in exfoliating ability, and has completed the present invention.

Thus, according to the present invention, the following pressure-sensitive adhesive sheet for exfoliating (1) to (6) is provided.
(1) A stratum corneum peeling pressure-sensitive adhesive sheet having a support and a pressure-sensitive adhesive layer formed on the support, and the storage elastic modulus at 32 ° C. of the pressure-sensitive adhesive layer is 2.0 × 10 ^{5 to} 5. .0 × a ¹⁰ 5 Pa, the pressure-sensitive adhesive sheet for desquamating, wherein the storage modulus at 0 ℃ is ^{1.6 × 10 6 ~4.0 × 10 8} Pa.

(2) The stratum corneum according to (1), wherein the pressure-sensitive adhesive layer is formed from a pressure-sensitive adhesive composition containing an acrylic polymer and a rosin resin having a softening point of 80 to 160 ° C. by a ring and ball method. Peeling adhesive sheet.
(3) The acrylic polymer has a salt structure in the (meth) acrylic acid alkyl ester having a C 6-12 alkyl group, a monomer having a carboxyl group, a monomer having a hydroxyl group, and a side chain. The pressure-sensitive adhesive sheet for exfoliation according to (2), which is obtained by copolymerizing a monomer composition containing at least one monomer selected from the group consisting of monomers having no nitrogen atom.

(4) The pressure-sensitive adhesive sheet for exfoliation according to (3), wherein the monomer composition further contains a monomer having a plurality of polymerizable unsaturated groups in the molecule.
(5) The pressure-sensitive adhesive sheet for exfoliation according to (2), wherein the rosin resin has a number average molecular weight of 300 to 2,000.
(6) The pressure-sensitive adhesive sheet for exfoliation according to (2), wherein the rosin resin is used in an amount of 10 to 40 parts by mass with respect to 100 parts by mass of the acrylic polymer.

  The pressure-sensitive adhesive sheet for exfoliation of the present invention has no adhesive residue on the skin and can be exfoliated cleanly, has a large amount of exfoliation and has extremely excellent exfoliation ability.

Hereinafter, the present invention will be described in detail.
The pressure-sensitive adhesive sheet for exfoliation of the present invention is a pressure-sensitive adhesive sheet for exfoliation having a support and a pressure-sensitive adhesive layer formed on the support, and the storage elastic modulus of the pressure-sensitive adhesive layer at 32 ° C. 2.0 × a ¹⁰ 5 ^~5.0 × ¹⁰ 5 Pa, and wherein the storage modulus at 0 ℃ is ^{1.6 × 10 6 ~4.0 × 10 8} Pa.

(Support)
The support used for the exfoliated pressure-sensitive adhesive sheet of the present invention is not particularly limited as long as it can support the pressure-sensitive adhesive layer.
Supports used include polyester films such as polyethylene terephthalate (PET), polyethylene, polypropylene, ethylene / methacrylic acid copolymers, polyolefin films such as ethylene / methyl methacrylate, polyurethane films, and polystyrene-based thermoplastic elastomers. Resin films such as films; Films obtained by vapor-depositing metals such as aluminum on these resin films; Fibers such as woven fabrics, knitted fabrics and nonwoven fabrics made of various synthetic fibers and / or natural fibers; fine paper, glassine paper, Papers such as coated paper; laminates thereof; and the like.

  The thickness of the support is not particularly limited, but when the support is a resin film, it is usually 5 to 250 μm, preferably 10 to 100 μm, and when the support is made of fibers or papers, Usually, it is 10-1000 micrometers, Preferably it is 20-500 micrometers.

  In addition, surface treatment such as primer treatment, corona treatment, plasma treatment or the like may be performed in advance on the surface of the support on the side where the pressure-sensitive adhesive layer is formed in order to enhance the adhesion with the pressure-sensitive adhesive layer. In addition, in the case where the obtained exfoliated pressure-sensitive adhesive sheet is a wound body suitable for transportation and storage, the surface of the support on which the pressure-sensitive adhesive layer is not formed is coated with a silicone-based release agent or a long-chain alkyl compound. The peeling treatment may be performed by such as.

(Adhesive layer)
The pressure-sensitive adhesive layer used in the pressure-sensitive adhesive sheet for exfoliation of the present invention has a storage elastic modulus at 32 ° C. of 2.0 × 10 ^{5 to} 5.0 × 10 ⁵ Pa and a storage elastic modulus at 0 ° C. of 1.6 ×. 10 ^{6 to} 4.0 × 10 ⁸ Pa.
The storage elastic modulus is an index representing the rigidity of the viscoelastic material and can be measured by a conventionally known viscoelasticity measuring device.

