JP2010168370A - Patch sheet for tooth or gum - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a patch sheet for teeth or gums eliminating trouble possessed by a conventional patch sheet, having an excellent feeling of use, sense of incompatibility, adhesiveness to teeth, and operability, wearable in the oral cavity over a long period of time, and effectively applying a medicament. <P>SOLUTION: The patch sheet for the teeth or gums includes a support, and a paste composition having adhesiveness to the teeth or gums. The support has a three-layer structure in which a polyethylene or polypropylene layer (C) having 10-30 μm thickness is interposed between a spunlace nonwoven fabric (A) containing polyethylene terephthalate or polypropylene, and a spunlace nonwoven fabric (B) containing rayon. In the patch sheet for the teeth or gums, an adhesive layer with the paste composition is formed on the spunlace nonwoven fabric (A) containing the polyethylene terephthalate or polypropylene. <P>COPYRIGHT: (C)2010,JPO&INPIT

Description

  The present invention relates to a tooth or gum sticking sheet that is used by being stuck to a tooth or gum in the oral cavity.

  Conventionally, various products for the purpose of preventing or treating oral diseases and removing dirt and odors in the oral cavity have been proposed and marketed. Major oral diseases include periodontal diseases such as caries and gingivitis, oral mucosal diseases such as stomatitis, hypersensitivity due to exposure of dentin, and the sources of dirt and odor include food residues, Examples include tobacco spider, dental plaque, tartar, tongue coating, bacteria, and specific drug substances.

  And as a product for preventing or treating these oral diseases or removing causative substances, oral hygiene products such as dentifrice, mouthwash, oral spray, toothbrush, interdental cleaning tool, toothpaste gum, dental caries prevention tablet, Foods such as bad breath prevention capsules are commercially available.

These oral preparations are often chemically or biologically decomposed, sterilized, or removed causative agents of diseases, dirt, and odors, suppressed inflammation and bleeding, and promoted tissue resilience in the body. As components, various medicinal components, or components such as surfactants, solvents, deodorants and fragrances are included. As such components, for example, for teeth, bleaching with peroxides, chelating agents, removal of colored stains such as tea astringents and tobacco crab with polyethylene glycol, or acid resistance strengthening of teeth using fluorine compounds, Ingredients for calcification are listed. For gums, periodontal tissue activation and pathological tolerance enhancement by vitamins and derivatives thereof, hemostasis by antiplasmin agents, redness by anti-inflammatory agents, tumor suppression Ingredients for the purpose of removing periodontal disease bacteria with bactericides and the like.
In addition, these components are often dramatically improved by applying them for a long time to dirt or tissue in the target mouth.

  However, conventional oral preparations are often used in such a way that they remain in the oral cavity for only a very short time, such as brushing teeth, washing mouth, and eating and drinking, and are often diluted with saliva during use. In order to enhance biological effectiveness, a dosage form and method of use that remain in the oral cavity for a long time without undergoing dilution of saliva and exhibit an effect have been desired. As a means to increase the retention of the drug, it can be used easily as a home care preparation, and as a product for forcibly holding the drug for a long time without being diluted with saliva, it can be applied to a support such as strips. A patch sheet provided with a drug layer is an excellent dosage form.

  However, since the conventional sticking sheet has a simple rectangle, circle, ellipse or similar shape, when sticking to a target site, it often sticks to some non-target areas. Furthermore, since the shape of the teeth and gums is often uneven, during long-time application, the formulation is gradually eluted or released from the gap at the boundary between the application target site and the surrounding tissue and often spreads to the periphery. . For example, even if it is applied to teeth, the product flows out to the adjacent gingiva and mucous membrane, causing unpleasant discomfort, or a large amount of saliva induced by the dissolution of the dissolved product, resulting in a marked decrease in adhesiveness of the adhesive sheet. As a result, it is often difficult to wear for a long time. For this reason, the shape which does not feel strange at the time of wear has been desired. In order to achieve these objects, the following various proposals have been made regarding the shape, material, and the like.

  Regarding the shape, JP-T-2004-538085 (Patent Document 1), JP-T 2002-503990 (Patent Document 2), JP-T 2002-506434 (Patent Document 3), JP-T 2002-539502 ( Patent Document 4) proposes a rounded rectangular or substantially rectangular sheet shape. However, since these shapes are not intended to be folded back on the back surface (tongue surface) of the teeth or gums, there is no contrivance for folding back and it is difficult to fold back, and satisfactory effects cannot be obtained.

