JP2010214003A - Liquid storage container - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a liquid storage container keeping the inside of a hollow part in an aseptic state and preventing the deformation of a thin film part in high-pressure steam sterilization. <P>SOLUTION: The liquid storage container includes a container body 80 for storing liquid inside; the thin film part 804 formed at a part of the container body 80: a projecting part projected toward the outside of the container body 80 from the peripheral edge part of the thin film part 804 and having a hollow part 803 opened on the tip side; a cap body 82 detachably mounted to the tip side of the projecting part 801 to seal the hollow part 803; and a regulating member 83 for regulating the deformation of the thin film part 804 to the hollow part 803 side in the mounted state of the cap body 82. <P>COPYRIGHT: (C)2010,JPO&INPIT

Description

  The present invention relates to a liquid container.

  Conventionally, a chemical solution storage container (medical container) in which a thin film (thin film portion) that can be pierced by a puncture needle is formed in a part of a container body has been disclosed (for example, see Patent Document 1). In the liquid container disclosed in Patent Document 1, the opening (hollow part) of the container mouth part (protruding part) protruding from the periphery of the thin film is covered with a tab (cap body), and the hollow part is sealed. Taking out the chemical (liquid) from the container body with a syringe or the like is performed by piercing the thin film portion with a puncture needle after removing the cap body. Moreover, in the liquid container disclosed in Patent Document 1, it is necessary to keep the inside of the hollow portion in a sterile state in order to prevent infection due to contact with the thin film portion and the protruding portion of the puncture needle. As a method for making the hollow portion aseptic, for example, high-pressure steam sterilization treatment is performed in which water vapor is sprayed under high pressure conditions in an apparatus such as an autoclave in a state where the hollow portion is sealed with a cap body.

JP 2000-70336 A

  However, the liquid container disclosed in Patent Document 1 may be deformed or damaged in the thin film portion when high-pressure steam sterilization is performed in a state where the hollow portion is sealed with a cap body. Therefore, there is a demand for a liquid container that does not deform the thin film portion even when the high-pressure steam sterilization treatment is performed.

  An object of the present invention is to provide a liquid storage container that can keep the inside of a hollow part aseptic and prevent deformation of a thin film part in high-pressure steam sterilization.

  The present invention includes a container main body in which a liquid is stored, a thin film portion formed in a part of the container main body, a peripheral portion of the thin film portion protruding toward the outside of the container main body, and a distal end side opened. A projecting portion having a hollow portion, a cap body detachably attached to the distal end side of the projecting portion, and the cap body sealing the hollow portion; The above object is achieved by providing a liquid container including a regulating member that regulates deformation.

  The restricting member is disposed at a position facing the thin film portion, and has a stopper portion that contacts at least the thin film portion when the thin film portion is deformed, and the stopper portion is formed in substantially the same shape as the thin film portion. It is preferable.

  The regulating member is disposed at a position facing the thin film portion, and has a stopper portion that contacts at least the thin film portion when the thin film portion is deformed, and the stopper portion is preferably formed in a substantially cross shape. .

  Moreover, it is preferable that the said limitation member is formed in the substantially same shape as the said hollow part.

  Further, it is preferable that the restricting member is connected to the cap body.

  The present invention includes a container main body in which a liquid is stored, a thin film portion formed in a part of the container main body, a peripheral portion of the thin film portion protruding toward the outside of the container main body, and a distal end side opened. Provided is a liquid storage container comprising: a protruding portion having a hollow portion, a cap body that is detachably attached to a distal end side of the protruding portion, and seals the hollow portion; and a ventilation filter provided in the cap body. This achieves the above object.

  ADVANTAGE OF THE INVENTION According to this invention, while keeping the inside of a hollow part aseptically, the liquid container which can prevent a deformation | transformation of a thin film part in a high pressure steam sterilization process can be provided.

It is a schematic diagram which shows a blood component separation accommodation apparatus. It is sectional drawing which shows the component accommodating part shown in FIG. It is sectional drawing which shows the component storage container of this invention. It is a figure which shows a mode that a cap body is attached to a protrusion part. It is a figure which shows the modification of a control member, (a) is a 1st modification, (b) is a figure which shows a 2nd modification. It is a figure which shows 2nd Embodiment of this invention.

