JP2010273988A - Catheter - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a catheter capable of absorbing a change caused by a motion of a biological tissue while positioning a penetrating hole through the biological tissue certainly. <P>SOLUTION: The catheter has a long and narrow catheter body 2 including a first lumen 10 and a second lumen 11 inside, a first opening 7 for taking a fluid body into the first lumen 10 and a second opening 8 for taking the fluid body into the second lumen 11 at the proximal end, and at least one first penetrating hole 5 communicating with the first lumen 10 and the second penetrating hole 9 communicating with the second lumen 11, and the catheter also has at least one balloon 3 communicating with the second lumen 11, which is fixed to the catheter body 2 without covering the first penetrating hole 5 during expansion and composed to regulate the position of the catheter body 2 from the outside of the biological tissue 12 to the biological tissue 12 during expansion. <P>COPYRIGHT: (C)2011,JPO&INPIT

Description

  The present invention relates to a catheter used by being inserted into a living body.

  Conventionally, a catheter inserted into a human or a mammal other than a human has an elongated tubular shape having a channel therein. A portion of the tubular casing that is inserted into the body is provided with a through hole that communicates the internal channel with the outside for the purpose of discharging the medicine.

  Japanese Patent Application Laid-Open No. H10-228707 describes a balloon provided to close the distal end opening of the catheter.

  Non-Patent Document 1 describes a catheter that is placed in the urethra or bladder and used for urination, infusion and discharge of drug solution, hemostasis, and the like, and a balloon is provided at the distal end of the catheter.

JP 2002-119597 A

Incorporated administrative agency Pharmaceuticals and Medical Devices Agency, package insert information of ethical drugs, “JMS (registered trademark) Foley catheter”, medical device approval number 16300BZY00666000, revised on January 19, 2006 (3rd edition), Internet <URL: 1243576599625_0.pdf>

  By the way, when the above-described catheter is punctured into a biological tissue such as an organ and a drug or the like is administered to a medication target such as a tumor in the biological tissue, the biological tissue is arranged so that the through hole does not move in the medication target. The position of the catheter needs to be regulated.

  However, the living body changes its shape and posture according to breathing and exercise, and the shape and position of the living tissue are not always constant and always change accordingly. For this reason, it is desired to reliably position the through hole with respect to the biological tissue of the catheter by absorbing the change caused by the movement of the biological tissue.

  The present invention has been made in view of the above, and an object of the present invention is to provide a catheter that can absorb a change caused by movement of a living tissue and can reliably position a through hole with respect to the living tissue.

  In order to solve the above-described problems and achieve the object, a catheter according to the present invention has an elongated casing having a first lumen and a second lumen inside, and the first end is located on the proximal end side. At least one first through-hole communicating with the first lumen and the second lumen having a first opening for taking fluid into the lumen and a second opening for taking fluid into the second lumen A catheter main body having a second through hole communicating with the first main body, and the catheter main body in a mode that communicates with the second lumen via the second through hole and does not cover the first through hole when inflated. And at least one balloon configured to define the position of the catheter body with respect to the living tissue from the outside of the living tissue when inflated.

  In the catheter according to the present invention, in the above invention, the shape of the balloon when inflated is longer in the maximum length in the direction perpendicular to the axis than in the maximum length in the axial direction of the catheter body. It is characterized by.

  The catheter according to the present invention is characterized in that, in the above-mentioned invention, the shape of the balloon when inflated is a substantially spherical body.

  The catheter according to the present invention is characterized in that, in the above-mentioned invention, the shape of the balloon when inflated is a substantially toroid.

  The catheter according to the present invention is characterized in that, in the above-mentioned invention, the balloon is constituted by a plurality of sub-balloons, each of which is independent.

  The catheter according to the present invention is characterized in that, in the above invention, the tip of the balloon body is a sharp puncture portion.

  In the catheter according to the present invention as set forth in the invention described above, the balloon covers the tip of the balloon body when inflated.

  The catheter according to the present invention is characterized in that, in the above invention, the distal end of the catheter body is an opening.

  In the catheter according to the present invention as set forth in the invention described above, the balloon covers the distal end of the catheter main body and closes the opening when inflated.

  In the catheter according to the present invention, in the above invention, the through hole is located on a side surface of the catheter body, and the balloon is located on the distal end side of the catheter body with respect to the through hole. It is characterized by that.

