JP2010505386A5 - - Google Patents
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- Publication number
- JP2010505386A5 JP2010505386A5 JP2009511025A JP2009511025A JP2010505386A5 JP 2010505386 A5 JP2010505386 A5 JP 2010505386A5 JP 2009511025 A JP2009511025 A JP 2009511025A JP 2009511025 A JP2009511025 A JP 2009511025A JP 2010505386 A5 JP2010505386 A5 JP 2010505386A5
- Authority
- JP
- Japan
- Prior art keywords
- cycle arrest
- cell cycle
- induction
- cell
- cdki protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74721306P | 2006-05-15 | 2006-05-15 | |
| PCT/US2007/011623 WO2007133773A2 (en) | 2006-05-15 | 2007-05-15 | Identification of cdki pathway inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010505386A JP2010505386A (ja) | 2010-02-25 |
| JP2010505386A5 true JP2010505386A5 (cg-RX-API-DMAC10.html) | 2010-07-08 |
Family
ID=38694544
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009511025A Pending JP2010505386A (ja) | 2006-05-15 | 2007-05-15 | Ｃｄｋｉ経路阻害剤の同定 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20080033000A1 (cg-RX-API-DMAC10.html) |
| EP (1) | EP2021019A4 (cg-RX-API-DMAC10.html) |
| JP (1) | JP2010505386A (cg-RX-API-DMAC10.html) |
| AU (1) | AU2007249762A1 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2652341A1 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2007133773A2 (cg-RX-API-DMAC10.html) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005048953A2 (en) | 2003-11-13 | 2005-06-02 | Ambit Biosciences Corporation | Amide derivatives as kinase modulators |
| US7829574B2 (en) | 2008-05-09 | 2010-11-09 | Hutchison Medipharma Enterprises Limited | Substituted quinazoline compounds and their use in treating angiogenesis-related diseases |
| NZ590355A (en) * | 2008-07-10 | 2013-01-25 | Yakult Honsha Kk | Stat3 inhibitor containing quinolinecarboxamide derivative as active ingredient |
| US20100190807A1 (en) * | 2008-08-26 | 2010-07-29 | Senex Biotechnology, Inc. | CDKI Pathway inhibitors and uses thereof to regulate expression to TAU protein |
| AR079814A1 (es) | 2009-12-31 | 2012-02-22 | Otsuka Pharma Co Ltd | Compuestos heterociclicos, composiciones farmaceuticas que los contienen y sus usos |
| BR112013033417A2 (pt) | 2011-06-29 | 2016-08-16 | Otsuka Pharma Co Ltd | compostos terapêuticos e métodos relacionados de uso |
| CN104363913B (zh) * | 2012-02-02 | 2018-08-21 | 申内克斯生物科技公司 | Cdk8/cdk19选择性抑制剂及其在癌症的抗转移和化学预防方法中的用途 |
| CA3081443A1 (en) * | 2014-12-15 | 2016-06-23 | The Regents Of The University Of Michigan | Small molecule inhibitors of egfr and pi3k |
| DK3484474T3 (da) | 2016-07-13 | 2024-06-24 | Childrens Medical Ct Corp | Phenothiazinforbindelser til behandlingen af ribosomale lidelser og ribosomopatier |
| CA2994329A1 (en) | 2017-06-08 | 2018-12-08 | The Children's Medical Center Corporation | Compounds and methods for treatment of diamond blackfan anemia |
| RU2763347C2 (ru) * | 2018-03-01 | 2021-12-28 | Закрытое Акционерное Общество "Биокад" | Новые ингибиторы cdk8/19 |
| JP2022544700A (ja) * | 2019-08-22 | 2022-10-20 | バイオヘイブン・セラピューティクス・リミテッド | 筋萎縮性側索硬化症および関連障害の治療のためにｔｄｐ－４３に結合する分子 |
| EP4746884A2 (en) * | 2023-07-21 | 2026-05-27 | Icahn School of Medicine at Mount Sinai | G9a/glp inhibitors and methods of use |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5480883A (en) * | 1991-05-10 | 1996-01-02 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase |
| GB9603095D0 (en) * | 1996-02-14 | 1996-04-10 | Zeneca Ltd | Quinazoline derivatives |
| GB9922173D0 (en) * | 1999-09-21 | 1999-11-17 | Zeneca Ltd | Chemical compounds |
| CA2463563A1 (en) * | 2001-10-12 | 2003-04-17 | Irm Llc | Kinase inhibitor scaffolds and methods for their preparation |
| WO2004065392A1 (en) * | 2003-01-24 | 2004-08-05 | Smithkline Beecham Corporation | Condensed pyridines and pyrimidines and their use as alk-5 receptor ligands |
| CA2557433C (en) * | 2004-02-19 | 2013-05-14 | Rexahn Corporation | Quinazoline derivatives and therapeutic use thereof |
| EP1748991A1 (en) * | 2004-04-28 | 2007-02-07 | Arrow Therapeutics Limited | Morpholinylanilinoquinazo- line derivatives for use as antiviral agents |
| WO2006076470A2 (en) * | 2005-01-13 | 2006-07-20 | Senex Biotechnology, Inc. | High-content screening for drugs against cancer and age-related diseases |
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2007
- 2007-05-15 US US11/803,693 patent/US20080033000A1/en not_active Abandoned
- 2007-05-15 CA CA002652341A patent/CA2652341A1/en not_active Abandoned
- 2007-05-15 WO PCT/US2007/011623 patent/WO2007133773A2/en not_active Ceased
- 2007-05-15 JP JP2009511025A patent/JP2010505386A/ja active Pending
- 2007-05-15 EP EP07794887A patent/EP2021019A4/en not_active Withdrawn
- 2007-05-15 AU AU2007249762A patent/AU2007249762A1/en not_active Abandoned