JP2010222585A - 曇りの無いセルロースエーテルカプセルおよび作製方法 - Google Patents
曇りの無いセルロースエーテルカプセルおよび作製方法 Download PDFInfo
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- JP2010222585A JP2010222585A JP2010088970A JP2010088970A JP2010222585A JP 2010222585 A JP2010222585 A JP 2010222585A JP 2010088970 A JP2010088970 A JP 2010088970A JP 2010088970 A JP2010088970 A JP 2010088970A JP 2010222585 A JP2010222585 A JP 2010222585A
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- JP
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- Prior art keywords
- cellulose ether
- composition
- weight
- cellulose
- depolymerized
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 229920003086 cellulose ether Polymers 0.000 title claims abstract description 106
- 238000000034 method Methods 0.000 title claims abstract description 31
- 239000002775 capsule Substances 0.000 title abstract description 30
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 42
- 239000000203 mixture Substances 0.000 claims abstract description 33
- 239000011780 sodium chloride Substances 0.000 claims abstract description 21
- 239000000243 solution Substances 0.000 claims abstract description 19
- 239000007864 aqueous solution Substances 0.000 claims abstract description 10
- 238000000576 coating method Methods 0.000 claims abstract description 7
- 239000011248 coating agent Substances 0.000 claims abstract description 6
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 19
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 18
- 229910000041 hydrogen chloride Inorganic materials 0.000 claims description 18
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 claims description 18
- NEHMKBQYUWJMIP-UHFFFAOYSA-N chloromethane Chemical group ClC NEHMKBQYUWJMIP-UHFFFAOYSA-N 0.000 claims description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims description 13
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims description 13
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims description 11
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims description 11
- 229920000609 methyl cellulose Polymers 0.000 claims description 11
- 239000001923 methylcellulose Substances 0.000 claims description 11
- 229920002678 cellulose Polymers 0.000 claims description 9
- 239000001913 cellulose Substances 0.000 claims description 9
- 238000005406 washing Methods 0.000 claims description 8
- 229940050176 methyl chloride Drugs 0.000 claims description 7
- 150000003388 sodium compounds Chemical class 0.000 claims description 7
- 239000006227 byproduct Substances 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- 238000001035 drying Methods 0.000 claims description 5
- 238000004519 manufacturing process Methods 0.000 claims description 5
- 229910052751 metal Inorganic materials 0.000 claims description 5
- 239000002184 metal Substances 0.000 claims description 5
- 238000003801 milling Methods 0.000 claims description 5
- 230000003113 alkalizing effect Effects 0.000 claims description 4
- 238000003618 dip coating Methods 0.000 claims description 4
- GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical compound CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 claims description 3
