JP2011217965A - Contamination prevention method in piping for dialysis - Google Patents

Contamination prevention method in piping for dialysis Download PDF

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JP2011217965A
JP2011217965A JP2010090728A JP2010090728A JP2011217965A JP 2011217965 A JP2011217965 A JP 2011217965A JP 2010090728 A JP2010090728 A JP 2010090728A JP 2010090728 A JP2010090728 A JP 2010090728A JP 2011217965 A JP2011217965 A JP 2011217965A
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dialysis
piping
membrane
connection end
pipe
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JP5736661B2 (en
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Toyohiko Yoshida
豊彦 吉田
Junji Uchino
順司 内野
Yoichi Kamoshita
洋一 鴨下
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Nipro Corp
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Abstract

PROBLEM TO BE SOLVED: To provide a method for preventing contamination in piping for dialysis.SOLUTION: The piping 2 for dialysis is connected to a dialysis water supplier 1 by a connection end 21 and also connected to dialyzers 3 by connection ends 23. In order to prevent the contamination in the piping 2 for dialysis, the piping 2 for dialysis includes: a UF film 4 close to the connection end 21 with the dialysis water supplier 1; and UF films 5 close to the connection ends 23 with the dialyzers 3.

Description

本発明は透析装置の移動などにより発生する透析用配管内の汚染を防止する方法に関する。   The present invention relates to a method for preventing contamination in a dialysis pipe caused by movement of a dialysis machine.

近年、透析治療において、従来取り除いていた尿毒素成分よりも更に分子量の大きい成分を取り除く必要があることが分かり、例えばＨＰＭ（ハイパフォーマンスメンブレン）というポアサイズの大きい透析膜を用いたダイアライザが使用されるようになった。そのため、従来は透析膜で阻止されていた透析液中の不純物が血液側に混入する危険性が高くなっており、透析用水や透析液を清潔に保ち供給することの重要性が増大している。   In recent years, it has been found that in dialysis treatment, it is necessary to remove a component having a higher molecular weight than the uremic toxin component that has been removed in the past. For example, a dialyzer using a dialysis membrane having a large pore size called HPM (high performance membrane) is used Became. For this reason, there is a high risk that impurities in the dialysate that have been blocked by the dialysis membrane will be mixed into the blood side, and the importance of keeping dialysis water and dialysate clean and supplied is increasing. .

透析用水および透析液は、セントラルシステムにより精製および調製され、各末端透析装置までの供給は透析用配管を通して行われる。従って、透析用配管が汚染されてしまうと、汚染部位より下流にある透析装置は全て汚染されてしまうことになる。従来、供給装置またはＲＯ装置（以下、単に供給装置という）から透析装置に供給される透析用水は、ＵＦ膜（エンドトキシン捕捉フィルター）を透過させてエンドトキシンや細菌を除去するよう試みられているが（特許文献１）、透析装置の移動やメンテナンス時など、透析用配管内が解放される機会も多く、そのため透析装置との接続端側が汚染されて透析用配管内全体に汚染が広がる虞があり、問題であった。   Dialysis water and dialysate are purified and prepared by a central system, and supply to each terminal dialysis machine is performed through dialysis piping. Therefore, when the dialysis piping is contaminated, all the dialysis apparatuses downstream from the contaminated site are contaminated. Conventionally, dialysis water supplied to a dialysis apparatus from a supply apparatus or RO apparatus (hereinafter simply referred to as a supply apparatus) has been attempted to remove endotoxin and bacteria by permeating a UF membrane (endotoxin capture filter) ( Patent Document 1), there are many occasions where the inside of the dialysis pipe is released, such as during the movement or maintenance of the dialysis machine, and therefore there is a risk that the connection end side with the dialysis machine will be contaminated and the contamination will spread throughout the dialysis pipe. It was a problem.

また、透析装置内におけるエンドトキシンや細菌を除去するために、従来、透析液供給装置とダイアライザの間に、ダイアライザに近接してＵＦ膜を介在させる方法も採用されているが（特許文献２）、ＵＦ膜の劣化によりこれを３ヶ月に１回程度交換しなければならず、面倒であった。   In addition, in order to remove endotoxin and bacteria in the dialysis machine, conventionally, a method in which a UF membrane is interposed between the dialysate supply apparatus and the dialyzer in the vicinity of the dialyzer has been adopted (Patent Document 2). Due to the deterioration of the UF membrane, it had to be replaced about once every three months, which was troublesome.

特開２００３−２６０１３１号公報、第２欄４５〜４７頁JP 2003-260131 A, second column, pages 45-47. 特開平３−２５４７５５号公報JP-A-3-254755

本発明は、上記の事情に鑑みてなされたもので、透析配用管内の汚染を防止する方法を提供する。   This invention is made | formed in view of said situation, and provides the method of preventing the contamination in a dialysis distribution pipe.

