JP2011520813A5 - - Google Patents

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Publication number
JP2011520813A5
JP2011520813A5 JP2011508670A JP2011508670A JP2011520813A5 JP 2011520813 A5 JP2011520813 A5 JP 2011520813A5 JP 2011508670 A JP2011508670 A JP 2011508670A JP 2011508670 A JP2011508670 A JP 2011508670A JP 2011520813 A5 JP2011520813 A5 JP 2011520813A5
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JP
Japan
Prior art keywords
nucleic acid
particles
peptide
acid complex
polysaccharide
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JP2011508670A
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English (en)
Japanese (ja)
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JP2011520813A (ja
JP5763525B2 (ja
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Priority claimed from PCT/US2009/043158 external-priority patent/WO2009137689A2/en
Publication of JP2011520813A publication Critical patent/JP2011520813A/ja
Publication of JP2011520813A5 publication Critical patent/JP2011520813A5/ja
Application granted granted Critical
Publication of JP5763525B2 publication Critical patent/JP5763525B2/ja
Expired - Fee Related legal-status Critical Current
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JP2011508670A 2008-05-07 2009-05-07 粒子からの核酸複合体の送達 Expired - Fee Related JP5763525B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5104108P 2008-05-07 2008-05-07
US61/051,041 2008-05-07
PCT/US2009/043158 WO2009137689A2 (en) 2008-05-07 2009-05-07 Delivery of nucleic acid complexes from particles

Publications (3)

Publication Number Publication Date
JP2011520813A JP2011520813A (ja) 2011-07-21
JP2011520813A5 true JP2011520813A5 (es) 2012-06-28
JP5763525B2 JP5763525B2 (ja) 2015-08-12

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ID=40910992

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Application Number Title Priority Date Filing Date
JP2011508670A Expired - Fee Related JP5763525B2 (ja) 2008-05-07 2009-05-07 粒子からの核酸複合体の送達

Country Status (5)

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US (1) US8936811B2 (es)
EP (1) EP2296630A2 (es)
JP (1) JP5763525B2 (es)
CA (1) CA2723192A1 (es)
WO (1) WO2009137689A2 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2296630A2 (en) 2008-05-07 2011-03-23 SurModics, Inc. Delivery of nucleic acid complexes from particles
KR101209265B1 (ko) * 2008-12-26 2012-12-06 주식회사 삼양바이오팜 음이온성 약물 함유 약제학적 조성물 및 그 제조방법
CA2758260A1 (en) 2009-04-08 2010-10-14 Surmodics, Inc. Controlled release devices and methods for delivery of nucleic acids
WO2010118213A2 (en) * 2009-04-08 2010-10-14 Surmodics, Inc. Particles for delivery of nucleic acids and related devices and methods
EP2386647A1 (de) * 2010-05-10 2011-11-16 Qiagen GmbH Verfahren zur Transfektion einer eurkaryotischen Zelle
US20110319473A1 (en) * 2010-06-29 2011-12-29 Surmodics, Inc. Compositions and methods for enhancement of nucleic acid delivery
US8946170B2 (en) * 2010-07-21 2015-02-03 Allergan, Inc. Sustained release siRNA for ocular drug delivery
US20130302405A1 (en) * 2010-11-05 2013-11-14 Ezaki Glico Co., Ltd. Amino sugar-containing glucan, method for producing same, and use thereof
US8901092B2 (en) 2010-12-29 2014-12-02 Surmodics, Inc. Functionalized polysaccharides for active agent delivery
US9551680B2 (en) 2013-06-28 2017-01-24 Verily Life Sciences Llc Chemically reactive enzyme immobilization
US9441258B2 (en) * 2013-06-28 2016-09-13 Verily Life Sciences LLP Enzyme immobilization by crosslinking
US9750445B2 (en) 2013-06-28 2017-09-05 Verily Life Sciences Llc Porous polymeric formulation prepared using porogens
US9828620B2 (en) 2013-06-28 2017-11-28 Verily Life Sciences Llc Porous polymeric formulation prepared using monomer
CN105764491A (zh) 2013-12-09 2016-07-13 度瑞公司 药物活性剂复合物、聚合物复合物,以及包括其的组合物和方法
US9987228B2 (en) 2014-11-18 2018-06-05 National Institute For Materials Science Method for producing porous particle
JP6599560B2 (ja) * 2015-12-18 2019-10-30 サムヤン バイオファーマシューティカルズ コーポレイション 陰イオン性薬物を含有する高分子ミセルの製造方法
KR101882133B1 (ko) * 2017-02-21 2018-07-25 성균관대학교산학협력단 핵산과 결합 가능한 펩타이드를 이용하여 핵산을 분리하는 방법
US11590080B2 (en) 2017-12-18 2023-02-28 C.R. Bard, Inc. Drug-loaded biodegradable microbead compositions including drug-containing vesicular agents
JP2021506871A (ja) * 2017-12-18 2021-02-22 シー・アール・バード・インコーポレーテッドC R Bard Incorporated 薬物充填マイクロビーズ組成物、塞栓組成物および関連の方法
WO2021072385A1 (en) * 2019-10-10 2021-04-15 University Of Maryland, Baltimore Compositions and methods for delivering nucleic acids to cells

