JP2010532986A5 - - Google Patents
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- Publication number
- JP2010532986A5 JP2010532986A5 JP2010515596A JP2010515596A JP2010532986A5 JP 2010532986 A5 JP2010532986 A5 JP 2010532986A5 JP 2010515596 A JP2010515596 A JP 2010515596A JP 2010515596 A JP2010515596 A JP 2010515596A JP 2010532986 A5 JP2010532986 A5 JP 2010532986A5
- Authority
- JP
- Japan
- Prior art keywords
- nad
- sample
- nucleic acid
- dependent ligase
- acid molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000003960 Ligases Human genes 0.000 claims 48
- 108090000364 Ligases Proteins 0.000 claims 48
- 230000001419 dependent effect Effects 0.000 claims 44
- 150000007523 nucleic acids Chemical class 0.000 claims 33
- 102000039446 nucleic acids Human genes 0.000 claims 33
- 108020004707 nucleic acids Proteins 0.000 claims 33
- 241000894006 Bacteria Species 0.000 claims 24
- 230000000694 effects Effects 0.000 claims 24
- 238000000034 method Methods 0.000 claims 24
- 239000000758 substrate Substances 0.000 claims 20
- 244000005700 microbiome Species 0.000 claims 13
- 230000001580 bacterial effect Effects 0.000 claims 11
- 239000003795 chemical substances by application Substances 0.000 claims 7
- 239000003242 anti bacterial agent Substances 0.000 claims 6
- 210000004027 cell Anatomy 0.000 claims 6
- 108090000988 Lysostaphin Proteins 0.000 claims 4
- 101710163270 Nuclease Proteins 0.000 claims 4
- 238000002360 preparation method Methods 0.000 claims 4
- 210000002421 cell wall Anatomy 0.000 claims 3
- 239000000356 contaminant Substances 0.000 claims 3
- 230000009089 cytolysis Effects 0.000 claims 3
- 238000011534 incubation Methods 0.000 claims 3
- 230000003834 intracellular effect Effects 0.000 claims 3
- 239000000463 material Substances 0.000 claims 3
- 230000035699 permeability Effects 0.000 claims 3
- 239000013543 active substance Substances 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 238000011109 contamination Methods 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 238000012216 screening Methods 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 230000006037 cell lysis Effects 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 claims 1
- 230000003100 immobilizing effect Effects 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 230000002147 killing effect Effects 0.000 claims 1
- 108010072532 lysostaphin endopeptidase Proteins 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 230000002829 reductive effect Effects 0.000 claims 1
- 238000011895 specific detection Methods 0.000 claims 1
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0713255A GB0713255D0 (en) | 2007-07-09 | 2007-07-09 | Improved methods and kits for detecting an enzyme capable of modifying a nucleic acid |
| GB0713972A GB0713972D0 (en) | 2007-07-09 | 2007-07-18 | Improved methods and kits for detecting an enzyme capable of modifying a nucleic acid |
| GB0719785A GB0719785D0 (en) | 2007-07-09 | 2007-10-10 | Improved detection of micro-organisms |
| GB0802857A GB0802857D0 (en) | 2008-02-15 | 2008-02-15 | Improved bacterial detection methods and kits |
| GB0807054A GB0807054D0 (en) | 2008-04-17 | 2008-04-17 | Improved detection of micro-organisms |
| PCT/GB2008/002354 WO2009007719A2 (en) | 2007-07-09 | 2008-07-09 | Detection of micro-organisms based on their nad-dependent dna ligase activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010532986A JP2010532986A (ja) | 2010-10-21 |
| JP2010532986A5 true JP2010532986A5 (https=) | 2011-09-01 |
Family
ID=39790901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010515596A Pending JP2010532986A (ja) | 2007-07-09 | 2008-07-09 | 改良された微生物の検出 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20100291564A1 (https=) |
| EP (1) | EP2179052B1 (https=) |
| JP (1) | JP2010532986A (https=) |
| CN (1) | CN101849019A (https=) |
| AU (1) | AU2008273946A1 (https=) |
| CA (1) | CA2692800A1 (https=) |
| MX (1) | MX2010000031A (https=) |
| WO (1) | WO2009007719A2 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0906643D0 (en) | 2009-04-17 | 2009-06-03 | Wilson Stuart M | Detection of bacteria and fungi |
| KR102068136B1 (ko) | 2010-04-16 | 2020-01-20 | 모멘텀 바이오사이언스, 리미티드 | 비-정제된 샘플에서 세포 생존력을 결정하는데에 유용한 효소 활성을 측정하기 위한 방법 |
| KR20150005511A (ko) | 2012-01-05 | 2015-01-14 | 제우스 사이언티픽, 아이엔씨. | 개선된 dna 중합효소 활성 분석 및 생육성 미생물의 검출을 가능하게 하는 방법 |