本発明の透析用配管内の汚染防止方法は、透析用配管の透析用水供給装置との接続端側に細菌やエンドトキシンを除去するためのフィルタを設けると共に、透析用配管の透析装置との接続端側に細菌やエンドトキシンを除去するためのフィルタを設けることを特徴とする。
ここで、フィルタは、透析用水供給装置との接続端および透析装置との接続端に近接して設けるのが好ましい。
また、細菌やエンドトキシンを除去するためのフィルタとは、例えば、ＵＦ膜等からなるエンドトキシン捕捉フィルタ（ＥＴＲＦ）や除菌フィルタを言い、透析用水供給装置とは、透析液調製装置に透析用水を供給するための装置を言う。透析用水供給装置にはＲＯ装置も含まれる。 The method for preventing contamination in a dialysis pipe according to the present invention is provided with a filter for removing bacteria and endotoxin on the connection end side of a dialysis pipe with a dialysis water supply device, It is characterized by providing a filter for removing bacteria and endotoxin on the side.
Here, the filter is preferably provided close to the connection end with the dialysis water supply device and the connection end with the dialysis device.
The filter for removing bacteria and endotoxin is, for example, an endotoxin trapping filter (ETRF) or a sterilizing filter made of a UF membrane or the like. Say a device to do. The dialysis water supply device includes an RO device.

以上、一般的に本発明を記述したが、より一層の理解は、いくつかの特定の実施例を参照することによって得ることが出来る。これらの実施例は本明細書に例示の目的のためにのみ提供されるものであり、他の旨が特定されない限り、限定的なものではない。   Although the present invention has been generally described above, a better understanding can be obtained by reference to certain specific embodiments. These examples are provided herein for illustrative purposes only and are not limiting unless otherwise specified.

本発明によれば、以下のような効果が期待できる。すなわち、１）透析用配管の透析用水供給装置との接続端側に細菌やエンドトキシンを除去するためのフィルタを設けると共に、透析用配管の透析装置との接続端側に細菌やエンドトキシンを除去するためのフィルタを設けているので、透析用水の汚染をほぼ完全に防止することが出来る。２）透析液供給装置とダイアライザの間に、ダイアライザに近接して設けたＵＦ膜の劣化が抑制され、膜の寿命が向上し５倍以上の期間性能が維持されるようになったので、ＵＦ膜を交換する手間が大幅に軽減された。   According to the present invention, the following effects can be expected. That is, 1) To provide a filter for removing bacteria and endotoxin on the end of the dialysis pipe connected to the dialysis water supply device, and to remove bacteria and endotoxin on the end of the dialysis pipe connected to the dialyzer Therefore, contamination of dialysis water can be almost completely prevented. 2) Since the deterioration of the UF membrane provided close to the dialyzer between the dialysate supply device and the dialyzer is suppressed, the life of the membrane is improved and the performance is maintained for more than 5 times. The effort to change the membrane has been greatly reduced.

本発明の透析用配管内の汚染防止方法の説明図である。It is explanatory drawing of the contamination prevention method in the piping for dialysis of this invention.

透析用配管の透析用水供給装置との接続端側に接続端に近接してＵＦ膜を設けると共に、透析用配管の透析装置との接続端側に接続端に近接してＵＦ膜を設ける。   A UF membrane is provided near the connection end on the connection end side of the dialysis piping with the dialysis water supply device, and a UF membrane is provided near the connection end on the connection end side of the dialysis piping with the dialysis device.

透析用配管内の汚染防止方法について、図１を用いて説明する。
図１は本発明の透析用配管内の汚染防止方法の説明図であり、シングルパス方式の透析用水配管を示す。
透析用配管２は、透析用水供給装置１と接続端２１で接続されると共に、透析装置３と接続端２３で接続されている。本発明では、透析用配管２内の汚染を防止するために、透析用配管２に、透析用水供給装置1との接続端２１に近接してＵＦ膜４を設けると共に、透析装置３との接続端２３に近接してＵＦ膜５を設けている。その結果、透析用配管２内の汚染を防止することができるだけでなく、透析装置３内に設けたＵＦ膜の寿命を大幅に向上させることができ、ＵＦ膜を交換する手間が大幅に軽減された。 A method for preventing contamination in the dialysis pipe will be described with reference to FIG.
FIG. 1 is an explanatory diagram of a method for preventing contamination in a dialysis pipe of the present invention, and shows a single-pass dialysis water pipe.
The dialysis pipe 2 is connected to the dialysis water supply apparatus 1 at the connection end 21 and is connected to the dialysis apparatus 3 at the connection end 23. In the present invention, in order to prevent contamination in the dialysis pipe 2, the dialysis pipe 2 is provided with a UF membrane 4 in the vicinity of the connection end 21 to the dialysis water supply apparatus 1 and connected to the dialysis apparatus 3. A UF film 5 is provided in the vicinity of the end 23. As a result, not only can the contamination in the dialysis pipe 2 be prevented, but also the life of the UF membrane provided in the dialysis machine 3 can be greatly improved, and the labor for replacing the UF membrane is greatly reduced. It was.