Family Cites Families (107)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2668156A (en) * 1950-04-06 1954-02-02 Nat Starch Products Inc Unsaturated starch compounds and insoluble derivatives thereof
US4079025A (en) 1976-04-27 1978-03-14 A. E. Staley Manufacturing Company Copolymerized starch composition
US4060506A (en) * 1976-04-27 1977-11-29 A. E. Staley Manufacturing Company Starch acrylamides and the method for preparing the same
US4638045A (en) * 1985-02-19 1987-01-20 Massachusetts Institute Of Technology Non-peptide polyamino acid bioerodible polymers
US5160745A (en) * 1986-05-16 1992-11-03 The University Of Kentucky Research Foundation Biodegradable microspheres as a carrier for macromolecules
CA2050911C (en) * 1989-05-04 1997-07-15 Thomas R. Tice Encapsulation process and products therefrom
EP0405917A1 (en) 1989-06-26 1991-01-02 Sequa Chemicals Inc. Starch polymer graft
US5116927A (en) * 1989-06-27 1992-05-26 Sequa Chemicals, Inc. Starch polymer graft composition and method of preparation
IL98087A (en) 1990-05-04 1996-11-14 Perio Prod Ltd Preparation for dispensing drugs in the colon
US5626863A (en) * 1992-02-28 1997-05-06 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US5736371A (en) * 1991-06-04 1998-04-07 A Et S Biovecteurs Biodegradable particulate vector for transporting molecules having biological activity
WO1993009176A2 (en) 1991-10-29 1993-05-13 Clover Consolidated, Limited Crosslinkable polysaccharides, polycations and lipids useful for encapsulation and drug release
ATE192487T1 (de) * 1992-02-13 2000-05-15 Surmodics Inc Immobilisierung eines chemischen spezies in einer vernetzten matrix
DE4210334A1 (de) 1992-03-30 1993-10-07 Stoess & Co Gelatine Biologisch abbaubares, wasserresistentes Polymer-Material
US6277899B1 (en) 1992-08-03 2001-08-21 Novamont S.P.A. Biodegradable polymeric composition
US5514379A (en) * 1992-08-07 1996-05-07 The General Hospital Corporation Hydrogel compositions and methods of use
US5414075A (en) 1992-11-06 1995-05-09 Bsi Corporation Restrained multifunctional reagent for surface modification
US5272181A (en) 1992-11-18 1993-12-21 Evergreen Solutions, Inc. Biodegradable expanded foam material
US5488102A (en) * 1992-11-30 1996-01-30 Ciba Geigy Corporation Polymerisable carbohydrate esters, polymers therefrom and their use
SE500964C2 (sv) 1993-01-19 1994-10-10 Medicarb Ab Fast bärare med modifierad yta varvid modifikationen åstadkommes genom en primer innehållande en polysackarid och förfarande för framställning av en sådan bärare
WO1994022919A1 (en) * 1993-04-07 1994-10-13 Alko Group Ltd. Applications and methods for the preparation of fatty acid esters of polysaccharides
US5773021A (en) * 1994-03-14 1998-06-30 Vetoquinol S.A. Bioadhesive ophthalmic insert
US5466233A (en) * 1994-04-25 1995-11-14 Escalon Ophthalmics, Inc. Tack for intraocular drug delivery and method for inserting and removing same
US5658592A (en) 1994-05-13 1997-08-19 Kuraray Co., Ltd. Medical crosslinked polymer gel of carboxylic polysaccharide and diaminoalkane
EP0769063A1 (en) * 1994-06-27 1997-04-23 The Johns Hopkins University Targeted gene delivery system
GB9514285D0 (en) 1995-07-13 1995-09-13 Univ Nottingham Polymeric lamellar substrate particles for drug delivery
TW362100B (en) 1995-07-21 1999-06-21 Novartis Ag The preparation and use of photochemically cross-linked polysaccharide derivatives having no photopolymerisable functional groups
