JP2011016804A5 - - Google Patents
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- Publication number
- JP2011016804A5 JP2011016804A5 JP2010161620A JP2010161620A JP2011016804A5 JP 2011016804 A5 JP2011016804 A5 JP 2011016804A5 JP 2010161620 A JP2010161620 A JP 2010161620A JP 2010161620 A JP2010161620 A JP 2010161620A JP 2011016804 A5 JP2011016804 A5 JP 2011016804A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- pharmaceutically acceptable
- acetyl
- pharmaceutical formulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 150000001875 compounds Chemical class 0.000 claims 14
- 208000036142 Viral infection Diseases 0.000 claims 4
- 230000009385 viral infection Effects 0.000 claims 4
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000006367 bivalent amino carbonyl group Chemical group [H]N([*:1])C([*:2])=O 0.000 claims 2
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- ZRALSGWEFCBTJO-UHFFFAOYSA-N guanidine group Chemical group NC(=N)N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 claims 2
- 125000002795 guanidino group Chemical group C(N)(=N)N* 0.000 claims 2
- 239000004615 ingredient Substances 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 230000000069 prophylactic effect Effects 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 claims 1
- UBCHPRBFMUDMNC-UHFFFAOYSA-N 1-(1-adamantyl)ethanamine Chemical compound C1C(C2)CC3CC2CC1(C(N)C)C3 UBCHPRBFMUDMNC-UHFFFAOYSA-N 0.000 claims 1
- 108010016626 Dipeptides Proteins 0.000 claims 1
- 208000005647 Mumps Diseases 0.000 claims 1
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 claims 1
- 208000010359 Newcastle Disease Diseases 0.000 claims 1
- 208000002606 Paramyxoviridae Infections Diseases 0.000 claims 1
- IWUCXVSUMQZMFG-AFCXAGJDSA-N Ribavirin Chemical compound N1=C(C(=O)N)N=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 IWUCXVSUMQZMFG-AFCXAGJDSA-N 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 238000005273 aeration Methods 0.000 claims 1
- DKNWSYNQZKUICI-UHFFFAOYSA-N amantadine Chemical compound C1C(C2)CC3CC2CC1(N)C3 DKNWSYNQZKUICI-UHFFFAOYSA-N 0.000 claims 1
- 229960003805 amantadine Drugs 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 239000003443 antiviral agent Substances 0.000 claims 1
- 125000006244 carboxylic acid protecting group Chemical group 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 206010022000 influenza Diseases 0.000 claims 1
- 239000000543 intermediate Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 208000010805 mumps infectious disease Diseases 0.000 claims 1
- VSZGPKBBMSAYNT-RRFJBIMHSA-N oseltamivir Chemical compound CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](N)C1 VSZGPKBBMSAYNT-RRFJBIMHSA-N 0.000 claims 1
- 229960003752 oseltamivir Drugs 0.000 claims 1
- 239000008177 pharmaceutical agent Substances 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 210000002345 respiratory system Anatomy 0.000 claims 1
- 229960000329 ribavirin Drugs 0.000 claims 1
- HZCAHMRRMINHDJ-DBRKOABJSA-N ribavirin Natural products O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1N=CN=C1 HZCAHMRRMINHDJ-DBRKOABJSA-N 0.000 claims 1
- 229960000888 rimantadine Drugs 0.000 claims 1
- 125000004044 trifluoroacetyl group Chemical group FC(C(=O)*)(F)F 0.000 claims 1
- 241000712461 unidentified influenza virus Species 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
- 229960001028 zanamivir Drugs 0.000 claims 1
