JP2010534243A - Ｃｄ２００に対する抗体および免疫応答への使用 - Google Patents
Ｃｄ２００に対する抗体および免疫応答への使用 Download PDFInfo
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- A—HUMAN NECESSITIES
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
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| PCT/US2008/009037 WO2009014745A1 (en) | 2007-07-25 | 2008-07-25 | Antibodies to cd200 and uses thereof in inhibiting immune responses |
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| JP2015135830A Pending JP2015172090A (ja) | 2007-07-25 | 2015-07-07 | Ｃｄ２００に対する抗体および免疫応答への使用 |
| JP2016052050A Pending JP2016117762A (ja) | 2007-07-25 | 2016-03-16 | Ｃｄ２００に対する抗体および免疫応答への使用 |
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| JP2016052050A Pending JP2016117762A (ja) | 2007-07-25 | 2016-03-16 | Ｃｄ２００に対する抗体および免疫応答への使用 |
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| EP (1) | EP2178561A1 (enExample) |
| JP (4) | JP2010534243A (enExample) |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013163695A (ja) * | 2007-07-25 | 2013-08-22 | Alexion Pharmaceuticals Inc | Ｃｄ２００に対する抗体および免疫応答への使用 |
| JP2014505706A (ja) * | 2011-02-03 | 2014-03-06 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | 同種移植片の生存を長期化するための抗ｃｄ２００抗体の使用 |
| JP2018504104A (ja) * | 2014-12-17 | 2018-02-15 | セレクティスＣｅｌｌｅｃｔｉｓ | 非Ｔ細胞伝達ドメインを発現する阻害性キメラ抗原受容体（ｉＣＡＲまたはＮ−ＣＡＲ） |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
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| MX2012009321A (es) * | 2010-02-11 | 2012-11-21 | Alexion Pharma Inc | Metodos terapeuticos que utilizan anticuerpos anti-cd200. |
| EP3150632B1 (en) | 2011-06-10 | 2020-04-08 | Her Majesty The Queen in right of Canada, as represented by the Minister of National Defence | Anti-ricin antibodies and uses thereof |
| ES2758884T3 (es) | 2011-06-24 | 2020-05-06 | Stephen D Gillies | Proteínas de fusión de inmunoglobulina a través de cadena ligera y métodos de uso de ellas |
| US9737598B2 (en) * | 2014-06-30 | 2017-08-22 | Regents Of The University Of Minnesota | CD200 inhibitors and methods of use thereof |
| US10888609B2 (en) | 2015-11-03 | 2021-01-12 | Regents Of The University Of Minnesota | CD200 inhibitors and methods of use thereof |
| BR112018076260A2 (pt) | 2016-06-20 | 2019-03-26 | Kymab Limited | anticorpo ou fragmento do mesmo que se liga especificamente a hpd-l1, anticorpo biespecífico ou proteína de fusão, uso de um anticorpo ou fragmento, método, composição farmacêutica, método de modulação, método de inibição, método de tratamento, ácido nucleico, vetor, hospedeiro e imunocitocina |
| WO2018102594A1 (en) * | 2016-12-01 | 2018-06-07 | Alexion Pharmaceuticals, Inc. | Methods of treating solid tumors with anti-cd200 antibodies |
| KR101968246B1 (ko) * | 2017-04-27 | 2019-04-11 | 서울대학교산학협력단 | 이종 각막 이식에서 항 cd20 단일클론항체 및 타클로리무스의 복합면역억제 방법 |
| WO2019067499A1 (en) | 2017-09-27 | 2019-04-04 | Alexion Pharmaceuticals, Inc. | BIOMARKER SIGNATURE FOR PREDICTING A TUMOR RESPONSE TO ANTI-CD200 THERAPY |
| WO2019126133A1 (en) | 2017-12-20 | 2019-06-27 | Alexion Pharmaceuticals, Inc. | Liquid formulations of anti-cd200 antibodies |
| US11802154B2 (en) | 2017-12-20 | 2023-10-31 | Alexion Pharmaceuticals, Inc. | Humanized anti-CD200 antibodies and uses thereof |