  Since the pressure-sensitive adhesive sheet for exfoliation of the present invention uses the pressure-sensitive adhesive layer having the above storage elastic modulus, it has excellent exfoliation performance. In particular, when exfoliating, the exfoliating ability more excellent is exhibited by exfoliating from the skin at a exfoliation speed of 1 m / min or more.

More specifically, by setting the storage elastic modulus of the pressure-sensitive adhesive layer at 32 ° C. to 2.0 × 10 ^{5 to} 5.0 × 10 ⁵ Pa, the unevenness of the skin when the adhesive sheet for exfoliating exfoliation is applied is used. The followability can be made particularly excellent.
Moreover, by setting the storage elastic modulus of the pressure-sensitive adhesive layer at 0 ° C. to 1.6 × 10 ^{6 to} 4.0 × 10 ⁸ Pa, the pressure-sensitive adhesive sheet for exfoliating the horny layer is peeled from the skin at a peeling speed of 1 m / min or more. In doing so, no adhesive residue on the skin can be produced.

  The method for obtaining a pressure-sensitive adhesive layer having a storage elastic modulus in the above range is not particularly limited. Especially, the method of forming an adhesive layer using the adhesive composition containing an acrylic polymer and the rosin-type resin whose softening point by a ring and ball method is 80-160 degreeC is preferable. The pressure-sensitive adhesive layer can be easily formed by applying such a pressure-sensitive adhesive composition on a support and drying the resulting coating film.

(Acrylic polymer)
Although it does not specifically limit as an acryl-type polymer to be used, From the viewpoint from which the adhesive layer which has the said storage elastic modulus is obtained easily, the (meth) acrylic-acid alkylester which has a C6-C12 alkyl group, and carboxyl At least one monomer selected from the group consisting of a monomer having a group, a monomer having a hydroxyl group, and a monomer having a nitrogen atom having no salt structure in the side chain (hereinafter referred to as “monomer having a carboxyl group”). That is obtained by copolymerizing a monomer composition containing Here, “(meth) acrylic acid” means “acrylic acid” or “methacrylic acid” (the same applies hereinafter).

  Examples of (meth) acrylic acid alkyl ester having an alkyl group having 6 to 12 carbon atoms (hereinafter sometimes simply referred to as “(meth) acrylic acid alkyl ester”) include (meth) acrylic acid n-hexyl, (meta ) -2-ethylhexyl acrylate, n-octyl (meth) acrylate, isooctyl (meth) acrylate, n-nonyl (meth) acrylate, isononyl (meth) acrylate, n-decyl (meth) acrylate, Examples thereof include n-dodecyl (meth) acrylate, cyclohexyl (meth) acrylate, and lauryl (meth) acrylate.

  The proportion of the (meth) acrylic acid alkyl ester used in the monomer composition is preferably 70 mol% or more, more preferably 80 to 99.99 mol%, more preferably 90 to 99, based on the entire monomer composition. More preferably, it is 9 mol%.

  Examples of the monomer having a carboxyl group include (meth) acrylic acid, β-carboxyethyl acrylate, itaconic acid, crotonic acid, maleic acid, fumaric acid, maleic anhydride and the like.

  As monomers having a hydroxyl group, (meth) acrylic acid hydroxyethyl ester, (meth) acrylic acid hydroxypropyl ester, (meth) acrylic acid hydroxybutyl ester, chloro-2-hydroxypropyl acrylate, diethylene glycol mono (meth) acrylate, Examples include allyl alcohol.

  Examples of monomers having a nitrogen atom having no salt structure in the side chain include acrylic monomers having amino groups such as aminoethyl (meth) acrylate; methylaminoethyl (meth) acrylate, dimethylaminoethyl (meth) acrylate , Acrylic monomers having a mono- or dialkylamino group having 1 to 4 carbon atoms, such as dimethylaminopropyl (meth) acrylate, dimethylaminobutyl (meth) acrylate; vinyl having a pyrrolidone ring such as N-vinyl-2-pyrrolidone System monomers; vinyl monomers having a pyridine ring such as 2-vinylpyridine and 4-vinylpyridine; vinyl monomers having an imidazole ring such as 1-vinylimidazole and 4-vinylimidazole; and the like.

  The use ratio of the monomer having a carboxyl group or the like in the monomer composition is not particularly limited, but is preferably less than 30 mol% and 0.01 to 20 mol% with respect to the entire monomer composition. Is more preferably 0.1 to 10 mol%.