  The catheter according to the present invention is characterized in that, in the above-mentioned invention, an anchoring portion is disposed on a side surface of the catheter body on the proximal end side with respect to the through hole.

  In the catheter according to the present invention, in the above invention, the through hole is located on a side surface of the catheter body, and the balloon is located on a proximal end side of the catheter body with respect to the through hole. It is characterized by being.

  The catheter according to the present invention is characterized in that, in the above-described invention, an anchoring portion is disposed on a side surface on the distal end side of the through hole of the catheter body.

  In the catheter according to the present invention, in the above invention, the through hole is located on a side surface of the catheter body, and the at least one balloon is located on a distal end side of the catheter body with respect to the through hole. And a second balloon located on the proximal end side.

  In the above invention, the catheter according to the present invention further includes another balloon that can be attached to the distal end of the catheter.

  The catheter according to the present invention is a member that is slidable with respect to the catheter body in the above-described invention, and includes a third lumen and a fourth lumen that is open at both ends through which the catheter body is inserted. And a slide member body having a third opening for taking fluid into the third lumen on the proximal end side, and communicating with the third lumen, fixed to the slide member body, and inflated And a slide member having at least one second balloon configured to define a position of the slide member main body with respect to the living tissue from time to time.

  In the catheter according to the present invention, in the above invention, the balloon is located from the distal end side to the proximal end side of the first through hole, and the first through hole and the outside of the balloon The balloon is provided with a communication passage for communicating the space.

  In the catheter according to the present invention as set forth in the invention described above, the communication path is a slit.

  In the catheter according to the present invention as set forth in the invention described above, the first through hole is provided at a position corresponding to the communication path not covered with the living tissue.

  Further, in the catheter according to the present invention, in the above invention, the balloon has a thickness that corresponds to a portion that is not covered with the biological tissue, compared to a thickness that corresponds to the portion that is covered with the biological tissue. It is thin.

  In the catheter according to the present invention, the first through hole is provided in a portion covered with the living tissue.

  In the catheter according to the present invention as set forth in the invention described above, the balloon is provided at at least one end of a portion not covered with the living tissue.

  According to the present invention, an elongated casing having a first lumen and a second lumen is formed therein, and a first opening for taking fluid into the first lumen and the second lumen are disposed on the proximal end side. A catheter body having a second opening for taking fluid in, and having at least one first through hole communicating with the first lumen and a second through hole communicating with the second lumen; The second lumen is communicated with the second lumen via the second through hole, and is fixed to the catheter body so as not to cover the first through hole at the time of expansion. There is provided a catheter having at least one balloon configured to define a position of the catheter body relative to tissue. Due to the elasticity and resilience of the balloon, it is possible to absorb changes due to the movement of the living tissue and to reliably position the through hole with respect to the living tissue. In addition, the catheter can be easily extracted from the living tissue by extracting the fluid from the balloon and contracting the balloon.

FIG. 1 is a schematic cross-sectional view showing the configuration of the catheter according to the first embodiment of the present invention. FIG. 2 is a perspective view showing the configuration of the catheter shown in FIG. FIG. 3 is a schematic cross-sectional view showing a configuration in which the balloon shape of the catheter according to the first embodiment of the present invention is changed. FIG. 4 is a perspective view showing the configuration of the catheter shown in FIG. FIG. 5 is a schematic cross-sectional view showing a configuration in which the balloon shape obtained by dividing the balloon of the catheter according to the first embodiment of the present invention is changed. FIG. 6 is a perspective view showing a configuration in which the distal end of the catheter of FIG. 1 is open. FIG. 7 is a perspective view showing a configuration of a balloon for closing the distal end of the catheter of FIG. FIG. 8 is a diagram showing an example in which a mooring portion is provided in addition to the balloon. FIG. 9 is a diagram showing another example in which a mooring portion is provided in addition to the balloon. FIG. 10A is a schematic diagram illustrating an example in which the balloon is disposed on the distal end side of the catheter body from the through hole, and the anchoring portion is disposed on the proximal end side of the catheter body from the through hole. FIG. 10-2 is a schematic diagram illustrating an example in which the balloon is disposed on the proximal end side of the catheter main body from the through hole, and the anchoring portion is disposed on the distal end side of the catheter main body from the through hole. FIG. 10C is a diagram illustrating an example in which two balloons are arranged. FIG. 11 is a diagram showing a configuration in which one of two balloons can be separated. FIG. 12 is a diagram showing a configuration in which one of two balloons can be separated and the one balloon can be slidably mounted. FIG. 13 is a diagram illustrating a cross-sectional configuration of the slide member illustrated in FIG. 12. 14 is a view showing a cross-sectional configuration of the catheter body shown in FIG. FIG. 15 is a perspective view showing the configuration of the catheter according to the second embodiment of the present invention. 16 is a cross-sectional view showing a configuration in the vicinity of the through hole of the catheter shown in FIG. FIG. 17 is a cross-sectional view showing a configuration of a modified example of the catheter according to the second embodiment of the present invention.

