JP2011530277A - Ebv(エプスタイン−バーウイルス)潜在性膜タンパク質(lmp1)の細胞内領域に結合する抗体を含んでなる医薬組成物 - Google Patents

Ebv(エプスタイン−バーウイルス)潜在性膜タンパク質(lmp1)の細胞内領域に結合する抗体を含んでなる医薬組成物 Download PDF

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JP2011530277A
JP2011530277A JP2011521593A JP2011521593A JP2011530277A JP 2011530277 A JP2011530277 A JP 2011530277A JP 2011521593 A JP2011521593 A JP 2011521593A JP 2011521593 A JP2011521593 A JP 2011521593A JP 2011530277 A JP2011530277 A JP 2011530277A
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lmp1
antibody
amino acid
acid sequence
ebv
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JP2011530277A5 (enExample
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岡 忠 正 大
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サントル、ナショナール、ド、ラ、ルシェルシュ、シアンティフィク、(セーエヌエルエス)
ユニベルシテ・クロード・ベルナール・リヨン・プルミエ
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Publication of JP2011530277A publication Critical patent/JP2011530277A/ja
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/085Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2011521593A 2008-08-08 2009-08-07 Ebv(エプスタイン−バーウイルス)潜在性膜タンパク質(lmp1)の細胞内領域に結合する抗体を含んでなる医薬組成物 Pending JP2011530277A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08162083 2008-08-08
EP08162083.3 2008-08-08
PCT/EP2009/060277 WO2010015705A1 (en) 2008-08-08 2009-08-07 Pharmaceutical compositions comprising antibodies binding to the intracellular domain of ebv (epstein-barr virus) latent membrane protein-1 (lmp1)

Publications (2)

Publication Number Publication Date
JP2011530277A true JP2011530277A (ja) 2011-12-22
JP2011530277A5 JP2011530277A5 (enExample) 2012-09-06

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ID=40210594

Family Applications (1)

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JP2011521593A Pending JP2011530277A (ja) 2008-08-08 2009-08-07 Ebv(エプスタイン−バーウイルス)潜在性膜タンパク質(lmp1)の細胞内領域に結合する抗体を含んでなる医薬組成物

Country Status (5)

Country Link
US (1) US20120107319A1 (enExample)
EP (1) EP2331572A1 (enExample)
JP (1) JP2011530277A (enExample)
CN (1) CN102177177A (enExample)
WO (1) WO2010015705A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012072516A1 (en) 2010-11-29 2012-06-07 Centre National De La Recherche Scientifique (Cnrs) Barf1 a diagnostic and prognostic marker for epstein-barr virus (ebv)-associated lymphoma
CN103145849B (zh) * 2013-02-18 2014-06-11 冯振卿 嵌合抗原受体及其用途
AU2017306301B2 (en) 2016-08-02 2023-12-07 Dana-Farber Cancer Institute, Inc. LMP1-expressing cells and methods of use thereof
CN111647564B (zh) * 2020-05-18 2023-07-04 李欣 抗eb病毒lmp1的单克隆抗体及其细胞株和应用
MX2024007528A (es) 2021-12-23 2024-08-30 Sana Biotechnology Inc Linfocitos t del receptor de antígeno quimérico (car) para el tratamiento de enfermedades autoinmunitarias y métodos asociados.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005511047A (ja) * 2001-12-04 2005-04-28 デイナ−ファーバー キャンサー インスティチュート,インコーポレイテッド 潜伏期膜タンパク質に対する抗体およびそれらの使用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1229043A1 (en) * 2001-01-30 2002-08-07 Cyto-Barr B.V. Peptides derived from Epstein Barr virus (EBV) proteins LMP1, LMP2 and BARF1 antibody reagents reactive therewith

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005511047A (ja) * 2001-12-04 2005-04-28 デイナ−ファーバー キャンサー インスティチュート,インコーポレイテッド 潜伏期膜タンパク質に対する抗体およびそれらの使用

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6014007968; J. Immunol. Methods, 2004, Vol.287, pp.21-30 *
JPN6014007969; J. Clin. Pathol., 1995, Vol.48, pp.438-442 *
JPN6014007971; J. Virol., 1985, Vol.55, No.3, pp.710-720 *

Also Published As

Publication number Publication date
EP2331572A1 (en) 2011-06-15
WO2010015705A1 (en) 2010-02-11
CN102177177A (zh) 2011-09-07
US20120107319A1 (en) 2012-05-03

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