JP2012002748A - Bio-device photographing apparatus - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a bio-device photographing apparatus capable of taking a picture in a condition that intensity irregularity is reduced in illumination light for illuminating a reaction part of a bio-device.SOLUTION: An apparatus has: a holding part 25 of a housing 2 for holding a bio-device 1 inserted to a storage chamber 23 from an entrance 24; a light reflecting member 3 disposed to be opposed to a reaction part 12 of the bio-device 1; a light source 4 for irradiating a light reflecting surface 30 of the light reflecting member 3 with light along a surface direction (S direction) in which a surface 1s of the bio-device 1 extends and for indirectly illuminating the reaction part 12 of the bio-device 1 with light reflected by the light reflecting surface 30 of the light reflecting member 3; and a photographing part 5 for photographing the reaction part 12 of the bio-device 1 indirectly illuminated by the light source 4.

Description

  The present invention relates to a biodevice imaging apparatus that images a reaction part with respect to a biodevice in which the state of the reaction part changes depending on components contained in an object to be measured such as blood, urine, and body fluid related to a living body.

  Patent Document 1 discloses, for example, a measurement method using an image sensor as a biodevice imaging apparatus for imaging a biodevice in which the status of a reaction unit changes according to a component contained in an object to be measured such as blood and urine related to a living body, and An apparatus is disclosed. According to this, as shown in FIG. 9, in order to irradiate the test piece 2X, three LEDs 4X as light sources are arranged at the same height at intervals of 120 degrees above the periphery of the test piece 2X. The test piece 2X is irradiated at an incident angle of 45 degrees toward the center of. A CMOS area sensor 8X is arranged above the test piece 2X.

  According to this, the light emitted from the plurality of LEDs 4X located above the test piece 2X is directly applied to the test piece 2X and directly illuminated. In this case, since it is direct illumination in which light emitted from the LED 4X is directly applied to the test piece 2X, there is usually a tendency that an uneven phenomenon occurs in which the central portion is bright and the peripheral portion is dark. For this reason, there is a limit in bringing the LED 4X closer to the test piece 2X, and it is necessary to move the LED 4X away from the test piece 2X. However, in this case, there is a problem that the dimension in the height direction of the housing 14X increases.

Patent No. 3774192

  The present invention has been made in view of the above-described circumstances, and illumination light that illuminates a reaction part in a biodevice in which the state of the reaction part changes according to components contained in a measurement target such as blood, urine, and body fluid It is an object of the present invention to provide a biodevice imaging apparatus capable of imaging the reaction part in a state where the intensity unevenness of the device is reduced.

  A biodevice imaging apparatus according to the present invention is an apparatus for imaging a change state of a reaction part of a biodevice, and (ii) a housing having an accommodating chamber, an accommodating chamber that communicates with the outside, and (ii) A housing part provided in the housing chamber of the housing and holding the biodevice inserted into the housing chamber from the entrance and exit, and (iii) a housing chamber of the housing so as to face the reaction part of the biodevice held in the housing holding part A light reflecting member having a light reflecting surface disposed on the housing, and (iv) provided in the housing chamber so as to face the light reflecting surface of the light reflecting member, and transmits light along a surface direction in which the surface of the biodevice extends. A light source that projects toward the light reflecting surface of the light reflecting member and indirectly illuminates the reaction part of the biodevice with the light reflected by the light reflecting surface of the light reflecting member; and (v) how Provided in the accommodation chamber of the ring comprises an imaging unit for photographing through the light reflecting surface of the light reflecting member and the reaction of the indirect illuminated biodevices light source.

  The biodevice means a device in which the state of the reaction part changes in accordance with components contained in an object to be measured typified by living body blood, urine, tears, sweat, body fluid and the like. The shape of the biodevice is not particularly limited. The light source is provided in the housing chamber of the housing so as to face the light reflecting surface of the light reflecting member. The light source may be anything as long as it can emit light, and examples thereof include LEDs and fluorescent lamps. The light source projects light toward the light reflecting surface of the light reflecting member along the surface direction in which the surface of the bio device extends, and indirectly reflects the reaction part of the bio device with the light reflected by the light reflecting surface of the light reflecting member. Illuminate. Indirect illumination is advantageous in reducing unevenness in the intensity of illumination light that illuminates the reaction part of the biodevice because light from the light source is prevented from directly entering the reaction part of the biodevice. Furthermore, the light source projects light toward the light reflecting surface of the light reflecting member along the surface direction in which the surface of the bio device extends, and reacts with the light reflected by the light reflecting surface of the light reflecting member. Illuminate. For this reason, the distance from a light source to a target (reaction part of a biodevice) is securable. In this case, the intensity unevenness of the illumination light that illuminates the reaction part of the biodevice can be reduced.