１ 透析用水供給装置
２ 透析用配管
２１ 透析用水供給装置との接続端
２３ 透析装置との接続端
３ 透析装置
４ ＵＦ膜
５ ＵＦ膜 DESCRIPTION OF SYMBOLS 1 Dialysis water supply apparatus 2 Dialysis pipe 21 Connection end 23 with dialysis water supply apparatus Connection end 3 with dialysis apparatus 3 Dialysis apparatus 4 UF membrane 5 UF membrane

Claims (2)

透析用配管の透析用水供給装置（ＲＯ装置を含む）との接続端側に細菌やエンドトキシンを除去するためのフィルタを設けると共に、透析用配管の透析装置との接続端側に細菌やエンドトキシンを除去するためのフィルタを設けることを特徴とする、透析用配管内の汚染防止方法。 A filter for removing bacteria and endotoxin is installed on the end of the dialysis pipe connected to the dialysis water supply device (including the RO device), and bacteria and endotoxin are removed on the end of the dialysis pipe connected to the dialysis device. A method for preventing contamination in a dialysis pipe, characterized in that a filter is provided. フィルタを、透析用水供給装置との接続端および透析装置との接続端に近接して設ける、透析用配管内の汚染防止方法。 A method for preventing contamination in a dialysis pipe, wherein a filter is provided close to a connection end with a dialysis water supply device and a connection end with a dialysis device.
JP2010090728A 2010-04-09 2010-04-09 Contamination prevention method in dialysis piping Active JP5736661B2 (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10603424B2 (en) 2011-03-23 2020-03-31 Nxstage Medical, Inc. Peritoneal dialysis systems, devices, and methods
US11207454B2 (en) 2018-02-28 2021-12-28 Nxstage Medical, Inc. Fluid preparation and treatment devices methods and systems

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JPH0352296B2 (en) * 1983-03-01 1991-08-09 Sartorius Werke Gmbh
JPS61203973A (en) * 1984-12-07 1986-09-09 フレセニウス・ア−ゲ− Blood dialytic and filter apparatus
JP2001293471A (en) * 2000-04-14 2001-10-23 Mikuni Kikai Kk Purified water making device
JP2001353214A (en) * 2000-06-14 2001-12-25 Toray Medical Co Ltd Dialysis system
JP2004518462A (en) * 2000-10-19 2004-06-24 ネフロス・インコーポレーテッド Method and apparatus for producing a sterile infusion
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Cited By (14)

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Publication number Priority date Publication date Assignee Title
US11433170B2 (en) 2011-03-23 2022-09-06 Nxstage Medical, Inc. Dialysis systems, devices, and methods
US11690941B2 (en) 2011-03-23 2023-07-04 Nxstage Medical, Inc. Peritoneal dialysis systems, devices, and methods
US10688234B2 (en) 2011-03-23 2020-06-23 Nxstage Medical, Inc. Peritoneal dialysis systems, devices, and methods
US10688235B2 (en) 2011-03-23 2020-06-23 Nxstage Medical, Inc. Peritoneal dialysis systems, devices, and methods
US10898630B2 (en) 2011-03-23 2021-01-26 Nxstage Medical, Inc. Peritoneal dialysis systems, devices, and methods
US11135348B2 (en) 2011-03-23 2021-10-05 Nxstage Medical, Inc. Peritoneal dialysis systems, devices, and methods
US10610630B2 (en) 2011-03-23 2020-04-07 Nxstage Medical, Inc. Peritoneal dialysis systems, devices, and methods
US11224684B2 (en) 2011-03-23 2022-01-18 Nxstage Medical, Inc. Peritoneal dialysis systems, devices, and methods
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US10603424B2 (en) 2011-03-23 2020-03-31 Nxstage Medical, Inc. Peritoneal dialysis systems, devices, and methods
US11717601B2 (en) 2011-03-23 2023-08-08 Nxstage Medical, Inc. Dialysis systems, devices, and methods
US11207454B2 (en) 2018-02-28 2021-12-28 Nxstage Medical, Inc. Fluid preparation and treatment devices methods and systems
US11364328B2 (en) 2018-02-28 2022-06-21 Nxstage Medical, Inc. Fluid preparation and treatment devices methods and systems
US11872337B2 (en) 2018-02-28 2024-01-16 Nxstage Medical, Inc. Fluid preparation and treatment devices methods and systems

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