JP2010539893A5 - - Google Patents

Download PDF

Info

Publication number
JP2010539893A5
JP2010539893A5 JP2010525273A JP2010525273A JP2010539893A5 JP 2010539893 A5 JP2010539893 A5 JP 2010539893A5 JP 2010525273 A JP2010525273 A JP 2010525273A JP 2010525273 A JP2010525273 A JP 2010525273A JP 2010539893 A5 JP2010539893 A5 JP 2010539893A5
Authority
JP
Japan
Prior art keywords
stretch
nucleic acid
acid according
nucleotides
box
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010525273A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010539893A (ja
JP5798320B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2008/008097 external-priority patent/WO2009040113A2/en
Publication of JP2010539893A publication Critical patent/JP2010539893A/ja
Publication of JP2010539893A5 publication Critical patent/JP2010539893A5/ja
Application granted granted Critical
Publication of JP5798320B2 publication Critical patent/JP5798320B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2010525273A 2007-09-24 2008-09-24 C5aに結合する核酸 Expired - Fee Related JP5798320B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07018750.5 2007-09-24
EP07018750 2007-09-24
PCT/EP2008/008097 WO2009040113A2 (en) 2007-09-24 2008-09-24 C5a BINDING NUCLEIC ACIDS

Publications (3)

Publication Number Publication Date
JP2010539893A JP2010539893A (ja) 2010-12-24
JP2010539893A5 true JP2010539893A5 (https=) 2011-11-04
JP5798320B2 JP5798320B2 (ja) 2015-10-21

Family

ID=40174751

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010525273A Expired - Fee Related JP5798320B2 (ja) 2007-09-24 2008-09-24 C5aに結合する核酸

Country Status (11)

Country Link
US (1) US8507456B2 (https=)
EP (2) EP2205734A2 (https=)
JP (1) JP5798320B2 (https=)
KR (1) KR20100072185A (https=)
CN (1) CN101809154A (https=)
AU (1) AU2008303775A1 (https=)
BR (1) BRPI0817260A2 (https=)
CA (1) CA2700441A1 (https=)
MX (1) MX2010003109A (https=)
RU (1) RU2010116245A (https=)
WO (1) WO2009040113A2 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8066757B2 (en) 2007-10-17 2011-11-29 Mindframe, Inc. Blood flow restoration and thrombus management methods
WO2010108657A2 (en) * 2009-03-23 2010-09-30 Noxxon Pharma Ag C5a binding nucleic acids and the use thereof
CN102597775A (zh) * 2009-09-25 2012-07-18 佐马技术有限公司 筛选方法
KR20140044324A (ko) * 2011-04-26 2014-04-14 레가도 바이오사이언스, 인코포레이티드 페길화된 올리고뉴클레오티드의 제조방법
EP2718866B1 (en) 2011-06-07 2020-09-09 Koninklijke Philips N.V. Providing nucleotide sequence data
US10531655B2 (en) 2011-12-02 2020-01-14 The Regents Of The University Of California Reperfusion protection solution and uses thereof
WO2013104540A1 (en) * 2012-01-10 2013-07-18 Noxxon Pharma Ag New c5a binding nucleic acids
WO2015066027A2 (en) 2013-10-28 2015-05-07 Dots Devices, Inc. Allergen detection
WO2015103438A2 (en) 2014-01-02 2015-07-09 Genelux Corporation Oncolytic virus adjunct therapy with agents that increase virus infectivity
CN106860867A (zh) * 2017-02-23 2017-06-20 中山大学 己糖激酶2特异性抑制剂在急性中枢神经系统损伤疾病中的应用
EP3553521A1 (en) * 2018-04-12 2019-10-16 Koninklijke Philips N.V. Gingivitis diagnostic methods, uses and kits
WO2025196240A1 (en) 2024-03-20 2025-09-25 Aptarion Biotech Ag Method of treating a disorder with a c5a inhibitor
EP4620474A1 (en) 2024-03-20 2025-09-24 APTARION biotech AG Method of treating a disorder with a c5a inhibitor