- 230000003472 neutralizing effect Effects 0.000 claims description 3
- FGUUSXIOTUKUDN-IBGZPJMESA-N C1(=CC=CC=C1)N1C2=C(NC([C@H](C1)NC=1OC(=NN=1)C1=CC=CC=C1)=O)C=CC=C2 Chemical compound C1(=CC=CC=C1)N1C2=C(NC([C@H](C1)NC=1OC(=NN=1)C1=CC=CC=C1)=O)C=CC=C2 FGUUSXIOTUKUDN-IBGZPJMESA-N 0.000 claims description 2
- 230000015572 biosynthetic process Effects 0.000 abstract description 8
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 8
- 238000006243 chemical reaction Methods 0.000 description 8
- 150000003839 salts Chemical class 0.000 description 7
- 239000003814 drug Substances 0.000 description 6
- 229940079593 drug Drugs 0.000 description 6
- 239000002253 acid Substances 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- 235000017557 sodium bicarbonate Nutrition 0.000 description 4
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 4
- 239000010409 thin film Substances 0.000 description 4
- 238000006266 etherification reaction Methods 0.000 description 3
- 239000012467 final product Substances 0.000 description 3
- 238000006386 neutralization reaction Methods 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 230000035484 reaction time Effects 0.000 description 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- LCGLNKUTAGEVQW-UHFFFAOYSA-N Dimethyl ether Chemical compound COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 description 2
- 108010010803 Gelatin Proteins 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 238000012691 depolymerization reaction Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000008273 gelatin Substances 0.000 description 2
- 229920000159 gelatin Polymers 0.000 description 2
- 235000019322 gelatine Nutrition 0.000 description 2
- 235000011852 gelatine desserts Nutrition 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 239000011261 inert gas Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 238000011144 upstream manufacturing Methods 0.000 description 2
- RPZANUYHRMRTTE-UHFFFAOYSA-N 2,3,4-trimethoxy-6-(methoxymethyl)-5-[3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxyoxane;1-[[3,4,5-tris(2-hydroxybutoxy)-6-[4,5,6-tris(2-hydroxybutoxy)-2-(2-hydroxybutoxymethyl)oxan-3-yl]oxyoxan-2-yl]methoxy]butan-2-ol Chemical compound COC1C(OC)C(OC)C(COC)OC1OC1C(OC)C(OC)C(OC)OC1COC.CCC(O)COC1C(OCC(O)CC)C(OCC(O)CC)C(COCC(O)CC)OC1OC1C(OCC(O)CC)C(OCC(O)CC)C(OCC(O)CC)OC1COCC(O)CC RPZANUYHRMRTTE-UHFFFAOYSA-N 0.000 description 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- 229920001479 Hydroxyethyl methyl cellulose Polymers 0.000 description 1
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 150000001350 alkyl halides Chemical class 0.000 description 1
- 229940045720 antineoplastic alkylating drug epoxides Drugs 0.000 description 1
- 238000009993 causticizing Methods 0.000 description 1
- HRYZWHHZPQKTII-UHFFFAOYSA-N chloroethane Chemical compound CCCl HRYZWHHZPQKTII-UHFFFAOYSA-N 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 229960003750 ethyl chloride Drugs 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 239000007903 gelatin capsule Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 description 1