  Hereinafter, with reference to drawings, the catheter which is a form for carrying out this invention is explained.

(Embodiment 1)
FIG. 1 is a schematic cross-sectional view showing a configuration of a catheter according to Embodiment 1 of the present invention. FIG. 2 is a perspective view showing the configuration of the catheter shown in FIG. 1 and 2, the catheter 1 has a catheter body 2 and a balloon 3. 1A and 2 show a state where the balloon 3 is inflated, and FIG. 1B shows a state where the balloon 3 is deflated.

  The catheter body 2 has an elongated casing having a first lumen 10 and a second lumen 11 therein, and a first opening 7 for taking a fluid such as a drug into the first lumen 10 on the proximal end side. The second lumen 11 has a second opening 8 for taking a fluid such as air or water. In addition, at least one first through hole 5 communicating with the first lumen 10 and a second through hole 9 communicating with the second lumen 11 are formed on the side surface of the catheter body 2. A branch portion 6 is provided at the proximal end portion of the catheter body 2, and the first opening 7 is provided at the proximal end of the branch portion 6. The tip of the catheter body 2 is a sharp puncture portion 4. The catheter body 2 can be formed of a material such as silicon, Teflon (registered trademark), polyvinyl chloride, or polyethylene.

  Here, the fluid that has entered from the first opening 7 passes through the first lumen 10 and is discharged from the first through hole 5 to the outside of the catheter 1. Further, the fluid entering from the second opening 8 passes through the second lumen 11 and reaches the second through hole 9, flows into the balloon 3, and inflates the balloon 3.

  The balloon 3 communicates with the second lumen 11 via the second through hole 9 and is fixed to the catheter body 2 in such a manner that the first through hole 5 is not covered during inflation. The balloon 3 defines the position of the catheter body 2 with respect to the living tissue 12 from the outside of the living tissue 12 when inflated. The balloon 3 is preferably in contact with the living tissue 12 when inflated. The balloon 3 can be formed of, for example, silicon rubber or latex. The balloon 3 only needs to have an aspect that does not cover the first through-hole 5 at the time of inflation, and may be inclined to the first through-hole 5 side. 5 may be covered. In short, it is only necessary that the first through hole is not closed when the balloon 3 is inflated.

  As shown in FIGS. 1 and 2, the balloon 3 has a substantially spherical shape, and the distal end side and the rear end side of the catheter main body 2 are each open, and the catheter main body 2 is inserted through a passage connecting the openings. It has been fixed. In relation to this opening, the balloon 2 is inflated when the maximum length L2 in the direction orthogonal to the axis is longer than the maximum length L1 in the axial direction of the catheter body 2. Due to this shape feature, the living tissue 12 and the balloon 3 come into contact with each other over a wide area. The balloon 3 is deflated when the catheter 1 is punctured into the living tissue 12, but is inflated by the fluid flowing in from the second opening 8 after the puncture.

  The shape of the balloon 3 is not limited to a substantially spherical shape. For example, as in the catheter 1a shown in FIGS. 3 and 4, the substantially spherical balloon 3 may be used instead of the substantially spherical balloon 3. Even in this case, the balloon 15 is inflated when the maximum length L2 in the direction orthogonal to the axis is longer than the maximum length L1 in the axial direction of the catheter body 2.

