JP2010508337A - Ｉｋｋ−ベータセリン−スレオニンプロテインキナーゼの阻害剤 - Google Patents
Ｉｋｋ−ベータセリン−スレオニンプロテインキナーゼの阻害剤 Download PDFInfo
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- JP2010508337A JP2010508337A JP2009535117A JP2009535117A JP2010508337A JP 2010508337 A JP2010508337 A JP 2010508337A JP 2009535117 A JP2009535117 A JP 2009535117A JP 2009535117 A JP2009535117 A JP 2009535117A JP 2010508337 A JP2010508337 A JP 2010508337A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0621720A GB0621720D0 (en) | 2006-11-01 | 2006-11-01 | Inhibitors of ikk- serine-threonine protein kinase |
| GB0715469A GB0715469D0 (en) | 2007-08-09 | 2007-08-09 | Inhibitors of IKK serine-threonine protein kinase |
| PCT/GB2007/004117 WO2008053185A1 (en) | 2006-11-01 | 2007-10-29 | INHIBITORS OF IKK-β SERINE-THREONINE PROTEIN KINASE |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010508337A true JP2010508337A (ja) | 2010-03-18 |
| JP2010508337A5 JP2010508337A5 (enExample) | 2010-12-16 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009535117A Withdrawn JP2010508337A (ja) | 2006-11-01 | 2007-10-29 | Ｉｋｋ−ベータセリン−スレオニンプロテインキナーゼの阻害剤 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8106091B2 (enExample) |
| EP (1) | EP2086956B1 (enExample) |
| JP (1) | JP2010508337A (enExample) |
| AT (1) | ATE524454T1 (enExample) |
| WO (1) | WO2008053185A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0619753D0 (en) | 2006-10-06 | 2006-11-15 | Chroma Therapeutics Ltd | Enzyme inhibitors |
| GB0803747D0 (en) | 2008-02-29 | 2008-04-09 | Martin | Enzyme and receptor modulation |
| MX2010011501A (es) * | 2008-04-23 | 2010-11-30 | Chroma Therapeutics Ltd | Inhibidores de proteina cinasa de serina-treonina ikk-beta. |
| BRPI0911480A2 (pt) * | 2008-04-26 | 2018-04-03 | Chroma Therapeutics Ltd | inibidores de proteínas serina-treonina quinase ikk-beta |
| WO2010062829A1 (en) * | 2008-11-28 | 2010-06-03 | Lexicon Pharmaceuticals, Inc. | Tryptophan hydroxylase inhibitors for treating osteoporosis |
| GB0903480D0 (en) | 2009-02-27 | 2009-04-08 | Chroma Therapeutics Ltd | Enzyme Inhibitors |
| GB201211310D0 (en) | 2012-06-26 | 2012-08-08 | Chroma Therapeutics Ltd | CSF-1R kinase inhibitors |
| AR091858A1 (es) * | 2012-07-25 | 2015-03-04 | Sova Pharmaceuticals Inc | INHIBIDORES DE CISTATIONIN-g-LIASA (CSE) |
| HRP20171320T1 (hr) | 2012-10-17 | 2017-10-20 | Macrophage Pharma Limited | Terc-butil n-[2-{4-[6-amino-5-(2,4-difluorobenzoil)-2-oksopiridin-1(2h)-il]-3,5-difluorofenil}etil]-l-alaninat ili njegova sol, hidrat ili solvat |
| CN107098924A (zh) * | 2017-05-19 | 2017-08-29 | 暨南大学 | 一种芳基硼酸酯修饰的氨基酸衍生物及其制备方法与应用 |
| GB201713975D0 (en) | 2017-08-31 | 2017-10-18 | Macrophage Pharma Ltd | Medical use |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0102616D0 (sv) | 2001-07-25 | 2001-07-25 | Astrazeneca Ab | Novel compounds |
| SE0300092D0 (sv) | 2003-01-15 | 2003-01-15 | Astrazeneca Ab | Novel compounds |
-
2007
- 2007-10-29 EP EP07824361A patent/EP2086956B1/en not_active Not-in-force
- 2007-10-29 AT AT07824361T patent/ATE524454T1/de not_active IP Right Cessation
- 2007-10-29 JP JP2009535117A patent/JP2010508337A/ja not_active Withdrawn
- 2007-10-29 WO PCT/GB2007/004117 patent/WO2008053185A1/en not_active Ceased
- 2007-10-29 US US12/447,271 patent/US8106091B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008053185A1 (en) | 2008-05-08 |
| ATE524454T1 (de) | 2011-09-15 |
| EP2086956B1 (en) | 2011-09-14 |
| US8106091B2 (en) | 2012-01-31 |
| EP2086956A1 (en) | 2009-08-12 |
| US20100069473A1 (en) | 2010-03-18 |
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