- 239000002932 luster Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 150000002924 oxiranes Chemical class 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000009492 tablet coating Methods 0.000 description 1
- 239000002700 tablet coating Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B11/00—Preparation of cellulose ethers
- C08B11/20—Post-etherification treatments of chemical or physical type, e.g. mixed etherification in two steps, including purification
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
- C08L1/08—Cellulose derivatives
- C08L1/26—Cellulose ethers
- C08L1/28—Alkyl ethers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
【解決手段】20℃でパーセント水溶液において約200mPas以下の粘度の低分子量セルロースエーテル及び、セルロースエーテル重量に対し、塩化ナトリウムが約0.3重量%(質量%)以下の含有量からなる組成物であり、組成物からなるコーティング溶液からからなる著しく低減された曇り形成を示すカプセル、およびそのカプセルを作成するための製造方法。
【選択図】なし
Description
a)水酸化ナトリウムをそれに接触させることによって、セルロースパルプをアルカリ化し;
b)そのセルロースパルプをエーテル化して、セルロースエーテルを形成し;
c)そのセルロースエーテルを洗浄して、塩化ナトリウム含有量を低減し;
d)低減された含水量にセルロースエーテルを乾燥し;
e)セルロースエーテルを粒子形にミリングし;
f)その2パーセント水溶液が20℃における200cP以下の粘度を有するように、それを部分的に解重合するために充分な塩化水素の量と、粒状のセルロースエーテルとを接触させ;
g)その粒状のセルロースエーテルを塩基性ナトリウム化合物と接触させることにより、部分的にまたは実質的に塩化水素を中和することを含み;解重合されたセルロースエーテルの重量に基き、解重合されたセルロースエーテルの塩化ナトリウム含有量を約0.3重量%(質量%)以下に制限するために充分な程度に、ステップc)においてセルロースエーテルを洗浄し、その程度にステップf)において塩化水素の量を調節する製造方法。
Claims (3)
- セルロースエーテル組成物であって;その組成物は、20℃で2パーセント水溶液において200mPa・s以下の粘度を有する低分子量セルロースエーテルを含み;該組成物は、メチルセルロースまたはヒドロキシプロピルメチルセルロースを含み;且つ、セルロースエーテル重量に基き0.3重量パーセント(質量%)以下の塩化ナトリウム含有量を有する。
- 前記組成物が、セルロースエーテル重量に基き0.15重量%(質量%)以下の塩化ナトリウム含有量を有する請求項1の組成物。
- セルロースエーテル組成物の製造方法であって;その方法が:
a)水酸化ナトリウムをそれに接触させることによって、セルロースパルプをアルカリ化し;
b)そのセルロースパルプをエーテル化して、セルロースエーテルを形成し;エーテル化剤が、メチルセルロースを形成するための塩化メチル;または、ヒドロキシプロピルメチルセルロースを形成するための、塩化メチルおよびプロピレンオキシドの混合物であり;
c)そのセルロースエーテルを洗浄して、アルカリ化剤としての水酸化ナトリウムとエーテル化剤としての塩化メチルの使用により形成された副生成物としての塩化ナトリウム含有量を低減し;
d)低減された含水量に、メチルセルロースまたはヒドロキシプロピルメチルセルロースであるセルロースエーテルを乾燥し;
e)セルロースエーテルを粒子形にミリングし;
f)その2パーセント水溶液が20℃における200mPa・s以下の粘度を有するように、それを部分的に解重合するために充分な塩化水素の量と、粒状のセルロースエーテルとを接触させ;
g)その粒状のセルロースエーテルを塩基性ナトリウム化合物と接触させることにより、部分的にまたは実質的に塩化水素を中和することを含み;解重合されたセルロースエーテルの重量に基き、解重合されたセルロースエーテルの塩化ナトリウム含有量を0.3重量%(質量%)以下に制限するために充分な程度に、ステップc)においてセルロースエーテルを洗浄し、その程度にステップf)において塩化水素の量を調節し;
h)解重合されたセルロースエーテルを水中に溶解して、浸漬コーティング溶液を形成し;
i)金属ピンを、そのコーティング溶液に浸し;
j)前記金属ピンをコーティング溶液から取り出し、その溶液をゲル化させ、次いで、ピン表面で乾燥させて、キャップおよび/又は本体を形成し;
k)そのキャップおよび/又は本体を、ピンから取り外す製造方法。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/295,692 US6294008B1 (en) | 1999-04-21 | 1999-04-21 | Haze-free cellulose ether capsules and process for making |
US09/295,692 | 1999-04-21 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2000612340A Division JP2002541945A (ja) | 1999-04-21 | 2000-04-12 | 曇りの無いセルロースエーテルカプセルおよび作製方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2010222585A true JP2010222585A (ja) | 2010-10-07 |
JP4746139B2 JP4746139B2 (ja) | 2011-08-10 |
Family
ID=23138829
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2000612340A Withdrawn JP2002541945A (ja) | 1999-04-21 | 2000-04-12 | 曇りの無いセルロースエーテルカプセルおよび作製方法 |
JP2010088970A Expired - Lifetime JP4746139B2 (ja) | 1999-04-21 | 2010-04-07 | 曇りの無いセルロースエーテルカプセルおよび作製方法 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2000612340A Withdrawn JP2002541945A (ja) | 1999-04-21 | 2000-04-12 | 曇りの無いセルロースエーテルカプセルおよび作製方法 |
