JP2010513311A - コレステロール流出の強力かつ選択的なメディエータ - Google Patents
コレステロール流出の強力かつ選択的なメディエータ Download PDFInfo
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- JP2010513311A JP2010513311A JP2009541599A JP2009541599A JP2010513311A JP 2010513311 A JP2010513311 A JP 2010513311A JP 2009541599 A JP2009541599 A JP 2009541599A JP 2009541599 A JP2009541599 A JP 2009541599A JP 2010513311 A JP2010513311 A JP 2010513311A
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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Landscapes
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| PCT/US2007/087477 WO2008115303A2 (en) | 2006-12-13 | 2007-12-13 | Potent and selective mediators of cholesterol efflux |
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| JP2016516054A (ja) * | 2013-03-15 | 2016-06-02 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | コレステロール流出を刺激する、減少した毒性を有するペプチド |
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| RU2011101536A (ru) | 2008-06-18 | 2012-07-27 | Дзе Риджентс Оф Дзе Юниверсити Оф Калифорниа (Us) | Усовершенствованные пептидные медиаторы оттока холестерина |
| EP2517013A4 (en) * | 2009-12-23 | 2013-07-17 | Artery Therapeutics Inc | DIAGNOSIS AND TREATMENT OF DISEASES ASSOCIATED WITH DEFICIENT REVERSE CHOLESTER INTRANSPORT |
| WO2011139819A2 (en) * | 2010-04-28 | 2011-11-10 | The Regents Of The University Of California | Creation of oxidation-resistant hdl mimetic peptides |
| US11091529B2 (en) * | 2014-09-17 | 2021-08-17 | The Regents Of The University Of California | Peptides having reduced toxicity that stimulate cholesterol efflux |
| CN112442114A (zh) | 2019-08-29 | 2021-03-05 | 渥太华Hdl药物研发公司 | 一种多肽及其应用 |
| CN112511569B (zh) * | 2021-02-07 | 2021-05-11 | 杭州筋斗腾云科技有限公司 | 网络资源访问请求的处理方法、系统及计算机设备 |
Citations (4)
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| JP2003530835A (ja) * | 2000-04-06 | 2003-10-21 | ケイオウエス ファーマシューティカルズ インコーポレイテッド | 高トリグリセリド血症を誘発することなくコレステロールレベルを低下するための化合物と方法 |
| JP2004506693A (ja) * | 2000-08-24 | 2004-03-04 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | アテローム性動脈硬化症を改善する経口投与ペプチド |
| WO2005058938A2 (en) * | 2003-12-15 | 2005-06-30 | The Regents Of The University Of California | Helical synthetic peptides that stimulate cellular cholesterol efflux |
| WO2006020040A2 (en) * | 2004-07-16 | 2006-02-23 | Trustees Of Tufts College | Apolipoprotein a1 mimetics and uses thereof |
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| DE60035163T2 (de) | 1999-03-15 | 2008-02-21 | University Of British Columbia, Vancouver | Abc1 polypeptide und verfahren und reagenzien zur modulation des cholesterolgehalts |
| US7199102B2 (en) | 2000-08-24 | 2007-04-03 | The Regents Of The University Of California | Orally administered peptides synergize statin activity |
| US8541236B2 (en) | 2006-12-08 | 2013-09-24 | University Of Washington | Mutant apolipoprotein A-1 polypeptide with increased resistance to oxidation and reactive carbonyls |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003530835A (ja) * | 2000-04-06 | 2003-10-21 | ケイオウエス ファーマシューティカルズ インコーポレイテッド | 高トリグリセリド血症を誘発することなくコレステロールレベルを低下するための化合物と方法 |
| JP2004506693A (ja) * | 2000-08-24 | 2004-03-04 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | アテローム性動脈硬化症を改善する経口投与ペプチド |
| WO2005058938A2 (en) * | 2003-12-15 | 2005-06-30 | The Regents Of The University Of California | Helical synthetic peptides that stimulate cellular cholesterol efflux |
| WO2006020040A2 (en) * | 2004-07-16 | 2006-02-23 | Trustees Of Tufts College | Apolipoprotein a1 mimetics and uses thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016516054A (ja) * | 2013-03-15 | 2016-06-02 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | コレステロール流出を刺激する、減少した毒性を有するペプチド |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2007349237B2 (en) | 2014-01-23 |
| EP2121746A2 (en) | 2009-11-25 |
| ES2377329T3 (es) | 2012-03-26 |
| CA2672131C (en) | 2016-06-07 |
| ATE533783T1 (de) | 2011-12-15 |
| HK1138292A1 (en) | 2010-08-20 |
| WO2008115303A2 (en) | 2008-09-25 |
| WO2008115303A3 (en) | 2008-12-24 |
| CA2672131A1 (en) | 2008-09-25 |
| US8987192B2 (en) | 2015-03-24 |
| US20120329703A1 (en) | 2012-12-27 |
| EP2121746B1 (en) | 2011-11-16 |
| DK2121746T3 (da) | 2012-03-05 |
| CN101675072A (zh) | 2010-03-17 |
| AU2007349237A1 (en) | 2008-09-25 |
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