ATE533783T1 - Potente und selektive mittlersubstanzen von cholesterolefflux - Google Patents
Potente und selektive mittlersubstanzen von cholesteroleffluxInfo
- Publication number
- ATE533783T1 ATE533783T1 AT07874411T AT07874411T ATE533783T1 AT E533783 T1 ATE533783 T1 AT E533783T1 AT 07874411 T AT07874411 T AT 07874411T AT 07874411 T AT07874411 T AT 07874411T AT E533783 T1 ATE533783 T1 AT E533783T1
- Authority
- AT
- Austria
- Prior art keywords
- cholesterolefflux
- potent
- polypeptides
- apo
- parallels
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87490906P | 2006-12-13 | 2006-12-13 | |
PCT/US2007/087477 WO2008115303A2 (en) | 2006-12-13 | 2007-12-13 | Potent and selective mediators of cholesterol efflux |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE533783T1 true ATE533783T1 (de) | 2011-12-15 |
Family
ID=39766652
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT07874411T ATE533783T1 (de) | 2006-12-13 | 2007-12-13 | Potente und selektive mittlersubstanzen von cholesterolefflux |
Country Status (11)
Country | Link |
---|---|
US (1) | US8987192B2 (de) |
EP (1) | EP2121746B1 (de) |
JP (1) | JP2010513311A (de) |
CN (1) | CN101675072A (de) |
AT (1) | ATE533783T1 (de) |
AU (1) | AU2007349237B2 (de) |
CA (1) | CA2672131C (de) |
DK (1) | DK2121746T3 (de) |
ES (1) | ES2377329T3 (de) |
HK (1) | HK1138292A1 (de) |
WO (1) | WO2008115303A2 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2009260024A1 (en) | 2008-06-18 | 2009-12-23 | The Regents Of The University Of California | Improved peptide mediators of cholesterol efflux |
EP2517013A4 (de) * | 2009-12-23 | 2013-07-17 | Artery Therapeutics Inc | Diagnose und behandlung von erkrankungen im zusammenhang mit defizientem reversem cholesterintransport |
WO2011139819A2 (en) * | 2010-04-28 | 2011-11-10 | The Regents Of The University Of California | Creation of oxidation-resistant hdl mimetic peptides |
US10017551B2 (en) | 2013-03-15 | 2018-07-10 | The Regents Of The University Of California | Peptides having reduced toxicity that stimulate cholesterol efflux |
WO2016044177A1 (en) * | 2014-09-17 | 2016-03-24 | The Regents Of The University Of California | Peptides having reduced toxicity that stimulate cholesterol efflux |
CN112442114A (zh) * | 2019-08-29 | 2021-03-05 | 渥太华Hdl药物研发公司 | 一种多肽及其应用 |
CN112511569B (zh) * | 2021-02-07 | 2021-05-11 | 杭州筋斗腾云科技有限公司 | 网络资源访问请求的处理方法、系统及计算机设备 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2367955C (en) | 1999-03-15 | 2009-05-19 | University Of British Columbia | Abc1 polypeptide and methods and reagents for modulating cholesterol levels |
CA2405870A1 (en) * | 2000-04-06 | 2001-10-18 | Kos Pharmaceuticals, Inc. | Compounds and methods for lowering cholesterol levels without inducing hypertriglyceridemia |
US7199102B2 (en) | 2000-08-24 | 2007-04-03 | The Regents Of The University Of California | Orally administered peptides synergize statin activity |
US6664230B1 (en) * | 2000-08-24 | 2003-12-16 | The Regents Of The University Of California | Orally administered peptides to ameliorate atherosclerosis |
WO2005058938A2 (en) | 2003-12-15 | 2005-06-30 | The Regents Of The University Of California | Helical synthetic peptides that stimulate cellular cholesterol efflux |
JP5048486B2 (ja) * | 2004-07-16 | 2012-10-17 | トラスティーズ オブ タフツ カレッジ | アポリポタンパク質a1の模倣物とその使用 |
US8541236B2 (en) | 2006-12-08 | 2013-09-24 | University Of Washington | Mutant apolipoprotein A-1 polypeptide with increased resistance to oxidation and reactive carbonyls |
-
2007
