JP2011517969A5 - - Google Patents
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- Publication number
- JP2011517969A5 JP2011517969A5 JP2011500894A JP2011500894A JP2011517969A5 JP 2011517969 A5 JP2011517969 A5 JP 2011517969A5 JP 2011500894 A JP2011500894 A JP 2011500894A JP 2011500894 A JP2011500894 A JP 2011500894A JP 2011517969 A5 JP2011517969 A5 JP 2011517969A5
- Authority
- JP
- Japan
- Prior art keywords
- layer
- coating
- device body
- poly
- lactic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000011248 coating agent Substances 0.000 claims description 18
- 238000000576 coating method Methods 0.000 claims description 18
- 239000012867 bioactive agent Substances 0.000 claims description 10
- 238000000034 method Methods 0.000 claims 7
- 229920000118 poly(D-lactic acid) Polymers 0.000 claims 5
- 229920001432 poly(L-lactide) Polymers 0.000 claims 5
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 229920000642 polymer Polymers 0.000 description 14
- 239000000463 material Substances 0.000 description 11
- 239000000758 substrate Substances 0.000 description 4
- 239000000203 mixture Substances 0.000 description 3
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000028993 immune response Effects 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 229920002126 Acrylic acid copolymer Polymers 0.000 description 1
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 description 1
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 description 1
- 229920002873 Polyethylenimine Polymers 0.000 description 1
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical compound [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- 229920000249 biocompatible polymer Polymers 0.000 description 1
- 238000006065 biodegradation reaction Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 239000007857 degradation product Substances 0.000 description 1
- 238000010828 elution Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 229920003145 methacrylic acid copolymer Polymers 0.000 description 1
- 229940117841 methacrylic acid copolymer Drugs 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 229920000052 poly(p-xylylene) Polymers 0.000 description 1
- 229910000077 silane Inorganic materials 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/052,452 US8377116B2 (en) | 2008-03-20 | 2008-03-20 | Implantable medical device coatings with improved mechanical stability |
| US12/052,452 | 2008-03-20 | ||
| PCT/US2009/037375 WO2009117398A2 (en) | 2008-03-20 | 2009-03-17 | Implantable medical device coatings with improved mechanical stability |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011517969A JP2011517969A (ja) | 2011-06-23 |
| JP2011517969A5 true JP2011517969A5 (https=) | 2014-01-16 |
| JP5500397B2 JP5500397B2 (ja) | 2014-05-21 |
Family
ID=40637707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011500894A Active JP5500397B2 (ja) | 2008-03-20 | 2009-03-17 | 機械的安定性が改善した埋め込み型医療デバイスコーティング |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US8377116B2 (https=) |
| EP (1) | EP2268329B1 (https=) |
| JP (1) | JP5500397B2 (https=) |
| WO (1) | WO2009117398A2 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102292053A (zh) | 2008-09-29 | 2011-12-21 | 卡迪尔克阀门技术公司 | 心脏瓣膜 |
| CA2739275C (en) | 2008-10-01 | 2017-01-17 | Impala, Inc. | Delivery system for vascular implant |
| AU2010236288A1 (en) | 2009-04-15 | 2011-10-20 | Cardiaq Valve Technologies, Inc. | Vascular implant and delivery system |
| US8579964B2 (en) | 2010-05-05 | 2013-11-12 | Neovasc Inc. | Transcatheter mitral valve prosthesis |
| US9308087B2 (en) | 2011-04-28 | 2016-04-12 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
| US9554897B2 (en) | 2011-04-28 | 2017-01-31 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
| KR101360106B1 (ko) * | 2012-04-18 | 2014-02-12 | 한국과학기술연구원 | 표면 개질된 세라믹 입자 및 스테레오 콤플렉스를 이루는 생분해성 고분자를 포함하는 생체 이식물, 이의 염증 억제 및 기계적 물성 향상용으로서의 용도 및 그 제조 방법 |
| US9345573B2 (en) | 2012-05-30 | 2016-05-24 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
| US10583002B2 (en) | 2013-03-11 | 2020-03-10 | Neovasc Tiara Inc. | Prosthetic valve with anti-pivoting mechanism |
| US9681951B2 (en) | 2013-03-14 | 2017-06-20 | Edwards Lifesciences Cardiaq Llc | Prosthesis with outer skirt and anchors |
| US9572665B2 (en) | 2013-04-04 | 2017-02-21 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
| CN108338989B (zh) * | 2017-08-08 | 2021-12-17 | 新昕医药科技（上海）有限公司 | 冠脉药物洗脱支架的复合抗再狭窄药物及其控释系统 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04226125A (ja) | 1990-06-23 | 1992-08-14 | Boehringer Ingelheim Kg | ポリ−ｄ，ｌ−ラクチドの製造方法及び活性物質の担体としてのそれらの使用 |
| US5346966A (en) * | 1991-12-31 | 1994-09-13 | E. I. Du Pont De Nemours And Company | L,d-polylactide copolymers with controlled morphology |
| US5338822A (en) * | 1992-10-02 | 1994-08-16 | Cargill, Incorporated | Melt-stable lactide polymer composition and process for manufacture thereof |
| CN1261084C (zh) * | 2000-03-13 | 2006-06-28 | 伊垣敬二 | 血管支撑架用线材及用此线材的血管支撑架 |
| US6939376B2 (en) * | 2001-11-05 | 2005-09-06 | Sun Biomedical, Ltd. | Drug-delivery endovascular stent and method for treating restenosis |
| CA2503949C (en) | 2002-10-29 | 2012-10-23 | Toray Industries, Inc. | Embolization material |
| US20050112170A1 (en) * | 2003-11-20 | 2005-05-26 | Hossainy Syed F. | Coatings for implantable devices comprising polymers of lactic acid and methods for fabricating the same |
| US8110211B2 (en) * | 2004-09-22 | 2012-02-07 | Advanced Cardiovascular Systems, Inc. | Medicated coatings for implantable medical devices including polyacrylates |
| US8778375B2 (en) * | 2005-04-29 | 2014-07-15 | Advanced Cardiovascular Systems, Inc. | Amorphous poly(D,L-lactide) coating |
| US20070043434A1 (en) * | 2005-08-18 | 2007-02-22 | David Meerkin | Biodegradable endovascular stent using stereocomplexation of polymers |
| JP5102200B2 (ja) * | 2006-03-30 | 2012-12-19 | テルモ株式会社 | 生体内留置物 |
| WO2007116646A1 (ja) | 2006-04-04 | 2007-10-18 | Terumo Kabushiki Kaisha | 生体内留置物 |
| US7862830B2 (en) * | 2006-07-13 | 2011-01-04 | Abbott Cardiovascular Systems Inc. | Stereocomplex-forming composition and implantable medical device comprising same |
| US20080020014A1 (en) * | 2006-07-19 | 2008-01-24 | Paul Consigny | Implantable devices containing nuclear receptor ligands for the treatment of vascular and related disorders |
-
2008
- 2008-03-20 US US12/052,452 patent/US8377116B2/en not_active Expired - Fee Related
-
2009
- 2009-03-17 EP EP09722969.4A patent/EP2268329B1/en not_active Not-in-force
- 2009-03-17 WO PCT/US2009/037375 patent/WO2009117398A2/en not_active Ceased
- 2009-03-17 JP JP2011500894A patent/JP5500397B2/ja active Active
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