JP2997995B2 (ja) * 1995-09-13 2000-01-11 日本コーンスターチ株式会社 生分解性樹脂組成物の水系分散液
US5714360A (en) * 1995-11-03 1998-02-03 Bsi Corporation Photoactivatable water soluble cross-linking agents containing an onium group
CA2173818A1 (fr) 1996-04-10 1997-10-11 Francois Chouinard Comprime pharmaceutique a liberation controlee contenant un support a base d'amylose reticule et d'hydroxypropylmethylcellulose
US20080131512A1 (en) 1996-07-01 2008-06-05 Wilhelmus Everhardus Hennink Biodegradable hydrogels
US5980948A (en) * 1996-08-16 1999-11-09 Osteotech, Inc. Polyetherester copolymers as drug delivery matrices
FR2753902B1 (fr) * 1996-09-27 1999-04-02 Ioualalen Karim Nouveau type de matrice ionique biodegradable de polarite interne modulable a polymere greffe
US5879707A (en) * 1996-10-30 1999-03-09 Universite De Montreal Substituted amylose as a matrix for sustained drug release
EP0842657A1 (en) * 1996-11-19 1998-05-20 OctoPlus B.V. Microspheres for controlled release and processes to prepare these microspheres
US5866165A (en) * 1997-01-15 1999-02-02 Orquest, Inc. Collagen-polysaccharide matrix for bone and cartilage repair
JP3033508B2 (ja) * 1997-01-20 2000-04-17 日本電気株式会社 生体内活動部位推定方法
CA2283461A1 (en) * 1997-03-14 1998-09-17 Uab Research Foundation Adenoviral vectors with modified tropism
US20020039594A1 (en) * 1997-05-13 2002-04-04 Evan C. Unger Solid porous matrices and methods of making and using the same
US6121027A (en) * 1997-08-15 2000-09-19 Surmodics, Inc. Polybifunctional reagent having a polymeric backbone and photoreactive moieties and bioactive groups
US6316522B1 (en) * 1997-08-18 2001-11-13 Scimed Life Systems, Inc. Bioresorbable hydrogel compositions for implantable prostheses
DE19737481A1 (de) * 1997-08-28 1999-03-04 Hoechst Ag Sphärische lineare Polysaccharide enthaltende Mikropartikel
US6284273B1 (en) 1998-02-24 2001-09-04 Vincent Lenaerts Cross-linked high amylose starch resistant to amylase as a matrix for the slow release of biologically active compounds
US6007833A (en) 1998-03-19 1999-12-28 Surmodics, Inc. Crosslinkable macromers bearing initiator groups
US6410044B1 (en) 1998-03-19 2002-06-25 Surmodics, Inc. Crosslinkable macromers
FR2780901B1 (fr) * 1998-07-09 2000-09-29 Coletica Particules, en particulier micro- ou nanoparticules de monosaccharides et oligosaccharides reticules, leurs procedes de preparation et compositions cosmetiques, pharmaceutiques ou alimentaires en contenant
WO2000004876A2 (en) * 1998-07-23 2000-02-03 Johns Hopkins University School Of Medicine Controlled release of bioactive substances
JP4540229B2 (ja) * 1998-07-23 2010-09-08 コオペラティ・アヴェベ・ユー・エイ 接着剤組成物
US6514534B1 (en) * 1998-08-14 2003-02-04 Incept Llc Methods for forming regional tissue adherent barriers and drug delivery systems
IT1303553B1 (it) 1998-09-01 2000-11-14 Novamont Spa Composizioni biodegradabili comprendenti amido ed esteri di cellulosa.
US6596699B2 (en) * 1998-09-22 2003-07-22 Biosurface Engineering Technologies, Inc. Nucleic acid coating compositions and methods
US6395029B1 (en) 1999-01-19 2002-05-28 The Children's Hospital Of Philadelphia Sustained delivery of polyionic bioactive agents
WO2000050050A1 (en) 1999-02-23 2000-08-31 Isis Pharmaceuticals, Inc. Multiparticulate formulation
US6716445B2 (en) * 1999-04-12 2004-04-06 Cornell Research Foundation, Inc. Hydrogel entrapping therapeutic agent and stent with coating comprising this
