JP2010502568A5 - - Google Patents
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- Publication number
- JP2010502568A5 JP2010502568A5 JP2009511004A JP2009511004A JP2010502568A5 JP 2010502568 A5 JP2010502568 A5 JP 2010502568A5 JP 2009511004 A JP2009511004 A JP 2009511004A JP 2009511004 A JP2009511004 A JP 2009511004A JP 2010502568 A5 JP2010502568 A5 JP 2010502568A5
- Authority
- JP
- Japan
- Prior art keywords
- halogen
- hydrogen
- composition
- aryl
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 9
- 125000000217 alkyl group Chemical group 0.000 claims 8
- 229910052736 halogen Inorganic materials 0.000 claims 8
- 229910052739 hydrogen Inorganic materials 0.000 claims 8
- 239000001257 hydrogen Substances 0.000 claims 8
- 125000003118 aryl group Chemical group 0.000 claims 6
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 4
- 125000004104 aryloxy group Chemical group 0.000 claims 4
- 125000000000 cycloalkoxy group Chemical group 0.000 claims 4
- 125000000753 cycloalkyl group Chemical group 0.000 claims 4
- 125000005843 halogen group Chemical group 0.000 claims 4
- 150000002367 halogens Chemical class 0.000 claims 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 4
- 125000004043 oxo group Chemical group O=* 0.000 claims 4
- 229920006395 saturated elastomer Polymers 0.000 claims 4
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 3
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 3
- 239000004215 Carbon black (E152) Substances 0.000 claims 2
- 125000004423 acyloxy group Chemical group 0.000 claims 2
- 125000003545 alkoxy group Chemical group 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 229930195733 hydrocarbon Natural products 0.000 claims 2
- 150000002430 hydrocarbons Chemical class 0.000 claims 2
- 125000001183 hydrocarbyl group Chemical group 0.000 claims 2
- 150000002431 hydrogen Chemical class 0.000 claims 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 208000035143 Bacterial infection Diseases 0.000 claims 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims 1
- 102000057297 Pepsin A Human genes 0.000 claims 1
- 108090000284 Pepsin A Proteins 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 208000022362 bacterial infectious disease Diseases 0.000 claims 1
- 210000001198 duodenum Anatomy 0.000 claims 1
- 210000003238 esophagus Anatomy 0.000 claims 1
- 125000001153 fluoro group Chemical group F* 0.000 claims 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 1
- 229940111202 pepsin Drugs 0.000 claims 1
- 230000001737 promoting effect Effects 0.000 claims 1
- 230000028327 secretion Effects 0.000 claims 1
- 210000002784 stomach Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84238206P | 2006-09-06 | 2006-09-06 | |
| US60/842,382 | 2006-09-06 | ||
| PCT/JP2007/067693 WO2008029949A1 (en) | 2006-09-06 | 2007-09-05 | Method and composition for promoting gastrointestinal bicarbonate secretion |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010502568A JP2010502568A (ja) | 2010-01-28 |
| JP2010502568A5 true JP2010502568A5 (cg-RX-API-DMAC7.html) | 2010-10-21 |
| JP5427029B2 JP5427029B2 (ja) | 2014-02-26 |
Family
ID=38895839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009511004A Active JP5427029B2 (ja) | 2006-09-06 | 2007-09-05 | 消化管の重炭酸分泌を促進するための方法および組成物 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US7868045B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2059247A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5427029B2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008029949A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5427029B2 (ja) * | 2006-09-06 | 2014-02-26 | スキャンポ・アーゲー | 消化管の重炭酸分泌を促進するための方法および組成物 |
| US20090012165A1 (en) * | 2007-07-03 | 2009-01-08 | Sucampo Ag | Pharmaceutical combination of nsaid and prostaglandin compound |
| WO2014159679A1 (en) | 2013-03-12 | 2014-10-02 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Methods for using lubiprostone to absorb fluid from the subretinal space |
| KR20210131457A (ko) | 2013-06-05 | 2021-11-02 | 트리시다, 인크. | 경구 투여를 위한 양성자-결합 중합체 |
| ES2787218T3 (es) | 2014-12-10 | 2020-10-15 | Tricida Inc | Polímeros de unión de protones para la administración oral |
| EP3452028A4 (en) | 2016-05-06 | 2020-04-15 | Tricida Inc. | COMPOSITIONS AND METHOD FOR TREATING ACID-BASED DISORDERS |
| SG11202003451UA (en) | 2017-11-03 | 2020-05-28 | Tricida Inc | Compositions for and method of treating acid-base disorders |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8410396D0 (en) | 1984-04-24 | 1984-05-31 | Glaxo Group Ltd | Carbocyclic compounds |
| US5166174A (en) * | 1987-01-28 | 1992-11-24 | K.K. Ueno Seiyaku Oyo Kenkyujo | Prostaglandins E and anti-ulcers containing same |
| BR0212233A (pt) * | 2001-08-31 | 2004-10-05 | Sucampo Ag | Abridor de canal de cloreto |
| KR101164838B1 (ko) * | 2002-12-27 | 2012-07-11 | 수캄포 아게 | 복부 불쾌감 치료용 프로스타글랜딘의 유도체 |
| US20060281818A1 (en) | 2005-03-21 | 2006-12-14 | Sucampo Ag, North Carolina State University | Method for treating mucosal disorders |
| ES2371658T3 (es) * | 2005-04-12 | 2012-01-05 | Sucampo Ag | Uso combinado de compuesto de prostaglandina e inhibidor de la bomba de protones para el tratamiento de trastornos gastrointestinales. |
| JP5427029B2 (ja) * | 2006-09-06 | 2014-02-26 | スキャンポ・アーゲー | 消化管の重炭酸分泌を促進するための方法および組成物 |
-
2007
- 2007-09-05 JP JP2009511004A patent/JP5427029B2/ja active Active
- 2007-09-05 WO PCT/JP2007/067693 patent/WO2008029949A1/en not_active Ceased
- 2007-09-05 EP EP07807102A patent/EP2059247A1/en not_active Withdrawn
- 2007-09-05 US US11/850,271 patent/US7868045B2/en active Active
-
2010
- 2010-11-23 US US12/952,626 patent/US8530519B2/en active Active