JP2011508791A5 - - Google Patents
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- Publication number
- JP2011508791A5 JP2011508791A5 JP2010542440A JP2010542440A JP2011508791A5 JP 2011508791 A5 JP2011508791 A5 JP 2011508791A5 JP 2010542440 A JP2010542440 A JP 2010542440A JP 2010542440 A JP2010542440 A JP 2010542440A JP 2011508791 A5 JP2011508791 A5 JP 2011508791A5
- Authority
- JP
- Japan
- Prior art keywords
- lactide
- drug depot
- implantable drug
- fluocinolone
- biodegradable polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229940079593 drug Drugs 0.000 claims 20
- 239000003814 drug Substances 0.000 claims 20
- FEBLZLNTKCEFIT-VSXGLTOVSA-N fluocinolone acetonide Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O FEBLZLNTKCEFIT-VSXGLTOVSA-N 0.000 claims 10
- 229920002988 biodegradable polymer Polymers 0.000 claims 9
- 239000004621 biodegradable polymer Substances 0.000 claims 9
- 229940043075 fluocinolone Drugs 0.000 claims 8
- 206010061218 Inflammation Diseases 0.000 claims 7
- 208000002193 Pain Diseases 0.000 claims 7
- 230000004054 inflammatory process Effects 0.000 claims 7
- 229920001606 poly(lactic acid-co-glycolic acid) Polymers 0.000 claims 7
- 150000003839 salts Chemical class 0.000 claims 7
- JJTUDXZGHPGLLC-IMJSIDKUSA-N 4511-42-6 Chemical compound C[C@@H]1OC(=O)[C@H](C)OC1=O JJTUDXZGHPGLLC-IMJSIDKUSA-N 0.000 claims 6
- 206010052779 Transplant rejections Diseases 0.000 claims 6
- 229920000747 poly(lactic acid) Polymers 0.000 claims 6
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Polymers OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 claims 2
- 229920000954 Polyglycolide Polymers 0.000 claims 2
- 229960001347 fluocinolone acetonide Drugs 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 229920002643 polyglutamic acid Polymers 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- SCRCZNMJAVGGEI-UHFFFAOYSA-N 1,4-dioxane-2,5-dione;oxepan-2-one Chemical compound O=C1COC(=O)CO1.O=C1CCCCCO1 SCRCZNMJAVGGEI-UHFFFAOYSA-N 0.000 claims 1
- 229920001710 Polyorthoester Polymers 0.000 claims 1
- 208000008765 Sciatica Diseases 0.000 claims 1
- 239000007943 implant Substances 0.000 claims 1
- JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical compound CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 claims 1
- 239000002745 poly(ortho ester) Substances 0.000 claims 1
- PAPBSGBWRJIAAV-UHFFFAOYSA-N ε-Caprolactone Chemical compound O=C1CCCCCO1 PAPBSGBWRJIAAV-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4621808P | 2008-04-18 | 2008-04-18 | |
| US12/413,197 US9125917B2 (en) | 2008-04-18 | 2009-03-27 | Fluocinolone formulations in a biodegradable polymer carrier |
| PCT/US2009/041043 WO2009129511A2 (en) | 2008-04-18 | 2009-04-17 | Fluocinolone formulations in a biodegradable polymer carrier |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011508791A JP2011508791A (ja) | 2011-03-17 |
| JP2011508791A5 true JP2011508791A5 (https=) | 2011-05-12 |
Family
ID=41199779
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010542440A Pending JP2011508791A (ja) | 2008-04-18 | 2009-04-17 | 生物分解性ポリマー担体中のフルオシノロン製剤 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US9125917B2 (https=) |
| EP (1) | EP2280712A4 (https=) |
| JP (1) | JP2011508791A (https=) |
| CN (1) | CN101959520A (https=) |
| WO (1) | WO2009129511A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090110637A1 (en) * | 2007-10-26 | 2009-04-30 | Warsaw Orthopedic, Inc. | LMP and Regulation of Tissue Growth |
| USRE48948E1 (en) | 2008-04-18 | 2022-03-01 | Warsaw Orthopedic, Inc. | Clonidine compounds in a biodegradable polymer |
| US20100239632A1 (en) | 2009-03-23 | 2010-09-23 | Warsaw Orthopedic, Inc. | Drug depots for treatment of pain and inflammation in sinus and nasal cavities or cardiac tissue |
