JP2010514683A - 化合物及びその使用 - Google Patents

化合物及びその使用 Download PDF

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Publication number
JP2010514683A
JP2010514683A JP2009543166A JP2009543166A JP2010514683A JP 2010514683 A JP2010514683 A JP 2010514683A JP 2009543166 A JP2009543166 A JP 2009543166A JP 2009543166 A JP2009543166 A JP 2009543166A JP 2010514683 A JP2010514683 A JP 2010514683A
Authority
JP
Japan
Prior art keywords
alkyl
aryl
arylalkyl
heterocycloalkyl
nhc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2009543166A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010514683A5 (enExample
Inventor
ピーター・バーンスタイン
ジェイムズ・ビー・キャンベル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of JP2010514683A publication Critical patent/JP2010514683A/ja
Publication of JP2010514683A5 publication Critical patent/JP2010514683A5/ja
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
JP2009543166A 2006-12-20 2007-12-19 化合物及びその使用 Pending JP2010514683A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87097906P 2006-12-20 2006-12-20
PCT/US2007/088053 WO2008079847A1 (en) 2006-12-20 2007-12-19 Compounds and uses thereof

Publications (2)

Publication Number Publication Date
JP2010514683A true JP2010514683A (ja) 2010-05-06
JP2010514683A5 JP2010514683A5 (enExample) 2010-12-16

Family

ID=39562912

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009543166A Pending JP2010514683A (ja) 2006-12-20 2007-12-19 化合物及びその使用

Country Status (5)

Country Link
US (1) US20100016284A1 (enExample)
EP (1) EP2099459A4 (enExample)
JP (1) JP2010514683A (enExample)
CN (1) CN101622002A (enExample)
WO (1) WO2008079847A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2307389T3 (pl) 2008-06-20 2013-05-31 Astrazeneca Ab Pochodne dibenzotiazepiny i ich zastosowanie
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
USD1032722S1 (en) 2022-04-19 2024-06-25 Ags Llc Gaming machine
USD1032723S1 (en) 2022-04-19 2024-06-25 Ags Llc Gaming machine

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003000670A1 (en) * 2001-06-26 2003-01-03 Neuromolecular, Inc. A11-piperazinyldibenzo (b, f) (1, 4) oxazepines and thiazepines as atypical antipsychotic agents having low affinity for the d2 receptor
WO2005063254A2 (en) * 2003-12-22 2005-07-14 Acadia Pharmaceuticals Inc. Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK148392D0 (da) * 1992-12-09 1992-12-09 Lundbeck & Co As H Heterocykliske forbindelser
US5538965A (en) * 1993-12-23 1996-07-23 Allelix Biopharmaceuticals Inc. Dopamine receptor ligands
US7208497B2 (en) * 2001-07-02 2007-04-24 Novo Nordisk A/S Substituted piperazines and diazepanes
US20060217366A1 (en) * 2003-07-02 2006-09-28 Astrazeneca Ab Method of treating schizophrenia and other disorders

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003000670A1 (en) * 2001-06-26 2003-01-03 Neuromolecular, Inc. A11-piperazinyldibenzo (b, f) (1, 4) oxazepines and thiazepines as atypical antipsychotic agents having low affinity for the d2 receptor
WO2005063254A2 (en) * 2003-12-22 2005-07-14 Acadia Pharmaceuticals Inc. Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders

Also Published As

Publication number Publication date
EP2099459A4 (en) 2011-04-27
EP2099459A1 (en) 2009-09-16
WO2008079847A1 (en) 2008-07-03
US20100016284A1 (en) 2010-01-21
CN101622002A (zh) 2010-01-06

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DameWood Jr., Wilmington, DE (US); Ashokkumar 1 lilékkgppa sa ‘jnvli W11E1I {% t.? n’. DE GB 1164360 9/1969

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