  Japanese Patent Application Publication No. 2002-538887 (Patent Document 5) proposes a shape having a folding line such as a substantially trapezoidal shape that does not cover canine teeth, a substantially rectangular shape with steps, a substantially rectangular shape with notches, and a rectangular shape with slits. Further, the applicant has disclosed a tooth-shaped sheet with a folding line in Japanese Patent Laid-Open No. 2001-322928 (Patent Document 6), and a tooth front surface (lip) in a folded shape in Japanese Patent Laid-Open No. 2001-335470 (Patent Document 7). Surface) The application part was proposed with a tooth-shaped sheet and a cut-in shape larger than the tooth back part (lingual surface) application part. However, these are difficult to fold because the width of the fold line is narrow, and in Patent Document 7, the shape having a notch on the back surface (tongue surface) is easier to fold and stick than the one having only the fold line. It has been found that there is a problem that it is difficult to say that the adhesiveness on the back surface is still sufficient because the sheets folded on the back surface are overlapped with each other simply by cutting.

  On the other hand, regarding the material, Japanese Patent Publication No. 2004-538085 (Patent Document 1) discloses a support body in which a saliva-absorbing layer can be provided as a single layer or multiple layers containing a plastically deformable material. No. (Patent Document 2), Japanese Translation of PCT International Publication No. 2002-506434 (Patent Reference 3) and Japanese Patent Publication No. 2002-538887 (Patent Reference 5) are substantially single-layered or multi-layered material pieces. A permeable support has been proposed.

The applicants disclosed in JP-A-2001-322928 (Patent Document 6) and JP-A-2001-335470 (Patent Document 7) a water-impermeable film of polyethylene, polypropylene, and polyethylene terephthalate as a support. Alternatively, a three-layer sheet composed of a polyethylene terephthalate non-woven fabric / rayon non-woven fabric with a water-insoluble polyethylene film interposed in the middle is proposed (PET / PE / rayon tri-layer support). ) And a thickness of 0.5 mm.
However, it has been found that a plastic material in the support or a simple water-impermeable material has a poor usability due to a strong sense of discomfort in the oral cavity at the time of application. Although the above PET / PE / rayon three-layer support is a structure that takes into account the problem, there are many improvements such as being difficult to fold back to the back of the tooth because the support is hard and peeling off from the back after application. there were.

  In addition, as for the release liner of the sheet, Japanese Patent Application Publication No. 2002-503990 (Patent Document 2), Japanese Patent Application Publication No. 2002-506434 (Patent Document 3) and Japanese Patent Application Publication No. 2002-538887 (Patent Document 5) are released. As the liner, a hard sheet material to which a non-adhesive material such as polyethylene, paper, polyester, or silicon is preferably applied has been proposed. Japanese Patent Application Publication No. 2004-536949 (Patent Document 8) describes that a dynamic friction coefficient of a release liner is at least about 0.3 in an article including an adhesive layer disposed between a base material and a liner. ing. However, even with a liner coated with a non-adhesive substance, when the dynamic friction coefficient is 0.3 or more, the liner may not be peeled depending on the composition of the layer disposed between the substrate and the liner.

Special table 2004-538085 gazette JP 2002-503990 Gazette Special table 2002-506434 gazette Special Table 2002-539502 Special table 2002-538887 gazette JP 2001-322928 A JP 2001-335470 A JP-T-2004-536949 Publication

  The present invention has been made in view of the above circumstances, solves the problems of conventional adhesive sheets, is superior in feeling of use, discomfort, adhesiveness to teeth, and operability, and can be worn in the oral cavity for a long time. An object of the present invention is to provide a patch sheet for teeth or gums to which a drug can be effectively applied.

  As a result of intensive studies to achieve the above object, the present inventors have obtained a support and a paste sheet for tooth or gum comprising a support and a plaster composition having adhesiveness to the tooth or gum. Three layers in which a polyethylene or polypropylene layer (C) having a thickness of 10 to 30 μm is interposed between a spunlace nonwoven fabric (A) containing polyethylene terephthalate or polypropylene and a spunlace nonwoven fabric (B) containing rayon By forming a pressure-sensitive adhesive layer with a plaster composition on a spunlace nonwoven fabric (A) having a structure and containing polyethylene terephthalate or polypropylene, it is possible to eliminate the disadvantages of conventional tooth paste sheets, and to obtain teeth or gums Can be satisfactorily and easily applied to the target site without peeling, especially on the back side (lingual surface) of the teeth immediately after application and during application Wear resistance is exhibited, and can be worn long without discomfort, effectively it found that can be applied to drug application site, the present invention has been accomplished.

