JP2011500814A5 - - Google Patents
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- Publication number
- JP2011500814A5 JP2011500814A5 JP2010531058A JP2010531058A JP2011500814A5 JP 2011500814 A5 JP2011500814 A5 JP 2011500814A5 JP 2010531058 A JP2010531058 A JP 2010531058A JP 2010531058 A JP2010531058 A JP 2010531058A JP 2011500814 A5 JP2011500814 A5 JP 2011500814A5
- Authority
- JP
- Japan
- Prior art keywords
- mammal
- molecular entity
- cyclic peptide
- antibody
- analog
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000124008 Mammalia Species 0.000 claims 15
- 238000000034 method Methods 0.000 claims 13
- 108010069514 Cyclic Peptides Proteins 0.000 claims 9
- 102000001189 Cyclic Peptides Human genes 0.000 claims 9
- 230000002163 immunogen Effects 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 5
- 229920000642 polymer Polymers 0.000 claims 5
- 239000000126 substance Substances 0.000 claims 5
- 230000018612 quorum sensing Effects 0.000 claims 4
- 241000191967 Staphylococcus aureus Species 0.000 claims 3
- 125000000539 amino acid group Chemical group 0.000 claims 3
- 230000028993 immune response Effects 0.000 claims 3
- 208000015181 infectious disease Diseases 0.000 claims 3
- 125000005647 linker group Chemical group 0.000 claims 3
- 235000001014 amino acid Nutrition 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 238000010255 intramuscular injection Methods 0.000 claims 2
- 239000007927 intramuscular injection Substances 0.000 claims 2
- 238000007912 intraperitoneal administration Methods 0.000 claims 2
- 238000001990 intravenous administration Methods 0.000 claims 2
- 235000018102 proteins Nutrition 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 238000007920 subcutaneous administration Methods 0.000 claims 2
- DJQYYYCQOZMCRC-UHFFFAOYSA-N 2-aminopropane-1,3-dithiol Chemical group SCC(N)CS DJQYYYCQOZMCRC-UHFFFAOYSA-N 0.000 claims 1
- 125000000729 N-terminal amino-acid group Chemical group 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 150000002678 macrocyclic compounds Chemical class 0.000 claims 1
- 239000002105 nanoparticle Substances 0.000 claims 1
- 230000003472 neutralizing effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98259307P | 2007-10-25 | 2007-10-25 | |
| US60/982,593 | 2007-10-25 | ||
| PCT/US2008/012151 WO2009055054A2 (en) | 2007-10-25 | 2008-10-24 | Antibody-mediated disruption of quorum sensing in bacteria |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014124700A Division JP6183910B2 (ja) | 2007-10-25 | 2014-06-17 | 抗体媒介による細菌のクオラムセンシングの破壊 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011500814A JP2011500814A (ja) | 2011-01-06 |
| JP2011500814A5 true JP2011500814A5 (https=) | 2011-06-02 |
| JP5581490B2 JP5581490B2 (ja) | 2014-09-03 |
Family
ID=40580303
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010531058A Expired - Fee Related JP5581490B2 (ja) | 2007-10-25 | 2008-10-24 | 抗体媒介による細菌のクオラムセンシングの破壊 |
| JP2014124700A Expired - Fee Related JP6183910B2 (ja) | 2007-10-25 | 2014-06-17 | 抗体媒介による細菌のクオラムセンシングの破壊 |
| JP2017140405A Pending JP2018021021A (ja) | 2007-10-25 | 2017-07-19 | 抗体媒介による細菌のクオラムセンシングの破壊 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014124700A Expired - Fee Related JP6183910B2 (ja) | 2007-10-25 | 2014-06-17 | 抗体媒介による細菌のクオラムセンシングの破壊 |
| JP2017140405A Pending JP2018021021A (ja) | 2007-10-25 | 2017-07-19 | 抗体媒介による細菌のクオラムセンシングの破壊 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9394371B2 (https=) |
| EP (2) | EP2842565B1 (https=) |
| JP (3) | JP5581490B2 (https=) |
| KR (1) | KR101557173B1 (https=) |
| CN (2) | CN104211775A (https=) |
| AU (1) | AU2008317331B2 (https=) |
| CA (2) | CA2975568A1 (https=) |
| ES (1) | ES2603061T3 (https=) |
| WO (1) | WO2009055054A2 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2928543A1 (en) | 2012-10-26 | 2014-05-01 | Gunnar F. Kaufmann | Anti-infective binding proteins that bind aip2 |
| DE102013211850A1 (de) * | 2013-06-21 | 2014-12-24 | Gilupi Gmbh | Schnelltest zum Nachweisen von Erregermaterial, insbesondere zur Unterstützung der Diagnose einer Sepsis, sowie Kit und Vorrichtung zur Durchführung eines Sepsistests |
| WO2015015003A1 (en) * | 2013-08-01 | 2015-02-05 | Université Catholique de Louvain | Anti-garp protein and uses thereof |
