JP2010501483A5 - - Google Patents

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Publication number
JP2010501483A5
JP2010501483A5 JP2009524574A JP2009524574A JP2010501483A5 JP 2010501483 A5 JP2010501483 A5 JP 2010501483A5 JP 2009524574 A JP2009524574 A JP 2009524574A JP 2009524574 A JP2009524574 A JP 2009524574A JP 2010501483 A5 JP2010501483 A5 JP 2010501483A5
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JP
Japan
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imaging agent
imaging
agent according
spectroscopy
item
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JP2009524574A
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English (en)
Japanese (ja)
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JP2010501483A (ja
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Priority claimed from PCT/NO2007/000287 external-priority patent/WO2008020765A2/en
Publication of JP2010501483A publication Critical patent/JP2010501483A/ja
Publication of JP2010501483A5 publication Critical patent/JP2010501483A5/ja
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JP2009524574A 2006-08-18 2007-08-17 乳酸塩及び過分極13c−ピルビン酸塩を含むイメージング剤 Withdrawn JP2010501483A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20063701 2006-08-18
PCT/NO2007/000287 WO2008020765A2 (en) 2006-08-18 2007-08-17 Imaging medium comprising lactate and hyperpolarised 13c-pyruvate

Publications (2)

Publication Number Publication Date
JP2010501483A JP2010501483A (ja) 2010-01-21
JP2010501483A5 true JP2010501483A5 (https=) 2010-08-26

Family

ID=38719770

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009524574A Withdrawn JP2010501483A (ja) 2006-08-18 2007-08-17 乳酸塩及び過分極13c−ピルビン酸塩を含むイメージング剤

Country Status (6)

Country Link
US (1) US20100178249A1 (https=)
EP (1) EP2051739A2 (https=)
JP (1) JP2010501483A (https=)
KR (1) KR20090052859A (https=)
CN (1) CN101505802A (https=)
WO (1) WO2008020765A2 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010230330B2 (en) * 2009-04-02 2015-06-25 Ge Healthcare Limited Use of a magnetic resonance imaging medium comprising hyperpolarized 13C pyruvate for the detection of inflammation or infection
US8968703B2 (en) 2009-09-10 2015-03-03 Ge Healthcare Limited 13C-MR detection using hyperpolarised 13C-fructose
JP5879333B2 (ja) 2010-05-03 2016-03-08 ジーイー・ヘルスケア・リミテッド Ldh活性を決定するための過分極乳酸塩造影剤
WO2012145733A1 (en) 2011-04-22 2012-10-26 Vanderbilt University Para-hydrogen polarizer
US10265421B2 (en) 2013-01-31 2019-04-23 Bracco Imaging S.P.A. Hyperpolarized esters as metabolic markers in MR
DK3058375T3 (en) * 2013-10-15 2019-04-08 Univ Muenchen Tech pH Biosensors based on compounds made of pyruvic acid for magnetic resonance imaging and spectroscopy and their applications
EP2863229A1 (en) 2013-10-15 2015-04-22 Technische Universität München pH-biosensors based on compounds with pH-sensitive enolic groups for magnetic resonance imaging and spectroscopy and their uses
KR101516634B1 (ko) * 2014-07-09 2015-05-06 연세대학교 산학협력단 13c-자기공명분광영상을 이용한 암 환자의 치료 예후를 예측하는 방법
WO2017136700A1 (en) 2016-02-05 2017-08-10 The Trustees Of The University Of Pennsylvania Non-nutritive sweeteners and polyols as imaging agents
US10901058B2 (en) 2016-02-05 2021-01-26 The Trustees Of The University Of Pennsylvania Chemical exchange saturation transfer (CEST) imaging of lactate (LATEST)
KR101939454B1 (ko) * 2017-03-21 2019-01-16 전남대학교산학협력단 생체 내 과분극화 c13 피루베이트 자기공명분광법을 이용하여 새로운 정량적 생체지표를 통한 비알코올성 지방간질환 진단 방법
KR102457806B1 (ko) * 2020-11-02 2022-10-28 전남대학교 산학협력단 과분극화된 13c 피루베이트 자기공명분광영상을 이용한 만성 간질환의 예후 판단을 위한 정보제공방법
WO2024254159A1 (en) * 2023-06-05 2024-12-12 The Regents Of The University Of California Compositions and method for diagnosing and treating alzheimer's disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6329208B1 (en) * 1997-07-16 2001-12-11 Board Of Regents, The University Of Texas System Methods for determining gluconeogenesis, anapleurosis and pyruvate recycling
EP1302465A1 (en) * 2001-10-11 2003-04-16 BRACCO IMAGING S.p.A. Enhanced substrate imaging by reversible binding to a paramagnetic complex
WO2006011810A2 (en) * 2004-07-30 2006-02-02 Ge Healthcare As Mr imaging method for the discrimination between healthy and tumour tissue
WO2006054903A2 (en) * 2004-11-19 2006-05-26 Ge Healthcare As Method of cardiac imaging with the use of hyperpolarized 13 c-pyruvate
US20100233096A1 (en) * 2006-03-29 2010-09-16 Lerche Mathilde H Method to produce hyperpolarised carboxylates and sulphonates
CN101506679B (zh) * 2006-08-18 2013-03-06 通用电气医疗集团股份有限公司 细胞死亡的13c-mr成像或波谱分析

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