  According to the present invention, the illumination light for illuminating the reaction part of the biodevice is not direct light, but indirect light. Further, since the illumination distance from the light source to the reaction part of the biodevice can be increased, Unevenness of strength can be reduced. For this reason, the change state of the reaction part of a biodevice can be image | photographed favorably.

  According to the present invention, the reaction part of the biodevice is projected with light that is projected toward the light reflecting surface of the light reflecting member along the surface direction in which the surface of the bio device extends and reflected by the light reflecting surface of the light reflecting member. Indirect lighting is used. For this reason, size reduction in the direction which cross | intersects the surface direction where the surface of a biodevice extends among housings can be achieved.

1A is a plan view of a biodevice, and FIG. 2B is a side view of the biodevice according to the first embodiment. It is sectional drawing of a biodevice imaging device. It is a top view which shows the internal structure of a biodevice imaging device. (A) is a top view of the base | substrate arrange | positioned inside a biodevice imaging device, (B) is a front view of a base | substrate, (C) is a side view of a base | substrate. (A) is a right side view of the biodevice photographing apparatus, (B) is a plan view, (C) is a left side view, and (D) is a front view. It is a perspective view of a biodevice imaging device. It is a circuit diagram of a detection switch. It is a flowchart which shows a reading program. It is a figure explaining a prior art.

  Preferably, the photographing unit is provided to face the light reflecting surface of the light reflecting member in the accommodation chamber. In this case, the imaging unit receives light by reflecting the reflected light reflected in the reaction part of the biodevice by the light reflecting surface of the light reflecting member and causing the reflected light to travel along the surface direction in which the surface of the biodevice extends. In this case, the light reflecting surface of the light reflecting member is preferably shared for both indirect illumination by the light source and photographing by the photographing unit. Thereby, the number of parts of a light reflection member is reduced.

  In the direction orthogonal to the surface direction in which the surface of the biodevice extends, the imaging unit is provided at a position that is opposed to the light reflecting member and is separated from the light source with respect to the biodevice held by the holding unit. Preferably it is. In this case, it is suppressed that the light projected from the light source is directly received by the imaging unit without reaching the reaction unit of the biodevice.

  It is preferable that a base having the first mounting surface and the second mounting surface on the front and back sides and a detection switch for outputting a signal indicating completion of insertion of the biodevice inserted into the storage chamber from the entrance of the housing are provided. It is preferable that the light source is mounted on the first mounting surface of the base and the detection switch is mounted on the second mounting surface of the base. Since the base is shared by the light source and the detection switch, it can contribute to the reduction of the number of parts.

  In the storage chamber, the entrance / exit, the light reflecting member, the light source, and the imaging unit are preferably arranged in this order in the insertion direction in which the biodevice is inserted from the entrance / exit toward the holding unit. In this case, the housing can be thinned in a direction orthogonal to the insertion direction. Preferably, the light reflecting member can be moved forward and backward along the insertion direction of the biodevice while being inclined at a constant angle with respect to the holding portion. In this case, even if the type of the biodevice changes and the position of the reaction part of the biodevice changes in the insertion direction, the inclination angle of the light reflecting surface of the light reflecting member can be changed by moving the light reflecting member forward and backward. Since the position of the light reflecting member can be adjusted in the insertion direction while maintaining it, the reaction part of the biodevice can be well illuminated.

(Embodiment 1)
Hereinafter, Embodiment 1 of the present invention will be described. FIG. 1A shows a plan view of the biodevice 1. FIG. 1B shows a side view of the biodevice 1, and as shown in FIGS. 1A and 1B, the biodevice 1 includes a flat and thin case 10 having a thickness T1, and An inlet 11 opened on the upper surface, a sheet 14 having a reaction portion 12 formed by a plurality of lines 13 (13a, 13b) carrying antigens and / or antibodies, and a reaction portion 12 formed on the upper surface of the case 10. Is exposed to the outside, and a QR code 16 (identifier) exposed on the upper surface of the case 10 is provided.