The adhesive sheet of the present invention has an intermediate layer in which polyethylene or polypropylene, particularly low-density polyethylene is interposed between a spunlace nonwoven fabric (A) containing polyethylene terephthalate or polypropylene and a spunlace nonwoven fabric (B) containing rayon. Compared to conventional multi-layer support, for example, a support containing a plastic material with a water-impermeable film or the like interposed in between, there is less discomfort in the oral cavity at the time of application to a tooth or gum, and the feeling of use It is easy to fold the sheet so that the support is soft and can be applied to the back of teeth, and is difficult to peel off from the application surface after application. Excellent in operability and adhesiveness to teeth or gums and can be worn for a long time. It is.
Furthermore, in the present invention, polyethylene or polypropylene which is an intermediate layer of the three-layer support acts as a water-impermeable barrier layer, and the adhesive layer is excessively adsorbed on the support or penetrates through the nonwoven fabric or the like. It is possible to prevent elution into the oral cavity, or conversely, saliva permeates through the nonwoven fabric and enters the pressure-sensitive adhesive layer.

  In the present invention, a support having a three-layer structure of a spunlace nonwoven fabric (A) containing hydrophobic polyethylene terephthalate or polypropylene, a polyethylene or polypropylene layer (C), and a spunlace nonwoven fabric (B) containing a hydrophilic rayon. By applying the pressure-sensitive adhesive layer on the hydrophobic spunlace nonwoven fabric (A), the liquid component in the pressure-sensitive adhesive layer can be prevented from adsorbing to the nonwoven fabric that is the contact surface over time, and therefore, There is almost no peeling from the application surface of the tooth after sticking, and there is almost no peeling from the application surface of the tooth after sticking. On the other hand, since the saliva-absorbing surface is a spunlace nonwoven fabric (B) containing a hydrophilic rayon, the saliva does not overflow in the oral cavity at the time of application, and the feeling of use and adhesiveness are hardly lowered, and an uncomfortable feeling may occur. Absent. Furthermore, since both the nonwoven fabrics (A) and (B) are spunlace nonwoven fabrics, they have good tactile sensation and high affinity with saliva and pressure-sensitive adhesive layers. The adhesiveness and operability can be obtained.

  The adhesive sheet for teeth or gums of the present invention further has a shape capable of covering both the lip surface and the tongue surface of the teeth or gums via the folded portion, and the line width of the folded portion is 0.5 to The effect of the invention is more conspicuous by having a notch part with a maximum width of 2 to 15 mm from the bottom part toward the tooth direction on the bottom side of the tongue surface sticking part that covers the tongue face of the tooth or gum. To be demonstrated.

  Further, in the sheet of the present invention, the pressure-sensitive adhesive layer formed on the spunlace nonwoven fabric (A) containing polyethylene terephthalate or polypropylene is coated with a release liner, and the release liner is polyethylene terephthalate, polyethylene, polypropylene. The adhesive layer can be effectively protected when the coefficient of dynamic friction is 0.05 to 0.24, and the release liner can be easily peeled off from the adhesive layer during use. .

  The plaster composition forming the adhesive layer is preferably an adhesive oral composition containing an alginate and hydroxyethyl cellulose, and may further contain condensed phosphoric acid and / or a salt thereof as a whitening component. preferable. By containing condensed phosphoric acid and / or a salt thereof, an excellent stain removal effect is exhibited, and teeth or gums can be effectively whitened.

In addition, the sheet of the present invention has a release liner and a support bonded thereto via an adhesive layer, and the outer peripheral edge of the support is embossed with the adhesive layer toward the release liner. It is preferable that the outer peripheral edge portion of the support is more embossed so that the thickness of the pressure-sensitive adhesive layer is 0.05 to 0.5 mm. Further, when the support has a folded portion, the folded portion is preferably embossed with the adhesive layer toward the release liner, and the folded portion of the support has a thickness of the adhesive layer. It is preferable that the die is pressed so as to be 0.5 mm or less. The release liner is desirably larger than the support.
Furthermore, the sheet of the present invention can be such that the support and the pressure-sensitive adhesive layer are cut from the support side toward the release liner, and the release liner is half-cut (a part of its thickness is cut), In this case, the notch formed at the bottom of the tongue surface sticking part covering the tongue surface of the teeth or gums from the bottom toward the tooth is V-shaped, and the V-shaped tip has a radius of curvature of 0.5 mm. The semi-circular or trapezoidal shape is preferable.
By performing the embossing and half-cut processes in this way, it is possible to effectively suppress the paste composition from protruding from the outer peripheral edge of the support during storage or transportation of the adhesive sheet.

