JP2011504736A5 - - Google Patents
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- Publication number
- JP2011504736A5 JP2011504736A5 JP2010535301A JP2010535301A JP2011504736A5 JP 2011504736 A5 JP2011504736 A5 JP 2011504736A5 JP 2010535301 A JP2010535301 A JP 2010535301A JP 2010535301 A JP2010535301 A JP 2010535301A JP 2011504736 A5 JP2011504736 A5 JP 2011504736A5
- Authority
- JP
- Japan
- Prior art keywords
- pulmonary
- pharmaceutical composition
- nucleic acid
- hypertension
- acid molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010064911 Pulmonary arterial hypertension Diseases 0.000 claims 8
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- 150000007523 nucleic acids Chemical class 0.000 claims 7
- 102000039446 nucleic acids Human genes 0.000 claims 7
- 108020004707 nucleic acids Proteins 0.000 claims 7
- 230000004048 modification Effects 0.000 claims 5
- 238000012986 modification Methods 0.000 claims 5
- 208000002815 pulmonary hypertension Diseases 0.000 claims 5
- 230000001684 chronic effect Effects 0.000 claims 2
- 102100021943 C-C motif chemokine 2 Human genes 0.000 claims 1
- 101710155857 C-C motif chemokine 2 Proteins 0.000 claims 1
- 102000029816 Collagenase Human genes 0.000 claims 1
- 108060005980 Collagenase Proteins 0.000 claims 1
- 208000005189 Embolism Diseases 0.000 claims 1
- 208000004248 Familial Primary Pulmonary Hypertension Diseases 0.000 claims 1
- 208000021124 Heritable pulmonary arterial hypertension Diseases 0.000 claims 1
- 206010021143 Hypoxia Diseases 0.000 claims 1
- 208000020875 Idiopathic pulmonary arterial hypertension Diseases 0.000 claims 1
- 208000019693 Lung disease Diseases 0.000 claims 1
- 208000007536 Thrombosis Diseases 0.000 claims 1
- 208000015669 capillary disease Diseases 0.000 claims 1
- 229960002424 collagenase Drugs 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 208000019622 heart disease Diseases 0.000 claims 1
- 230000007954 hypoxia Effects 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 208000037997 venous disease Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07023267 | 2007-11-30 | ||
| EP07023267.3 | 2007-11-30 | ||
| PCT/EP2008/010167 WO2009068318A1 (en) | 2007-11-30 | 2008-11-29 | Mcp-i binding nucleic acids and use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011504736A JP2011504736A (ja) | 2011-02-17 |
| JP2011504736A5 true JP2011504736A5 (https=) | 2015-07-02 |
| JP5777341B2 JP5777341B2 (ja) | 2015-09-09 |
Family
ID=40415282
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010535301A Expired - Fee Related JP5777341B2 (ja) | 2007-11-30 | 2008-11-29 | Ｍｃｐ−１結合核酸およびその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20100311816A1 (https=) |
| EP (1) | EP2229442A1 (https=) |
| JP (1) | JP5777341B2 (https=) |
| KR (1) | KR20100092463A (https=) |
| CN (1) | CN101878305A (https=) |
| AU (1) | AU2008329070B2 (https=) |
| BR (1) | BRPI0819845A2 (https=) |
| CA (1) | CA2707089A1 (https=) |
| MX (1) | MX2010005916A (https=) |
| RU (1) | RU2542973C2 (https=) |
| WO (1) | WO2009068318A1 (https=) |
| ZA (1) | ZA201002974B (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2135949T3 (da) | 2006-02-14 | 2013-02-04 | Noxxon Pharma Ag | MCP-1-bindende nukleinsyrer |
| CN101878305A (zh) * | 2007-11-30 | 2010-11-03 | 诺松制药股份公司 | 结合mcp-1的核酸及其用途 |
| WO2012025251A1 (en) | 2010-08-27 | 2012-03-01 | Noxxon Pharma Ag | Nucleic acids for treatment of chronic complications of diabetes |
| CN102621331B (zh) * | 2012-04-05 | 2014-07-30 | 中国医学科学院病原生物学研究所 | 一种检测或辅助检测结核性胸膜炎的试剂盒 |
| EP3065744B1 (en) * | 2013-11-04 | 2021-04-21 | Noxxon Pharma AG | A ccl2 antagonist for use in treating proteinuria |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6670321B1 (en) * | 1998-12-30 | 2003-12-30 | The Children's Medical Center Corporation | Prevention and treatment for retinal ischemia and edema |
| EP1386004A4 (en) * | 2001-04-05 | 2005-02-16 | Ribozyme Pharm Inc | MODULATION OF GENE EXPRESSION ASSOCIATED WITH INFLAMMATORY PROLIFERATION AND GROWTH OF NEURITIES BY METHODS INVOLVING NUCLEIC ACID |
| ATE469164T1 (de) * | 2001-10-26 | 2010-06-15 | Noxxon Pharma Ag | Modifizierte l-nukleinsäure |
| EP1501929B1 (de) * | 2002-05-06 | 2013-03-27 | Noxxon Pharma AG | Cgrp bindende nukleinsäuren |
| EP1530635B1 (en) * | 2002-08-01 | 2011-06-15 | Noxxon Pharma AG | Ghrelin binding nucleic acids |
| AU2004231087B2 (en) * | 2003-04-15 | 2007-01-04 | Merck Sharp & Dohme Corp. | Benzoxazinyl-amidocyclopentyl-heterocyclic modulators of chemokine receptors |
| WO2005084412A2 (en) * | 2004-03-05 | 2005-09-15 | Archemix Corp. | Controlled modulation of the pharmacokinetics and biodistribution of aptamer therapeutics |
| US20060257359A1 (en) * | 2005-02-28 | 2006-11-16 | Cedric Francois | Modifying macrophage phenotype for treatment of disease |
| DK2135949T3 (da) * | 2006-02-14 | 2013-02-04 | Noxxon Pharma Ag | MCP-1-bindende nukleinsyrer |
| US8367629B2 (en) * | 2006-02-14 | 2013-02-05 | Noxxon Pharma Ag | MCP-1 binding nucleic acids and use thereof |
| CN101878305A (zh) * | 2007-11-30 | 2010-11-03 | 诺松制药股份公司 | 结合mcp-1的核酸及其用途 |
-
2008
- 2008-11-29 CN CN2008801184556A patent/CN101878305A/zh active Pending
- 2008-11-29 EP EP08855575A patent/EP2229442A1/en not_active Withdrawn
- 2008-11-29 CA CA2707089A patent/CA2707089A1/en not_active Abandoned
- 2008-11-29 WO PCT/EP2008/010167 patent/WO2009068318A1/en not_active Ceased
- 2008-11-29 BR BRPI0819845-4A patent/BRPI0819845A2/pt active Search and Examination
- 2008-11-29 RU RU2010126662/10A patent/RU2542973C2/ru not_active IP Right Cessation
- 2008-11-29 AU AU2008329070A patent/AU2008329070B2/en not_active Ceased
- 2008-11-29 MX MX2010005916A patent/MX2010005916A/es active IP Right Grant
- 2008-11-29 JP JP2010535301A patent/JP5777341B2/ja not_active Expired - Fee Related
- 2008-11-29 US US12/745,545 patent/US20100311816A1/en not_active Abandoned
- 2008-11-29 KR KR1020107011757A patent/KR20100092463A/ko not_active Ceased
-
2010
- 2010-04-29 ZA ZA2010/02974A patent/ZA201002974B/en unknown
-
2014
- 2014-05-15 US US14/277,826 patent/US20150141496A1/en not_active Abandoned
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