JP2011517320A5 - - Google Patents

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Publication number
JP2011517320A5
JP2011517320A5 JP2010549831A JP2010549831A JP2011517320A5 JP 2011517320 A5 JP2011517320 A5 JP 2011517320A5 JP 2010549831 A JP2010549831 A JP 2010549831A JP 2010549831 A JP2010549831 A JP 2010549831A JP 2011517320 A5 JP2011517320 A5 JP 2011517320A5
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JP
Japan
Prior art keywords
mmp
binding protein
human
binding
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010549831A
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English (en)
Japanese (ja)
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JP2011517320A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2009/035926 external-priority patent/WO2009111508A2/en
Publication of JP2011517320A publication Critical patent/JP2011517320A/ja
Publication of JP2011517320A5 publication Critical patent/JP2011517320A5/ja
Pending legal-status Critical Current

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JP2010549831A 2008-03-03 2009-03-03 メタロプロテアーゼ9結合タンパク質およびメタロプロテアーゼ2結合タンパク質 Pending JP2011517320A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3306808P 2008-03-03 2008-03-03
US61/033,068 2008-03-03
PCT/US2009/035926 WO2009111508A2 (en) 2008-03-03 2009-03-03 Metalloproteinase 9 and metalloproteinase 2 binding proteins

Publications (2)

Publication Number Publication Date
JP2011517320A JP2011517320A (ja) 2011-06-02
JP2011517320A5 true JP2011517320A5 (enExample) 2012-04-26

Family

ID=41056616

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010549831A Pending JP2011517320A (ja) 2008-03-03 2009-03-03 メタロプロテアーゼ9結合タンパク質およびメタロプロテアーゼ2結合タンパク質

Country Status (6)