Therefore, the present invention provides the following sticking sheet for teeth or gums.
Claim 1:
A patch sheet for teeth or gums comprising a support and a plaster composition having adhesiveness to teeth or gums, wherein the support comprises a spunlace nonwoven fabric (A) containing polyethylene terephthalate or polypropylene; A spunlace nonwoven fabric (A) having a three-layer structure in which a polyethylene or polypropylene layer (C) having a thickness of 10 to 30 μm is interposed between the spunlace nonwoven fabric (B) containing rayon and containing the polyethylene terephthalate or polypropylene An adhesive sheet for teeth or gums, wherein an adhesive layer made of a plaster composition is formed thereon.
Claim 2:
The tooth or gum sticking sheet has a shape capable of covering both the lip surface and the tongue surface of the tooth or gum via the folded portion, and the line width of the folded portion is 0.5 to 5 mm. The sticking sheet for teeth or gums according to claim 1 characterized by the above-mentioned.
Claim 3:
3. A tooth or gum for a tooth or gum according to claim 2, wherein a notch having a maximum width of 2 to 15 mm is formed from the base toward the tooth toward the bottom of the tongue surface sticking part covering the tongue surface of the tooth or gum. Affixed sheet.
Claim 4:
The adhesive sheet formed on the spunlace nonwoven fabric (A) containing polyethylene terephthalate or polypropylene is coated with a release liner, The adhesive sheet for teeth or gums according to claim 1, 2, or 3.
Claim 5:
The adhesive sheet for teeth or gums according to claim 4, wherein the release liner is made of a material selected from polyethylene terephthalate, polyethylene, and polypropylene, and has a dynamic friction coefficient of 0.05 to 0.24.
Claim 6:
The tooth or gum sticking sheet according to any one of claims 1 to 5, wherein the plaster composition forming the adhesive layer is an adhesive oral composition containing an alginate and hydroxyethyl cellulose.
Claim 7:
The adhesive sheet for teeth or gums according to claim 6, wherein the plaster composition further contains condensed phosphoric acid and / or a salt thereof.
Claim 8:
5. A release liner and a support bonded thereto via a pressure-sensitive adhesive layer, and the outer peripheral edge of the support is pressed together with the pressure-sensitive adhesive layer toward the release liner. The tooth or gum sticking sheet according to any one of 7 above.
Claim 9:
The tooth or gum sticking sheet according to claim 8, wherein the outer peripheral edge of the support is embossed so that the thickness of the pressure-sensitive adhesive layer is 0.05 to 0.5 mm.
Claim 10:
Furthermore, when the said support body has a folding | returning part, this folding | returning part was embossed with the adhesive layer toward the peeling liner, The sticking sheet for teeth or gums of Claim 8 or 9.
Claim 11:
The tooth or gum sticking sheet according to claim 10, wherein the folded portion of the support is embossed so that the thickness of the pressure-sensitive adhesive layer is 0.5 mm or less.
Claim 12:
The adhesive sheet for teeth or gums according to any one of claims 4 to 11, wherein the release liner is larger than the support.
Claim 13:
The adhesive sheet for teeth or gums according to any one of claims 4 to 12, wherein the support and the pressure-sensitive adhesive layer are cut from the support side toward the release liner, and the release liner is half-cut.
Claim 14:
A semicircular shape in which the cut portion formed from the base toward the tooth direction is V-shaped and the tip of the V-shaped is a radius of curvature of 0.5 mm or more at the bottom of the tongue surface sticking portion covering the tongue surface of the tooth or gum Or it is a trapezoid shape, The sticking sheet for teeth or gums of Claim 13.

According to the present invention, the problems of the conventional tooth sticking sheet are eliminated, the feeling of use of the sheet sticking to the teeth or gums is excellent, there is little discomfort due to saliva staying in the oral cavity, immediately after sticking and during sticking High adhesion to the back side (tongue surface) of the teeth. Further, when the pressure-sensitive adhesive layer is protected with a release liner, the release liner used for protection can be easily peeled off from the pressure-sensitive adhesive layer during use. Furthermore, by blending a drug or the like with the plaster composition forming the pressure-sensitive adhesive layer, the effects derived from the blended components are effectively exhibited, and if condensed phosphoric acid and / or a salt thereof is blended as a whitening component, the higher Stain removal effect is exhibited, and teeth or gums can be effectively whitened. Further, in the present invention, the outer peripheral edge of the support of the sheet having a release liner and a support bonded thereto via an adhesive layer, and further, when the support has a folded portion, The folded portion is embossed together with the adhesive layer toward the release liner, and further, the outer peripheral edge that has been embossed is cut with a half cutter to prepare the support sheet for storage or transportation. It is possible to effectively suppress the plaster composition from protruding from the outer peripheral edge portion, and the operability at the time of application is also improved.