  In the present invention, the monomer composition preferably further includes a monomer having a plurality of polymerizable unsaturated groups in the molecule in addition to the (meth) acrylic acid alkyl ester and the monomer having carboxyl.

  Examples of the monomer having a plurality of polymerizable unsaturated groups in the molecule include ethylene glycol di (meth) acrylate, diethylene glycol di (meth) acrylate, triethylene glycol di (meth) acrylate, polyethylene glycol di (meth) acrylate, Propylene glycol di (meth) acrylate, dipropylene glycol di (meth) acrylate, tripropylene glycol di (meth) acrylate, polypropylene glycol di (meth) acrylate, 1,3-butylene glycol di (meth) acrylate, 1,4- Butanediol di (meth) acrylate, 1,6-hexanediol di (meth) acrylate, 1,9-nonanediol di (meth) acrylate, neopentyl glycol di (meth) acrylate, trime Trimethylolpropane tri (meth) acrylate, tetramethylolmethane tri (meth) acrylate, such as glycerin methacrylate acrylate, di- or tri (meth) alkyl esters of polyols; divinylbenzene; and the like.

  When using a monomer having a plurality of polymerizable unsaturated groups in the molecule, the proportion of the monomer used is not particularly limited, but is preferably 0.001 to 0.1 mol% with respect to the entire monomer composition. , 0.01 to 0.05 mol% is more preferable.

The acrylic polymer can be obtained by copolymerizing the monomer composition by a conventionally known method.
The mass average molecular weight (Mw) of the obtained acrylic polymer is preferably 400,000 to 2,000,000, and preferably 600,000 to 1,600,000 from the viewpoint of obtaining a pressure-sensitive adhesive layer having a desired storage modulus. More preferred.
Here, the mass average molecular weight (Mw) is a value measured by gel permeation chromatography (GPC analysis) and converted to standard polystyrene (the same applies hereinafter).

(Rosin resin)
Examples of rosin resins having a softening point of 80 to 160 ° C. by ring-and-ball method (a kind of softening point measurement method) include natural resin rosin; modified rosin; rosin glycerol ester, rosin pentaerythritol ester, And hydrogenated rosin pentaerythritol esters and the like; and the like.
Among these, from the viewpoint of skin irritation resistance and aging resistance, hydrogenated rosin esters are preferable, and hydrogenated rosin glycerin esters are particularly preferable.

In the present invention, a rosin resin having a softening point of 80 to 160 ° C. by the ring and ball method (a kind of softening point measuring method) (hereinafter sometimes simply referred to as “rosin resin”) is used. It is more preferable to use a rosin resin having a softening point of 90 to 135 ° C. by the ring and ball method.
By using a rosin resin having such a softening point, it is possible to easily obtain a pressure-sensitive adhesive layer having a desired storage elastic modulus.

  The number average molecular weight of the rosin resin used is preferably 300 to 2000 from the viewpoint of obtaining a pressure-sensitive adhesive layer having a desired storage modulus.

  From the viewpoint of obtaining a pressure-sensitive adhesive layer having a desired storage elastic modulus, the rosin resin is preferably used in an amount of 10 to 40 parts by mass with respect to 100 parts by mass of the acrylic polymer.

  Other components may be added to the pressure-sensitive adhesive composition as long as the effects of the present invention are not impaired. Other components include curing agents, chemicals, humectants, antioxidants, viscosity modifiers, UV absorbers, masking agents, plasticizers, waxes, colorants, inorganic fillers, organic fillers, extenders, coupling agents, etc. And various additives.

(Preparation of adhesive composition)
The pressure-sensitive adhesive composition can be prepared by appropriately mixing and stirring the acrylic polymer, rosin resin, and optionally other components and an organic solvent according to a conventional method.

  Examples of the organic solvent used include aromatic hydrocarbon solvents such as toluene; ester solvents such as ethyl acetate and butyl acetate; ketone solvents such as acetone, methyl ethyl ketone, and methyl isobutyl ketone; n-pentane, n-hexane, and n- And aliphatic hydrocarbon solvents such as heptane; alicyclic hydrocarbon solvents such as cyclopentane and cyclohexane; and mixed solvents composed of two or more of these solvents.

  Although the usage-amount of an organic solvent is not specifically limited, It is 5-90 mass% normally with respect to the whole adhesive composition, Preferably it is 10-80 mass%, More preferably, it is 20-70 mass%.