EP1168934B1 (en) 1999-04-12 2008-02-13 Cornell Research Foundation, Inc. Hydrogel-forming system with hydrophobic and hydrophilic components
ES2207123T3 (es) 1999-06-14 2004-05-16 Baxter International Inc. Microesferas de liberacion sostenida.
US6770740B1 (en) * 1999-07-13 2004-08-03 The Regents Of The University Of Michigan Crosslinked DNA condensate compositions and gene delivery methods
US7030097B1 (en) * 1999-07-14 2006-04-18 Cornell Research Foundation, Inc. Controlled nucleic acid delivery systems
DE60141334D1 (de) * 2000-07-17 2010-04-01 Ezaki Glico Co Biologisch abbaubare artikel aus enzymatisch hergestellter amylose
PT1313415E (pt) * 2000-08-30 2008-11-25 Univ Johns Hopkins Dispositivos para entrega intra-ocular de fármacos
EP1322337A2 (en) * 2000-09-25 2003-07-02 Board of Regents, The University of Texas System Pei : dna vector formulations for in vitro and in vivo gene delivery
SE517421C2 (sv) 2000-10-06 2002-06-04 Bioglan Ab Mikropartiklar, lämpade för parenteral administration, väsentligen bestående av stärkelse med minst 85 % amylopektin och med reducerad molekylvikt, samt framställning därav
US6748954B2 (en) * 2000-10-27 2004-06-15 The Regents Of The University Of Michigan Drug release from polymer matrices through mechanical stimulation
US6586493B1 (en) 2001-03-07 2003-07-01 Arizona Board Of Regents Arizona State University Polysaccharide-based hydrogels and pre-gel blends for the same
DE60239868D1 (de) * 2001-06-12 2011-06-09 Univ Johns Hopkins Med Reservoirvorrichtung für die intraokulare arzneimittelabgabe
US20040063654A1 (en) * 2001-11-02 2004-04-01 Davis Mark E. Methods and compositions for therapeutic use of RNA interference
AU2003218271A1 (en) * 2002-04-18 2003-11-03 Carnegie Mellon University Method of manufacturing hydroxyapatite and uses therefor in delivery of nucleic acids
US20030218130A1 (en) * 2002-05-02 2003-11-27 Ciphergen Biosystems, Inc. Biochips with surfaces coated with polysaccharide-based hydrogels
US6715445B2 (en) * 2002-05-07 2004-04-06 Rolf C. Hagen, Inc. Bird cage
DE10223310A1 (de) * 2002-05-24 2003-12-11 Biotronik Mess & Therapieg Verfahren zum Beschichten von Implantaten mit einer Polysaccharid-Lage
SE0201863D0 (en) * 2002-06-18 2002-06-18 Cepep Ab Cell penetrating peptides
US7297348B2 (en) 2002-07-19 2007-11-20 Omeros Corporation Biodegradable triblock copolymers, synthesis methods therefore, and hydrogels and biomaterials made there from
US7862831B2 (en) 2002-10-09 2011-01-04 Synthasome, Inc. Method and material for enhanced tissue-biomaterial integration
US20040062778A1 (en) 2002-09-26 2004-04-01 Adi Shefer Surface dissolution and/or bulk erosion controlled release compositions and devices
US20050143363A1 (en) * 2002-09-29 2005-06-30 Innorx, Inc. Method for subretinal administration of therapeutics including steroids; method for localizing pharmacodynamic action at the choroid of the retina; and related methods for treatment and/or prevention of retinal diseases
WO2004056311A2 (en) 2002-12-17 2004-07-08 Massachusetts Institute Of Technology Stimuli-responsive systems for controlled drug delivery
US20050025797A1 (en) 2003-04-08 2005-02-03 Xingwu Wang Medical device with low magnetic susceptibility
US8021680B2 (en) * 2003-05-02 2011-09-20 Surmodics, Inc. Controlled release bioactive agent delivery device
CN1826170B (zh) * 2003-07-18 2010-12-08 巴克斯特国际公司 通过受控相分离制备的小球形颗粒的制造方法、其用途和成分
