JP2010515704A - カンナビノイド−ｃｂ１拮抗作用とセロトニン再摂取阻害の組み合わせを示す化合物 - Google Patents
カンナビノイド−ｃｂ１拮抗作用とセロトニン再摂取阻害の組み合わせを示す化合物 Download PDFInfo
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- 235000012222 talc Nutrition 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
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- 125000002889 tridecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
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- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87953307P | 2007-01-10 | 2007-01-10 | |
| EP07100323 | 2007-01-10 | ||
| PCT/EP2008/050181 WO2008084057A1 (en) | 2007-01-10 | 2008-01-09 | Compounds with a combination of cannabinoid-cb1 antagonism and serotonin reuptake inhibition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2010515704A true JP2010515704A (ja) | 2010-05-13 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009545172A Withdrawn JP2010515704A (ja) | 2007-01-10 | 2008-01-09 | カンナビノイド−ｃｂ１拮抗作用とセロトニン再摂取阻害の組み合わせを示す化合物 |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP2111394A1 (ko) |
| JP (1) | JP2010515704A (ko) |
| KR (1) | KR20090103932A (ko) |
| AU (1) | AU2008204456A1 (ko) |
| CA (1) | CA2671554A1 (ko) |
| EA (1) | EA200970672A1 (ko) |
| IL (1) | IL198999A0 (ko) |
| WO (1) | WO2008084057A1 (ko) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US7655685B2 (en) * | 2007-11-02 | 2010-02-02 | Jenrin Discovery, Inc. | Cannabinoid receptor antagonists/inverse agonists useful for treating metabolic disorders, including obesity and diabetes |
| CA2818198A1 (en) * | 2010-11-18 | 2012-05-24 | Jenrin Discovery | Cannabinoid receptor antagonists/inverse agonists useful for treating metabolic disorders, including obesity and diabetes |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003007887A2 (en) * | 2001-07-20 | 2003-01-30 | Merck & Co., Inc. | Substituted imidazoles as cannabinoid receptor modulators |
| WO2003063781A2 (en) * | 2002-01-29 | 2003-08-07 | Merck & Co., Inc. | Substituted imidazoles as cannabinoid receptor modulators |
| RU2304580C2 (ru) * | 2002-07-29 | 2007-08-20 | Ф.Хоффманн-Ля Рош Аг | Новые бензодиоксолы |
| CN101072563A (zh) * | 2004-12-07 | 2007-11-14 | 索尔瓦药物有限公司 | 同时对多巴胺－d2受体和5－羟色胺重摄取部位具有亲合力的苯并二噁烷哌嗪衍生物 |
| RU2007125636A (ru) * | 2004-12-07 | 2009-01-20 | Солвей Фармасьютикалс Б.В. (Nl) | Фенилпиперазины с комбинацией свойств сродства к d2 допаминовым рецепторам и центрам обратного захвата серотонина |
| JP2008523030A (ja) * | 2004-12-08 | 2008-07-03 | ソルベイ・フアーマシユーチカルズ・ベー・ブイ | 部分的ドーパミン−ｄ２受容体作動性とセロトニン再摂取阻害の組み合わせを示すフェニルピペラジン誘導体 |
-
2008
- 2008-01-09 CA CA002671554A patent/CA2671554A1/en not_active Abandoned
- 2008-01-09 WO PCT/EP2008/050181 patent/WO2008084057A1/en active Application Filing
- 2008-01-09 JP JP2009545172A patent/JP2010515704A/ja not_active Withdrawn
- 2008-01-09 EA EA200970672A patent/EA200970672A1/ru unknown
- 2008-01-09 EP EP08701345A patent/EP2111394A1/en not_active Withdrawn
- 2008-01-09 KR KR1020097016686A patent/KR20090103932A/ko not_active Application Discontinuation
- 2008-01-09 AU AU2008204456A patent/AU2008204456A1/en not_active Abandoned
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2009
- 2009-05-27 IL IL198999A patent/IL198999A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL198999A0 (en) | 2010-02-17 |
| WO2008084057A1 (en) | 2008-07-17 |
| CA2671554A1 (en) | 2008-07-17 |
| EP2111394A1 (en) | 2009-10-28 |
| EA200970672A1 (ru) | 2010-02-26 |
| AU2008204456A1 (en) | 2008-07-17 |
| KR20090103932A (ko) | 2009-10-01 |
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