JP2011517320A5 - - Google Patents
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- Publication number
- JP2011517320A5 JP2011517320A5 JP2010549831A JP2010549831A JP2011517320A5 JP 2011517320 A5 JP2011517320 A5 JP 2011517320A5 JP 2010549831 A JP2010549831 A JP 2010549831A JP 2010549831 A JP2010549831 A JP 2010549831A JP 2011517320 A5 JP2011517320 A5 JP 2011517320A5
- Authority
- JP
- Japan
- Prior art keywords
- mmp
- binding protein
- human
- binding
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3306808P | 2008-03-03 | 2008-03-03 | |
| US61/033,068 | 2008-03-03 | ||
| PCT/US2009/035926 WO2009111508A2 (en) | 2008-03-03 | 2009-03-03 | Metalloproteinase 9 and metalloproteinase 2 binding proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011517320A JP2011517320A (ja) | 2011-06-02 |
| JP2011517320A5 true JP2011517320A5 (enExample) | 2012-04-26 |
Family
ID=41056616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010549831A Pending JP2011517320A (ja) | 2008-03-03 | 2009-03-03 | メタロプロテアーゼ９結合タンパク質およびメタロプロテアーゼ２結合タンパク質 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8013125B2 (enExample) |
| EP (1) | EP2262840A4 (enExample) |
| JP (1) | JP2011517320A (enExample) |
| AU (1) | AU2009221916A1 (enExample) |
| CA (1) | CA2717803A1 (enExample) |
| WO (1) | WO2009111508A2 (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7745587B2 (en) | 2005-12-30 | 2010-06-29 | Dyax Corp. | Antibodies that bind MMP-14 |
| CA2707637A1 (en) | 2007-12-17 | 2009-06-25 | Dyax Corp. | Compositions and methods for treating osteolytic disorders comprising mmp-14 binding proteins |
| WO2009079581A1 (en) * | 2007-12-17 | 2009-06-25 | Dyax Corp. | Evaluating mmp expression in patient stratification and other therapeutic, diagnostic and prognostic methods for cancer |
| US8013125B2 (en) | 2008-03-03 | 2011-09-06 | Dyax Corp. | Metalloproteinase 9 and metalloproteinase 2 binding proteins |
| JP2011517662A (ja) | 2008-03-03 | 2011-06-16 | ダイアックス コーポレーション | メタロプロテアーゼ９結合タンパク質 |
| WO2011028883A2 (en) * | 2009-09-03 | 2011-03-10 | Dyax Corp. | Metalloproteinase 9 and metalloproteinase 2 binding proteins |
| US8530453B2 (en) * | 2009-09-28 | 2013-09-10 | Aquilus Pharmaceuticals, Inc. | Compounds and methods for the treatment of pain and other diseases |
| CN102822202B (zh) | 2010-01-27 | 2015-07-22 | 耶达研究及发展有限公司 | 抑制金属蛋白的抗体 |
| CA2802376A1 (en) | 2010-06-14 | 2011-12-22 | Vaccinex, Inc. | Anti-vegf antibodies and uses thereof |
| CA2839420C (en) | 2010-06-16 | 2023-06-13 | Lawrence M. Kauvar | High affinity human antibodies to human cytomegalovirus (cmv) gb protein |
| WO2012027721A2 (en) | 2010-08-27 | 2012-03-01 | Gilead Biologics, Inc | Antibodies to matrix metalloproteinase 9 |
| WO2012054077A2 (en) * | 2010-10-19 | 2012-04-26 | Mayo Foundation For Medical Education And Research | Human antibodies and diagnostic and therapeutic uses thereof for the treatment of neurological disease |
| WO2012129517A2 (en) * | 2011-03-24 | 2012-09-27 | Dyax Corp. | Evaluating protein expression in patient stratification and other therapeutic, diagnostic and prognostic methods for cancer |
| US10314909B2 (en) | 2011-10-21 | 2019-06-11 | Dyax Corp. | Combination therapy comprising an MMP-14 binding protein |
| SG11201405305PA (en) | 2012-02-29 | 2014-09-26 | Gilead Biologics Inc | Antibodies to matrix metalloproteinase 9 |
| MD20140108A2 (ro) | 2012-02-29 | 2015-03-31 | Gilead Biologics, Inc. | Anticorpi împotriva metaloproteinazei 9 matriciale |
| US9732154B2 (en) | 2014-02-28 | 2017-08-15 | Janssen Biotech, Inc. | Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia |
| US9603927B2 (en) | 2014-02-28 | 2017-03-28 | Janssen Biotech, Inc. | Combination therapies with anti-CD38 antibodies |
