JP2011500104A - 薬学的に活性な因子の骨への局在化を促進するための方法および組成物 - Google Patents
薬学的に活性な因子の骨への局在化を促進するための方法および組成物 Download PDFInfo
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- 230000005026 transcription initiation Effects 0.000 description 1
- 230000005030 transcription termination Effects 0.000 description 1
- 230000014621 translational initiation Effects 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 239000003656 tris buffered saline Substances 0.000 description 1
- 241000701447 unidentified baculovirus Species 0.000 description 1
- 241001430294 unidentified retrovirus Species 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
- 238000007740 vapor deposition Methods 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 235000019168 vitamin K Nutrition 0.000 description 1
- 239000011712 vitamin K Substances 0.000 description 1
- 150000003721 vitamin K derivatives Chemical class 0.000 description 1
- 235000019143 vitamin K2 Nutrition 0.000 description 1
- 239000011728 vitamin K2 Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 229940046010 vitamin k Drugs 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
- 210000005253 yeast cell Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/66—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid the modifying agent being a pre-targeting system involving a peptide or protein for targeting specific cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2002/2817—Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nanotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Medical Informatics (AREA)
- Plant Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physical Education & Sports Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91434107P | 2007-04-27 | 2007-04-27 | |
| US12/107,098 US7977313B2 (en) | 2007-04-27 | 2008-04-22 | Methods and compositions for promoting localization of pharmaceutically active agents to bone |
| PCT/US2008/061200 WO2008134329A1 (en) | 2007-04-27 | 2008-04-23 | Methods and compositions for promoting localization of pharmaceutically active agents to bone |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013098149A Division JP2013151561A (ja) | 2007-04-27 | 2013-05-08 | 薬学的に活性な因子の骨への局在化を促進するための方法および組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011500104A true JP2011500104A (ja) | 2011-01-06 |
| JP2011500104A5 JP2011500104A5 (https=) | 2011-06-30 |
Family
ID=39887259
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010506438A Withdrawn JP2011500104A (ja) | 2007-04-27 | 2008-04-23 | 薬学的に活性な因子の骨への局在化を促進するための方法および組成物 |
| JP2013098149A Pending JP2013151561A (ja) | 2007-04-27 | 2013-05-08 | 薬学的に活性な因子の骨への局在化を促進するための方法および組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013098149A Pending JP2013151561A (ja) | 2007-04-27 | 2013-05-08 | 薬学的に活性な因子の骨への局在化を促進するための方法および組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7977313B2 (https=) |
| EP (1) | EP2152075A4 (https=) |
| JP (2) | JP2011500104A (https=) |
| CN (1) | CN101668422A (https=) |
| CA (1) | CA2685329A1 (https=) |
| WO (2) | WO2008133886A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015228848A (ja) * | 2014-06-06 | 2015-12-21 | シスメックス株式会社 | 細胞の回収方法及びその方法に用いられる加工骨 |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101827564A (zh) | 2007-09-04 | 2010-09-08 | 阿费内基有限公司 | 用于将生长因子递送至纤维结缔组织的方法和组合物 |
| US8629106B2 (en) * | 2010-03-16 | 2014-01-14 | Janssen Biotech, Inc. | Affinity peptides toward BMP-2 |
| EP3341397B1 (en) | 2015-08-25 | 2024-12-18 | Histide AG | Compounds for inducing tissue formation and uses thereof |
| IL298067A (en) | 2015-08-25 | 2023-01-01 | Histide Ag | Compounds for inducing tissue formation and their uses |
| JP6890836B2 (ja) | 2015-09-17 | 2021-06-18 | ヒスタイド アクツィエンゲゼルシャフト | 腫瘍細胞を非腫瘍細胞に変換するための医薬的連合体及びその使用 |
| US11834517B2 (en) | 2017-09-18 | 2023-12-05 | Brandeis University | Branched peptides for enzymatic assembly and mitochondria drug delivery |
| WO2019055988A1 (en) * | 2017-09-18 | 2019-03-21 | Brandeis University | BRANCHED PEPTIDES FOR ENZYMATIC ASSEMBLY AND DRUG DELIVERY TO MITOCHONDRIA |
| WO2020041312A1 (en) * | 2018-08-20 | 2020-02-27 | Alliance For Sustainable Energy, Llc | Cellulose nanofiber biomaterial |
