JP2011511085A - グルココルチコイド受容体、ＡＰ−１、および／またはＮＦ−κＢ活性の縮合ヘテロアリール修飾因子並びにその使用 - Google Patents

グルココルチコイド受容体、ＡＰ−１、および／またはＮＦ−κＢ活性の縮合ヘテロアリール修飾因子並びにその使用 Download PDF

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JP2011511085A
JP2011511085A JP2010545976A JP2010545976A JP2011511085A JP 2011511085 A JP2011511085 A JP 2011511085A JP 2010545976 A JP2010545976 A JP 2010545976A JP 2010545976 A JP2010545976 A JP 2010545976A JP 2011511085 A JP2011511085 A JP 2011511085A
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alkyl
aryl
substituted
mmol
halo
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JP2011511085A5 (enExample
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ジンウ・デュアン
デイビッド・エス・ウェインステイン
ビン・ジアン
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Bristol Myers Squibb Co
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    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C07D491/147—Ortho-condensed systems the condensed system containing one ring with oxygen as ring hetero atom and two rings with nitrogen as ring hetero atom
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JP2010545976A 2008-02-07 2009-02-05 グルココルチコイド受容体、ＡＰ−１、および／またはＮＦ−κＢ活性の縮合ヘテロアリール修飾因子並びにその使用 Withdrawn JP2011511085A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2681608P 2008-02-07 2008-02-07
PCT/US2009/033134 WO2009100171A1 (en) 2008-02-07 2009-02-05 Fused heteroaryl modulators of glucocorticoid receptor, ap-1, and/or nf-kb activity and use thereof

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JP2011511085A true JP2011511085A (ja) 2011-04-07
JP2011511085A5 JP2011511085A5 (enExample) 2012-03-15

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JP2010545976A Withdrawn JP2011511085A (ja) 2008-02-07 2009-02-05 グルココルチコイド受容体、ＡＰ−１、および／またはＮＦ−κＢ活性の縮合ヘテロアリール修飾因子並びにその使用

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Country Link
US (1) US8304539B2 (enExample)
EP (1) EP2247597A1 (enExample)
JP (1) JP2011511085A (enExample)
CN (1) CN101990541A (enExample)
WO (1) WO2009100171A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112013004322A2 (pt) * 2010-08-27 2016-06-21 Corcept Therapeutics Inc moduladores de azadecalin fundidos com piridil-aminas
WO2015077537A1 (en) * 2013-11-25 2015-05-28 Corcept Therapeutics, Inc. Heteroaryl-ether fused azadecalin glucocorticoid receptor modulators
ES2943542T3 (es) * 2013-11-25 2023-06-14 Corcept Therapeutics Inc Moduladores del receptor de glucocorticoides de azadecalina condensada con octahidro
CN108546246A (zh) * 2018-07-10 2018-09-18 湖南华腾制药有限公司 一种双吡啶基甲醇的制备方法
CN113373466B (zh) * 2021-06-19 2023-07-21 安徽科技学院 一种β-乙酰氨基羰基化合物的电化学合成方法
AR127618A1 (es) 2021-11-29 2024-02-14 Bayer Ag Dihidropiranopiridinas sustituidas, sales o n-óxidos de las mismas y su uso como sustancias herbicidamente activas
WO2025057723A1 (ja) 2023-09-13 2025-03-20 石原産業株式会社 Ｎ－置換オキシアミド化合物又はその塩
AU2024400853A1 (en) 2023-12-15 2026-05-28 Ishihara Sangyo Kaisha, Ltd. N-substituted oxy-2-aminothiazolecarboxamide compound or salt thereof and agricultural and horticultural fungicide

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
US5595872A (en) 1992-03-06 1997-01-21 Bristol-Myers Squibb Company Nucleic acids encoding microsomal trigyceride transfer protein
US5739135A (en) 1993-09-03 1998-04-14 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5962440A (en) 1996-05-09 1999-10-05 Bristol-Myers Squibb Company Cyclic phosphonate ester inhibitors of microsomal triglyceride transfer protein and method
US5827875A (en) 1996-05-10 1998-10-27 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5885983A (en) 1996-05-10 1999-03-23 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5760246A (en) 1996-12-17 1998-06-02 Biller; Scott A. Conformationally restricted aromatic inhibitors of microsomal triglyceride transfer protein and method
NZ534946A (en) * 2002-03-13 2007-05-31 Merck & Co Inc Fluorinated 4-azasteroid derivatives as androgen receptor modulators
AU2003296414A1 (en) 2002-12-12 2004-07-09 Pharmacia Corporation Method of using aminocyanopyridine compounds as mitogen activated protein kinase-activated protein kinase-2 inhibitors
TW200503994A (en) * 2003-01-24 2005-02-01 Novartis Ag Organic compounds
US7625921B2 (en) 2004-01-16 2009-12-01 Bristol-Myers Squibb Company Modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
US8034940B2 (en) * 2006-08-09 2011-10-11 Bristol-Myers Squibb Company Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof

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Publication number Publication date
WO2009100171A1 (en) 2009-08-13
US20110002952A1 (en) 2011-01-06
US8304539B2 (en) 2012-11-06
CN101990541A (zh) 2011-03-23
EP2247597A1 (en) 2010-11-10

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