JP2010520757A5 - - Google Patents

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Publication number
JP2010520757A5
JP2010520757A5 JP2009552911A JP2009552911A JP2010520757A5 JP 2010520757 A5 JP2010520757 A5 JP 2010520757A5 JP 2009552911 A JP2009552911 A JP 2009552911A JP 2009552911 A JP2009552911 A JP 2009552911A JP 2010520757 A5 JP2010520757 A5 JP 2010520757A5
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JP
Japan
Prior art keywords
region
cell
retroviral construct
coding region
ltr
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JP2009552911A
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English (en)
Japanese (ja)
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JP2010520757A (ja
JP5399927B2 (ja
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Priority claimed from US11/683,962 external-priority patent/US7737124B2/en
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Publication of JP2010520757A publication Critical patent/JP2010520757A/ja
Publication of JP2010520757A5 publication Critical patent/JP2010520757A5/ja
Application granted granted Critical
Publication of JP5399927B2 publication Critical patent/JP5399927B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2009552911A 2007-03-08 2008-03-07 細胞内で細胞毒性を低減して抗ウイルス性小ｒｎａ分子を発現させる方法 Expired - Fee Related JP5399927B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/683,962 US7737124B2 (en) 2001-09-13 2007-03-08 Method for expression of small antiviral RNA molecules with reduced cytotoxicity within a cell
US11/683,962 2007-03-08
PCT/US2008/056245 WO2008109837A2 (en) 2007-03-08 2008-03-07 Method for expression of small antiviral rna molecules with reduced cytotoxicity within a cell

Publications (3)

Publication Number Publication Date
JP2010520757A JP2010520757A (ja) 2010-06-17
JP2010520757A5 true JP2010520757A5 (enExample) 2011-04-21
JP5399927B2 JP5399927B2 (ja) 2014-01-29

Family

ID=39816837

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009552911A Expired - Fee Related JP5399927B2 (ja) 2007-03-08 2008-03-07 細胞内で細胞毒性を低減して抗ウイルス性小ｒｎａ分子を発現させる方法

Country Status (6)

Country Link
US (6) US7737124B2 (enExample)
EP (1) EP2115164B1 (enExample)
JP (1) JP5399927B2 (enExample)
AU (1) AU2008222663B2 (enExample)
CA (2) CA3012986A1 (enExample)
WO (1) WO2008109837A2 (enExample)

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CA2457282C (en) * 2001-09-13 2015-01-13 California Institute Of Technology Method for expression of small antiviral rna molecules within a cell
EP1425400B1 (en) 2001-09-13 2016-11-02 California Institute Of Technology Method for producing transgenic animals
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WO2008011636A2 (en) 2006-07-21 2008-01-24 California Institute Of Technology Targeted gene delivery for dendritic cell vaccination
EP2166107A1 (en) * 2008-09-12 2010-03-24 TaconicArtemis GmbH Lentiviral vectors for the expression of shRNA
WO2010045659A1 (en) 2008-10-17 2010-04-22 American Gene Technologies International Inc. Safe lentiviral vectors for targeted delivery of multiple therapeutic molecules
EP2425001A4 (en) * 2009-04-30 2012-11-14 Univ California ANTI-HIV COMBINATION VECTORS, TARGETING VECTORS AND METHOD OF USE
US20120201794A1 (en) * 2009-07-15 2012-08-09 Calimmune Inc. Dual vector for inhibition of human immunodeficiency virus
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US8323662B1 (en) 2012-03-30 2012-12-04 Immune Design Corp. Methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein
AU2013237900B2 (en) 2012-03-30 2017-07-27 Immune Design Corp. Lentiviral vector particles having improved transduction efficiency for cells expressing DC- SIGN
US9713635B2 (en) 2012-03-30 2017-07-25 Immune Design Corp. Materials and methods for producing improved lentiviral vector particles
CN104119285B (zh) * 2013-04-28 2016-06-29 中国科学院广州生物医药与健康研究院 用作雌激素相关受体调节剂的化合物及其应用
EP3027755B1 (en) 2013-08-02 2019-10-09 The Regents of The University of California Engineering antiviral t cell immunity through stem cells and chimeric antigen receptors
CA2986469A1 (en) * 2015-05-18 2016-11-24 Calimmune, Inc. Gene therapeutic for the treatment of hiv and uses thereof
US11980663B2 (en) * 2015-07-08 2024-05-14 American Gene Technologies International Inc. HIV pre-immunization and immunotherapy
US10137144B2 (en) 2016-01-15 2018-11-27 American Gene Technologies International Inc. Methods and compositions for the activation of gamma-delta T-cells
IL297238B2 (en) 2016-01-15 2024-08-01 American Gene Tech Int Inc Methods and preparations for gamma-delta T-cell activation
JP7153332B2 (ja) * 2016-02-08 2022-10-14 アメリカン ジーン テクノロジーズ インターナショナル インコーポレイテッド Ｈｉｖワクチン接種および免疫療法
WO2017143266A1 (en) * 2016-02-19 2017-08-24 The Regents Of The University Of California Short hairpin rna (shrna734) and use of same to positively select and eliminate genetically modified cells
ES2911448T3 (es) 2016-03-09 2022-05-19 American Gene Tech Int Inc Vectores combinados y métodos para el tratamiento del cáncer
WO2017213697A1 (en) 2016-06-08 2017-12-14 American Gene Technologies International Inc. Non-integrating viral delivery system and methods related thereto
CA3028982A1 (en) 2016-07-08 2018-01-11 American Gene Technologies International Inc. Hiv pre-immunization and immunotherapy
WO2018017882A1 (en) 2016-07-21 2018-01-25 American Gene Technologies International Inc. Viral vectors for treating parkinson's disease
US11820999B2 (en) 2017-04-03 2023-11-21 American Gene Technologies International Inc. Compositions and methods for treating phenylketonuria
US12559769B2 (en) 2017-06-16 2026-02-24 American Gene Technologies International Inc. Methods and compositions for the activation of tumor cytotoxicity via human gamma-delta t-cells
JP7568507B2 (ja) * 2017-11-15 2024-10-16 ウィヤード・サイエンス・エルエルシー 非骨髄破壊的な骨髄再構成のための方法および組成物
EP3876952A4 (en) 2018-11-05 2022-08-24 American Gene Technologies International Inc. VECTOR SYSTEM FOR EXPRESSING REGULATORY RNA
JP2025501273A (ja) * 2021-12-31 2025-01-17 北京三▲諾▼佳邑生物技▲術▼有限▲責▼任公司 Ｈｉｖ感染細胞を標的とするキメラ抗原受容体ｔ細胞

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