  Hereinafter, the liquid container according to the present invention will be described based on preferred embodiments thereof with reference to the drawings. In the first embodiment, the present invention is applied to a component storage container 8 of a blood component separation and storage device 1 that aseptically separates and stores a liquid component (for example, serum) from blood collected from a subject. is there. FIG. 1 is a schematic diagram showing a blood component separation / accommodation apparatus 1. FIG. 2 is a cross-sectional view showing the component storage portion 3 shown in FIG. FIG. 3 is a cross-sectional view showing the component storage container 8 of the present invention. FIG. 4 is a diagram showing how the cap body 82 is attached to the protruding portion 801. 5A and 5B are diagrams showing a modification of the regulating member 83, where FIG. 5A is a first modification, and FIG. 5B is a diagram showing a second modification.

  As shown in FIG. 1, the blood component separation and storage device 1 stores a blood storage part 2 that stores blood and at least a part of a liquid component (liquid) of the blood stored in the blood storage part 2. The component storage part 3 and the connection part 4 which connects the blood storage part 2 and the component storage part 3 aseptically are provided.

As shown in FIG. 1, the blood reservoir 2 stores blood collected from a subject by a blood collection needle 10 via a blood collection tube 11. The blood reservoir 2 is aseptically connected to the blood reservoir 2, and at least a part of the liquid component of the blood stored in the blood reservoir 2 is contained in the component via the connector 4. Part 3 is accommodated.
The connection part 4 is comprised with a connection tube. The connection tube 4 has one end connected to the blood reservoir 2 and the other end connected to the component storage unit 3.

  As shown in FIG. 2, the component storage unit 3 includes an external storage container 7, a component storage container 8 stored in the external storage container 7, and a cover cap 9 attached to the external storage container 7. .

  The external container 7 has a vertically long cylindrical shape, and is configured to be slightly larger than the component container 8 in both diameter and height. An opening is formed at the upper end which is one end of the external container 7. A screw thread 71 is formed on the outer surface in the vicinity of the upper end of the external container 7.

  The cover cap 9 is formed in a cylindrical shape and has an upper surface portion 90 and a side surface portion 91. A first opening 92 having an outer diameter concentric with the outer diameter of the cover cap 9 is formed in the upper surface portion 90 at the center. The side surface portion 91 is formed to protrude downward from the entire circumference of the upper surface portion 90. On the inner wall surface of the side surface portion 91, a screw groove 93 corresponding to the screw thread 71 formed in the external storage container 7 is formed.

  As shown in FIG. 3, the component storage container 8 protrudes from the storage container body 80, a plug 81 attached to the storage container body 80, a thin film portion 804 formed on the storage container body 80, and the storage container body 80. A cylindrical portion 801 as a projecting portion, a cap body 82 attached to the cylindrical portion 801, and a regulating member 83 coupled to the cap body 82.

  The container main body 80 has a vertically long cylindrical shape, and has a first hollow portion 800 therein. An upper end that is one end is provided with an opening that opens the first hollow portion 800, and a lower end that is the other end is closed. Has been. The container main body 80 is made of a material having flexible side and bottom surfaces. As a material having flexibility, soft synthetic resins such as polyvinyl chloride, polyethylene, polypropylene, polyurethane, silicone, ethylene vinyl acetate copolymer resin, synthetic rubber, and various elastomers can be used. Moreover, it is preferable to comprise the side surface of the component storage container 8 from the material which has transparency from a viewpoint which makes the liquid stored in the component storage container 8 visible.

  The thin film portion 804 is formed by providing a thin film-like thin region on a part of the bottom surface of the container main body 80. The thin film portion 804 is formed to be thin enough to be punctured with a puncture device such as an injection needle.

  The cylindrical portion 801 protrudes from the peripheral edge of the thin film portion 804 toward the outside of the container main body 80. The cylindrical portion 801 is formed in a cylindrical shape having a second hollow portion 803 serving as a hollow portion with an open end on the inside. On the inner wall surface of the cylindrical portion 801, an uneven portion 802 that forms unevenness on the inner side of the cylindrical portion 801 is formed.

  As shown in FIGS. 2 to 4, the cap body 82 includes a bottom portion 820, a peripheral edge portion 821, and an opening / closing operation piece 823. The bottom portion 820 is formed in a circular shape so as to cover the tip of the cylindrical portion 801. The peripheral edge 821 protrudes substantially perpendicularly to the bottom 820 from the entire outer periphery of the bottom 820. The opening / closing operation piece 823 is formed such that a bottom portion 820 extends to one side. The cap body 82 is configured such that the bottom portion 820 covers the tip of the cylindrical portion 801 and the peripheral portion 821 covers the side surface on the tip side of the cylindrical portion 801 so that the second hollow portion 803 of the cylindrical portion 801 can be sealed. The cap body 82 described above is made of a thermoplastic resin.