| US20110027331A1 (en) * | 2009-07-29 | 2011-02-03 | Warsaw Orthopedic, Inc. | An implantable drug depot having a reversible phase transition material for treatment of pain and/or inflammation |
| GB201505527D0 (en) | 2015-03-31 | 2015-05-13 | Jmedtech Pte Ltd | Composition |
| WO2019071245A1 (en) | 2017-10-06 | 2019-04-11 | Foundry Therapeutics, Inc. | IMPLANTABLE DEPOSITS FOR REGULATED RELEASE OF ANALGESICS TO TREAT POSTHOPERATIVE PAIN ASSOCIATED WITH ORTHOPEDIC SURGERY, AND RELATED DEVICES, SYSTEMS, AND METHODS |
| WO2019136490A1 (en) | 2018-01-08 | 2019-07-11 | Foundry Therapeutics, Inc. | Devices, systems, and methods for treating intraluminal cancer via controlled delivery of therapeutic agents |
| EP3752239A4 (en) | 2018-02-13 | 2021-11-03 | Kieran P. Murphy | DELIVERY SYSTEM FOR IMAGE-CONTROLLED DELIVERY OF A DRUG DEPOT TO A DESTINATION, AND PROCEDURES AND USES THEREOF |
| EP3793536A1 (en) | 2018-05-12 | 2021-03-24 | Foundry Therapeutics, Inc. | Implantable polymer depots for the controlled release of therapeutic agents |
| US12303619B2 (en) | 2018-08-28 | 2025-05-20 | Foundry Therapeutics, Inc. | Polymer implants |
| US12383246B2 (en) | 2020-10-12 | 2025-08-12 | Abbott Cardiovascular Systems, Inc. | Vessel closure device with improved safety and tract hemostasis |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4624255A (en) | 1982-02-18 | 1986-11-25 | Schenck Robert R | Apparatus for anastomosing living vessels |
| US4863457A (en) | 1986-11-24 | 1989-09-05 | Lee David A | Drug delivery device |
| US5922340A (en) | 1992-09-10 | 1999-07-13 | Children's Medical Center Corporation | High load formulations and methods for providing prolonged local anesthesia |
| US5868789A (en) | 1997-02-03 | 1999-02-09 | Huebner; Randall J. | Removable suture anchor apparatus |
| US5522844A (en) | 1993-06-22 | 1996-06-04 | Johnson; Lanny L. | Suture anchor, suture anchor installation device and method for attaching a suture to a bone |
| WO1996024330A1 (en) * | 1995-02-10 | 1996-08-15 | Medtronic, Inc. | Method and device for administering analgesics |
| US6046187A (en) | 1996-09-16 | 2000-04-04 | Children's Medical Center Corporation | Formulations and methods for providing prolonged local anesthesia |
| ATE203157T1 (de) | 1996-12-20 | 2001-08-15 | Alza Corp | Injizierbare depotgelzubereitung und herstellungsverfahren |
| US6294170B1 (en) | 1997-08-08 | 2001-09-25 | Amgen Inc. | Composition and method for treating inflammatory diseases |
| US6248345B1 (en) | 1997-07-02 | 2001-06-19 | Euro-Celtique, S.A. | Prolonged anesthesia in joints and body spaces |
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| AU733868B2 (en) | 1998-05-12 | 2001-05-31 | Boston Scientific Limited | Manual bone anchor placement devices |
| US6179862B1 (en) | 1998-08-14 | 2001-01-30 | Incept Llc | Methods and apparatus for in situ formation of hydrogels |
| US6632457B1 (en) | 1998-08-14 | 2003-10-14 | Incept Llc | Composite hydrogel drug delivery systems |
| US6927044B2 (en) | 1998-09-25 | 2005-08-09 | Regeneron Pharmaceuticals, Inc. | IL-1 receptor based cytokine traps |
| US6143314A (en) | 1998-10-28 | 2000-11-07 | Atrix Laboratories, Inc. | Controlled release liquid delivery compositions with low initial drug burst |
| US6565874B1 (en) | 1998-10-28 | 2003-05-20 | Atrix Laboratories | Polymeric delivery formulations of leuprolide with improved efficacy |
| US6436099B1 (en) | 1999-04-23 | 2002-08-20 | Sdgi Holdings, Inc. | Adjustable spinal tether |
| US6287588B1 (en) | 1999-04-29 | 2001-09-11 | Macromed, Inc. | Agent delivering system comprised of microparticle and biodegradable gel with an improved releasing profile and methods of use thereof |
| US7220281B2 (en) | 1999-08-18 | 2007-05-22 | Intrinsic Therapeutics, Inc. | Implant for reinforcing and annulus fibrosis |
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| US7229441B2 (en) | 2001-02-28 | 2007-06-12 | Warsaw Orthopedic, Inc. | Flexible systems for spinal stabilization and fixation |