(Formation of adhesive layer)
The method for forming the pressure-sensitive adhesive layer on the support is not particularly limited. For example, (i) a method of forming the pressure-sensitive adhesive layer by applying and drying the pressure-sensitive adhesive composition on the support, (ii) ) The pressure-sensitive adhesive composition is coated on a release sheet such as a polyethylene terephthalate (PET) film that has been subjected to a release treatment, dried to form a pressure-sensitive adhesive layer, and then supported on the formed pressure-sensitive adhesive layer. Examples include a method of laminating (bonding) a body and then peeling the release sheet.

  Application | coating of an adhesive composition can be performed using the existing coating device. Examples of the coating apparatus include a gravure coater, a Mayer bar coater, a roll coater, a knife coater, a die coater, and a screen coater.

  Although there is no restriction | limiting in particular in drying temperature, Usually, 60-200 degreeC, Preferably it is 80-120 degreeC. Although depending on the drying temperature, the drying time is usually 5 seconds to 10 minutes, preferably 10 seconds to 5 minutes.

  The average thickness of the obtained pressure-sensitive adhesive layer is not particularly limited, but is preferably 1 to 200 μm and more preferably 10 to 50 μm from the viewpoint of effectively exfoliating the stratum corneum.

(Release sheet)
A release sheet may be laminated on the obtained pressure-sensitive adhesive layer for storage and transportation.
Examples of release sheets include paper such as fine paper, glassine paper, coated paper, polyethylene laminated paper, and polypropylene laminated paper; polyester-based films such as PET, synthetic resin films such as polyolefin-based films such as polyethylene and polypropylene; and these And a paper or synthetic resin film having one or both surfaces subjected to a release treatment with a silicone release agent, a long-chain alkyl compound, or the like. Of these, a polyester film that has been subjected to a release treatment is preferred from the standpoint of availability and ease of handling.
The release sheet is peeled off when the keratin peeling adhesive sheet is used.

(Adhesive sheet for exfoliation)
The obtained pressure-sensitive adhesive sheet for exfoliation of the present invention is excellent in exfoliation ability. The superior exfoliation ability can be confirmed, for example, from the fact that the exfoliation amount is large and the adhesive residue is not seen on the skin.
Examples of the method for measuring the amount of exfoliation include the methods described in the following examples.

  Hereinafter, the present invention will be described in more detail with reference to Examples and Comparative Examples. However, this invention is not restrict | limited at all by these Examples.

Example 1
First, a monomer composed of 95 mol% of acrylic acid-2-ethylhexyl (2EHA), 4.97 mol% of N-vinyl-2-pyrrolidone (VP), and 0.03 mol% of 1,6-hexanediol diacrylate (HDDM) An ethyl acetate solution (solid content: 40% by mass) of acrylic polymer 1 obtained by copolymerizing composition 1 was prepared.
Here, as a rosin resin, a hydrogenated rosin glycerin ester resin having a softening point of 95 ° C. and a number average molecular weight of 580 (trade name “Pine Crystal KE-311” manufactured by Arakawa Chemical Industries, Ltd., hereinafter “rosin resin A”) 15.0 parts by mass with respect to 100 parts by mass of the acrylic polymer (solid content) and mixed to obtain a pressure-sensitive adhesive composition 1.

  Next, a release liner made of polyethylene terephthalate (PET) as a release sheet (trade name “SP-PET3811” manufactured by Lintec Corporation) is prepared, and the pressure-sensitive adhesive composition 1 obtained above is dried on the release surface. It apply | coated so that latter average thickness might be set to 30 micrometers, and the obtained coating film was heat-dried and the adhesive layer 1 was formed. Thereafter, a PET film (trade name “Lumirror”, manufactured by Toray Industries, Inc.) having an average thickness of 50 μm as a support was laminated on the pressure-sensitive adhesive layer 1 to prepare a pressure-sensitive adhesive sheet 1 for exfoliation.

(Examples 2 to 5)
Exemplified pressure-sensitive adhesive sheets 2 to 5 were prepared in the same manner as in Example 1 except that the amount (parts by mass) of rosin resin A in Example 1 was changed to the values shown in Table 1 below.

(Example 6)
In Example 1, instead of rosin-based resin A, a hydrogenated rosin glycerin ester resin having a softening point of 99 ° C. and a number average molecular weight of 400 (trade name “Pine Crystal KE-359” manufactured by Arakawa Chemical Industries, Ltd., hereinafter “ Except using rosin-based resin B "), an exfoliated pressure-sensitive adhesive sheet 6 was prepared in the same manner as in Example 1.