  Furthermore, it is good also as the balloon 16 comprised from the some subballoon 16a, 16b, 16c which is respectively independent like the catheter 1b shown in FIG. By dividing the balloon 16 into a plurality of sub-balloons 16a to 16c in this way, the amount of fluid necessary for inflating the balloon 16 can be reduced. Even in this case, the shape of the balloon 16 when inflated is longer in the maximum length L2 in the direction orthogonal to the axis than in the maximum length L1 in the axial direction of the catheter body 2.

  Moreover, the opening part 17 may be sufficient as the front-end | tip part of the catheter main body 2 like the catheter 1c shown in FIG. A guide wire 18 can be used using the second opening 8 and the opening 17. FIG. 6 shows a state where the balloon 3 is deflated. In this case, a path for discharging medicine or the like (first opening 7, first lumen 10, first through hole 5) and a path for inflating the balloon 3 (second opening 8, second lumen) 11. In addition to the second through hole 9), a guide wire path (wire insertion opening 18a, guide wire lumen 18b, opening 17) is provided.

  Furthermore, it is good also as the balloon 20 comprised so that the front-end | tip of the catheter main body 2 might be covered at the time of expansion | swelling like the catheter 1d shown in FIG. In this case, when the distal end of the catheter body 2 is the puncture portion 4, the sharp puncture portion 4 is covered with the balloon 20 when inflated, and there is no possibility of damaging the inside of the living body by the puncture portion 4. Further, when the distal end of the catheter body 2 is the opening 17, the balloon 20 when inflated blocks the opening 17. Thereby, it is possible to prevent body fluid or the like from entering the catheter 1d through the opening 17.

  By the way, the above-described catheters 1, 1a to 1d are arranged such that the positions of the catheters 1, 1a to 1d with respect to the living tissue 12 by the balloons 3, 15, 16, and 20 inflated by the fluid 16 and 20 are defined by the contact. However, in addition to this, for example, an anchoring portion such as a flange 21 shown in FIG. 8 or a protrusion 22 shown in FIG. 1d may be moored to the living tissue 12. The flange 21 is preferably not only brought into contact with the living tissue 12 but also anchored by forming a hole 21a through which a suture thread passes as shown in FIG.

  In this case, as shown in FIG. 10A, the balloon 3 is disposed on the distal end side of the catheter body 2 from the through hole 5, and the anchoring portion 31 such as the flange 21 and the protrusion 22 is disposed on the proximal end of the catheter body 2 from the through hole 5. 10-2, the balloon 3 may be disposed on the proximal end side of the catheter body 2 from the through hole 5, and the anchoring portion 31 may be disposed on the distal end side of the catheter body 2 from the through hole 5. You may arrange in. Of course, as shown in FIG. 10-3, the balloon 3 is arranged on the distal end side of the catheter body 2 from the through hole 5, and the balloon 33 corresponding to the balloon 3 is arranged on the proximal end side of the catheter body 2 from the through hole 5. May be. In this case, the living tissue 12 is sandwiched between the two balloons 3 and 33 and positioned.

  When two balloons are used, as shown in FIG. 11, one of the two balloons 3 and 35 is disposed on the proximal end side of the catheter body 2 with respect to the through hole 5, and the other balloon is disposed. 35 may be attachable to the distal end of the catheter body 2. The balloon 35 is attached in an expanded state to a pipe 34 that can be attached to the distal end of the catheter body 2. Then, by attaching the pipe 34 to the distal end of the catheter body 2, the balloon 35 abuts on the living tissue 12, and the catheter body 2 can be positioned.

  The other balloon may be slidably attached to the catheter body 2. That is, as shown in FIG. 12, a balloon 41 fixed to the slide member 40 and a balloon 3 fixed to the catheter body 2 using a slide member 40 that is a member slidable with respect to the catheter body 2. You may make it prescribe | regulate the position of the catheter 1 on both sides of the biological tissue 12. FIG.

  The slide member 40 includes a slide member main body 42. As shown in the cross-sectional view of FIG. 13, the slide member main body 42 has a fourth end in which both ends into which the third lumen 50 and the catheter main body 2 are inserted are opened. It has a long and narrow casing having a lumen 51, and includes a branch portion 43 having a third opening 44 for taking a fluid into the third lumen 50 on the proximal end side. The balloon 41 communicates with the third lumen 50 and is fixed to the slide member main body 42. The balloon 41 defines the position of the slide member 40 with respect to the living tissue 12 from the outside of the living tissue 12 when inflated, like the balloon 3. As a result, it is possible to deal with living tissue 12 of various sizes.