Country Status (12)
Country | Link |
---|---|
US (1) | US6294008B1 (ja) |
EP (1) | EP1173487B1 (ja) |
JP (2) | JP2002541945A (ja) |
AR (1) | AR028147A1 (ja) |
AT (1) | ATE338066T1 (ja) |
AU (1) | AU759877B2 (ja) |
BR (1) | BR0011141B1 (ja) |
CA (1) | CA2370294C (ja) |
CO (1) | CO5170467A1 (ja) |
DE (1) | DE60030425T2 (ja) |
ES (1) | ES2265937T3 (ja) |
WO (1) | WO2000063254A1 (ja) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0314832D0 (en) * | 2003-06-25 | 2003-07-30 | Phoqus Pharmaceuticals Ltd | Production of capsule shells and capsules |
US7703456B2 (en) | 2003-12-18 | 2010-04-27 | Kimberly-Clark Worldwide, Inc. | Facemasks containing an anti-fog / anti-glare composition |
EP1758938B1 (en) * | 2004-05-26 | 2019-05-15 | Dow Global Technologies LLC | Production of low molecular weight ethylcellulose |
EP2325247B1 (en) * | 2007-11-09 | 2014-10-08 | Dow Global Technologies LLC | Cellulose ether coating compositions and method |
PL2480218T3 (pl) | 2009-09-24 | 2020-11-16 | Capsugel Belgium Nv | Kapsułki odporne na kwas |
FR2953217B1 (fr) * | 2009-11-27 | 2012-10-05 | Ifremer | Procede de depolymerisation de polysaccharides par broyage mecanique |
US9156919B2 (en) | 2011-07-27 | 2015-10-13 | Dow Global Technologies Llc | Method of removing alkylene halogenohydrin from cellulose ether |
KR101951290B1 (ko) | 2012-04-18 | 2019-02-22 | 롯데정밀화학 주식회사 | 필름 및 그의 제조방법 |
JP7267992B2 (ja) | 2017-08-16 | 2023-05-02 | ニュートリション アンド バイオサイエンシズ ユーエスエー 1,リミティド ライアビリティ カンパニー | 低分子量セルロースエーテルの制御された調製方法 |
JP7414685B2 (ja) * | 2020-10-22 | 2024-01-16 | 信越化学工業株式会社 | 解重合されたセルロースエーテルの製造方法 |
JP7414686B2 (ja) | 2020-10-22 | 2024-01-16 | 信越化学工業株式会社 | 解重合されたセルロースエーテルの製造方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4841037B1 (ja) * | 1964-10-26 | 1973-12-04 | ||
JPS6253301A (ja) * | 1985-08-29 | 1987-03-09 | ヘキスト・アクチエンゲゼルシヤフト | 低粘度セルロ−スエ−テルの製造法 |
JPH08176201A (ja) * | 1994-09-26 | 1996-07-09 | Hoechst Ag | 低分子量セルロースエーテルの製造方法 |
JPH08301901A (ja) * | 1995-05-12 | 1996-11-19 | Shin Etsu Chem Co Ltd | 低重合度セルロースエーテルの製造方法 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4001211A (en) | 1974-12-02 | 1977-01-04 | The Dow Chemical Company | Pharmaceutical capsules from improved thermogelling methyl cellulose ethers |
US4229572A (en) * | 1979-03-05 | 1980-10-21 | The Dow Chemical Company | Purification of cellulose ether reaction product |
DE2912486A1 (de) * | 1979-03-29 | 1980-10-09 | Henkel Kgaa | Verfahren zum reinigen von kaltwasserloeslichen celluloseethern und verwendung der gereinigten produkte, insbesondere in wasch- und reinigungsmitteln |
DE2929011A1 (de) * | 1979-07-18 | 1981-02-12 | Henkel Kgaa | Herstellung von alkylcellulose nach kontinuierlicher verfahrensweise |
DE3043621A1 (de) * | 1980-11-19 | 1982-07-08 | Bayer Ag, 5090 Leverkusen | Reinigung von cellulose- und staerkeethern |
DE3044696A1 (de) * | 1980-11-27 | 1982-06-24 | Bayer Ag, 5090 Leverkusen | Reinigung von cellulose- und staerkeethern |
JPS6225101A (ja) | 1985-07-24 | 1987-02-03 | Shin Etsu Chem Co Ltd | 低重合度セルロ−スエ−テルの製造方法 |
US4988807A (en) | 1989-01-23 | 1991-01-29 | The Dow Chemical Company | Removal of undesirable material from water-soluble polysaccharide ethers |