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6011020A (en) 1990-06-11 2000-01-04 Nexstar Pharmaceuticals, Inc. Nucleic acid ligand complexes
US6395888B1 (en) * 1996-02-01 2002-05-28 Gilead Sciences, Inc. High affinity nucleic acid ligands of complement system proteins
US6395029B1 (en) 1999-01-19 2002-05-28 The Children's Hospital Of Philadelphia Sustained delivery of polyionic bioactive agents
US6652886B2 (en) 2001-02-16 2003-11-25 Expression Genetics Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents
EP1306382A1 (de) 2001-10-26 2003-05-02 Noxxon Pharma AG Modifizierte L-Nukleinsäure
WO2003070823A2 (en) 2002-02-20 2003-08-28 The General Hospital Corporation Conjugates comprising a biodegradable polymer and uses therefor
MXPA05011022A (es) 2003-04-13 2006-04-27 Enzon Pharmaceuticals Inc Profarmacos oligonucleotidos polimericos.
GB0314472D0 (en) 2003-06-20 2003-07-23 Warwick Effect Polymers Ltd Polymer
US20070116710A1 (en) * 2004-02-03 2007-05-24 Leonard Bell Methods of treating hemolytic anemia
US20090281296A1 (en) 2004-02-09 2009-11-12 Supramol Parenteral Colloid Gmbh Process for the production of conjugates from polysaccharides and polynucelotides
PL3385384T3 (pl) 2004-02-12 2021-03-08 Archemix Llc Aptamerowe środki terapeutyczne użyteczne w leczeniu zaburzeń powiązanych z dopełniaczem
US7803931B2 (en) 2004-02-12 2010-09-28 Archemix Corp. Aptamer therapeutics useful in the treatment of complement-related disorders
MXPA06010782A (es) 2004-03-23 2007-03-28 Complex Biosystems Gmbh Ligador de profarmaco.
CN101098703B (zh) 2004-11-05 2011-08-03 费城儿童医院 用于分子治疗的生物降解连接剂
KR101584468B1 (ko) * 2006-03-08 2016-01-13 아케믹스 엘엘씨 안질환의 치료에 유용한 보체 결합 앱타머 및 항-c5 제제
JP2010503707A (ja) 2006-09-15 2010-02-04 エンゾン ファーマスーティカルズ インコーポレイテッド オリゴヌクレオチドの送達を目的としたヒンダードエステル系生体分解性リンカー
WO2008052774A2 (en) 2006-10-31 2008-05-08 Noxxon Pharma Ag Methods for detection of a single- or double-stranded nucleic acid molecule
WO2010108657A2 (en) * 2009-03-23 2010-09-30 Noxxon Pharma Ag C5a binding nucleic acids and the use thereof

Similar Documents

Publication Publication Date Title
JP2010539893A5 (https=)
RU2010116245A (ru) НУКЛЕИНОВЫЕ КИСЛОТЫ, СВЯЗЫВАЮЩИЕ C5a
US12070458B2 (en) Therapeutic agent composition and method of use, for treatment of mild congnitive impairment, depression, and psychological disorders
Gombert et al. Outcome of elective and emergency open thoraco-abdominal aortic aneurysm repair in 255 cases: a retrospective single centre study
CA2663072C (en) Expansion method for adult stem cells from blood, particularly peripheral blood, and relative application in medical field
TW201134482A (en) Aptamers to β -NGF and their use in treating β -NGF mediated diseases and disorders
JP2010504083A5 (https=)
US11565002B2 (en) Thrombus imaging aptamers and methods of using same
JP6640725B2 (ja) spadinのレトロ−インベルソ類似体は増大された抗うつ作用を示す
Muchtar et al. Supportive care for systemic amyloidosis: International Society of Amyloidosis (ISA) expert panel guidelines
US20150335612A1 (en) Artemisinin And Its Derivatives For Use In The Treatment Of Kidney Disease
CN103805563B (zh) 一种脑靶向干细胞及其制备方法和应用
WO2019006692A1 (zh) 用于治疗、改善或预防神经系统相关病症的化合物及其用途
CN112121042A (zh) Pso用于制备抗败血症及其诱发的心肌损伤药物的应用
CN119390854A (zh) 一种多肽Tat-CIRP及其应用
WO2017147044A1 (en) Peptides and methods for treatment of neurodegenerative diseases
ES2546094T3 (es) Antagonistas contra la interacción de PF4 y RANTES
Kar et al. Anesthesia management of renal transplantation: an update
US20250177479A1 (en) Depsipeptide-based amphiphilic buliding block to inhibit protein-protein interactions, nanostructure comprised thereof and uses thereof
EP4522191A1 (en) Agents inducing vascularisation
Bozan et al. The diagnostic efficacy of some ischemic markers (urotensin II and urotensin II related peptide) in early diagnosis of intestinal ischemia in experimentally increased intraabdominal pressure in rats
WO2026056035A1 (zh) 一种具有神经保护功能的含脒基新型iNOS抑制剂及其制备方法与应用
JP4582561B2 (ja) 移植による血管病変の発生抑制剤
Shi et al. Development of Oxytocin-and Vasopressin-Network in the Supraoptic and Paraventricular Nuclei of Fetal Sheep
CN121868277A (zh) Slco5a1在制备用于治疗和/或预防心力衰竭药物中的应用