  Further, the cap body 82 is formed with a thin portion 824 that is thinly formed at a circumferential portion at the boundary between the bottom portion 820 and the peripheral edge portion 821. When removing the cap body 82 from the cylindrical portion 801 in the step of collecting the liquid component accommodated in the container main body 80, the cap body 82 can be removed by breaking the thin-walled portion 824 by tensile stress.

  The regulating member 83 is connected to the surface of the bottom portion 820 of the cap body 82 on the side where the peripheral edge portion 821 projects. The restricting member 83 includes a stopper portion 830 and a rod-like portion 831. The stopper portion 830 is formed in a plate shape that is substantially the same shape as the thin film portion 804. One end of the rod-shaped portion 831 is connected to one surface of the stopper portion 830, and the other end is connected to the bottom portion 820.

  The length of the regulating member 83 in the longitudinal direction is configured to be substantially the same as the height of the second hollow portion 803. That is, the regulating member 83 is configured such that the stopper portion 830 is close to the thin film portion 804 in a state where the cap body 82 is attached to the cylindrical portion 801.

  Note that the shape of the regulating member 83 is not limited to the shape shown in FIGS. For example, as shown in FIG. 5A, the restricting member 83 may be formed in a substantially cross-shaped equal cross-sectional shape, or only the stopper portion 830 may be formed in a substantially cross-shaped (not shown). )

  Further, the regulating member 83 may be formed in substantially the same shape as the shape of the second hollow portion 803 as shown in FIG.

  The plug 81 has a circular planar shape, and its diameter is substantially the same as the outer diameter of the external container 7. The plug body 81 has a fitting protrusion 810 that can be fitted to the container main body 80 on the lower surface that is one surface thereof. The fitting protrusion 810 has a shape that protrudes downward concentrically with the outer diameter of the plug 81.

  The plug body 81 is located between the cover cap 9 and the external storage container 7, and is sandwiched between the cover cap 9 and the external storage container 7 by screwing the cover cap 9 into the external storage container 7. Thereby, the component storage container 8 is fixed in the external storage container 7. The inside of the storage container body 80 is sealed by fitting with the plug body 81, and the inside of the external storage container 7 is sealed by screwing the cover cap 9 into the external storage container 7.

  Further, the plug body 81 is provided with a first projecting portion 811 and a second projecting portion 812 on the upper surface. The first protrusion 811 is provided with a first through hole 813 that penetrates from the distal end to the proximal end. The connection tube 4 is connected to the first protrusion 811, and the liquid component derived from the blood reservoir 2 is aseptically stored in the component storage unit 3 via the connection tube 4. The first through-hole 813 functions as a component introduction path through which the liquid component derived from the blood storage container 21 is introduced. The 1st protrusion part 811 and the connection tube 4 are connected by engaging the edge part of the connection tube 4 with the 1st protrusion part 811. FIG.

  Similar to the first protrusion 811, the second protrusion 812 is provided with a second through hole 814 that penetrates from the distal end to the base end. The second through hole 814 functions as a ventilation path through which air enters and exits the component storage container 8.

  A vent tube 5 including a vent filter 6 is further connected to the second projecting portion 812, and is configured to allow air to enter and exit the component storage container 8 through the vent filter 6 and the vent tube 5. The second protrusion 812 and the ventilation tube 5 are connected by engaging the end of the ventilation tube 5 with the second protrusion 812.

  The ventilation filter 6 is a filter having a property of allowing gas to pass but not allowing liquid to pass, and preventing bacteria and the like from passing therethrough. In other words, air is aseptically drawn into and out of the component storage container 8 from the second through hole 814 of the second protrusion 812 to which the ventilation filter 6 is connected.

  The component storage container 8 configured as described above is subjected to high-pressure steam sterilization with the plug body 81 attached to the storage container body 80 and the cap body 82 attached to the cylindrical portion 801. The high-pressure steam sterilization is performed by sterilization with high-temperature and high-pressure saturated steam using a device such as an autoclave, and includes a step of changing the atmospheric pressure in the device up and down. At this time, the inner surface of the peripheral portion 821 of the cap body 82 is welded to the cylindrical portion 801 by heat during high-pressure steam sterilization (so-called blocking adhesion), and the aseptic state in the second hollow portion 803 is maintained.