  As shown in FIG. 1A, the reaction unit 12 and the QR code 16 are mutually connected in a direction (arrow B direction, width direction of the biodevice 1) that intersects the insertion direction (arrow A1 direction) of the biodevice 1 described later. It is installed next to it. The imaging area M includes the reaction unit 12 and the QR code 16 of the biodevice 1.

  As shown in FIG. 1B, the exposure port 15 includes inclined surfaces 15a and 15b facing each other in the directions of arrows A1 and A2, and inclined surfaces 15c and 15d facing each other in a direction crossing the directions of arrows A1 and A2. Have The inclined surfaces 15a to 15d are inclined so as to expand toward the upper side. For this reason, when the exposure port 15 is illuminated with light from above, no shadow appears in the reaction unit 12.

  The QR code 16 is an identifier for identifying information (for example, a calibration curve) relating to an inspection target to be inspected from other information. When the inspection liquid is dropped into the sheet 14 from the injection port 11 or the like, the inspection liquid moves to the reaction unit 12 along the sheet 14 due to surface tension or the like. In this case, the color of the line 13 (13a, 13b) of the reaction unit 12 changes depending on the components contained in the test solution. Depending on the color change state of the line 13 (13a, 13b), the composition and concentration of the test solution are determined, and the quality of the test component contained in the test solution is determined. In addition, the surface direction where the surface 1s of the biodevice 1 extends is shown as an arrow S direction.

  FIG. 2 is a cross-sectional view of the biodevice photographing apparatus according to the present embodiment. FIG. 3 shows a plan view of the internal structure. The biodevice photographing apparatus is an apparatus that photographs the change state of the reaction unit 12 of the biodevice 1. The housing 2 according to the present apparatus is thinned, and is formed by assembling a lower first housing 21 and an upper second housing 22 together. The housing 2 has a storage chamber 23 formed inside, and an entrance / exit 24 formed in one end portion 2e of the housing 2 so that the storage chamber 23 communicates with the outside. The entrance / exit 24 is formed on the bottom 2 b side of the housing 2. The holding portion 25 is provided in the storage chamber 23 of the housing 2 and is formed in the first housing 21. The holding portion 25 is a flat surface for holding the biodevice 1 inserted in the storage chamber 23 from the entrance 24 into the storage chamber 23. A holding surface 26 is provided. In addition, in FIG. 2, the direction which inserts the biodevice 1 is shown as arrow A1 direction. A direction in which the biodevice 1 held by the holding unit 25 is taken out is shown as an arrow A2 direction.

  As shown in FIG. 2, the mirror member 3 as a light reflecting member is disposed in the housing chamber 23 of the housing 2 so as to face the reaction unit 12 of the biodevice 1 held by the holding unit 25 of the housing 2 from above. ing. The mirror member 3 has a flat light reflecting surface 30. The light reflecting surface 30 of the mirror member 3 is inclined with respect to the horizontal holding surface 26 by an angle θ1 (about 45 °, see FIG. 2). The light reflecting surface 30 is inclined so as to descend linearly toward the entrance / exit 24.

  As shown in FIG. 2, the light source 4 is provided in the housing chamber 23 of the housing 2 so that the light emitting surface 40 of the light source 4 faces the light reflecting surface 30 of the mirror member 3. The light source 4 projects light toward the light reflecting surface 30 of the mirror member 3 along the surface direction (arrow S direction) in which the surface 1 s of the biodevice 1 extends, and is reflected by the light reflecting surface 30 of the mirror member 3. The reaction part 12 of the biodevice 1 is indirectly illuminated with the light that has been caused. For this reason, it is possible to ensure a long illumination distance from the light emitting surface 40 of the light source 4 to the target (the reaction part 12 of the biodevice 1) while downsizing the housing 2 in the height direction (arrow H direction). it can.

  In this case, the light emitting surface 40 of the light source 4 does not have to be excessively close to the reaction unit 12 of the biodevice 1 in the height direction of the housing 2 (the direction of the arrow H). For this reason, as described above, the illumination distance from the light source 1 to the reaction part 12 of the biodevice 1 is ensured favorably, so that unevenness in the intensity of illumination illuminating the reaction part 12 of the biodevice 1 can be reduced. Furthermore, according to the present embodiment, as described above, light is indirectly illuminated from the light source 4 to illuminate the reaction unit 12 of the biodevice 1, and therefore, illumination that illuminates the reaction unit 12 of the biodevice 1 compared to direct illumination. The advantage that light intensity unevenness can be reduced is obtained.