  On the other hand, the catheter body 2 to which the slide member 40 is attached is inflated with a first lumen 52 for a medicine and the like and a balloon 3 attached to the distal end side of the catheter body 2 as shown in the cross-sectional view of FIG. A second lumen 53 for guiding the guide wire and a lumen 54 for passing the guide wire. The first lumen 52 communicates the first opening 47 for medicine and the through hole 5 formed at the proximal end of the branching portion 46 provided on the proximal end side of the catheter body 2. In addition, the second lumen 53 communicates the second opening 48 for inflating the balloon 3 formed at the proximal end of the branch portion 49 provided on the proximal end side of the catheter body 2 and the inside of the balloon 3. Let Furthermore, an opening 45 for a guide wire is formed at the proximal end of the catheter body 2, and the distal end and the proximal end of the catheter body 2 are communicated by a lumen (not shown) so that the guide wire can be inserted.

  Here, the slide member 40 is combined with the catheter body 2 from the distal end side of the catheter 1 with at least the balloon 3 deflated. As a result, as shown in FIG. 12B, the through-hole 5 is formed by the balloon 3 provided at the distal end of the catheter body 2 and the balloon 41 provided on the distal end side of the slide member 40 movable in the axial direction. The catheter body 2 and the slide member 40 are positioned with the living tissue 12 in which is placed. In this case, each balloon 3, 41 can be inflated independently.

  In the first embodiment, the catheter body 2 can be positioned with respect to the living tissue 12 by at least the balloon 3, and the balloon 3 absorbs changes due to the movement of the living tissue 12 and other living tissues, thereby positioning the catheter 1. Can be performed reliably.

(Embodiment 2)
Next, a second embodiment of the present invention will be described. In the first embodiment described above, one balloon is in contact with one end of the living tissue to position the catheter, but in this second embodiment, one balloon is in contact with both ends of the living tissue and the catheter is positioned. Like to do.

  FIG. 15 is a perspective view showing the configuration of the catheter according to the second embodiment of the present invention. FIG. 16 is a cross-sectional view showing a state in which the balloon of the catheter shown in FIG. 15 is arranged in the living tissue. As shown in FIGS. 15 and 16, the balloon 103 provided in the catheter body 2 is located from the distal end side to the proximal end side of the first through hole 5, and the first through hole 5 and the balloon 103 are located. A slit 110 is provided as a communication path that communicates the space with the outside. That is, at the position corresponding to the slit 110, the living body tissue 12 is in direct contact with the living body tissue 12 through the through-hole 5 from the lumen for discharging the medicine or the like without the balloon 103, or a space is formed between the living body tissue 12 To do. Through holes 9 are provided in the side surfaces of the catheter body 2 at both axial ends of the balloon 103, and a fluid for inflating the balloon 103 flows in.

  Then, when the catheter body 2 is punctured (penetrated) into the biological tissue 12 and fluid is introduced through the through-hole 9 to inflate the balloon 103, the biological tissue 12 is obtained as shown in FIGS. A portion of the balloon 103 located outside is mainly inflated, and the living tissue 12 and the balloon 103 are in close contact with each other. As a result, the catheter body 2 is positioned with respect to the living tissue 12, and the balloon 103 absorbs changes due to the movement of the living tissue 12 and other living tissues, so that the catheter 101 can be positioned reliably.

  As shown in FIG. 16, the balloon 103 has a thickness (balloon film thickness) of a portion E2 where the balloon 103 is not covered with the biological tissue 12 as compared with a portion E1 where the balloon 103 is covered with the biological tissue 12. It is preferable to keep it thin. As a result, the portion of the balloon 103 that is not covered by the biological tissue 12 can be easily inflated in a direction perpendicular to the axial direction of the catheter body 2, and the contact area between the balloon 103 and the biological tissue 12 can be increased. 101 can be stably positioned.

  As shown in FIG. 17, a through hole 120 may be used instead of the slit 110. In this case, similarly to the slit 110, a gap is easily generated between the living tissue 12 and the through hole 5, so that the medicine or the like can be reliably discharged, and clogging of the through hole 5 due to the medicine or the like can be prevented. Can be reduced.