| JP2015513921A (ja) * | 2012-04-12 | 2015-05-18 | ゼウス サイエンティフィック、インク． | 任意のポリメラーゼ伸長活性の高感度定量的測定と生細胞存在の決定とに有用なポリメラーゼ活性測定方法 |
| GB2528647A (en) * | 2014-07-10 | 2016-02-03 | Momentum Bioscience Ltd | Detecting viable microorganisms |
| CN108449942A (zh) * | 2015-05-01 | 2018-08-24 | 微生物发现集团有限责任公司 | 核酸检测和定量方法以及组合物 |
| US12157690B2 (en) | 2015-12-09 | 2024-12-03 | Microbial Discovery Group Llc | Cold temperature-resistant microbials and methods of their use |
| CA3016203C (en) | 2016-02-29 | 2024-06-11 | Microbial Discovery Group, Llc | Direct-fed microbials |
| WO2017182775A1 (en) * | 2016-04-18 | 2017-10-26 | Momentum Bioscience Limited | Microorganism detection involving filtration |
| US20200354767A1 (en) * | 2017-11-16 | 2020-11-12 | The Regents Of The University Of Colorado, A Body Corporate | Methods to measure functional heterogeneity among single cells |
| EP3749775B1 (en) * | 2018-02-07 | 2023-06-07 | Mycometer A/S | Improved method for measurement of microbial biomass |
| GB201805479D0 (en) | 2018-04-03 | 2018-05-16 | Momentum Bioscience Ltd | Microorganism separation and detection |
| WO2020072578A1 (en) | 2018-10-02 | 2020-04-09 | Microbial Discovery Group, Llc | Microbials for animals |
| CN111118181B (zh) * | 2018-10-31 | 2023-05-12 | 华东师范大学 | 一种细菌的检测方法 |
| CN114929027A (zh) | 2019-08-22 | 2022-08-19 | 微生物发现集团有限责任公司 | 用微生物菌株和抗生素的抑制方法 |
| GB201914538D0 (en) | 2019-10-08 | 2019-11-20 | Momentum Bioscience Ltd | Microorganism capture from antimicrobial-containing solution |
| BR112023002974A2 (pt) | 2020-08-21 | 2023-04-04 | Microbial Discovery Group Llc | Cepas microbianas e antibióticos |
| US12514885B2 (en) | 2020-08-21 | 2026-01-06 | Microbial Discovery Group, Llc | Microbials and antibiotics |
| GB202405229D0 (en) | 2024-04-12 | 2024-05-29 | Momentum Bioscience Ltd | Microorganism enumeration |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4437975A (en) | 1977-07-20 | 1984-03-20 | Mobil Oil Corporation | Manufacture of lube base stock oil |
| US4931390A (en) * | 1986-04-16 | 1990-06-05 | Public Health Research Institute Of The City Of New York, Inc. | Expression of the cloned lysostaphin gene |
| CA1340843C (en) | 1987-07-31 | 1999-12-07 | J. Lawrence Burg | Selective amplification of target polynucleotide sequences |
| CA2005589C (en) | 1988-12-16 | 2001-02-06 | Akzo Nobel Nv | Self-sustained, sequence replication system |
| DE4033752A1 (de) * | 1990-10-24 | 1992-04-30 | Reissbrodt Rolf Dr Sc Nat | Verfahren zur herstellung von lysostaphin |
| US5976806A (en) * | 1997-06-25 | 1999-11-02 | Pioneer Hi-Bred International, Inc. | DNA ligase assay |
| JP3267576B2 (ja) | 1998-11-09 | 2002-03-18 | 三光純薬株式会社 | プローブ高分子の形成方法 |
| MXPA02003885A (es) * | 1999-10-19 | 2005-06-03 | Bharat Biotech International L | Expresion de lisostafina madura recombinante. |
| US6558907B2 (en) * | 2001-05-16 | 2003-05-06 | Corning Incorporated | Methods and compositions for arraying nucleic acids onto a solid support |
| WO2004067726A2 (en) | 2003-01-29 | 2004-08-12 | Keck Graduate Institute | Isothermal reactions for the amplification of oligonucleotides |
| JP2006526399A (ja) * | 2003-06-02 | 2006-11-24 | チェック−ポインツ ホールディング ベー．フェー． | 食物サンプル中の微生物を高速に検出する方法 |
| GB0324650D0 (en) * | 2003-10-22 | 2003-11-26 | Acolyte Biomedica Ltd | Using nucleic acids for clinical microbiology testing |
| US20070264680A1 (en) * | 2004-03-22 | 2007-11-15 | Proteus S.A. | Method and Test-Kit for the Detection and Quantification of Organisms |
| US20070009944A1 (en) * | 2005-07-01 | 2007-01-11 | University Of East Anglia | Assay for nucleic acid ligase and nucleic acid nuclease |
-
2008
- 2008-07-09 CA CA 2692800 patent/CA2692800A1/en not_active Abandoned
- 2008-07-09 US US12/667,818 patent/US20100291564A1/en not_active Abandoned
- 2008-07-09 JP JP2010515596A patent/JP2010532986A/ja active Pending
- 2008-07-09 WO PCT/GB2008/002354 patent/WO2009007719A2/en not_active Ceased
- 2008-07-09 AU AU2008273946A patent/AU2008273946A1/en not_active Abandoned
- 2008-07-09 EP EP08775898A patent/EP2179052B1/en not_active Not-in-force
- 2008-07-09 MX MX2010000031A patent/MX2010000031A/es active IP Right Grant
- 2008-07-09 CN CN200880104327A patent/CN101849019A/zh active Pending
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