- 2007-12-13 CA CA2672131A patent/CA2672131C/en not_active Expired - Fee Related
- 2007-12-13 CN CN200780046286A patent/CN101675072A/zh active Pending
- 2007-12-13 ES ES07874411T patent/ES2377329T3/es active Active
- 2007-12-13 EP EP07874411A patent/EP2121746B1/de not_active Not-in-force
- 2007-12-13 JP JP2009541599A patent/JP2010513311A/ja active Pending
- 2007-12-13 DK DK07874411.7T patent/DK2121746T3/da active
- 2007-12-13 US US12/519,116 patent/US8987192B2/en active Active
- 2007-12-13 AT AT07874411T patent/ATE533783T1/de active
- 2007-12-13 WO PCT/US2007/087477 patent/WO2008115303A2/en active Application Filing
- 2007-12-13 AU AU2007349237A patent/AU2007349237B2/en not_active Ceased
-
2010
- 2010-05-24 HK HK10105040.7A patent/HK1138292A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP2121746B1 (de) | 2011-11-16 |
CN101675072A (zh) | 2010-03-17 |
ES2377329T3 (es) | 2012-03-26 |
CA2672131C (en) | 2016-06-07 |
US8987192B2 (en) | 2015-03-24 |
US20120329703A1 (en) | 2012-12-27 |
CA2672131A1 (en) | 2008-09-25 |
JP2010513311A (ja) | 2010-04-30 |
HK1138292A1 (en) | 2010-08-20 |
AU2007349237B2 (en) | 2014-01-23 |
DK2121746T3 (da) | 2012-03-05 |
WO2008115303A2 (en) | 2008-09-25 |
WO2008115303A3 (en) | 2008-12-24 |
EP2121746A2 (de) | 2009-11-25 |
AU2007349237A1 (en) | 2008-09-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE533783T1 (de) | Potente und selektive mittlersubstanzen von cholesterolefflux | |
WO2009155366A3 (en) | Improved peptide mediators of cholesterol efflux | |
BRPI0506771A (pt) | anticorpo, e, composição farmacêutica | |
DE60219419D1 (de) | Flt4 (vegfr-3) als ein ziel für krebs darstellung und anti-krebs-behandlung | |
WO2006053315A3 (en) | Methods and compositions for treating cellular proliferative diseases | |
WO2005095457A3 (en) | Immunoglobulins | |
EP1993560A4 (de) | Cannabinoid-rezeptor-antagonisten / inverse agonisten zur behandlung von übergewicht | |
WO2007076055A3 (en) | Compositions and methods comprising proteinase activated receptor antagonists | |
WO2006124748A3 (en) | Multicyclic compounds and methods of their use | |
WO2007135571A3 (en) | Blood group antigens of different types for diagnostic and therapeutic applications | |
WO2008034016A3 (en) | Assays for detecting native-state proteins and identifying compounds that modulate the stability of native-state proteins | |
WO2006096487A3 (en) | Methods and compositions for modulating tweak and fn14 activity | |
NO20082699L (no) | Immunoglobuliner | |
WO2006076736A3 (en) | Methods for modulating angiogenesis, lymphangiogenesis, and apoptosis with apelin compositions | |
WO2007059341A3 (en) | Pyrazolothiazole protein kinase modulators | |
WO2011003100A3 (en) | Compositions and methods for diagnosing and/or treating influenza infection | |
WO2007111982A3 (en) | Methods for treating cognitive and other disorders | |
WO2007067737A3 (en) | Methods and compositions for inhibiting hiv infection | |
WO2007034490A3 (en) | Diastereomeric peptides for modulating t cell immunity | |
WO2004111089A3 (en) | Platelet glycoprotein ib alpha variant fusion polypeptides and methods of use thereof | |
WO2006129867A3 (en) | ENHANCED EXPRESSION OF LACTOFERRIN mRNA BY LACRITIN | |
WO2003038130A8 (en) | Therapeutics and diagnostics for disorders of erythropoiesis | |
WO2005094159A3 (en) | Methods of identifying neoplasm-specific antibodies and uses thereof | |
WO2011139819A3 (en) | Creation of oxidation-resistant hdl mimetic peptides | |
WO2021024133A3 (en) | Biopharmacuetical compositions and related methods |