It is a schematic sectional drawing which shows one Example of the sticking sheet of this invention. It is a schematic sectional drawing which shows one Example of the support body in connection with the sticking sheet of this invention. It is a top view which shows one Example of the sticking sheet | seat of this invention (For front teeth 6-7 teeth, a fold line and a notch | no cut). It is a top view which shows the sticking sheet of one Example (Example 1) of the sticking sheet of this invention (For front teeth 6-7 teeth, there is no fold line and a notch). It is a top view which shows one Example of the sticking sheet | seat of this invention (for 1 tooth | gear, a fold line and a notch). It is a top view which shows the sticking sheet of one Example (Example 2) of the sticking sheet of this invention (folding line | wire width 3mm, there is no notch). It is a top view which shows one Example of the sticking sheet of this invention (folding line | wire width 0.8mm, there is no notch). It is a top view which shows one Example of the sticking sheet of this invention (folding line | wire width 3mm, 1mm, there is no notch). It is a top view which shows one Example of the sticking sheet of this invention (folding line | wire width 3mm, 1mm, there is no notch). It is a top view which shows one Example of the sticking sheet of this invention (folding line | wire width 3mm, there is no notch). It is a top view which shows one Example of the sticking sheet of this invention (folding line | wire width 3mm, there is no notch). It is a top view which shows one Example of the sticking sheet of this invention (folding line | wire width 3mm, there is no notch). It is a top view which shows one Example of the sticking sheet of this invention (folding line | wire width 3mm, there is no notch). It is a top view which shows one Example of the sticking sheet of this invention (folding line | wire width 3mm, there is no notch). It is a top view which shows one Example of the sticking sheet of this invention (folding line | wire width 3mm, notch width 3mm). It is a top view of the sticking sheet of one Example (Example 3, Examples 22-32) of the sticking sheet of the present invention (folding line width 3 mm, cut width 3 mm). It is a top view which shows one Example of the sticking sheet of this invention (folding line | wire width 3mm, notch width 3mm). It is a top view of the sticking sheet of one Example (Example 5) of the sticking sheet of the present invention (folding line width 3 mm, cut width 2 mm). It is a top view of the sticking sheet of one Example (Example 19) of the sticking sheet of this invention (folding line | wire width 3mm, cutting width 10mm). It is a top view of the sticking sheet of one Example (Example 20, Example 35) of the present invention (folding line width 3 mm, U-shaped cut width 3 mm). It is a top view of the sticking sheet of one Example (Example 37) of the sticking sheet of this invention (Folding line width 3mm, three straight cuts, and a cut width 3mm). It is a top view which shows one Example of the sticking sheet of this invention (folding line | wire width 3mm, notch width 3mm). It is a top view which shows one Example of the sticking sheet of this invention (folding line | wire width 3mm, notch width 3mm). It is a top view which shows one Example of the sticking sheet of this invention (Folding line | wire width 1mm, cut width 3mm). It is a top view of the sticking sheet of one Example (Example 36) of the sticking sheet of this invention (folding line width 3mm, V-shaped cut | notch width 3mm). It is a top view which shows one Example of the sticking sheet of this invention (Folding line | wire width 3mm, V-shaped cut | notch width 3mm). It is a top view which shows one Example of the sticking sheet of this invention (Folding line | wire width 3mm, V-shaped cut | notch width 3mm). It is a top view which shows one Example of the sticking sheet of this invention (Folding line | wire width 3mm, V-shaped cut | notch width 3mm). It is a top view which shows one Example of the sticking sheet of this invention (Folding line | wire width 3mm, V-shaped cut | notch width 3mm). It is a top view of the sticking sheet of one Example (Example 33) of the sticking sheet of this invention (folding line | wire width 3mm, V-shaped cut | notch width 3mm). It is a top view of the sticking sheet of one Example (Examples 40-47) of the sticking sheet of the present invention (folding line width 3mm, V-shaped cut width 3mm). It is a partial schematic sectional drawing in alignment with the broken-line part AA of the sticking sheet | seat of FIG. It is a top view of the sticking sheet of one Example (Example 48) of the sticking sheet of this invention. ). It is a partial schematic sectional view which shows the state which embossed the sticking sheet of this invention using the embossing roll. It is a partial schematic sectional view which shows the state which cut | disconnected the sticking sheet of this invention with the blade of the half cutter. It is a partial schematic sectional drawing which shows the state which cut | disconnected the sticking sheet of this invention with the half cut roll. It is a top view of the tooth sticking sheet of one Example (Examples 6-9) of the present invention (shape is FIG. 6, folding line width 0.8mm, cut width 3mm). It is a top view of the sticking sheet of one Example (Example 4) of the sticking sheet of this invention (a shape is FIG. 6, folding line width 4mm, cutting width 3mm). It is a top view of the sticking sheet of one Example (Examples 10-14) of the sticking sheet of this invention (a shape is FIG. 6, folding line width 3mm, cutting width 4mm). It is a top view of the sticking sheet of one Example (Example 15) of the sticking sheet of this invention (a shape is FIG. 6, folding line width 5mm, cutting width 3mm). It is a top view of the sticking sheet of one Example (Example 16) of the sticking sheet of this invention (a shape is FIG. 6, folding line width 0.5mm, cutting width 3mm). It is a top view of the sticking sheet | seat of one Example (Example 21, Example 34) of the sticking sheet | seat of this invention (a shape is FIG. 6, folding line | wire width 0.8mm, and a straight notch). It is a top view of the sticking sheet of one Example (for the upper jaw of Example 38) of the sticking sheet of the present invention (the shape is FIG. 6, no fold line, V-shaped cut width of 3 mm). It is a top view of the sticking sheet of one Example of the sticking sheet of the present invention (for the upper jaw of Example 39) (the shape is FIG. 6, the folding line is 3 mm, the semicircular cut width is 6 mm, and the cut depth is the width of the sheet) 1/2 of the length from the outer peripheral edge to the folding line (length in the vertical direction). It is a top view of the sticking sheet of one Example (Example 17) of the sticking sheet of this invention (a shape is FIG. 6, folding line width 3mm, cutting width 5mm). It is a top view of the sticking sheet of one Example (Example 18) of the sticking sheet of this invention (a shape is FIG. 6, folding line width 3mm, cutting width 1mm).