(Example 7)
In Example 1, instead of the rosin resin A, a hydrogenated rosin glycerin ester resin having a softening point of 128 ° C. and a number average molecular weight of 400 (trade name “Pine Crystal KE-604” manufactured by Arakawa Chemical Industries, Ltd., hereinafter “ Except using rosin-based resin C ”), the exfoliated pressure-sensitive adhesive sheet 7 was prepared in the same manner as in Example 1.

(Example 8)
In Example 1, instead of the monomer composition 1, 95 mol% of acrylic acid-2-ethylhexyl (2EHA), 4.97 mol% of acrylic acid (AAc), and 1,6-hexanediol diacrylate (HDDM) 0. For exfoliation of keratin in the same manner as in Example 1 except that an ethyl acetate solution (solid content: 40% by mass) of acrylic copolymer 2 obtained by copolymerizing monomer composition 2 consisting of 03 mol% was used. An adhesive sheet 8 was produced.

Example 9
In Example 1, instead of the monomer composition 1, 95 mol% of 2-ethylhexyl acrylate (2EHA), 4.97 mol% of 2-hydroxyethyl acrylate (2HEA), and 1,6-hexanediol diacrylate (HDDM) Same as Example 1 except that an ethyl acetate solution (solid content: 40% by mass) of acrylic copolymer 3 obtained by copolymerizing monomer composition 3 comprising 0.03 mol% was used. Thus, an exfoliating pressure-sensitive adhesive sheet 9 was produced.

(Comparative Examples 1-3)
In Example 1, exfoliated pressure-sensitive adhesive sheets 1r to 3r were prepared in the same manner as in Example 1 except that the blending amount (part by mass) of the rosin resin A was changed to the values shown in Table 1 below.

(Comparative Example 4)
In Example 1, instead of 15.0 parts by mass of rosin resin A, glycerin (manufactured by Asahi Denka Kogyo Co., Ltd., trade name “Japanese Pharmacopoeia Concentrated Glycerin”, molecular weight: 92.09, hereinafter referred to as “additive D”. ) Except having used 5.0 mass parts, it carried out similarly to the said Example 1, and produced the adhesive sheet 4r for exfoliating exfoliation.

(Comparative Example 5)
In Example 1, in place of 15.0 parts by mass of rosin resin A, isopropyl myristate (manufactured by Nikko Chemicals, trade name “NIKKOL IPM-EX”, molecular weight: 270.45, hereinafter referred to as “additive E”). ) Except having used 5.0 mass parts, it carried out similarly to the said Example 1, and produced the adhesive sheet 5r for exfoliating exfoliation.

(Comparative Example 6)
In Example 1, instead of 15.0 parts by mass of rosin resin A, polyethylene glycol (manufactured by Wako Pure Chemical Industries, trade name “PEG-200”, molecular weight: 194, hereinafter referred to as “additive F”) 5 Except having used 0.0 mass part, it carried out similarly to the said Example 1, and produced the adhesive sheet 6r for exfoliating keratin.

(Comparative Example 7)
In Example 8, a keratin exfoliating pressure-sensitive adhesive sheet 7r was produced in the same manner as in Example 8 except that the rosin resin A was not blended.

(Comparative Example 8)
In Example 1, instead of rosin resin A, C9 hydrogenated petroleum resin having a softening point of 100 ° C. and a number average molecular weight of 700 (trade name “Alcon P-100” manufactured by Arakawa Chemical Industries, Ltd., hereinafter “addition” Except for using “agent G”), a keratin exfoliation pressure-sensitive adhesive sheet 8r was prepared in the same manner as in Example 1.

(Comparative Example 9)
In Example 1, instead of 15.0 parts by mass of rosin-based resin A, exfoliating adhesive sheet 9r for exfoliating keratin in the same manner as in Example 1 except that 30.0 parts by mass of additive G was used. Produced.

(Comparative Example 10)
In Example 1, instead of rosin resin A, a terpene resin having a softening point of 115 ° C. and a number average molecular weight of 1600 (manufactured by Yashara Chemical Co., Ltd., trade name “YS Resin PX-1150N”, hereinafter referred to as “Additive H”). ) Was used in the same manner as in Example 1 to prepare an exfoliating pressure-sensitive adhesive sheet 10r.

(Comparative Example 11)
In Example 1, instead of 15.0 parts by mass of rosin resin A, exfoliating adhesive sheet 11r for exfoliating exfoliation was the same as Example 1 except that 30.0 parts by mass of additive H was used. Produced.

