JP2010520757A5 - - Google Patents

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Publication number
JP2010520757A5
JP2010520757A5 JP2009552911A JP2009552911A JP2010520757A5 JP 2010520757 A5 JP2010520757 A5 JP 2010520757A5 JP 2009552911 A JP2009552911 A JP 2009552911A JP 2009552911 A JP2009552911 A JP 2009552911A JP 2010520757 A5 JP2010520757 A5 JP 2010520757A5
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JP
Japan
Prior art keywords
region
cell
retroviral construct
coding region
ltr
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JP2009552911A
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English (en)
Japanese (ja)
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JP2010520757A (ja
JP5399927B2 (ja
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Priority claimed from US11/683,962 external-priority patent/US7737124B2/en
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Publication of JP2010520757A publication Critical patent/JP2010520757A/ja
Publication of JP2010520757A5 publication Critical patent/JP2010520757A5/ja
Application granted granted Critical
Publication of JP5399927B2 publication Critical patent/JP5399927B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2009552911A 2007-03-08 2008-03-07 細胞内で細胞毒性を低減して抗ウイルス性小ｒｎａ分子を発現させる方法 Expired - Fee Related JP5399927B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/683,962 US7737124B2 (en) 2001-09-13 2007-03-08 Method for expression of small antiviral RNA molecules with reduced cytotoxicity within a cell
US11/683,962 2007-03-08
PCT/US2008/056245 WO2008109837A2 (en) 2007-03-08 2008-03-07 Method for expression of small antiviral rna molecules with reduced cytotoxicity within a cell

Publications (3)

Publication Number Publication Date
JP2010520757A JP2010520757A (ja) 2010-06-17
JP2010520757A5 true JP2010520757A5 (enExample) 2011-04-21
JP5399927B2 JP5399927B2 (ja) 2014-01-29

Family

ID=39816837

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009552911A Expired - Fee Related JP5399927B2 (ja) 2007-03-08 2008-03-07 細胞内で細胞毒性を低減して抗ウイルス性小ｒｎａ分子を発現させる方法

Country Status (6)

Country Link
US (6) US7737124B2 (enExample)
EP (1) EP2115164B1 (enExample)
JP (1) JP5399927B2 (enExample)
AU (1) AU2008222663B2 (enExample)
CA (2) CA3012986A1 (enExample)
WO (1) WO2008109837A2 (enExample)

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AU2002326906C1 (en) * 2001-09-13 2009-01-29 California Institute Of Technology Method for expression of small antiviral RNA molecules within a cell
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EP2166107A1 (en) * 2008-09-12 2010-03-24 TaconicArtemis GmbH Lentiviral vectors for the expression of shRNA
WO2010045659A1 (en) 2008-10-17 2010-04-22 American Gene Technologies International Inc. Safe lentiviral vectors for targeted delivery of multiple therapeutic molecules
EP2425001A4 (en) * 2009-04-30 2012-11-14 Univ California ANTI-HIV COMBINATION VECTORS, TARGETING VECTORS AND METHOD OF USE
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WO2011011584A1 (en) 2009-07-24 2011-01-27 Immune Design Corp Lentiviral vectors pseudotyped with a sindbis virus envelope glycoprotein
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US8323662B1 (en) 2012-03-30 2012-12-04 Immune Design Corp. Methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein
US9713635B2 (en) 2012-03-30 2017-07-25 Immune Design Corp. Materials and methods for producing improved lentiviral vector particles
CN104119285B (zh) * 2013-04-28 2016-06-29 中国科学院广州生物医药与健康研究院 用作雌激素相关受体调节剂的化合物及其应用
EP3027755B1 (en) 2013-08-02 2019-10-09 The Regents of The University of California Engineering antiviral t cell immunity through stem cells and chimeric antigen receptors
CN108026543A (zh) * 2015-05-18 2018-05-11 卡琳缪恩股份有限公司 用于hiv的治疗的基因疗法及其用途
EP3319631A4 (en) * 2015-07-08 2019-01-09 American Gene Technologies International Inc. HIV PREMUNICATION AND IMMUNOTHERAPY
US10137144B2 (en) 2016-01-15 2018-11-27 American Gene Technologies International Inc. Methods and compositions for the activation of gamma-delta T-cells
CA3011529A1 (en) 2016-01-15 2017-07-20 American Gene Technologies International Inc. Methods and compositions for the activation of gamma-delta t-cells
US10888613B2 (en) * 2016-02-08 2021-01-12 American Gene Technologies International Inc. Method of producing cells resistant to HIV infection
JP6975465B2 (ja) * 2016-02-19 2021-12-08 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアThe Regents Of The University Of California 遺伝子改変細胞をポジティブに選択して、排除するための短ヘアピンｒｎａ（ｓｈｒｎａ７３４）およびその使用
ES2911448T3 (es) 2016-03-09 2022-05-19 American Gene Tech Int Inc Vectores combinados y métodos para el tratamiento del cáncer
EP3468617A4 (en) 2016-06-08 2020-01-22 American Gene Technologies International Inc. INTEGRATED VIRAL ADMINISTRATION SYSTEM AND RELATED METHODS
IL300730A (en) 2016-07-08 2023-04-01 American Gene Tech Int Inc Pre-HIV vaccine and immunotherapy
JP7176756B2 (ja) 2016-07-21 2022-11-22 アメリカン ジーン テクノロジーズ インターナショナル インコーポレイテッド パーキンソン病を処置するためのウイルスベクター
US11820999B2 (en) 2017-04-03 2023-11-21 American Gene Technologies International Inc. Compositions and methods for treating phenylketonuria
AU2018367546B2 (en) * 2017-11-15 2024-07-18 Weird Science Llc Methods and compositions for non-myeloablative bone marrow reconstitution
WO2020097049A1 (en) 2018-11-05 2020-05-14 American Gene Technologies International Inc. Vector system for expressing regulatory rna
US20250057884A1 (en) * 2021-12-31 2025-02-20 Beijing Solobio Genetechnology Co. , Ltd. Chimeric Antigen Receptor-T Cells Targeting HIV-Infected Cells

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