Hereinafter, the present invention will be described in more detail.
The tooth or gum sticking sheet of the present invention is formed into a sheet for the purpose of sticking to one or more teeth or gums, and an adhesive layer containing a drug or the like is preferably formed on one surface thereof. A support and a plaster composition having adhesiveness to teeth or gums, the support comprising a spunlace nonwoven fabric (A) containing polyethylene terephthalate or polypropylene, and a spunlace nonwoven fabric (B) containing rayon; Having a three-layer structure in which a polyethylene or polypropylene layer (C) having a thickness of 10 to 30 μm is interposed therebetween, and an adhesive with a plaster composition on the spunlace nonwoven fabric (A) containing the polyethylene terephthalate or polypropylene A layer is formed.

The adhesive sheet can cover an adhesive layer formed on a spunlace nonwoven fabric (A) containing polyethylene terephthalate or polypropylene with a release liner made of a material selected from polyethylene terephthalate, polyethylene, and polypropylene.
In addition, a sticking sheet | seat should be a thing which does not have easy extensibility at the time of sticking.

  FIG. 1 is a schematic cross-sectional view of a sticking sheet for teeth or gums of the present invention. In the sticking sheet 1 of FIG. 1, 2 is a support and 3 is an adhesive layer. Reference numeral 4 denotes a release liner, which can cover the pressure-sensitive adhesive layer with a release liner. FIG. 2 is a schematic sectional view of a support according to the present invention. In the support 2, 5 is a spunlace nonwoven fabric (A) containing polyethylene terephthalate or polypropylene, 6 is a polyethylene or polypropylene layer (C), and 7 is rayon. The spunlace nonwoven fabric (B) includes a polyethylene or polypropylene layer (C) 6 between the nonwoven fabric (A) 5 and the nonwoven fabric (B) 7 and has a three-layer structure. In this invention, the adhesive layer 3 by the plaster composition is formed on the nonwoven fabric (A) 5 of the support 2 in FIG. 2, and is interposed between the nonwoven fabric (A) and the nonwoven fabric (B) 5. The polyethylene or polypropylene layer (C) 6 becomes a barrier layer, and the non-woven fabric (B) 7 becomes a surface in contact with saliva.

  The support of the present invention (hereinafter abbreviated as three-layer support) comprises a spunlace nonwoven fabric containing hydrophobic polyethylene terephthalate or polypropylene and a spunlace nonwoven fabric containing hydrophilic rayon with a polyethylene or polypropylene layer interposed. 3 layers support bonded together, polyethylene or polypropylene acts as a water-impermeable barrier layer, so that the pressure-sensitive adhesive layer is excessively adsorbed to the support or penetrates through the nonwoven fabric etc. It is possible to prevent the saliva from permeating through the nonwoven fabric or the like and entering the pressure-sensitive adhesive layer.