- ARAIBEBZBOPLMB-UFGQHTETSA-N zanamivir Chemical compound CC(=O)N[C@@H]1[C@@H](N=C(N)N)C=C(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO ARAIBEBZBOPLMB-UFGQHTETSA-N 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPR8794A AUPR879401A0 (en) | 2001-11-09 | 2001-11-09 | Novel chemical compounds and their use |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003542183A Division JP2005508989A (ja) | 2001-11-09 | 2002-11-08 | 二量体化合物および抗ウイルス薬としてのそれらの使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011016804A JP2011016804A (ja) | 2011-01-27 |
| JP2011016804A5 true JP2011016804A5 (enExample) | 2011-10-20 |
Family
ID=3832613
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003542183A Pending JP2005508989A (ja) | 2001-11-09 | 2002-11-08 | 二量体化合物および抗ウイルス薬としてのそれらの使用 |
| JP2010161620A Withdrawn JP2011016804A (ja) | 2001-11-09 | 2010-07-16 | 二量体化合物および抗ウイルス薬としてのそれらの使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003542183A Pending JP2005508989A (ja) | 2001-11-09 | 2002-11-08 | 二量体化合物および抗ウイルス薬としてのそれらの使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US7223790B2 (enExample) |
| EP (1) | EP1451181B1 (enExample) |
| JP (2) | JP2005508989A (enExample) |
| KR (1) | KR101002794B1 (enExample) |
| CN (1) | CN100526309C (enExample) |
| AT (1) | ATE399780T1 (enExample) |
| AU (1) | AUPR879401A0 (enExample) |
| CA (1) | CA2463865C (enExample) |
| DE (1) | DE60227409D1 (enExample) |
| DK (1) | DK1451181T3 (enExample) |
| ES (1) | ES2307793T3 (enExample) |
| PT (1) | PT1451181E (enExample) |
| WO (1) | WO2003040137A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4535713B2 (ja) * | 2003-10-30 | 2010-09-01 | 株式会社ヤクルト本社 | 抗ヒトサイトメガロウイルス剤 |
| US20070094334A1 (en) * | 2005-10-21 | 2007-04-26 | Microsoft Corporation | Service/client synchronization |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9516276D0 (en) * | 1995-08-08 | 1995-10-11 | Biota Scient Management | Chemical compounds |
| KR19990087449A (ko) * | 1996-03-01 | 1999-12-27 | 리차드 웨드레이 | 인플루엔자 바이러스의 검출방법 및 이에 이용되는 화합물 |
| TR199901081T2 (xx) | 1996-11-14 | 1999-08-23 | Biota Scientific Management Pty.Ltd. | Y�ntem ve bu y�ntemde kullan�lan yeni bile�imler. |
| AUPP913999A0 (en) * | 1999-03-12 | 1999-04-01 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
| AUPR001000A0 (en) | 2000-09-08 | 2000-10-05 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
-
2001
- 2001-11-09 AU AUPR8794A patent/AUPR879401A0/en not_active Abandoned
-
2002
- 2002-11-08 DK DK02771913T patent/DK1451181T3/da active
- 2002-11-08 JP JP2003542183A patent/JP2005508989A/ja active Pending
- 2002-11-08 DE DE60227409T patent/DE60227409D1/de not_active Expired - Lifetime
- 2002-11-08 ES ES02771913T patent/ES2307793T3/es not_active Expired - Lifetime
- 2002-11-08 AT AT02771913T patent/ATE399780T1/de not_active IP Right Cessation
- 2002-11-08 EP EP02771913A patent/EP1451181B1/en not_active Expired - Lifetime
- 2002-11-08 KR KR1020047006447A patent/KR101002794B1/ko not_active Expired - Fee Related
- 2002-11-08 WO PCT/AU2002/001527 patent/WO2003040137A1/en not_active Ceased
- 2002-11-08 CA CA2463865A patent/CA2463865C/en not_active Expired - Fee Related
- 2002-11-08 CN CNB028222482A patent/CN100526309C/zh not_active Expired - Fee Related
- 2002-11-08 US US10/494,260 patent/US7223790B2/en not_active Expired - Fee Related
- 2002-11-08 PT PT02771913T patent/PT1451181E/pt unknown
-
2007
- 2007-04-12 US US11/734,394 patent/US7468388B2/en not_active Expired - Fee Related
-
2010
- 2010-07-16 JP JP2010161620A patent/JP2011016804A/ja not_active Withdrawn
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