| EP2985295A1 (en) | 2014-08-13 | 2016-02-17 | Calypso Biotech SA | Antibodies specific for MMP9 |
| EP2985296A1 (en) | 2014-08-13 | 2016-02-17 | Calypso Biotech SA | Antibodies specific for MMP9 |
| WO2016040294A2 (en) | 2014-09-09 | 2016-03-17 | Janssen Biotech, Inc. | Combination therapies with anti-cd38 antibodies |
| PE20171094A1 (es) | 2014-12-04 | 2017-08-07 | Janssen Biotech Inc | Anticuerpos anti-cd38 para el tratamiento de la leucemia linfoblastica aguda |
| CR20170526A (es) | 2015-05-20 | 2018-04-03 | Janssen Biotech Inc | ANTICUERPOS ANTI-CD38 PARA EL TRATAMIENTO DE AMILOIDOSIS DE CADENA LIGERA y OTRAS ENFERMEDADES MALIGNAS HEMATOLÓGICAS POSITIVAS PARA CD38 |
| CN107708734B (zh) | 2015-06-22 | 2022-01-11 | 詹森生物科技公司 | 用抗cd38抗体和生存素抑制剂联合治疗血红素恶性肿瘤 |
| US20170044265A1 (en) | 2015-06-24 | 2017-02-16 | Janssen Biotech, Inc. | Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38 |
| US10781261B2 (en) | 2015-11-03 | 2020-09-22 | Janssen Biotech, Inc. | Subcutaneous formulations of anti-CD38 antibodies and their uses |
| JP7027321B2 (ja) | 2015-11-03 | 2022-03-01 | ヤンセン バイオテツク，インコーポレーテツド | 抗ｃｄ３８抗体の皮下製剤及びその使用 |
| US20200306283A1 (en) | 2016-06-22 | 2020-10-01 | William Warren HARLESS | Cancer treatment and metastasis inhibition using an anti-cancer stem cell agent in combination with a neu1 sialidase inhibitor or a cytokine inhibitor after primary cancer treatment |
| WO2018002181A1 (en) | 2016-06-28 | 2018-01-04 | Umc Utrecht Holding B.V. | TREATMENT OF IgE-MEDIATED DISEASES WITH ANTIBODIES THAT SPECIFICALLY BIND CD38 |
| CN108456250B (zh) * | 2017-02-17 | 2025-11-28 | 恺兴生命科技(上海)有限公司 | 靶向il-13ra2的抗体及其应用 |
| WO2018169785A2 (en) * | 2017-03-13 | 2018-09-20 | The Government Of The United States Of America As Represented By The Secretary Of The Army | Therapeutic antibodies to marburg virus |
| US11618787B2 (en) | 2017-10-31 | 2023-04-04 | Janssen Biotech, Inc. | Methods of treating high risk multiple myeloma |
| EP3724657A4 (en) | 2017-12-15 | 2021-12-29 | Bomi, Llc | Anti-cannabidiol antibody and uses thereof |
| CN110642948B (zh) * | 2019-10-09 | 2021-06-29 | 达石药业(广东)有限公司 | B7-h3纳米抗体、其制备方法及用途 |
| CN121399157A (zh) | 2023-06-12 | 2026-01-23 | 美国安进公司 | 淋巴毒素β受体激动剂结合蛋白 |
| EP4788430A1 (en) | 2023-10-05 | 2026-08-12 | Ashibio, Inc. | Methods and compositions for treating mmp-9 mediated disorders |
| WO2026076260A1 (en) | 2024-10-03 | 2026-04-09 | Ashibio, Inc. | Methods and compositions for mmp-9 inhibition for use with non-genetic heterotopic ossification disorders |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9809764D0 (en) * | 1998-05-07 | 1998-07-08 | Isis Innovation | MMP-9 Gene polymorphisms |
| ES2327812T3 (es) | 1999-07-13 | 2009-11-04 | University Of Southern California | Nuevos metodos y composiciones para inhibir la angiogenesis utilizando bases antagonistas de mmp-9 y/o integrinas beta-1. |
| WO2001026671A1 (en) * | 1999-10-12 | 2001-04-19 | Smithkline Beecham Corporation | Methods of treatment using dual matrix-metalloproteinase-2 and matrix metalloproteinase-9 inhibitors |
| US6573096B1 (en) * | 2000-04-01 | 2003-06-03 | The Research Foundation At State University Of New York | Compositions and methods for inhibition of cancer invasion and angiogenesis |
| WO2001090326A2 (en) * | 2000-05-22 | 2001-11-29 | Pharmacia & Upjohn Company | Novel matrix metalloproteinases |
| AR028606A1 (es) | 2000-05-24 | 2003-05-14 | Smithkline Beecham Corp | Nuevos inhibidores de mmp-2/mmp-9 |
| PE20020132A1 (es) * | 2000-06-29 | 2002-03-04 | Abbott Lab | Anticuerpos de especificidad doble y metodos para la elaboracion y el uso de los mismos |
| US20070258987A1 (en) | 2000-11-28 | 2007-11-08 | Seattle Genetics, Inc. | Recombinant Anti-Cd30 Antibodies and Uses Thereof |