  Next, a method of using the blood component separation / accommodation apparatus 1 of the first embodiment will be described with reference to FIG. First, as shown in FIG. 1, blood is collected by inserting a blood collection needle 10 into a subject. At this time, the blood collected from the blood collection needle 10 is stored in the blood storage unit 2 via the blood collection tube 11. The blood stored in the blood storage unit 2 is separated at least in part from the liquid component in the blood storage unit 2, and the separated liquid component is transferred to the component storage unit 3 via the connection tube 4. Sent. The sent liquid component is stored in the component storage unit 3 (specifically, stored in the component storage container 8).

  In storing the liquid component in the component storage unit 3, first, the connecting tube 4 and the ventilation tube 5 that connect the blood storage unit 2 and the component storage unit 3 are fused. The component storage container 8 is sealed by fusing the connecting tube 4 and the ventilation tube 5. Thereby, the liquid component accommodated in the component storage container 8 is preserved aseptically.

  When using the stored liquid component, first, the screwing of the cover cap 9 and the external storage container 7 is released, and the component storage container 8 is taken out from the external storage container 7. And the liquid component accommodated in the component storage container 8 is extract | collected.

  The collection of the liquid component stored in the component storage container 8 is performed according to the following procedure. First, the cap body 82 is removed from the cylindrical portion 801 with the component storage container 8 taken out from the external storage container 7. That is, the cap body 82 is detached from the cylindrical portion 801 by operating the opening / closing operation piece 823 to break the thin portion 824. Next, the tip of the puncture tool is inserted into the cylindrical portion 801. Then, the tip of the puncture tool is guided by the inner wall of the cylindrical portion 801 to reach the thin film portion 804, and the thin film portion 804 is broken and punctured. When the puncture device is further inserted, the puncture device is held by the uneven portion 802. In this state, collection of the liquid component in the component storage container 8 is performed. In addition, since the puncture tool is held by the uneven portion 802, the puncture tool is prevented from being excessively pushed.

  According to the component storage container 8 of 1st Embodiment which has the structure mentioned above, there exist the following effects.

  In the component storage container 8, the second hollow portion 803 is sealed by the thin film portion 804, the inner wall of the cylindrical portion 801, and the cap body 82. The component storage container 8 is subjected to high-pressure steam sterilization including a process in which the second hollow portion 803 is sealed and exposed to high-temperature steam and exposed to high pressure and low pressure. As a result of the high-pressure steam sterilization treatment, the thin film portion 804 may be deformed toward the second hollow portion 803 and further damaged.

  Therefore, in the present invention, the regulating member 83 that regulates the deformation of the thin film portion 804 is disposed in the second hollow portion 803. Thereby, when the high pressure steam sterilization process is performed to the component storage container 8, it can prevent that the thin film part 804 deform | transforms into the 2nd hollow part 803 side. Therefore, damage and deformation of the thin film portion 804 due to the high-pressure steam sterilization treatment can be prevented.

  Moreover, the stopper part 830 was provided in the position facing the thin film part 804, and formed in the circular shape of the substantially same shape as the thin film part 804 which is circular shape. Thereby, the deformation of the thin film portion 804 can be more effectively prevented.

  Further, the stopper portion 830 may be formed in a substantially cross shape. By forming the thin film portion 804 in this way, it is only necessary to prevent the minimum deformation in the vertical direction and the horizontal direction which can be considered as a deformation mode of the thin film portion 804, so that the minimum configuration is sufficient. Further, as shown in FIG. 5A, the regulating member 83 may be formed in an equal cross-sectional shape obtained by extending the shape of the stopper portion 830. By forming in this way, the regulating member 83 can be easily formed by extrusion molding.

  Further, the regulating member 83 may be formed in substantially the same shape as the second hollow portion 803. By forming in this way, the second hollow portion 803 is filled with the regulating member 83, so that deformation and breakage of the thin film portion 804 can be prevented. Moreover, it is possible to prevent the cap body 82 from being easily detached from the cylindrical portion 801 by using the uneven portion 802 on the inner wall surface of the cylindrical portion 801 for holding the puncture device.