| WO2020077265A1 (en) | 2018-10-12 | 2020-04-16 | Theradaptive, Inc. | Polypeptides including a beta-tricalcium phosphate-binding sequence and uses thereof |
| US20240158441A1 (en) * | 2020-03-18 | 2024-05-16 | Brandeis University | Branched peptides for enzymatic assembly and mitochondria drug delivery |
| BR112022020809A2 (pt) | 2020-04-15 | 2023-02-23 | Theradaptive Inc | Composições e métodos para entrega terapêutica direcionada ao osso |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006052840A2 (en) * | 2004-11-04 | 2006-05-18 | University Of Virginia Patent Foundation | Bone tropic peptides |
| WO2006098744A2 (en) * | 2004-06-16 | 2006-09-21 | Affinergy, Inc. | Ifbm’s to promote attachment of target analytes |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7208011B2 (en) * | 2001-08-20 | 2007-04-24 | Conor Medsystems, Inc. | Implantable medical device with drug filled holes |
| US6395253B2 (en) * | 1998-04-23 | 2002-05-28 | The Regents Of The University Of Michigan | Microspheres containing condensed polyanionic bioactive agents and methods for their production |
| US7118737B2 (en) * | 2000-09-08 | 2006-10-10 | Amylin Pharmaceuticals, Inc. | Polymer-modified synthetic proteins |
| US7381426B2 (en) * | 2002-01-24 | 2008-06-03 | Southwest Research Institute | Targeted delivery of bioactive factors to the systemic skeleton |
| AU2003213246A1 (en) * | 2002-02-21 | 2003-09-09 | University Of Virginia Patent Foundation | Bone targeting peptides |
| JP2005185101A (ja) * | 2002-05-30 | 2005-07-14 | National Institute Of Agrobiological Sciences | 植物の全長ｃＤＮＡおよびその利用 |
| US7238669B2 (en) * | 2002-09-11 | 2007-07-03 | The Curators Of The University Of Missouri | Phage-display peptides as novel antimicrobial agents against Haemophilus influenzae |
| US20050106667A1 (en) * | 2003-08-01 | 2005-05-19 | Genentech, Inc | Binding polypeptides with restricted diversity sequences |
| US7163920B2 (en) * | 2003-09-30 | 2007-01-16 | Ethicon, Inc. | Peptide with osteogenic activity |
| US20050208095A1 (en) * | 2003-11-20 | 2005-09-22 | Angiotech International Ag | Polymer compositions and methods for their use |
| US8188219B2 (en) * | 2004-01-28 | 2012-05-29 | The Regents Of The University Of California | Bone morphogenic protein binding peptide |
| WO2006048877A2 (en) * | 2004-11-04 | 2006-05-11 | Fibron Limited | Treatment of b-cell malignancies with fgfr3 inhibitors |
| US7592429B2 (en) * | 2005-05-03 | 2009-09-22 | Ucb Sa | Sclerostin-binding antibody |
| US7807624B2 (en) * | 2006-01-11 | 2010-10-05 | Affinergy, Inc. | Methods and compositions for promoting attachment of cells of endothelial cell lineage to medical devices |
-
2008
- 2008-04-22 US US12/107,098 patent/US7977313B2/en active Active
- 2008-04-23 EP EP08746591A patent/EP2152075A4/en not_active Withdrawn
- 2008-04-23 CN CN200880013441A patent/CN101668422A/zh active Pending
- 2008-04-23 JP JP2010506438A patent/JP2011500104A/ja not_active Withdrawn
- 2008-04-23 WO PCT/US2008/005200 patent/WO2008133886A1/en not_active Ceased
- 2008-04-23 WO PCT/US2008/061200 patent/WO2008134329A1/en not_active Ceased
- 2008-04-23 CA CA002685329A patent/CA2685329A1/en not_active Abandoned
-
2013
- 2013-05-08 JP JP2013098149A patent/JP2013151561A/ja active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006098744A2 (en) * | 2004-06-16 | 2006-09-21 | Affinergy, Inc. | Ifbm’s to promote attachment of target analytes |
| WO2006052840A2 (en) * | 2004-11-04 | 2006-05-18 | University Of Virginia Patent Foundation | Bone tropic peptides |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015228848A (ja) * | 2014-06-06 | 2015-12-21 | シスメックス株式会社 | 細胞の回収方法及びその方法に用いられる加工骨 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20080268015A1 (en) | 2008-10-30 |
| WO2008134329A1 (en) | 2008-11-06 |
| CA2685329A1 (en) | 2008-11-06 |
| US7977313B2 (en) | 2011-07-12 |
| EP2152075A4 (en) | 2011-01-26 |
| EP2152075A1 (en) | 2010-02-17 |
| JP2013151561A (ja) | 2013-08-08 |
| WO2008133886A1 (en) | 2008-11-06 |
| CN101668422A (zh) | 2010-03-10 |
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