US5543162A (en) | 1989-02-10 | 1996-08-06 | Alko Group Ltd. | Polymeric capsules, method of making the same, and foodstuffs containing the same |
US5264223A (en) | 1990-03-29 | 1993-11-23 | Japan Elanco Company, Ltd. | Hard capsule for pharmaceutical drugs and method for producing the same |
DE4112849A1 (de) | 1990-04-26 | 1991-10-31 | Hoechst Ag | Verfahren zum abtrennen und reinigen von celluloseethern aus einer celluloseethersuspension |
US5591455A (en) | 1990-12-20 | 1997-01-07 | Warner-Jenkinson Company, Inc. | Wet powder film-forming compositions |
US5218107A (en) | 1991-12-30 | 1993-06-08 | The Dow Chemical Company | Removal of undesirable material from water-soluble cellulose ether aqueous solutions |
US5431917A (en) | 1992-10-08 | 1995-07-11 | Japan Elanco Company, Ltd. | Hard capsule for pharmaceutical drugs and method for producing the same |
DE19633826C1 (de) | 1996-08-22 | 1997-10-30 | Clariant Gmbh | Verfahren zur Herstellung von wasserlöslichen Celluloseethern unter Rückgewinnung von Natriumhydroxid |
-
1999
- 1999-04-21 US US09/295,692 patent/US6294008B1/en not_active Expired - Lifetime
-
2000
- 2000-04-12 EP EP00925943A patent/EP1173487B1/en not_active Expired - Lifetime
- 2000-04-12 AT AT00925943T patent/ATE338066T1/de not_active IP Right Cessation
- 2000-04-12 ES ES00925943T patent/ES2265937T3/es not_active Expired - Lifetime
- 2000-04-12 AU AU44558/00A patent/AU759877B2/en not_active Ceased
- 2000-04-12 DE DE60030425T patent/DE60030425T2/de not_active Expired - Lifetime
- 2000-04-12 WO PCT/US2000/009787 patent/WO2000063254A1/en active IP Right Grant
- 2000-04-12 JP JP2000612340A patent/JP2002541945A/ja not_active Withdrawn
- 2000-04-12 CA CA002370294A patent/CA2370294C/en not_active Expired - Lifetime
- 2000-04-12 BR BRPI0011141-4A patent/BR0011141B1/pt not_active IP Right Cessation
- 2000-04-19 AR ARP000101884A patent/AR028147A1/es active IP Right Grant
- 2000-04-19 CO CO00029095A patent/CO5170467A1/es active IP Right Grant
-
2010
- 2010-04-07 JP JP2010088970A patent/JP4746139B2/ja not_active Expired - Lifetime
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4841037B1 (ja) * | 1964-10-26 | 1973-12-04 | ||
JPS6253301A (ja) * | 1985-08-29 | 1987-03-09 | ヘキスト・アクチエンゲゼルシヤフト | 低粘度セルロ−スエ−テルの製造法 |
JPH08176201A (ja) * | 1994-09-26 | 1996-07-09 | Hoechst Ag | 低分子量セルロースエーテルの製造方法 |
JPH08301901A (ja) * | 1995-05-12 | 1996-11-19 | Shin Etsu Chem Co Ltd | 低重合度セルロースエーテルの製造方法 |
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Publication number | Publication date |
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EP1173487B1 (en) | 2006-08-30 |
AU759877B2 (en) | 2003-05-01 |
CO5170467A1 (es) | 2002-06-27 |
BR0011141B1 (pt) | 2010-12-28 |
CA2370294A1 (en) | 2000-10-26 |
JP4746139B2 (ja) | 2011-08-10 |
BR0011141A (pt) | 2002-02-26 |
ES2265937T3 (es) | 2007-03-01 |
CA2370294C (en) | 2008-12-02 |
US6294008B1 (en) | 2001-09-25 |
JP2002541945A (ja) | 2002-12-10 |
ATE338066T1 (de) | 2006-09-15 |
EP1173487A1 (en) | 2002-01-23 |
DE60030425T2 (de) | 2006-12-14 |
AR028147A1 (es) | 2003-04-30 |
WO2000063254A1 (en) | 2000-10-26 |
AU4455800A (en) | 2000-11-02 |
DE60030425D1 (de) | 2006-10-12 |
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