| JP2017509587A (ja) | 2013-12-27 | 2017-04-06 | ノーバス・インターナショナル・インコーポレイテッドＮｏｖｕｓ Ｉｎｔｅｒｎａｔｉｏｎａｌ，Ｉｎｃ． | エトキシル化界面活性剤 |
| EP3981874A1 (en) | 2014-01-29 | 2022-04-13 | KM Biologics Co., Ltd. | Anti-transthyretin human antibody |
| EP3101131B1 (en) | 2014-01-29 | 2020-08-19 | KM Biologics Co., Ltd. | Anti-transthyretin humanized antibody |
| EP3103808B1 (en) | 2014-02-07 | 2018-08-22 | Miyarisan Pharmaceutical Co., Ltd. | Peptide having activity of inhibiting production of toxin by bacterium belonging to genus clostridium |
| US10821167B2 (en) * | 2016-02-02 | 2020-11-03 | Unm Rainforest Innovations | VLP-based vaccines for targeting Staphylococcus aureus secreted virulence factors |
| WO2018031730A2 (en) * | 2016-08-11 | 2018-02-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Peptide inhibitors of phosphoglycerate mutase and methods of use |
| JP7128829B2 (ja) | 2017-02-17 | 2022-08-31 | マップ バイオファーマシューティカル、インコーポレイテッド | エボラ感染症の処置用のモノクローナル抗体およびカクテル |
| US10584306B2 (en) | 2017-08-11 | 2020-03-10 | Board Of Regents Of The University Of Oklahoma | Surfactant microemulsions |
| JP7373176B2 (ja) * | 2017-08-31 | 2023-11-02 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 皮膚の酵素活性を制御する分子的細菌療法 |
| AU2018331517B2 (en) | 2017-09-15 | 2024-10-03 | Lentigen Technology, Inc. | Compositions and methods for treating cancer with anti-CD19 immunotherapy |
| US10774135B2 (en) | 2017-12-22 | 2020-09-15 | Sorrento Therapeutics, Inc. | Variant antibodies that bind AIP2 |
| CN111684019B (zh) | 2018-02-13 | 2022-08-02 | 住友化学株式会社 | 组合物及成形体 |
| CA3150161A1 (en) | 2019-08-13 | 2021-02-18 | Darlene E. MCCORD | Non-activated, amorphous, ph neutral, two-part bedside-ready clay delivery system that treats pathogen infections in humans and animals |
| CN111573853B (zh) * | 2020-05-29 | 2020-11-20 | 南京大学 | 一种削减生物法处理废水毒性的方法 |
| EP4423197A4 (en) | 2021-10-25 | 2025-08-27 | Darlene E Mccord | COATED MEDICINAL CLAY COMPOSITIONS, PHARMACEUTICAL COMPOSITIONS AND DELIVERY OF CATION SOURCES AND METHODS OF USE THEREOF |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT932613E (pt) * | 1996-05-22 | 2005-06-30 | Univ New York | Expressao de bloqueio de factoes de virulencia em s. aureus |
| US6248329B1 (en) * | 1998-06-01 | 2001-06-19 | Ramaswamy Chandrashekar | Parasitic helminth cuticlin nucleic acid molecules and uses thereof |
| AU2001259734A1 (en) | 2000-05-10 | 2001-11-20 | Princeton University | Compounds and methods for regulating bacterial growth and pathogenesis |
| US7786257B2 (en) * | 2000-12-18 | 2010-08-31 | University Of Kansas | Signal-1/signal-2 bifunctional peptide inhibitors |
| US6463632B2 (en) * | 2001-02-07 | 2002-10-15 | Hans Oetiker Ag Maschinen-Und Apparatefabrik | Guide arrangement for tightening tool emplacement in hose clamps provided with plastically deformable ears |
| CN1164612C (zh) * | 2001-09-11 | 2004-09-01 | 四川新泰克控股有限责任公司 | 人工组合的抗菌工程多肽及其制备方法 |
| ATE550036T1 (de) * | 2002-08-13 | 2012-04-15 | Haptogen Ltd | Verfahren zur behandlung einer bakteriellen infektionskrankheit mittels antikörpern gegen laktone oder gegen von laktonen abgeleiteten signalmolekülen |
-
2008
- 2008-10-24 AU AU2008317331A patent/AU2008317331B2/en not_active Ceased
- 2008-10-24 CN CN201410258364.XA patent/CN104211775A/zh active Pending
- 2008-10-24 US US12/734,273 patent/US9394371B2/en not_active Expired - Fee Related
- 2008-10-24 WO PCT/US2008/012151 patent/WO2009055054A2/en not_active Ceased
- 2008-10-24 ES ES14180831.1T patent/ES2603061T3/es active Active
- 2008-10-24 CA CA2975568A patent/CA2975568A1/en not_active Abandoned
- 2008-10-24 JP JP2010531058A patent/JP5581490B2/ja not_active Expired - Fee Related
- 2008-10-24 EP EP14180831.1A patent/EP2842565B1/en active Active
- 2008-10-24 CA CA2703133A patent/CA2703133C/en active Active
- 2008-10-24 CN CN200880113179.4A patent/CN101835484B/zh not_active Expired - Fee Related
- 2008-10-24 EP EP08841487.5A patent/EP2211889B1/en active Active
- 2008-10-24 KR KR1020107011438A patent/KR101557173B1/ko not_active Expired - Fee Related
-
2014
- 2014-06-17 JP JP2014124700A patent/JP6183910B2/ja not_active Expired - Fee Related
-
2016
- 2016-07-14 US US15/210,450 patent/US20170043020A1/en not_active Abandoned
-
2017
- 2017-07-19 JP JP2017140405A patent/JP2018021021A/ja active Pending
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