(Comparative Example 12)
In Example 1, instead of acrylic acid-2-ethylhexyl (2EHA), exfoliated pressure-sensitive adhesive sheet 12r was prepared in the same manner as in Example 1 except that acrylic acid-n-butyl (BA) was used. .

(Comparative Example 13)
A cellophane tape (trade name: Cellotape (registered trademark)) manufactured by Nichiban Co., Ltd. was used as the pressure-sensitive adhesive sheet 13r for exfoliation of Comparative Example 13. The main component of the cellophane tape adhesive is natural rubber.

  The storage elastic moduli at 0 ° C. and 32 ° C. of the pressure-sensitive adhesive layers 1 to 9 and 1r to 13r of the exfoliating pressure-sensitive adhesive sheets 1 to 9 and 1r to 13r obtained in the above Examples and Comparative Examples were measured using a viscoelasticity measuring device (manufactured by Rheometrics, device name “ DYNAMIC ANALYZER RDAII ”). The measurement results are shown in Table 2 below.

For the keratin exfoliating pressure-sensitive adhesive sheets 1 to 9 and 1r to 13r, the amount of exfoliated keratin was measured in accordance with the protein quantification method (Lowry method) as shown below. The measurement results are shown in Table 2 below.
<Measurement of amount of exfoliation>
First, the release sheet is removed from each exfoliating pressure-sensitive adhesive sheet, and the pressure-sensitive adhesive layer is adhered to pig skin (Yucatan Micro Pig (YMP Skin Kit), purchased from Nihon Charles River) for 5 minutes. The pressure-sensitive adhesive sheet for peeling was peeled at 180 ° peel at a peeling speed of 1 m / min.
The peeled exfoliated pressure-sensitive adhesive sheet was punched into 12 mmφ, and the amount of exfoliated corneum (protein amount, μg / cm ² ) was measured with a DC protein assay kit (Bio-Rad Laboratories). [Ref: F. Dreher, Colorimetric Method for Quantifying Human Stratum Corneum Removed by Adhesive-Tape-Stripping, Acta Derme Venesol (86), 1998;

  Also, the presence or absence of glue residue on the skin is visually observed. When there is no glue residue, “None”, when there is glue residue “Yes”, when there is some glue residue “Partial” ". The results are shown in Table 2 below. In addition, when there is adhesive residue, the amount of exfoliation cannot be measured, so that it was described as impossible to measure in the column of exfoliation.

  From Table 2, when the keratin exfoliation pressure-sensitive adhesive sheets 1 to 9 of the examples were used, there was no adhesive residue, and the amount of keratin exfoliation was greater than when the keratin exfoliation pressure-sensitive adhesive sheets 1r to 13r of comparative examples were used. .

Claims (6)

A stratum corneum peeling pressure-sensitive adhesive sheet having a support and a pressure-sensitive adhesive layer formed on the support,
The adhesive layer has a storage elastic modulus at 32 ° C. of 2.0 × 10 ^{5 to} 5.0 × 10 ⁵ Pa and a storage elastic modulus at 0 ° C. of 1.6 × 10 ^{6 to} 4.0 × 10 ^8. A pressure-sensitive adhesive sheet for exfoliating keratin, which is Pa.   The pressure-sensitive adhesive for exfoliation according to claim 1, wherein the pressure-sensitive adhesive layer is formed from a pressure-sensitive adhesive composition containing an acrylic polymer and a rosin resin having a softening point of 80 to 160 ° C by a ring and ball method. Sheet.   The acrylic polymer is a (meth) acrylic acid alkyl ester having an alkyl group having 6 to 12 carbon atoms, a monomer having a carboxyl group, a monomer having a hydroxyl group, and a nitrogen atom having no salt structure in the side chain The pressure-sensitive adhesive sheet for exfoliation according to claim 2, wherein the pressure-sensitive adhesive sheet is obtained by copolymerizing a monomer composition containing at least one monomer selected from the group consisting of monomers having the following.   The pressure-sensitive adhesive sheet for exfoliation according to claim 3, wherein the monomer composition further contains a monomer having a plurality of polymerizable unsaturated groups in the molecule.   The pressure-sensitive adhesive sheet for exfoliation according to claim 2, wherein the rosin resin has a number average molecular weight of 300 to 2,000.   The pressure-sensitive adhesive sheet for exfoliation according to claim 2, wherein the rosin resin is used in an amount of 10 to 40 parts by mass with respect to 100 parts by mass of the acrylic polymer.