  As shown in FIG. 2, the photographing unit 5 is formed of an image sensor, and is provided in the first housing 21 via the photographing holder 50 in the housing chamber 23 of the housing 2. The imaging unit 5 captures the reaction unit 12 (image on the light reflection surface 30 of the mirror member 3) of the biodevice 1 that is indirectly illuminated by the light emitting surface 40 of the light source 4. Here, as shown in FIG. 2, the imaging unit 5 is in the storage chamber 23 in the plane direction (arrow S direction) in which the surface 1 s of the biodevice 1 extends, that is, in the insertion direction of the biodevice 1 (arrow A1 direction). The mirror member 3 is provided so as to face the light reflecting surface 30. In this case, the reflected light reflected by the reaction unit 12 of the biodevice 1 is incident on the light reflection surface 30 of the mirror member 3, and the image of the reaction unit 12 is reflected as an image on the light reflection surface 30 of the mirror member 3. The imaging unit 5 captures an image on the light reflecting surface 30 of the mirror member 3 (change state of the reaction unit 12 of the biodevice 1 and an image of the QR code 16).

  In other words, the reaction part 12 and the QR code 16 of the biodevice 1 are reflected as an image on the light reflecting surface 30 of the mirror member 3 located directly above the reaction part 12. The light of this image travels toward the photographing unit 5 along the arrow S direction and the arrow A1 direction, and is received by the photographing unit 5 and photographed by the photographing unit 5. Thus, the imaging unit 5 captures an image projected on the light reflecting surface 30 of the mirror member 3. According to this embodiment, the light reflection surface 30 of the mirror member 3 is shared by both indirect illumination by the light source 4 and photographing by the photographing unit 5. In this case, there is no need to provide a plurality of mirror members 3, the number of parts can be reduced, and it can contribute to miniaturization.

  In addition, as shown in FIG. 1, the space | interval of the lines 13a and 13b in the reaction part 12 of the biodevice 1 is set to (DELTA) L. However, when the image of the lines 13a and 13b reflected on the light reflecting surface 30 of the mirror member 3 in the tilted state is photographed by the photographing unit 5, the photographing unit 5 is affected by the inclination angle θ1 of the mirror member 3, so that ΔL is narrowed. Taken at 5. For this reason, it is necessary to ensure the actual space | interval (DELTA) L of the lines 13a and 13b in the reaction part 12 of the biodevice 1 from a viewpoint of imaging | photography so that lines 13a and 13b can fully be identified also in the image in the light reflective surface 30. is there. However, if the interval ΔL in the biodevice 1 is excessively increased, the distance from the injection port 11 to the line 13a and the distance from the injection port 11 to the line 13b in the biodevice 1 are greatly different. This may affect the reachability of the test solution injected from the line 13a, 13b.

  According to the present embodiment, as can be understood from FIG. 2, the imaging unit 5 includes the surface direction (arrow S direction) of the biodevice 1 of the holding surface 26 of the holding unit 25 and the insertion direction (arrow A1 direction) of the biodevice 1. ) Facing the light reflecting surface 30 of the mirror member 3. Further, the imaging unit 5 has an arrow S direction (a surface direction in which the surface 1s of the biodevice 1 extends) and an arrow A1 direction (an insertion direction of the biodevice 1) with respect to the biodevice 1 on the holding surface 26 of the holding unit 25. In FIG. 3, the light source 4 is provided at a position separated from the light emitting surface 40. In other words, with respect to the biodevice 1 on the holding surface 26 of the holding unit 25, imaging is performed in the arrow S direction (the surface direction in which the surface 1s of the biodevice 1 extends) and the arrow A1 direction (the insertion direction of the biodevice 1). The part 5 is provided at a position farther from the light emitting surface 40 of the light source 4. In this case, as can be understood from FIG. 2, the light emitting surface 40 of the light source 4 faces the light reflecting surface 30 of the mirror member 3 in the arrow S direction and the arrow A1 direction, but does not face the photographing unit 5. . The back surface 40r of the light source 4 faces the photographing unit 5. For this reason, it is suppressed that the light emitted from the light emitting surface 40 of the light source 4 is directly received by the photographing unit 5. For this reason, the imaging | photography by the imaging | photography part 5 can be performed favorable.