  Further, the regulating member 83 is formed by being connected to the cap body 82. By forming in this way, if the cap body 82 is removed, the regulating member 83 in the second hollow portion 803 can also be taken out, so that handling becomes easy. Further, by forming the regulating member 83 as the same member as the cap body 82, the number of parts can be reduced.

  Next, a second embodiment of the present invention will be described with reference to FIG. About 2nd Embodiment, a different point from 1st Embodiment mentioned above is mainly demonstrated, and the same point attaches | subjects the same code | symbol and abbreviate | omits description. In particular, the description of the first embodiment is appropriately applied to points that are not described. FIG. 6 is a diagram illustrating a second embodiment.

  As shown in FIG. 6, the component storage container 8 of the second embodiment has a property that gas is allowed to pass through the bottom portion of the cap body 82 but liquid is not allowed to pass, and bacteria and the like are not allowed to pass instead of the regulating member 83. This is different from the first embodiment in that a second ventilation filter 12 having the above is provided.

  According to the liquid container configured as the component container 8 of the second embodiment having the above-described configuration, the following effects can be obtained.

  In the second embodiment, the second ventilation filter 12 is formed on the cap body 82 in place of the regulating member 83 of the first embodiment. The second ventilation filter 12 is a filter having a property of allowing gas to pass but not liquid and not allowing bacteria or the like to pass through, and allows passage of water vapor during high-pressure steam sterilization. Since the pressure in the second hollow portion 803 is equal to the pressure in the second hollow portion 803, the second hollow portion 803 is not in a negative pressure state, so that deformation or damage to the thin film portion 804 is prevented.

  As mentioned above, although this invention was demonstrated based on the preferable embodiment, this invention is not restrict | limited to embodiment mentioned above, It can change suitably.

  For example, in the first embodiment and the second embodiment, the liquid storage container of the present invention is applied to the component storage container 8 in the blood component separation / storage apparatus 1, but the present invention is not limited to this. For example, the present invention may be applied to a liquid container in a physics and chemistry laboratory equipment. That is, there is no particular limitation as long as the container having the configuration of the present invention is used after high-pressure steam sterilization.

  Moreover, in 1st Embodiment, although the cap body 82 and the limitation member 83 were shape | molded integrally, it is not restricted to this aspect. That is, after the cap body 82 and the regulating member 83 are formed separately, they may be connected by bonding or the like.

  Moreover, in 1st Embodiment, although the stopper part 830 of the control member 83 was arrange | positioned close to the thin film part 804 so that it may contact with a deformation | transformation of the thin film part 804, it is not restricted to this. That is, the stopper portion 830 may be disposed so as to contact the thin film portion 804 in a normal state where a force for deforming the thin film portion 804 is not applied. That is, the positional relationship between the thin film portion 804 and the regulating member 83 may be determined in consideration of the deformability of the thin film portion 804.

80 Container body (container body)
804 Thin film part 803 2nd hollow part (hollow part)
801 Cylindrical part (protruding part)
82 Cap body 83 Restriction member 830 Stopper portion 12 Second ventilation filter (ventilation filter)

Claims (6)

A container body in which a liquid is stored;
A thin film portion formed on a part of the container body;
A protruding portion that protrudes from the peripheral edge of the thin film portion toward the outside of the container body, and that has a hollow portion that is open on the tip side;
A cap body that is detachably attached to the distal end side of the protruding portion, and seals the hollow portion;
A liquid container including a regulating member that regulates deformation of the thin film portion toward the hollow portion side in the attached state of the cap body. The regulating member is disposed at a position facing the thin film portion, and has a stopper portion that contacts at least the thin film portion when the thin film portion is deformed,
The liquid container according to claim 1, wherein the stopper portion is formed in substantially the same shape as the thin film portion. The regulating member is disposed at a position facing the thin film portion, and has a stopper portion that contacts at least the thin film portion when the thin film portion is deformed,
The liquid container according to claim 1, wherein the stopper portion is formed in a substantially cross shape.   The liquid container according to claim 1, wherein the regulating member is formed in substantially the same shape as the hollow portion.   The liquid container according to claim 1, wherein the regulating member is connected to the cap body. A container body in which a liquid is stored;
A thin film portion formed on a part of the container body;
A protruding portion that protrudes from the peripheral edge of the thin film portion toward the outside of the container body, and that has a hollow portion that is open on the tip side;
A cap body that is detachably attached to the distal end side of the protruding portion, and seals the hollow portion;
A liquid container including a ventilation filter provided in the cap body.

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