JP2011519873A5 - - Google Patents

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Publication number
JP2011519873A5
JP2011519873A5 JP2011507792A JP2011507792A JP2011519873A5 JP 2011519873 A5 JP2011519873 A5 JP 2011519873A5 JP 2011507792 A JP2011507792 A JP 2011507792A JP 2011507792 A JP2011507792 A JP 2011507792A JP 2011519873 A5 JP2011519873 A5 JP 2011519873A5
Authority
JP
Japan
Prior art keywords
salt
chloro
trimethylpiperazine
phenylindan
trans
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011507792A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011519873A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/DK2009/050107 external-priority patent/WO2009135495A1/en
Publication of JP2011519873A publication Critical patent/JP2011519873A/ja
Publication of JP2011519873A5 publication Critical patent/JP2011519873A5/ja
Pending legal-status Critical Current

Links

JP2011507792A 2008-05-07 2009-05-07 認知欠損を治療する方法 Pending JP2011519873A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
DKPA200800647 2008-05-07
DKPA200800647 2008-05-07
DKPA200801392 2008-10-03
DKPA200801392 2008-10-03
DKPA200801519 2008-11-04
DKPA200801519 2008-11-04
PCT/DK2009/050107 WO2009135495A1 (en) 2008-05-07 2009-05-07 Method for treating cognitive deficits

Publications (2)

Publication Number Publication Date
JP2011519873A JP2011519873A (ja) 2011-07-14
JP2011519873A5 true JP2011519873A5 (https=) 2012-06-21

Family

ID=40870955

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011507792A Pending JP2011519873A (ja) 2008-05-07 2009-05-07 認知欠損を治療する方法

Country Status (15)

Country Link
US (2) US20090306092A1 (https=)
EP (1) EP2285377A1 (https=)
JP (1) JP2011519873A (https=)
KR (1) KR20110021754A (https=)
CN (1) CN102065861B (https=)
AU (1) AU2009243813B2 (https=)
BR (1) BRPI0912223A2 (https=)
CA (1) CA2722374A1 (https=)
CO (1) CO6311083A2 (https=)
EA (1) EA018927B1 (https=)
IL (1) IL209084A0 (https=)
MX (1) MX2010012037A (https=)
NZ (1) NZ589571A (https=)
WO (1) WO2009135495A1 (https=)
ZA (1) ZA201007912B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009298264A1 (en) * 2008-10-03 2010-04-08 H. Lundbeck A/S Oral formulation
JO3421B1 (ar) * 2011-06-20 2019-10-20 H Lundbeck As طريقة لإعطاء 1-((1ار.3س)-6-كلورو-3-فينيل-اندان-1-ايل)-1.2.2-ترايميثيل- بيبيرازين واملاجها لمعالجة انفصام الشخصية
PL3135656T3 (pl) 2011-06-20 2019-07-31 H. Lundbeck A/S Deuterowane 1-piperazyno-3-fenyloindany do leczenia schizofrenii
US9265458B2 (en) 2012-12-04 2016-02-23 Sync-Think, Inc. Application of smooth pursuit cognitive testing paradigms to clinical drug development
US9380976B2 (en) 2013-03-11 2016-07-05 Sync-Think, Inc. Optical neuroinformatics
EP3873885A1 (en) * 2018-10-29 2021-09-08 H. Lundbeck A/S Amorphous compounds of formula (i) and amorphous compounds of formula (i) salts
EP3891134A1 (en) 2018-12-03 2021-10-13 H. Lundbeck A/S Prodrugs of 4-((1r,3s)-6-chloro-3-phenyl-2,3-dihydro-1h-inden-1-yl)-1,2,2-trimethylpiperazine and 4-((1/r,3s)-6-chloro-3-(phenyl-d5)-2,3-dihydro-1h-inden-1-yl)-2,2-dimethy-1-(methyl-d3)piperazine

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4031216A (en) * 1974-08-12 1977-06-21 Knoll A.G. Chemische Fabriken 3-(3,4-Dialkoxy-benzyl)-3-methyl-piperazines
IE50867B1 (en) * 1980-02-29 1986-08-06 Kefalas As Indane derivatives
DE3139970A1 (de) * 1981-10-08 1983-04-28 Boehringer Mannheim Gmbh, 6800 Mannheim Neue carbonsaeurederivate, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
US5026853A (en) * 1987-04-01 1991-06-25 Janssen Pharmaceutica N.V. 4-substituted-2(or 3)aminocarbonyl-1-piperazineacetamide
US5466806A (en) * 1989-02-08 1995-11-14 Biochem Pharma Inc. Processes for preparing substituted 1,3-oxathiolanes with antiviral properties
CA2091204C (en) * 1992-03-11 1997-04-08 Ronald J. Mattson Antiischemic-piperazinyl and piperidinyl-cyclohexanes
DK55192D0 (da) * 1992-04-28 1992-04-28 Lundbeck & Co As H 1-piperazino-1,2-dihydroindenderivater
CA2132411A1 (en) * 1994-09-19 1996-03-20 Michael Trani Enzymatic esterification of long-chain racemic acids and alcohols
US6410794B1 (en) * 1994-12-16 2002-06-25 Uop Llc Process for preparation of pharmaceutically desired chiral tetralone from tetralones
US6455736B1 (en) * 1994-12-16 2002-09-24 Uop Llc Process for preparation of pharmaceutically desired sertraline and sertraline analogs
US5807897A (en) * 1996-03-01 1998-09-15 Zeneca Limited Aminotetralin derivative and compositions and method of use thereof
DE69913332T2 (de) * 1998-05-01 2004-05-27 Pfizer Products Inc., Groton Verfahren zur herstellung von enantiomeren reinem oder optisch angereicherter sertraline-tetralon durch kontinuierliche chromatographie
DE19824470A1 (de) * 1998-05-30 1999-12-02 Boehringer Ingelheim Pharma Neue Neurokininantagonisten, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
FR2786769B1 (fr) * 1998-12-04 2002-10-25 Synthelabo Derives de 2,5-diazabicyclo[2.2.1]heptane, leur preparation et leur application en therapeutique
IN187170B (https=) * 2000-01-04 2002-02-23 Sun Pharmaceutical Ind Ltd
IL162666A0 (en) * 2001-12-28 2005-11-20 Teva Pharma A stable pharmaceutical formulation of paroxetine hydrochloride and a process for preparation thereof
WO2004039322A2 (en) * 2002-10-29 2004-05-13 Miicro, Inc. Novel combination therapy for schizophrenia focused on improved cognition: 5-ht-2a/d2 blockade with adjunctive blockade of prefrontal da reuptake
BRPI0413595B8 (pt) * 2003-08-18 2021-05-25 H Lundbeck As sal de malonato, composição farmacêutica, uso de um sal de malonato, e, método de fabricação de um composto
TW200640891A (en) * 2005-02-16 2006-12-01 Lundbeck & Co As H Tartrate and malate salts of a pharmarceutical compound
US20080269248A1 (en) * 2005-02-16 2008-10-30 H. Lundbeck A/S Tartrate and Malate Salts of Trans-1-((1R,3S)-6-Chloro-3-Phenylindan-1-Yl)-3,3-Dimethylpiperazine
TWI376373B (en) * 2005-02-16 2012-11-11 Lundbeck & Co As H Crystalline base of a pharmaceutical compound
TW200817400A (en) * 2006-05-30 2008-04-16 Elbion Ag Pyrido [3,2-e] pyrazines, their use as inhibitors of phosphodiesterase 10, and processes for preparing them
AU2009298264A1 (en) * 2008-10-03 2010-04-08 H. Lundbeck A/S Oral formulation

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