  In the above-described embodiment, only the balloon is inflated. However, all of these balloons can be contracted by sucking the fluid in the balloon, and the catheter can be easily pulled out of the body. it can.

1, 1a to 1d, 101 Catheter 2 Catheter body 3, 15, 16, 20, 33, 35, 41, 103 Balloon 4 Puncture part 5, 9, 120 Through hole 6, 43, 46, 49 Branch part 7 First Opening 8 Second opening 10, 52 First lumen 11, 53 Second lumen 12 Biological tissue 16a-16c Sub-balloon 17, 44, 45, 47, 48 Opening 18 Guide wire 18a Wire insertion opening 18b For guide wire Lumen 21 Flange 22 Protrusion 31 Anchoring portion 34 Pipe 40 Slide member 42 Slide member main body 50 Third lumen 51 Fourth lumen 54 Lumen 110 Slit
L1, L2 maximum length

Claims (22)

A long and narrow housing having a first lumen and a second lumen therein, a first opening for taking fluid into the first lumen and a second for taking fluid into the second lumen on the proximal end side A catheter body having at least one first through hole communicating with the first lumen and a second through hole communicating with the second lumen;
The second lumen is communicated with the second lumen via the second through hole, and is fixed to the catheter body in a manner that does not cover the first through hole during expansion, and the living body from outside the living tissue during expansion. At least one balloon configured to define a position of the catheter body relative to tissue;
A catheter characterized by comprising:   2. The catheter according to claim 1, wherein the balloon is inflated when the maximum length in the direction orthogonal to the axis is longer than the maximum length in the axial direction of the catheter body.   The catheter according to claim 1, wherein the balloon has a substantially spherical shape when inflated.   2. The catheter according to claim 1, wherein a shape of the balloon when inflated is a substantially torus.   The catheter according to claim 1, wherein the balloon includes a plurality of sub-balloons that are independent of each other.   The catheter according to claim 1, wherein the tip of the balloon body is a sharp puncture portion.   The catheter according to claim 6, wherein the balloon covers the tip of the balloon body when inflated.   The catheter according to claim 1, wherein the distal end of the catheter body is an opening.   The catheter according to claim 8, wherein the balloon covers the distal end of the catheter body and closes the opening when inflated. The through hole is located on a side surface of the catheter body;
The catheter according to claim 1, wherein the balloon is located on a distal end side of the catheter body with respect to the through hole.   The catheter according to claim 10, wherein an anchoring portion is disposed on a side surface on the proximal end side with respect to the through hole of the catheter body. The through hole is located on a side surface of the catheter body;
The catheter according to claim 1, wherein the balloon is located on a proximal end side of the catheter body with respect to the through hole.   The catheter according to claim 12, wherein an anchoring portion is disposed on a side surface of the catheter body on the distal end side with respect to the through hole. The through hole is located on a side surface of the catheter body;
The at least one balloon includes a first balloon positioned on a distal end side of the catheter body with respect to the through hole and a second balloon positioned on a proximal end side. Item 10. The catheter according to Item 1.   The catheter according to claim 1, further comprising another balloon attachable to the catheter tip. A member that is slidable with respect to the catheter body, and has an elongated casing having a third lumen and a fourth lumen open at both ends through which the catheter body is inserted; A slide member body having a third opening for taking fluid into the three lumens;
At least one second balloon in communication with the third lumen, fixed to the slide member body, and configured to define a position of the slide member body relative to the living tissue from outside the living tissue when inflated; ,
The catheter according to claim 1, further comprising a slide member having the following.   The balloon is located from the distal end side to the proximal end side of the first through hole, and a communication path is provided in the balloon for communicating the space between the first through hole and the outside of the balloon. The catheter according to claim 1.   The catheter according to claim 17, wherein the communication path is a slit.   The catheter according to claim 17, wherein the first through hole is provided at a position corresponding to the communication path that is not covered with the living tissue.   18. The balloon according to claim 17, wherein a thickness of a portion corresponding to a portion not covered with the biological tissue is smaller than a thickness of a portion corresponding to the portion covered with the biological tissue. catheter.   The catheter according to claim 1, wherein the first through hole is provided in a portion covered with the living tissue.   The catheter according to claim 1, wherein the balloon is provided at at least one end of a portion not covered with the living tissue.

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