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| MXPA01011542A (es) | 2001-11-13 | 2003-05-22 | Alcon Inc | Regeneracion del cartilago articular da°ado por la osteoartritis de grado i y ii, mediante la aplicacion intra-articular de una mezcla de hialuronato de sodio y de condroitin sulfato en un vehiculo de gel. |
| US6974462B2 (en) | 2001-12-19 | 2005-12-13 | Boston Scientific Scimed, Inc. | Surgical anchor implantation device |
| AU2003249317B2 (en) | 2002-07-19 | 2007-08-02 | Institute Of Materials Research And Engineering | Biodegradable triblock copolymers, synthesis methods therefor, and hydrogels and biomaterials made there from |
| US20040137059A1 (en) * | 2003-01-09 | 2004-07-15 | Thierry Nivaggioli | Biodegradable ocular implant |
| US20040166088A1 (en) | 2003-01-15 | 2004-08-26 | Shalaby Shalaby W. | Polymeric precursors of non-absorbable, in situ-forming hydrogels and applications thereof |
| US7144412B2 (en) | 2003-06-25 | 2006-12-05 | Wolf Medical Enterprises, Inc. | Gold suture and method of use in wound closure |
| JP5229768B2 (ja) * | 2003-06-26 | 2013-07-03 | シヴィダ・ユーエス・インコーポレイテッド | Ｉｎ−Ｓｉｔｕゲル化薬物輸送システム |
| WO2005000278A1 (en) * | 2003-06-26 | 2005-01-06 | Mediolanum Pharmaceuticals Ltd. | Subcutaneous implants having limited initial release of the active principle and subsequent linearly varying extended release thereof |
| US20050148512A1 (en) | 2003-11-10 | 2005-07-07 | Angiotech International Ag | Medical implants and fibrosis-inducing agents |
| CA2536096A1 (en) | 2004-01-30 | 2005-08-18 | Angiotech International Ag | Compositions and methods for treating contracture |
| US20050226814A1 (en) * | 2004-04-13 | 2005-10-13 | Bausch & Lomb Incorporated | Diagnostic method and kit for implantation of a sustained release drug-delivery implant with a steroid |
| US7410480B2 (en) | 2004-04-21 | 2008-08-12 | Acclarent, Inc. | Devices and methods for delivering therapeutic substances for the treatment of sinusitis and other disorders |
| US7361168B2 (en) | 2004-04-21 | 2008-04-22 | Acclarent, Inc. | Implantable device and methods for delivering drugs and other substances to treat sinusitis and other disorders |
| US8119154B2 (en) * | 2004-04-30 | 2012-02-21 | Allergan, Inc. | Sustained release intraocular implants and related methods |
| WO2005121394A1 (ja) * | 2004-06-07 | 2005-12-22 | Ulvac, Inc. | マグネトロンスパッタリング方法及びマグネトロンスパッタリング装置 |
| EP2452670A1 (en) * | 2004-10-01 | 2012-05-16 | Ramscor, Inc. | Conveniently implantable sustained release drug compositions |
| EA200701131A1 (ru) | 2004-11-24 | 2007-12-28 | Алгоркс Фармасьютикалз, Инк. | Гелеобразная препаративная форма капсаициноида и способы её применения |
| US7611494B2 (en) | 2005-02-08 | 2009-11-03 | Confluent Surgical, Inc. | Spray for fluent materials |
| US7610100B2 (en) | 2005-12-30 | 2009-10-27 | Boston Scientific Neuromodulation Corporation | Methods and systems for treating osteoarthritis |
| US7741273B2 (en) | 2006-04-13 | 2010-06-22 | Warsaw Orthopedic, Inc. | Drug depot implant designs |
| US8802128B2 (en) * | 2006-06-23 | 2014-08-12 | Allergan, Inc. | Steroid-containing sustained release intraocular implants and related methods |
| US20080091207A1 (en) | 2006-10-13 | 2008-04-17 | Csaba Truckai | Bone treatment systems and methods |
-
2009
- 2009-03-27 US US12/413,197 patent/US9125917B2/en active Active
- 2009-04-17 WO PCT/US2009/041043 patent/WO2009129511A2/en not_active Ceased
- 2009-04-17 JP JP2010542440A patent/JP2011508791A/ja active Pending
- 2009-04-17 EP EP09733217A patent/EP2280712A4/en not_active Withdrawn
- 2009-04-17 CN CN2009801006021A patent/CN101959520A/zh active Pending
-
2015
- 2015-09-04 US US14/846,067 patent/US9763966B2/en active Active
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