  According to this embodiment, the base | substrate 6 which has the 1st mounting surface 61 and the 2nd mounting surface 62 in the front and back is provided so that it can understand from FIG. 2 and FIG. A detection switch 63 for outputting a signal indicating completion of insertion of the biodevice 1 inserted in the direction of the arrow A1 from the entrance / exit 24 of the housing 2 into the storage chamber 23 is provided. The light source 4 is an LED and is mounted on the first mounting surface 61 of the base 6. The detection switch 63 is mounted on the second mounting surface 62 of the base 6. Thus, since the base 6 is shared by the light source 4 and the detection switch 63, it can contribute to the reduction of the number of parts. 4A, 4B, and 4C show the base 6 on which the light source 4 and the detection switch 63 are mounted. As shown in FIG. 4C, the light emitting surface 40 of the light source 4 is directed upward (in the direction of the arrow U1) toward the light reflecting surface 30 of the mirror member 3. The number of light sources 4 is singular (one). Therefore, as shown in FIG. 3, the light from the light emitting surface 40 of the light source 4 strikes the light reflecting surface 30 of the mirror member 3 while spreading laterally. FIG. 7 shows a circuit diagram in which the light source 4 is turned on when the detection switch 63 is turned on.

  As shown in FIG. 3, an inlet guide portion 27 that guides the side surface 1 h of the biodevice 1 is provided in the vicinity of the inlet / outlet 24 in the accommodation chamber 23 so as to face each other. Further, a slide guide 28 is provided in the storage chamber 23. The slide guide 28 has a substantially U-shape in plan view, a pair of guide surfaces 28a for guiding the side surface 1h of the biodevice 1, and a stopper surface 28c against which the distal end portion 1a of the biodevice 1 to be inserted hits. It has a guide surface 28h (see FIG. 2) that guides the biodevice 1 while holding the upper side of the distal end portion 1a while guiding it to a fixed position in the height direction (H direction).

  As shown in FIG. 3, the distance LA between the guide surfaces 28 a corresponds to the width dimension of the biodevice 1. As a result, when the biodevice 1 is inserted into the accommodation chamber 23 of the housing 2 in the arrow A1 direction from the entrance / exit 24, the position in the width direction (arrow B direction) of the biodevice 1 can be defined as a fixed position of the accommodation chamber 23.

  According to the present embodiment, as shown in FIG. 3, the insertion port 29 into which the one end portion 7 a of the USB cable 7 as a cable having a function of supplying power and control information to the photographing unit 5 is inserted in the side wall of the housing 2. Is formed. The housing 2 has no openings other than the insertion port 29 and the entrance / exit 24. For this reason, it can suppress that external light penetrate | invades into the storage chamber 23 as disturbance light, and influences imaging | photography.

  When the apparatus is used, since the USB cable 7 is inserted into the insertion port 29 of the housing 2, the insertion port 29 is substantially closed. Furthermore, since the biodevice 1 is inserted into the entrance / exit 24 of the housing 2 in the direction of the arrow A1, the entrance / exit 24 is mostly closed. For this reason, when the apparatus is used, light outside the housing 2 is suppressed from entering the housing 2. That is, external light is prevented from entering the housing 2 as disturbance light. Thereby, the light reflection of the mirror member 3 and the photographing by the photographing unit 5 can be favorably performed while avoiding the influence of the external disturbance hole. Therefore, the imaging accuracy of the reaction unit 12 of the biodevice 1 is ensured.

  As shown in FIG. 2, the base 6 or the mirror member 3 is disposed between the entrance / exit 24 and the photographing unit 5 in the arrow A1 direction. Even if external light enters the storage chamber 23 from the entrance / exit 24 of the housing 2 as intrusion light LP, the intrusion light LP is blocked by the base 6 or the mirror member 3 in the storage chamber 23. It is possible to suppress LP from reaching the imaging unit 5. For this reason, the imaging unit 5 can satisfactorily capture the reaction unit 12 and the QR code 16 without being affected by the intrusion light LP.

  At the time of use, in a state where the biodevice 1 is detached from the housing 2, the inspector supplies the test solution by dropping it into the injection port 11 of the biodevice 1. When the inspection liquid reaches the reaction part 12 of the sheet 14, the color of the reaction part 12 changes. Specifically, the colors of the plurality of lines 13 (13a, 13b) of the reaction unit 12 change according to the component concentration contained in the test solution. By measuring the color change status of the plurality of lines 13 (13a, 13b), the test status of the test liquid can be grasped.

