JP2011508791A5 - - Google Patents
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- Publication number
- JP2011508791A5 JP2011508791A5 JP2010542440A JP2010542440A JP2011508791A5 JP 2011508791 A5 JP2011508791 A5 JP 2011508791A5 JP 2010542440 A JP2010542440 A JP 2010542440A JP 2010542440 A JP2010542440 A JP 2010542440A JP 2011508791 A5 JP2011508791 A5 JP 2011508791A5
- Authority
- JP
- Japan
- Prior art keywords
- lactide
- drug depot
- implantable drug
- fluocinolone
- biodegradable polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229940079593 drug Drugs 0.000 claims 20
- 239000003814 drug Substances 0.000 claims 20
- FEBLZLNTKCEFIT-VSXGLTOVSA-N fluocinolone acetonide Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O FEBLZLNTKCEFIT-VSXGLTOVSA-N 0.000 claims 10
- 229920002988 biodegradable polymer Polymers 0.000 claims 9
- 239000004621 biodegradable polymer Substances 0.000 claims 9
- 229940043075 fluocinolone Drugs 0.000 claims 8
- 206010061218 Inflammation Diseases 0.000 claims 7
- 208000002193 Pain Diseases 0.000 claims 7
- 230000004054 inflammatory process Effects 0.000 claims 7
- 229920001606 poly(lactic acid-co-glycolic acid) Polymers 0.000 claims 7
- 150000003839 salts Chemical class 0.000 claims 7
- JJTUDXZGHPGLLC-IMJSIDKUSA-N 4511-42-6 Chemical compound C[C@@H]1OC(=O)[C@H](C)OC1=O JJTUDXZGHPGLLC-IMJSIDKUSA-N 0.000 claims 6
- 206010052779 Transplant rejections Diseases 0.000 claims 6
- 229920000747 poly(lactic acid) Polymers 0.000 claims 6
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Polymers OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 claims 2
- 229920000954 Polyglycolide Polymers 0.000 claims 2
- 229960001347 fluocinolone acetonide Drugs 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 229920002643 polyglutamic acid Polymers 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- SCRCZNMJAVGGEI-UHFFFAOYSA-N 1,4-dioxane-2,5-dione;oxepan-2-one Chemical compound O=C1COC(=O)CO1.O=C1CCCCCO1 SCRCZNMJAVGGEI-UHFFFAOYSA-N 0.000 claims 1
- 229920001710 Polyorthoester Polymers 0.000 claims 1
- 208000008765 Sciatica Diseases 0.000 claims 1
- 239000007943 implant Substances 0.000 claims 1
- JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical compound CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 claims 1
- 239000002745 poly(ortho ester) Substances 0.000 claims 1
- PAPBSGBWRJIAAV-UHFFFAOYSA-N ε-Caprolactone Chemical compound O=C1CCCCCO1 PAPBSGBWRJIAAV-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4621808P | 2008-04-18 | 2008-04-18 | |
| US12/413,197 US9125917B2 (en) | 2008-04-18 | 2009-03-27 | Fluocinolone formulations in a biodegradable polymer carrier |
| PCT/US2009/041043 WO2009129511A2 (en) | 2008-04-18 | 2009-04-17 | Fluocinolone formulations in a biodegradable polymer carrier |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011508791A JP2011508791A (ja) | 2011-03-17 |
| JP2011508791A5 true JP2011508791A5 (https=) | 2011-05-12 |
Family
ID=41199779
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010542440A Pending JP2011508791A (ja) | 2008-04-18 | 2009-04-17 | 生物分解性ポリマー担体中のフルオシノロン製剤 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US9125917B2 (https=) |
| EP (1) | EP2280712A4 (https=) |
| JP (1) | JP2011508791A (https=) |
| CN (1) | CN101959520A (https=) |
| WO (1) | WO2009129511A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US20090110637A1 (en) * | 2007-10-26 | 2009-04-30 | Warsaw Orthopedic, Inc. | LMP and Regulation of Tissue Growth |
| USRE48948E1 (en) | 2008-04-18 | 2022-03-01 | Warsaw Orthopedic, Inc. | Clonidine compounds in a biodegradable polymer |
| US20100239632A1 (en) | 2009-03-23 | 2010-09-23 | Warsaw Orthopedic, Inc. | Drug depots for treatment of pain and inflammation in sinus and nasal cavities or cardiac tissue |
| US20110027331A1 (en) * | 2009-07-29 | 2011-02-03 | Warsaw Orthopedic, Inc. | An implantable drug depot having a reversible phase transition material for treatment of pain and/or inflammation |
| GB201505527D0 (en) | 2015-03-31 | 2015-05-13 | Jmedtech Pte Ltd | Composition |
| WO2019071245A1 (en) | 2017-10-06 | 2019-04-11 | Foundry Therapeutics, Inc. | IMPLANTABLE DEPOSITS FOR REGULATED RELEASE OF ANALGESICS TO TREAT POSTHOPERATIVE PAIN ASSOCIATED WITH ORTHOPEDIC SURGERY, AND RELATED DEVICES, SYSTEMS, AND METHODS |
| CN116650732A (zh) | 2018-01-08 | 2023-08-29 | 铸造疗法股份有限公司 | 经由治疗剂的控制递送用于治疗腔内癌症的装置、系统和方法 |
| WO2019159062A1 (en) | 2018-02-13 | 2019-08-22 | Murphy Kieran P | Delivery system for delivering a drug depot to a target site under image guidance and methods and uses of same |
| US12458589B2 (en) | 2018-05-12 | 2025-11-04 | Foundry Therapeutics, Inc. | Implantable polymer depots for the controlled release of therapeutic agents |
| WO2020047013A1 (en) | 2018-08-28 | 2020-03-05 | Foundry Therapeutics, Inc. | Polymer implants |
| US12383246B2 (en) | 2020-10-12 | 2025-08-12 | Abbott Cardiovascular Systems, Inc. | Vessel closure device with improved safety and tract hemostasis |
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| US6179862B1 (en) * | 1998-08-14 | 2001-01-30 | Incept Llc | Methods and apparatus for in situ formation of hydrogels |
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| KR101341359B1 (ko) * | 2004-10-01 | 2013-12-13 | 램스코르 인코포레이티드 | 편리하게 이식가능한 서방형 약물 조성물 |
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| US7741273B2 (en) * | 2006-04-13 | 2010-06-22 | Warsaw Orthopedic, Inc. | Drug depot implant designs |
| US8802128B2 (en) * | 2006-06-23 | 2014-08-12 | Allergan, Inc. | Steroid-containing sustained release intraocular implants and related methods |
| US20080091207A1 (en) * | 2006-10-13 | 2008-04-17 | Csaba Truckai | Bone treatment systems and methods |
-
2009
- 2009-03-27 US US12/413,197 patent/US9125917B2/en active Active
- 2009-04-17 EP EP09733217A patent/EP2280712A4/en not_active Withdrawn
- 2009-04-17 JP JP2010542440A patent/JP2011508791A/ja active Pending
- 2009-04-17 CN CN2009801006021A patent/CN101959520A/zh active Pending
- 2009-04-17 WO PCT/US2009/041043 patent/WO2009129511A2/en not_active Ceased
-
2015
- 2015-09-04 US US14/846,067 patent/US9763966B2/en active Active
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