| EP3911357A1 (en) | 2019-01-14 | 2021-11-24 | Regents of the University of Minnesota | Cd200ar ligands for cancer immunotherapy |
| EP4296280A1 (en) * | 2022-06-21 | 2023-12-27 | F. Hoffmann-La Roche AG | Cd123 and cd200 as markers for the diagnosis and immune-eradication of leukemic stem cells (lscs) |
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|---|---|---|---|---|
| US7223729B2 (en) * | 1997-11-07 | 2007-05-29 | Trillium Therapeutics Inc. | Methods of treating allergy by administering a CD200 protein |
| DK1032662T3 (da) * | 1997-11-07 | 2006-07-03 | Trillium Therapeutics Inc | Fremgangsmåder og sammensætninger til immunmodulation |
| US20060057651A1 (en) * | 2000-12-08 | 2006-03-16 | Bowdish Katherine S | Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof |
| WO2004060295A2 (en) | 2002-12-27 | 2004-07-22 | Schering Corporation | Methods of inducing and maintaining immune tolerance |
| NZ599035A (en) * | 2006-01-12 | 2013-12-20 | Alexion Pharma Inc | Antibodies to ox-2/cd200 and uses thereof |
| CA2694121C (en) | 2007-07-25 | 2016-06-07 | Alexion Pharmaceuticals, Inc. | Methods and compositions for treating autoimmune disease |
| JP2010534243A (ja) | 2007-07-25 | 2010-11-04 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | Ｃｄ２００に対する抗体および免疫応答への使用 |
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2008
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- 2008-07-25 WO PCT/US2008/009037 patent/WO2009014745A1/en not_active Ceased
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2012
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2013
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2015
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2016
- 2016-03-16 JP JP2016052050A patent/JP2016117762A/ja active Pending
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| EUROPEAN JOURNAL OF IMMUNOLOGY, vol. 31, no. 8, JPN6013004075, 2001, pages 2331 - 2337, ISSN: 0002445683 * |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013163695A (ja) * | 2007-07-25 | 2013-08-22 | Alexion Pharmaceuticals Inc | Ｃｄ２００に対する抗体および免疫応答への使用 |
| JP2014505706A (ja) * | 2011-02-03 | 2014-03-06 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | 同種移植片の生存を長期化するための抗ｃｄ２００抗体の使用 |
| JP2018504104A (ja) * | 2014-12-17 | 2018-02-15 | セレクティスＣｅｌｌｅｃｔｉｓ | 非Ｔ細胞伝達ドメインを発現する阻害性キメラ抗原受容体（ｉＣＡＲまたはＮ−ＣＡＲ） |
Also Published As
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|---|---|
| US20100291085A1 (en) | 2010-11-18 |
| USRE46323E1 (en) | 2017-02-28 |
| US8637014B2 (en) | 2014-01-28 |
| WO2009014745A1 (en) | 2009-01-29 |
| US8252285B2 (en) | 2012-08-28 |
| CA2697159A1 (en) | 2009-01-29 |
| JP5926702B2 (ja) | 2016-05-25 |
| AU2008279619B2 (en) | 2013-11-14 |
| JP2016117762A (ja) | 2016-06-30 |
| BRPI0814644A2 (pt) | 2015-01-27 |
| KR20100041849A (ko) | 2010-04-22 |
| CA2697159C (en) | 2017-02-14 |
| EP2178561A1 (en) | 2010-04-28 |
| AU2008279619A1 (en) | 2009-01-29 |
| US20120321625A1 (en) | 2012-12-20 |
| JP2013163695A (ja) | 2013-08-22 |
| JP2015172090A (ja) | 2015-10-01 |
| MX2010000981A (es) | 2010-05-21 |
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