  According to the present embodiment, when the biodevice 1 is inspected, the one end portion 7a of the USB cable 7 is inserted from the insertion port 29 of the housing 2 and is connected to the USB connector (connector) 55 of the photographing unit 5. Power is supplied to the photographing unit 5 from a personal computer as a device. Then, the user grasps the proximal end portion 1c of the biodevice 1, and moves the biodevice 1 from the distal end portion 1a side to the accommodation chamber 23 of the housing 2 through the entrance / exit 24 in a substantially horizontal direction (arrow A1 direction). insert. In this case, the biodevice 1 is guided by the entrance guide 27 and guided to a fixed position along the guide surface 28 a of the slide guide 28. In this case, the height guide surface 28h of the slide guide 28 is guided to a fixed position in the height direction (arrow H direction) to be guided while pressing the upper side of the distal end portion 1a of the biodevice 1. And the biodevice 1 inserted in the storage chamber 23 is hold | maintained along the horizontal direction on the holding surface 26 of the holding | maintenance part 25 until it contacts the stopper surface 28c. Even when the biodevice 1 is held on the holding surface 26 of the holding portion 25 in this way, the base end portion 1c of the biodevice 1 is exposed to the outside of the housing 2 for removal. Yes.

  When the biodevice 1 is thus inserted into the housing 2 in the direction of the arrow A1, the operation portion 63x of the detection switch 63 is operated by being pressed by the distal end portion 1a of the case 10 of the biodevice 1, and the on signal is transmitted to the light source 4 And the imaging unit 5 is made to output. When the light source 4 is turned on, light (for example, green) is emitted from the light emitting surface 40 of the light source 4 toward the light reflecting surface 30 of the mirror member 3. The light reflected by the light reflecting surface 30 of the mirror member 3 faces downward and enters the reaction unit 12 of the biodevice 1. Thereby, the reaction part 12 of the biodevice 1 is indirectly illuminated by light (for example, green) from the light emitting surface 40 of the light source 4. The reaction part 12 of the biodevice 1 is reflected on the light reflecting surface 30 of the mirror member 3. The photographing unit 5 photographs an image on the light reflecting surface 30 of the mirror member 3, that is, a color change state of the line 13 (13 a, 13 b) of the reaction unit 12. The shooting area M by the shooting unit 5 is shown in FIG. As described above, since the coloring state of the line 13 (13a, 13b) of the reaction unit 12 and the QR code 16 are photographed at once, the number of photographing is reduced. Here, as shown in FIG. 1A, the image photographed in the photographing area M includes the line 13 (13 a, 13 b) and the QR code 16 of the reaction unit 12 of the biodevice 1. The captured QR code 16 signal is input to the personal computer via the USB cable 7. The personal computer reads the QR code 16 and reads inspection information (such as a calibration curve) based on the QR code 16.

  In this case, a representative example of the processing form of the personal computer is shown in FIG. As shown in FIG. 8, first, an imaging signal is output, and the imaging unit 5 causes the image of the line 13 (13a, 13b) and the image of the QR code 16 of the reaction unit 12 of the biodevice 1 to be captured (step S2). . In this case, the image is adjusted by adjusting gain adjustment, offset adjustment, white balance adjustment, exposure time, etc., and a clear image is captured. Next, correction such as noise removal and luminance unevenness correction is performed on the captured image to correct a flat image (step S4). Next, the area of the QR code 16 is extracted from the obtained image, and the QR code 16 is decoded (step S6). In this case, information (a calibration curve or the like) related to the QR code 16 is read from the information stored in the memory area.

  Next, the brightness value of the line 13 (13a, 13b) of the reaction unit 12 of the biodevice 1 is taken in, and the peak of the brightness value of the line 13 (13a, 13b) with respect to the baseline is detected (step S8). Based on the ratio (A / B) of the lightness peaks of the two lines 13 (13a, 13b) of the reaction unit 12, the concentration (C) of the test component contained in the test solution is obtained from a calibration curve or the like (step) S10). The density data of the test component is stored in the memory area and the test information is displayed on the personal computer screen (step S12). When the inspection is completed, the user holds the base end portion 1c of the case 10 of the biodevice 1 with a finger and removes it from the housing 2.

