JP2010518154A - 副作用を減少させる、tgf−ベータ刺激因子及び追加の剤 - Google Patents

副作用を減少させる、tgf−ベータ刺激因子及び追加の剤 Download PDF

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JP2010518154A
JP2010518154A JP2009549466A JP2009549466A JP2010518154A JP 2010518154 A JP2010518154 A JP 2010518154A JP 2009549466 A JP2009549466 A JP 2009549466A JP 2009549466 A JP2009549466 A JP 2009549466A JP 2010518154 A JP2010518154 A JP 2010518154A
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alkyl
pharmaceutical composition
tamoxifen
tgf
composition according
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JP2010518154A5 (enExample
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ジョン グレーンジャー,デイビッド
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ティーシーピー イノベーションズ リミティド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P3/06Antihyperlipidemics
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    • A61P35/00Antineoplastic agents
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    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
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    • A61P37/02Immunomodulators
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    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
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  • Obesity (AREA)
  • Toxicology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2009549466A 2007-02-14 2008-02-07 副作用を減少させる、tgf−ベータ刺激因子及び追加の剤 Pending JP2010518154A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0702871.5A GB0702871D0 (en) 2007-02-14 2007-02-14 Improved compositions and combinations 1
PCT/GB2008/000451 WO2008099144A2 (en) 2007-02-14 2008-02-07 Tgf-beta stimulant and further agent to reduce side effects

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JP2010518154A true JP2010518154A (ja) 2010-05-27
JP2010518154A5 JP2010518154A5 (enExample) 2011-03-31

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US (1) US20100099642A1 (enExample)
EP (1) EP2121020A2 (enExample)
JP (1) JP2010518154A (enExample)
CN (1) CN101668543A (enExample)
CA (1) CA2678127A1 (enExample)
GB (1) GB0702871D0 (enExample)
RU (1) RU2009134039A (enExample)
WO (1) WO2008099144A2 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2939314A1 (fr) * 2008-12-04 2010-06-11 Univ Victor Segalen Bordeaux 2 Nouvelles compositions et methodes pour la potentialisation des signaux d'apoptose dans les cellules tumorales
GB2475907A (en) * 2009-12-04 2011-06-08 Tcp Innovations Ltd Composition comprising a mixture of clopidogrel and droloxifene
US20110136858A1 (en) * 2009-12-04 2011-06-09 Grainger David J Preferred Combination Therapy
WO2015103355A1 (en) 2014-01-01 2015-07-09 Medivation Technologies, Inc. Compounds and methods of use
CN104211778A (zh) * 2014-09-28 2014-12-17 苏州普罗达生物科技有限公司 一种转化生长因子β1激动剂多肽及其制备方法、应用
CN104311631A (zh) * 2014-09-28 2015-01-28 苏州普罗达生物科技有限公司 转化生长因子β1激动剂多肽及其制备方法、应用
WO2020097317A1 (en) * 2018-11-07 2020-05-14 Health Research, Inc. Exploiting estrogen receptor beta and tp53 interaction as a new therapeutic strategy for cancer
CN116152157A (zh) * 2022-11-28 2023-05-23 苏州大学 基于肿瘤组织灌注影像学特征的生物标志物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6117911A (en) * 1997-04-11 2000-09-12 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6251920B1 (en) * 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6117911A (en) * 1997-04-11 2000-09-12 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JPN5010003755; GURJAL A: BLOOD V96 N11 PART 2, 20001116, P83B, AMERICAN SOCIETY OF HEMATOLOGY *
JPN6012060532; Circulation Vol.103, 2001, p.1497-1502 *
JPN6012060535; Cancer Vol.68,No.6, 1991, p.1238-1241 *
JPN6012060536; International Journal of Cardiology Vol.123, 20070208, p.66-68 *

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Publication number Publication date
WO2008099144A3 (en) 2008-12-04
EP2121020A2 (en) 2009-11-25
CN101668543A (zh) 2010-03-10
CA2678127A1 (en) 2008-08-21
WO2008099144A2 (en) 2008-08-21
US20100099642A1 (en) 2010-04-22
GB0702871D0 (en) 2007-03-28
RU2009134039A (ru) 2011-03-20

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