| AU2002235692A1 (en) * | 2001-02-23 | 2002-09-04 | Biophage Inc. | Methods and compositions for preventing and treating neutrophil-mediated diseases |
| EP1322957B1 (en) | 2001-05-04 | 2009-08-12 | Biosite Incorporated | Diagnostic markers of acute coronary syndromes and methods of use thereof |
| AU2003274059A1 (en) * | 2002-10-23 | 2004-05-13 | F. Hoffmann-La Roche Ag | Combination of a trioxopyrimidine compound inhibitor and an anti-tumor agent, and uses thereof |
| ATE517926T1 (de) * | 2003-04-04 | 2011-08-15 | Yeda Res & Dev | Antikörper zur hemmung der aktivität von mmp-2 und mmp-9 |
| US7435800B2 (en) | 2003-05-23 | 2008-10-14 | Chi-Mei Medical Center | Antibodies to interleukin-20 and method for inhibiting interleukin-20 induced cell proliferation |
| US20050118632A1 (en) | 2003-11-06 | 2005-06-02 | Jian Chen | Polynucleotides and polypeptides encoding a novel metalloprotease, Protease-40b |
| CN100497324C (zh) * | 2004-05-27 | 2009-06-10 | 武汉科艾硒医药科技发展有限公司 | 具有抗纤维化及抑制明胶酶活性的化合物及其应用 |
| WO2006036928A2 (en) | 2004-09-27 | 2006-04-06 | Wayne State University | Inhibitors of matrix metalloproteinases to treat neurological disorders |
| US20080254490A1 (en) | 2005-02-02 | 2008-10-16 | Ramkumar Menon | Salivary Protease Assays for Identifying Increased Risk of Preterm Delivery Induced by Premature Rupture of Fetal Membranes |
| DE102005015040A1 (de) | 2005-03-31 | 2006-10-05 | Sanofi-Aventis Deutschland Gmbh | Substituierte Tetrahydroisochinoline als MMP-Inhibitoren, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament |
| US20070203209A1 (en) | 2005-08-18 | 2007-08-30 | Wilmin Bartolini | Useful indole compounds |
| US8092819B2 (en) | 2006-01-27 | 2012-01-10 | Cook Medical Technologies LLC. | Implantable medical device coated with a bioactive agent |
| WO2007149948A2 (en) | 2006-06-20 | 2007-12-27 | The Gov. Of The Usa As Represented By The Secretary Of The Department Of Health And Human Services | Compositions and methods for diagnosis and treatment of tumors |
| EP2155691B1 (en) * | 2007-02-23 | 2016-01-13 | Yeda Research and Development Co. Ltd. | Antibodies and pharmaceutical compositions containing same useful for inhibiting activity of metalloproteins |
| WO2009079581A1 (en) | 2007-12-17 | 2009-06-25 | Dyax Corp. | Evaluating mmp expression in patient stratification and other therapeutic, diagnostic and prognostic methods for cancer |
| CA2707637A1 (en) | 2007-12-17 | 2009-06-25 | Dyax Corp. | Compositions and methods for treating osteolytic disorders comprising mmp-14 binding proteins |
| US8013125B2 (en) | 2008-03-03 | 2011-09-06 | Dyax Corp. | Metalloproteinase 9 and metalloproteinase 2 binding proteins |
| JP2011517662A (ja) | 2008-03-03 | 2011-06-16 | ダイアックス コーポレーション | メタロプロテアーゼ９結合タンパク質 |
| WO2010045388A2 (en) | 2008-10-14 | 2010-04-22 | Dyax Corp. | Use of mmp-9 and mmp-12 binding proteins for the treatment and prevention of systemic sclerosis |
| WO2010048432A1 (en) | 2008-10-22 | 2010-04-29 | Dyax Corp. | Combination treatments comprising protease binding proteins for inflammatory disorders |
| WO2011028883A2 (en) | 2009-09-03 | 2011-03-10 | Dyax Corp. | Metalloproteinase 9 and metalloproteinase 2 binding proteins |
-
2009
- 2009-03-03 US US12/397,285 patent/US8013125B2/en active Active
- 2009-03-03 WO PCT/US2009/035926 patent/WO2009111508A2/en not_active Ceased
- 2009-03-03 AU AU2009221916A patent/AU2009221916A1/en not_active Abandoned
- 2009-03-03 EP EP09717527A patent/EP2262840A4/en not_active Withdrawn
- 2009-03-03 CA CA2717803A patent/CA2717803A1/en not_active Abandoned
- 2009-03-03 JP JP2010549831A patent/JP2011517320A/ja active Pending
-
2011
- 2011-08-01 US US13/195,710 patent/US20110300157A1/en not_active Abandoned
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