  As described above, according to the present embodiment, the light emitting surface 40 of the light source 4 is along the surface direction (arrow S direction) in which the surface 1s of the biodevice 1 extends, that is, the insertion direction of the biodevice 1 (arrow A1). (Direction), light is projected toward the light reflecting surface 30 of the mirror member 3, and the reaction part 12 of the biodevice 1 is indirectly illuminated with the light reflected by the light reflecting surface 30 of the mirror member 3. . Indirect illumination is advantageous in reducing unevenness in intensity of illumination light that illuminates the line 13 (13a, 13b) of the reaction unit 12 of the biodevice 1 as compared to direct illumination.

  Furthermore, according to the present embodiment, the light source 4 emits light along the surface direction (arrow S direction) in which the surface 1 s of the biodevice 1 extends, that is, along the insertion direction (arrow A1 direction) of the biodevice 1. While projecting toward the light reflecting surface 30 of the mirror member 3, the reaction part 12 of the biodevice 1 is illuminated with the light reflected by the light reflecting surface 30 of the mirror member 3. Such a light propagation method is adopted. For this reason, if the illumination distance from the light source 4 to the target (the reaction part 12 of the biodevice 1) can be ensured while reducing the size of the housing 2 in the height direction (arrow H direction), and the illumination distance can be secured long, This is advantageous in reducing unevenness in the intensity of illumination light that illuminates the reaction portion 12 of the device 1.

  According to the present embodiment, as described above, light is projected toward the light reflecting surface 30 of the mirror member 3 along the surface direction (arrow S direction, arrow A1 direction) in which the surface 1s of the biodevice 1 extends. A method of indirectly illuminating the reaction part 12 of the biodevice 1 with the light reflected by the light reflecting surface 30 of the member 3 is employed. For this reason, size reduction in the direction (the height direction of the housing 2, the arrow H direction) which cross | intersects the surface direction (arrow S direction) where the surface 1s of the biodevice 1 extends among the housings 2 can be achieved. Here, the arrow S direction corresponds to the insertion direction (arrow A1 direction) in which the biodevice 1 is inserted from the entrance / exit 24 of the housing 2 toward the holding portion 25.

  In addition, as a conventional technique, a structure in which a diffusion plate or a light guide plate is installed is often adopted. However, according to the present embodiment, light from the light source 4 is directed in the surface direction of the biodevice 1 (arrow S direction) and It propagates toward the light reflecting surface 30 of the mirror member 3 along the insertion direction (arrow A1 direction) of the biodevice 1, reflects it at the light reflecting surface 30, and makes the reflected light enter the reaction part 12 of the biodevice 1. The method is adopted. For this reason, it is not necessary to adopt a structure in which a light guide plate that guides light by guiding it to the reaction unit 12 is provided in the accommodation chamber, which can contribute to cost reduction and avoidance of complexity of the structure.

  According to the present embodiment, as shown in FIG. 2, in the accommodation chamber 23 of the housing 2, in the insertion direction (arrow A <b> 1 direction) in which the biodevice 1 is inserted from the entrance / exit 24 of the housing 2 toward the holding unit 25. The doorway 24, the mirror member 3, the light source 4, and the photographing unit 5 are arranged in this order. In this case, in the direction (arrow H direction) perpendicular to the insertion direction (arrow A1 direction), the height direction (arrow H direction) dimension of the housing 2 can be reduced, so this device becomes a handy type and is portable. It becomes easy.

  According to the present embodiment, as shown in FIG. 2, the mirror member 3 can be moved forward and backward along the insertion direction (arrow A1 direction) of the biodevice 1 while being inclined at a constant angle with respect to the holding portion 25. Has been. That is, as shown in FIG. 2, the mirror support portion 32 having the inclined surface 32 c is provided in the housing chamber 23 of the housing 2. The inclined surface 32c is linearly inclined downward as it approaches the doorway 24 in the insertion direction (arrow A1 direction). As shown in FIG. 3, in the direction (arrow B direction) intersecting the insertion direction (arrow A1 direction) in which the biodevice 1 is inserted, a plurality (two) of projection-wall-shaped mirror support portions 32 are: They are arranged at intervals. The pressing member 33 is applied to the back surface 32k of the mirror member 3 in a state where the end 3e of the mirror member 3 in the direction intersecting the arrow A1 direction (arrow B direction) is placed on the inclined surface 32c of the mirror support portion 32. Then, the male screw of the attachment bolt 34 (attachment tool) passed through the pressing member 33 is screwed into the screw hole of the mirror support portion 32. Thus, the mirror member 3 is detachably held on the inclined surface 32c of the mirror support portion 32. In this case, the mirror member 3 can be moved in the direction of arrow E (see FIG. 2) along the inclined surface 32c of the mirror support portion 32 with the mounting bolt 34 loosened or removed. In this case, it is possible to adjust the position of the mirror member 3 in the direction of the arrow B1 while maintaining the inclination angle θ1 of the mirror member 3 with respect to the holding surface 26, and thus to adjust the position of the mirror member 3 in the direction of the arrow A1. In this case, even when the size or type of the biodevice 1 changes and the position of the reaction portion 12 of the biodevice 1 varies in the direction of the arrow A1, the mirror member 3 is moved along the inclined surface 32c of the mirror support portion 32. By moving forward and backward, the position of the mirror member 3 can be adjusted while maintaining the inclination angle θ1 of the light reflecting surface 30 of the mirror member 3. For this reason, even if the size and type of the biodevice 1 are changed, the reaction part 12 of the biodevice 1 can be favorably illuminated.