  As a production method of the three-layer support, the nonwoven fabric (A) and the nonwoven fabric (B) may be bonded to a film-like polyethylene or polypropylene with a known adhesive, or two kinds of heat-dissolved polyethylene or polypropylene are used. The non-woven fabrics ((A) and (B)) may be bonded and molded by pressure fusion, but the non-woven fabrics (A) and (B) are particularly bonded with heat-dissolved polyethylene or polypropylene. Further, it is more preferable to perform pressure fusion because the non-woven fabric (A) and the non-woven fabric (B) can be firmly adhered. Here, the pressure welding condition is a nip pressure of 0.2 to 10 kg.

  The nonwoven fabrics (A) and (B) constituting the three-layer support used in the present invention are manufactured by the spunlace method. There are various methods for producing non-woven fabrics, including a spunlace method, a spunbond method, a needle punch method, a melt flow method, and the like. Among these, a product produced by a spunlace method is used. For example, when a spunbonded nonwoven fabric is used on the adhesive coated surface, the surface becomes smooth because the nonwoven fabric is crimped together, and the adhesive layer cannot be sufficiently retained by embossing the surface alone. It is inferior in adhesiveness to a part, especially the tongue surface. Other manufacturing methods include needle punching, but the nonwoven fabric produced by this method may lose fiber from the nonwoven fabric during or after application. On the other hand, spunlace nonwoven fabrics manufactured by the spunlace method have moderate roughness on the surface, and fibers do not come out. Excellent tack that cannot be obtained by using nonwoven fabrics obtained by these other methods. Can be effectively used for the three-layer support of the present invention.

  The surface on which the pressure-sensitive adhesive layer of the three-layer support is applied (hereinafter abbreviated as the pressure-sensitive adhesive coating surface) is a spunlace nonwoven fabric (A) containing hydrophobic polyethylene terephthalate or polypropylene, and is particularly adhesive to teeth. From the viewpoint of operability, a spunlace nonwoven fabric preferably containing a polyethylene terephthalate fiber is coated with an adhesive layer on one side. In addition, when the pressure-sensitive adhesive coated surface is a water-absorbing nonwoven fabric such as a spunlace nonwoven fabric containing rayon, the liquid component in the pressure-sensitive adhesive layer is absorbed into the nonwoven fabric over time, and the pressure-sensitive adhesive layer is applied to the teeth or gums. Adhesiveness will decrease.

  The content of polyethylene terephthalate or polypropylene in the spunlace nonwoven fabric (A) is preferably 50 to 100% (mass%, the same shall apply hereinafter), and particularly preferably 80 to 100%. When the content is less than 50%, the moisture in the pressure-sensitive adhesive layer is absorbed by the support and the adhesiveness to the teeth may be lowered.

  As long as the spunlace nonwoven fabric (A) contains polyethylene terephthalate or polypropylene, it may contain other hydrophobic or hydrophilic fibers as long as the effects of the present invention are not hindered. Fibers can be included. The content is preferably 0 to 50%, particularly preferably 0 to 20%, and the lower limit when it is contained is 1% or more.

As such spunlace nonwoven fabric (A), commercially available products can be used. Specifically, polyethylene terephthalate nonwoven fabric (manufactured by Shinwa Co., Ltd., 7840A, basis weight 40 g / m ² ), polyethylene terephthalate / rayon = 8/2 (Shinwa) Manufactured by Co., Ltd., basis weight 40 g / m ² ), polyethylene terephthalate / rayon = 5/5 (manufactured by Shinwa Co., Ltd., basis weight 70 g / m ² ), polyethylene terephthalate / rayon = 35/65 (manufactured by Shinwa Co., Ltd., basis weight) 40 g / m ² ).

The basis weight (basis weight) of the spunlace nonwoven fabric (A) containing polyethylene terephthalate or polypropylene is preferably 30 to 40 g / m ² . When the basis weight is less than 30 g / m ² , the adhesiveness to the teeth may be lowered, and when the basis weight is more than 40 g / m ² , the support becomes hard and thick, and the feeling of use during the application, The adhesiveness to the teeth and operability may be reduced.

  The surface opposite to the adhesive-coated surface of the three-layer support used in the present invention (hereinafter referred to as saliva absorbing surface) is a spunlace nonwoven fabric (B) containing hydrophilic rayon, and the saliva absorbing surface is hydrophilic. It is possible to reduce saliva overflow in the oral cavity, and to prevent the feeling of use, discomfort, and decrease in adhesiveness. When a hydrophobic non-woven fabric such as polyethylene terephthalate or polypropylene is used for the saliva absorbing surface, saliva overflows in the oral cavity during application, which not only deteriorates the feeling of use but also reduces the adhesiveness to the teeth.