Country Link
US (2) US8013125B2 (enExample)
EP (1) EP2262840A4 (enExample)
JP (1) JP2011517320A (enExample)
AU (1) AU2009221916A1 (enExample)
CA (1) CA2717803A1 (enExample)
WO (1) WO2009111508A2 (enExample)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006332713B2 (en) 2005-12-30 2013-01-17 Takeda Pharmaceutical Company Limited Metalloproteinase binding proteins
EP2231186A4 (en) 2007-12-17 2012-08-08 Dyax Corp COMPOSITIONS AND METHODS FOR TREATING OSTEOLYTIC DISORDERS COMPRISING MMP-14 BINDING PROTEINS
WO2009079581A1 (en) 2007-12-17 2009-06-25 Dyax Corp. Evaluating mmp expression in patient stratification and other therapeutic, diagnostic and prognostic methods for cancer
CA2717803A1 (en) 2008-03-03 2009-09-11 Dyax Corp. Metalloproteinase 9 and metalloproteinase 2 binding proteins
US8008445B2 (en) 2008-03-03 2011-08-30 Dyax Corp. Metalloproteinase 9 binding proteins
US20110135573A1 (en) * 2009-09-03 2011-06-09 Dyax Corp. Metalloproteinase 9 and metalloproteinase 2 binding proteins
US8530453B2 (en) * 2009-09-28 2013-09-10 Aquilus Pharmaceuticals, Inc. Compounds and methods for the treatment of pain and other diseases
CA2787311C (en) * 2010-01-27 2017-08-15 Yeda Research And Development Co. Ltd. Antibodies that inhibit metalloproteins
AU2011267869A1 (en) 2010-06-14 2013-01-10 Vaccinex, Inc. Anti-VEGF antibodies and uses thereof
KR101900435B1 (ko) 2010-06-16 2018-09-20 트렐리스 바이오싸이언스 인코포레이티드 인간 사이토메갈로바이러스 gB 단백질에 대한 고친화도 인간 항체
PE20131376A1 (es) 2010-08-27 2013-11-25 Gilead Biologics Inc Anticuerpos para metaloproteinasa-9 de matriz
AU2011318567B2 (en) * 2010-10-19 2017-02-09 Mayo Foundation For Medical Education And Research Human antibodies and diagnostic and therapeutic uses thereof for the treatment of neurological disease
US20140199324A1 (en) * 2011-03-24 2014-07-17 Daniel T. Dransfield Evaluating protein expression in patient stratification and other therapeutic, diagnostic and prognostic methods for cancer
US10314909B2 (en) 2011-10-21 2019-06-11 Dyax Corp. Combination therapy comprising an MMP-14 binding protein
EP2819697A4 (en) 2012-02-29 2016-03-09 Gilead Biologics Inc ANTIBODIES AGAINST METALLOPROTEINASE 9 OF MATRIX
US9550836B2 (en) * 2012-02-29 2017-01-24 Gilead Biologics, Inc. Method of detecting human matrix metalloproteinase 9 using antibodies
US9603927B2 (en) * 2014-02-28 2017-03-28 Janssen Biotech, Inc. Combination therapies with anti-CD38 antibodies
US9732154B2 (en) 2014-02-28 2017-08-15 Janssen Biotech, Inc. Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia
EP2985296A1 (en) 2014-08-13 2016-02-17 Calypso Biotech SA Antibodies specific for MMP9
EP2985295A1 (en) 2014-08-13 2016-02-17 Calypso Biotech SA Antibodies specific for MMP9
BR112017004614A2 (pt) 2014-09-09 2018-02-27 Janssen Biotech, Inc. terapias de combinação com anticorpos anti-cd38
EA202092609A1 (ru) 2014-12-04 2021-10-29 Янссен Байотек, Инк. Антитела к cd38 для лечения острого миелолейкоза
CN108136218B (zh) 2015-05-20 2022-12-13 詹森生物科技公司 用于治疗轻链淀粉样变性及其它cd38阳性血液恶性肿瘤的抗cd38抗体
NZ777133A (en) 2015-06-22 2025-05-02 Janssen Biotech Inc Combination therapies for heme malignancies with anti-cd38 antibodies and survivin inhibitors
US20170044265A1 (en) 2015-06-24 2017-02-16 Janssen Biotech, Inc. Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38
RS61651B1 (sr) 2015-11-03 2021-04-29 Janssen Biotech Inc Potkožne formulacije anti-cd38 antitela i njihova upotreba
US10781261B2 (en) 2015-11-03 2020-09-22 Janssen Biotech, Inc. Subcutaneous formulations of anti-CD38 antibodies and their uses
CA3029074A1 (en) 2016-06-22 2018-01-25 William Warren HARLESS Cancer treatment and metastasis inhibition using an anti-cancer stem cell agent in combination with a neu1 sialidase inhibitor or a cytokine inhibitor after primary cancer treatment
CN108456250B (zh) * 2017-02-17 2025-11-28 恺兴生命科技(上海)有限公司 靶向il-13ra2的抗体及其应用
WO2018169785A2 (en) * 2017-03-13 2018-09-20 The Government Of The United States Of America As Represented By The Secretary Of The Army Therapeutic antibodies to marburg virus
JP2021502961A (ja) 2017-10-31 2021-02-04 ヤンセン バイオテツク,インコーポレーテツド 高リスク多発性骨髄腫の治療方法
WO2019118831A1 (en) * 2017-12-15 2019-06-20 Bomi, Llc Anti-cannabidiol antibody and uses thereof
CN110642948B (zh) * 2019-10-09 2021-06-29 达石药业(广东)有限公司 B7-h3纳米抗体、其制备方法及用途
UY40783A (es) 2023-06-12 2024-12-31 Amgen Inc Proteínas de unión a agonistas del receptor beta de linfotoxina
WO2025076280A1 (en) 2023-10-05 2025-04-10 Ashibio, Inc. Methods and compositions for treating mmp-9 mediated disorders