(Embodiment 2)
This embodiment has basically the same configuration and the same operation and effect as the first embodiment. However, in the above-described first embodiment, although not particularly illustrated, the number of the light sources 4 mounted on the base 6 is single, but is plural.

(Other)
The present invention is not limited to the embodiments described above and shown in the drawings, and can be implemented with appropriate modifications within the scope not departing from the gist. The detection switch may be mounted on the outer wall portion of the housing, and the user may operate the detection switch of the housing with a fingertip to cause the light source 4 to emit light and start photographing of the photographing unit 5. A bar code may be employed instead of the QR code 16.

  1 is a biodevice, 10 is a case, 12 is a reaction part, 13 is a line, 2 is a housing, 23 is a storage chamber, 24 is an entrance / exit, 25 is a holding part, 26 is a holding surface, 3 is a mirror member (light reflecting member) , 30 is a light reflecting surface, 32 is a mirror support section, 4 is a light source, 5 is a photographing section, 6 is a base, 63 is a detection switch, and 7 is a USB cable.

Claims (6)

An apparatus for photographing the change state of the reaction part of a biodevice,
A housing having a storage chamber and an entrance that allows the storage chamber to communicate with the outside;
A holding part that is provided in the housing chamber of the housing and holds the biodevice inserted into the housing chamber from the entrance;
A light reflecting member having a light reflecting surface disposed in the housing chamber of the housing so as to face the reaction part of the biodevice held in the holding part of the housing;
It is provided in the storage chamber of the housing so as to face the light reflecting surface of the light reflecting member, and directs light toward the light reflecting surface of the light reflecting member along a surface direction in which the surface of the biodevice extends. A light source for projecting and indirectly illuminating the reaction part of the biodevice with light reflected by the light reflecting surface of the light reflecting member;
A biodevice imaging apparatus comprising: an imaging unit that is provided in the housing chamber of the housing and that images the reaction unit of the biodevice indirectly illuminated by the light source through the light reflecting surface of the light reflecting member.   In Claim 1, The said imaging | photography part is provided so that it may oppose the said light reflection surface of the said light reflection member in the said storage chamber, The reflected light reflected in the said reaction part of the said biodevice is the said light reflection member. The light reflecting surface of the light reflecting member is reflected along the surface direction in which the surface of the biodevice extends, and the light reflecting surface of the light reflecting member is used for indirect illumination by the light source and the photographing. Biodevice imaging device shared by both departments.   In Claim 1 or 2, in the direction orthogonal to the surface direction in which the surface of the biodevice extends, the imaging unit faces the biodevice held by the holding unit while facing the light reflecting member. On the other hand, a biodevice photographing apparatus provided at a position separated from the light source.   The signal indicating completion of insertion of the biodevice inserted into the storage chamber from the entrance / exit of the housing, and a base having the first mounting surface and the second mounting surface on the front and back sides, respectively, is output. A biodevice photographing apparatus in which a detection switch is provided, the light source is mounted on the first mounting surface of the base, and the detection switch is mounted on the second mounting surface of the base.   5. The inlet / outlet, the light reflecting member, the light source, and the imaging in the storage chamber in the insertion direction in which the biodevice is inserted from the inlet / outlet toward the holding unit. The biodevice imaging apparatus is arranged in the order of the parts, and the housing is thinned in a direction orthogonal to the insertion direction.   6. The biodevice imaging according to claim 1, wherein the light reflecting member is capable of moving forward and backward along the insertion direction of the biodevice while being inclined at a constant angle with respect to the holding portion. apparatus.

Images