JP2010535520A - Ｅｇｆｒ阻害因子治療のための予測マーカー - Google Patents

Ｅｇｆｒ阻害因子治療のための予測マーカー Download PDF

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Publication number
JP2010535520A
JP2010535520A JP2010520467A JP2010520467A JP2010535520A JP 2010535520 A JP2010535520 A JP 2010535520A JP 2010520467 A JP2010520467 A JP 2010520467A JP 2010520467 A JP2010520467 A JP 2010520467A JP 2010535520 A JP2010535520 A JP 2010535520A
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JP
Japan
Prior art keywords
patients
patient
cancer
analysis
treatment
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Pending
Application number
JP2010520467A
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English (en)
Japanese (ja)
Inventor
デルマー，ポール
クルクハンマー，バーバラ
ルッツ，フェレナ
マクローリン，パトリシア
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JP2010535520A publication Critical patent/JP2010535520A/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
JP2010520467A 2007-08-14 2008-08-07 Ｅｇｆｒ阻害因子治療のための予測マーカー Pending JP2010535520A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07114305 2007-08-14
PCT/EP2008/006518 WO2009021679A1 (en) 2007-08-14 2008-08-07 Predictive marker for egfr inhibitor treamtent

Publications (1)

Publication Number Publication Date
JP2010535520A true JP2010535520A (ja) 2010-11-25

Family

ID=39789783

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010520467A Pending JP2010535520A (ja) 2007-08-14 2008-08-07 Ｅｇｆｒ阻害因子治療のための予測マーカー

Country Status (9)

Country Link
EP (1) EP2176429A1 (de)
JP (1) JP2010535520A (de)
KR (1) KR20100037633A (de)
CN (1) CN101802221A (de)
AU (1) AU2008286412A1 (de)
BR (1) BRPI0815372A2 (de)
CA (1) CA2695318A1 (de)
MX (1) MX2010001572A (de)
WO (1) WO2009021679A1 (de)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006526420A (ja) * 2003-05-30 2006-11-24 アストラゼネカ ユーケー リミテッド プロセス

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646249A (en) * 1994-02-28 1997-07-08 The United States Of America As Represented By The Department Of Health And Human Services Isolation and characterization of a novel chaperone protein
WO2004111273A2 (en) * 2003-05-30 2004-12-23 Genomic Health, Inc. Gene expression markers for response to egfr inhibitor drugs

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006526420A (ja) * 2003-05-30 2006-11-24 アストラゼネカ ユーケー リミテッド プロセス

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6012041274; Ｈｕｍ．　Ｍｏｌ．　Ｇｅｎｅｔ．，　（２００４），　１３，　［２４］，　ｐ．３０２９-３０４３ *
JPN6012041275; ［ＨＧ-Ｕ１３３Ａ］　Ａｆｆｙｍｅｔｒｉｘ　Ｈｕｍａｎ　Ｇｅｎｏｍｅ　Ｕ１３３Ａ　Ａｒｒａｙ．　［ｏｎｌｉｎｅ］．　２００２-ＭＡＲ-１１　ｕｐｌｏａｄｅｄ．　［Ｒｅｔｒｉｅｖｅｄ　ｏｎ　２０１２-Ａ *

Also Published As

Publication number Publication date
WO2009021679A1 (en) 2009-02-19
BRPI0815372A2 (pt) 2019-09-24
MX2010001572A (es) 2010-03-15
CA2695318A1 (en) 2009-02-19
CN101802221A (zh) 2010-08-11
EP2176429A1 (de) 2010-04-21
AU2008286412A1 (en) 2009-02-19
KR20100037633A (ko) 2010-04-09

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