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9809764D0 (en) * 1998-05-07 1998-07-08 Isis Innovation MMP-9 Gene polymorphisms
CA2379373A1 (en) 1999-07-13 2001-01-18 University Of Southern California Novel method and composition for inhibition of angiogenesis using antagonists based on mmp-9 and .beta.1 integrins
WO2001026671A1 (en) * 1999-10-12 2001-04-19 Smithkline Beecham Corporation Methods of treatment using dual matrix-metalloproteinase-2 and matrix metalloproteinase-9 inhibitors
US6573096B1 (en) 2000-04-01 2003-06-03 The Research Foundation At State University Of New York Compositions and methods for inhibition of cancer invasion and angiogenesis
WO2001090326A2 (en) * 2000-05-22 2001-11-29 Pharmacia & Upjohn Company Novel matrix metalloproteinases
AR028606A1 (es) 2000-05-24 2003-05-14 Smithkline Beecham Corp Nuevos inhibidores de mmp-2/mmp-9
IL153567A0 (en) * 2000-06-29 2003-07-06 Abbott Lab Dual specificity antibodies and methods of making and using
US20070258987A1 (en) 2000-11-28 2007-11-08 Seattle Genetics, Inc. Recombinant Anti-Cd30 Antibodies and Uses Thereof
WO2002066057A2 (en) * 2001-02-23 2002-08-29 Biophage Inc. Methods and compositions for preventing and treating neutrophil-mediated diseases
ATE439588T1 (de) 2001-05-04 2009-08-15 Biosite Inc Diagnostische marker für akute herzerkrankungen und verfahren des gebrauchs
AU2003274059A1 (en) * 2002-10-23 2004-05-13 F. Hoffmann-La Roche Ag Combination of a trioxopyrimidine compound inhibitor and an anti-tumor agent, and uses thereof
DK2330132T3 (da) * 2003-04-04 2013-11-04 Yeda Res & Dev Antistoffer mod MMP2 eller MMP9 og farmaceutiske sammensætninger deraf til hæmning af deres metalloproteinaktivitet
US7435800B2 (en) 2003-05-23 2008-10-14 Chi-Mei Medical Center Antibodies to interleukin-20 and method for inhibiting interleukin-20 induced cell proliferation
US20050118632A1 (en) * 2003-11-06 2005-06-02 Jian Chen Polynucleotides and polypeptides encoding a novel metalloprotease, Protease-40b
CN100497324C (zh) * 2004-05-27 2009-06-10 武汉科艾硒医药科技发展有限公司 具有抗纤维化及抑制明胶酶活性的化合物及其应用
WO2006036928A2 (en) * 2004-09-27 2006-04-06 Wayne State University Inhibitors of matrix metalloproteinases to treat neurological disorders
WO2006084109A2 (en) * 2005-02-02 2006-08-10 Pro Term, Inc. Salivary protease assays for identifying increased risk of preterm delivery induced by premature rupture of fetal membranes
DE102005015040A1 (de) * 2005-03-31 2006-10-05 Sanofi-Aventis Deutschland Gmbh Substituierte Tetrahydroisochinoline als MMP-Inhibitoren, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament
EP1931632A4 (en) 2005-08-18 2011-05-11 Microbia Inc USEFUL INDOOR CONNECTIONS
US8092819B2 (en) 2006-01-27 2012-01-10 Cook Medical Technologies LLC. Implantable medical device coated with a bioactive agent
WO2007149948A2 (en) * 2006-06-20 2007-12-27 The Gov. Of The Usa As Represented By The Secretary Of The Department Of Health And Human Services Compositions and methods for diagnosis and treatment of tumors
EP2155691B1 (en) * 2007-02-23 2016-01-13 Yeda Research and Development Co. Ltd. Antibodies and pharmaceutical compositions containing same useful for inhibiting activity of metalloproteins
EP2231186A4 (en) 2007-12-17 2012-08-08 Dyax Corp COMPOSITIONS AND METHODS FOR TREATING OSTEOLYTIC DISORDERS COMPRISING MMP-14 BINDING PROTEINS
WO2009079581A1 (en) 2007-12-17 2009-06-25 Dyax Corp. Evaluating mmp expression in patient stratification and other therapeutic, diagnostic and prognostic methods for cancer
CA2717803A1 (en) 2008-03-03 2009-09-11 Dyax Corp. Metalloproteinase 9 and metalloproteinase 2 binding proteins
US8008445B2 (en) 2008-03-03 2011-08-30 Dyax Corp. Metalloproteinase 9 binding proteins
WO2010045388A2 (en) 2008-10-14 2010-04-22 Dyax Corp. Use of mmp-9 and mmp-12 binding proteins for the treatment and prevention of systemic sclerosis
US20110262396A1 (en) 2008-10-22 2011-10-27 Dyax Corp. Combination treatments comprising protease binding proteins for inflammatory disorders
US20110135573A1 (en) 2009-09-03 2011-06-09 Dyax Corp. Metalloproteinase 9 and metalloproteinase 2 binding proteins

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