JP2011505829A5 - - Google Patents
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- Publication number
- JP2011505829A5 JP2011505829A5 JP2010537899A JP2010537899A JP2011505829A5 JP 2011505829 A5 JP2011505829 A5 JP 2011505829A5 JP 2010537899 A JP2010537899 A JP 2010537899A JP 2010537899 A JP2010537899 A JP 2010537899A JP 2011505829 A5 JP2011505829 A5 JP 2011505829A5
- Authority
- JP
- Japan
- Prior art keywords
- primer pair
- gene
- genes
- marker gene
- steroid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 108090000623 proteins and genes Proteins 0.000 claims 20
- 239000003550 marker Substances 0.000 claims 14
- 238000000034 method Methods 0.000 claims 13
- 150000003431 steroids Chemical class 0.000 claims 8
- 108010009992 CD163 antigen Proteins 0.000 claims 6
- 108091034117 Oligonucleotide Proteins 0.000 claims 6
- 210000004027 cell Anatomy 0.000 claims 6
- 230000002519 immonomodulatory effect Effects 0.000 claims 6
- 238000002560 therapeutic procedure Methods 0.000 claims 4
- 230000003321 amplification Effects 0.000 claims 3
- 230000001747 exhibiting effect Effects 0.000 claims 3
- 238000003199 nucleic acid amplification method Methods 0.000 claims 3
- 101150060219 tsp-1 gene Proteins 0.000 claims 3
- 102100034428 Dual specificity protein phosphatase 1 Human genes 0.000 claims 2
- 101710132784 Dual specificity protein phosphatase 1 Proteins 0.000 claims 2
- 101000831567 Homo sapiens Toll-like receptor 2 Proteins 0.000 claims 2
- 101000669447 Homo sapiens Toll-like receptor 4 Proteins 0.000 claims 2
- 101000606067 Homo sapiens Tyrosine-protein kinase TXK Proteins 0.000 claims 2
- -1 IL1-R2 Proteins 0.000 claims 2
- 102100024333 Toll-like receptor 2 Human genes 0.000 claims 2
- 102100039360 Toll-like receptor 4 Human genes 0.000 claims 2
- 102100039079 Tyrosine-protein kinase TXK Human genes 0.000 claims 2
- 238000002648 combination therapy Methods 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 208000024891 symptom Diseases 0.000 claims 2
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 1
- 206010009900 Colitis ulcerative Diseases 0.000 claims 1
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 206010014561 Emphysema Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 1
- 208000024716 acute asthma Diseases 0.000 claims 1
- 230000001154 acute effect Effects 0.000 claims 1
- 238000004458 analytical method Methods 0.000 claims 1
- 210000000601 blood cell Anatomy 0.000 claims 1
- 208000023819 chronic asthma Diseases 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 230000001419 dependent effect Effects 0.000 claims 1
- 208000027866 inflammatory disease Diseases 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 238000007689 inspection Methods 0.000 claims 1
- 210000003819 peripheral blood mononuclear cell Anatomy 0.000 claims 1
- 238000011002 quantification Methods 0.000 claims 1
- 238000003753 real-time PCR Methods 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 230000001235 sensitizing effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0702789 | 2007-12-14 | ||
| SE0702789-9 | 2007-12-14 | ||
| PCT/SE2008/051446 WO2009078793A1 (en) | 2007-12-14 | 2008-12-12 | Method for predicting the response to a therapy |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011505829A JP2011505829A (ja) | 2011-03-03 |
| JP2011505829A5 true JP2011505829A5 (enExample) | 2012-02-02 |
| JP5514733B2 JP5514733B2 (ja) | 2014-06-04 |
Family
ID=40795763
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010537899A Active JP5514733B2 (ja) | 2007-12-14 | 2008-12-12 | 療法に対する応答を予測するための方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8574834B2 (enExample) |
| EP (1) | EP2220489B1 (enExample) |
| JP (1) | JP5514733B2 (enExample) |
| AU (1) | AU2008339090A1 (enExample) |
| CA (1) | CA2708267C (enExample) |
| WO (1) | WO2009078793A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140030735A1 (en) * | 2011-03-07 | 2014-01-30 | Temple University - Of The Commonwealth System Of Higher Education | Biomarkers of chronic obstructive pulmonary disease |
| US11560594B2 (en) * | 2015-02-05 | 2023-01-24 | Duke University | Methods of detecting osteoarthritis and predicting progression thereof |
| AU2017368050A1 (en) | 2016-11-29 | 2019-06-20 | Puretech Lyt, Inc. | Exosomes for delivery of therapeutic agents |
| US20200360364A1 (en) * | 2018-01-31 | 2020-11-19 | Flagship Pioneering Innovations V, Inc. | Methods and compositions for treating inflammatory or autoimmune diseases or conditions using chrna6 activators |
| WO2022246048A2 (en) * | 2021-05-20 | 2022-11-24 | Trustees Of Boston University | Methods and compositions relating to airway dysfunction |
| JP7710407B2 (ja) * | 2022-03-31 | 2025-07-18 | 日立建機株式会社 | 作業機械 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002300883A (ja) * | 2001-04-05 | 2002-10-15 | Jenokkusu Soyaku Kenkyusho:Kk | ステロイド応答性の検査方法 |
| US7384736B2 (en) | 2001-09-06 | 2008-06-10 | Decode Genetics Ehf. | Methods for predicting drug sensitivity in patients afflicted with an inflammatory disease |
| AU2003212822A1 (en) | 2002-01-22 | 2003-09-02 | Trustees Of The University Of Pennsylvania | Methods for determining drug responsiveness |
| WO2005116268A2 (en) * | 2004-05-27 | 2005-12-08 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health | Differential expression of molecules associated with acute stroke |
| DE602006015963D1 (de) * | 2005-07-01 | 2010-09-16 | Index Pharmaceuticals Ab | Immunstimulatorisches verfahren |
| AU2006306805A1 (en) | 2005-10-28 | 2007-05-03 | Index Pharmaceuticals Ab | Composition and method for the prevention, treatment and/or alleviation of an inflammatory disease |
| WO2008051290A2 (en) | 2006-04-07 | 2008-05-02 | Xdx, Inc. | Steroid responsive nucleic acid expression and prediction of disease activity |
-
2008
- 2008-12-12 JP JP2010537899A patent/JP5514733B2/ja active Active
- 2008-12-12 AU AU2008339090A patent/AU2008339090A1/en not_active Abandoned
- 2008-12-12 US US12/746,758 patent/US8574834B2/en not_active Expired - Fee Related
- 2008-12-12 CA CA2708267A patent/CA2708267C/en not_active Expired - Fee Related
- 2008-12-12 EP EP08862903.5A patent/EP2220489B1/en not_active Not-in-force
- 2008-12-12 WO PCT/SE2008/051446 patent/WO2009078793A1/en not_active Ceased
-
2013
- 2013-10-03 US US14/045,357 patent/US20140030723A1/en not_active Abandoned
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