EP1555278A1 (en) * 2004-01-15 2005-07-20 Innocore Technologies B.V. Biodegradable multi-block co-polymers
US7514530B2 (en) * 2004-04-26 2009-04-07 Centre National De La Recherche Scientifique Peptide carrier for delivering siRNA into mammalian cells
US8241655B2 (en) * 2004-05-12 2012-08-14 Surmodics, Inc. Coatings for medical articles including natural biodegradable polysaccharides
WO2005112894A1 (en) 2004-05-12 2005-12-01 Baxter International Inc. Nucleic acid microspheres, production and delivery thereof
US7740861B2 (en) 2004-06-16 2010-06-22 University Of Massachusetts Drug delivery product and methods
WO2006014484A2 (en) * 2004-07-02 2006-02-09 Surmodics, Inc. Methods and devices for the treatment of ocular conditions
CN101006107B (zh) * 2004-08-12 2011-05-18 晓温-威廉姆斯公司 碳水化合物基醇酸
AU2005309854A1 (en) * 2004-11-24 2006-06-01 Therakine Ltd. An implant for intraocular drug delivery
US20060286071A1 (en) * 2005-06-21 2006-12-21 Epstein Samuel J Therapeutic pastes for medical device coating
US8663673B2 (en) * 2005-07-29 2014-03-04 Surmodics, Inc. Devices, articles, coatings, and methods for controlled active agent release or hemocompatibility
CA2621657C (en) * 2005-09-21 2014-06-17 Surmodics, Inc. In situ occluding compositions comprising natural biodegradable polysaccharides polymerized by a redox pair
WO2007040557A1 (en) 2005-09-21 2007-04-12 Surmodics, Inc. Coatings and articles including natural biodegradable polysaccharides
WO2007059144A1 (en) * 2005-11-15 2007-05-24 Surmodics, Inc. Ultrasonic nozzles for applying two-component coatings
US8663674B2 (en) 2006-01-13 2014-03-04 Surmodics, Inc. Microparticle containing matrices for drug delivery
WO2007095152A2 (en) * 2006-02-10 2007-08-23 The Regents Of The University Of California TRANSDUCIBLE DELIVERY OF sIRNA BY dsRNA BINDING DOMAIN FUSIONS TO PTD/CPPS
CA2645324A1 (en) 2006-03-15 2007-09-27 Surmodics, Inc. Hydrophobic derivatives of natural biodegradable polysaccharides and uses thereof
JP2009542671A (ja) * 2006-06-28 2009-12-03 サーモディクス,インコーポレイティド 微粒子を含む活性剤溶出マトリックス
EP2037882B1 (en) 2006-06-28 2014-12-10 SurModics, Inc. Combination degradable and non-degradable matrices for active agent delivery
EP2056883B1 (en) * 2006-08-04 2021-09-22 Baxter International Inc. Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes
EP2068828A2 (en) * 2006-09-29 2009-06-17 SurModics, Inc. Biodegradable ocular implants and methods for treating ocular conditions
US20080154241A1 (en) 2006-12-07 2008-06-26 Burkstrand Michael J Latent stabilization of bioactive agents releasable from implantable medical articles
US8709827B2 (en) * 2007-06-28 2014-04-29 Surmodics, Inc. Polypeptide microparticles
CA2705520C (en) 2007-11-13 2016-06-28 Surmodics Pharmaceuticals, Inc. Viscous terpolymers as drug delivery platform
US20090186059A1 (en) * 2008-01-14 2009-07-23 Johnson Elizabeth E Devices and methods for elution of nucleic acid delivery complexes
EP2296630A2 (en) 2008-05-07 2011-03-23 SurModics, Inc. Delivery of nucleic acid complexes from particles
US20110159098A1 (en) * 2009-12-30 2011-06-30 Surmodics, Inc. Stabilization and delivery of nucleic acid complexes
US20110319473A1 (en) 2010-06-29 2011-12-29 Surmodics, Inc. Compositions and methods for enhancement of nucleic acid delivery
US8901092B2 (en) * 2010-12-29 2014-12-02 Surmodics, Inc. Functionalized polysaccharides for active agent delivery

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