  The content of rayon in the spun lace nonwoven fabric containing rayon which is a saliva absorbing surface is preferably 25 to 100%, particularly 50 to 100%, and particularly preferably 70 to 100%. When the content is less than 25%, the saliva generated during the sticking cannot be sufficiently absorbed, and the feeling of use and adhesiveness to the teeth may be lowered.

  The spunlace nonwoven fabric (B) may contain other hydrophobic or hydrophilic fibers other than rayon within a range not impeding the effects of the present invention, for example, other fibers such as polyethylene terephthalate and polypropylene. Can do. The content is preferably 0 to 50%, particularly preferably 0 to 20%, and the lower limit when it is contained is 1% or more.

The basis weight of the spunlace nonwoven fabric (B) containing rayon which is a saliva absorbing surface is preferably 40 to 60 g / m ² . If the basis weight is less than 40 g / m ² , the saliva produced during application cannot be sufficiently absorbed, and the feeling of use and adhesiveness to the teeth may be inferior. If the basis weight exceeds 60 g / m ^2, 3 Since the layer support becomes hard, the feeling of use, operability, and adhesiveness to teeth may be reduced.

As such spunlace nonwoven fabric (A), commercially available products can be used. Specifically, rayon nonwoven fabric (Shinwa Co., Ltd., 7140A, basis weight 40 g / m ² ), rayon / polypropylene = 7/3 (Shinwa Corp.) ), 7140-6, 40 g / m ² per unit area), rayon / polypropylene = 5/5 (manufactured by Shinwa Co., Ltd., 40 g / m ² per unit area), rayon / polyethylene terephthalate / polypropylene = 25/60/15 (Nippon Vilene) Ltd., EW-550, include basis weight 55 g / m ²⁾ and the like.

The material of the barrier layer of the three-layer support is polyethylene or polypropylene, and is preferably polyethylene, particularly low-density polyethylene, from the viewpoints of feeling during use, adhesiveness to teeth, and operability. Here, the low density is preferably a density of 910 to 930 kg / m ³ . Specific examples of the low density polyethylene include Novatec LD manufactured by Nippon Polyethylene Co., Ltd.

  The thickness of the barrier layer is 10 to 30 μm, and particularly preferably 15 to 25 μm. When the thickness is less than 10 μm, a large number of pinholes are generated, and the adhesive layer permeates through the nonwoven fabric and the adhesive layer elutes in the oral cavity, or conversely, saliva permeates through the nonwoven fabric and enters the adhesive layer. As a result, the feeling of use during application and the adhesiveness to the teeth decrease. On the other hand, when the thickness exceeds 30 μm, the three-layer support is too hard, and the usability, operability, and adhesiveness to teeth are reduced.

In the three-layer support used in the present invention, the thickness of the support is not particularly limited as long as the pressure-sensitive adhesive layer can be firmly fixed to the application site and the intrusion of saliva and the elution of the pressure-sensitive adhesive layer can be prevented. It is preferable that the thickness of the support and the pressure-sensitive adhesive layer is 0.2 to 5 mm, particularly 0.8 to 2.2 mm. If the thickness is less than 0.2 mm, the adhesiveness to the teeth may be reduced, and if it exceeds 5 mm, the adhesiveness becomes too thick, the operability and the feeling of use are inferior, and the adhesiveness to the teeth may also be reduced.
The thickness of the support is 0.1 to 2.0 mm, preferably 0.2 to 0.6 mm.

The shape of the adhesive sheet of the present invention is not particularly limited as long as it is a shape that can be easily applied to teeth, and can be formed into a shape corresponding to the application range, that is, the number and shape of the teeth or gums to be applied. Can be formed into a shape having a tooth neck portion line, or the outer peripheral surface can be formed into a curved shape or a curved shape.
3 to 5 are specific examples of the adhesive sheet. 3 and 5, FIGS. 3 and 4 are for front teeth 6 to 7, and FIG. 5 is for one tooth. In the case of the front teeth 6 to 7 teeth, the sheet outer periphery is formed in a state in which the outer periphery of the sheet is wave-like or semicircular or semi-elliptical, and the adhesive sheet having the shape shown in FIG. preferable.

  Further, the size of the tooth sticking sheet may be a size suitable for the sticking site depending on the product purpose. For example, in the shape of FIG. 3, the upper jaw and the lower jaw are different in size, so that for the upper jaw, the maximum horizontal width is 50 to 80 mm, the maximum vertical width is 15 to 35 mm, especially the maximum horizontal width is 55 to 70 mm, and the maximum vertical width is 20 to 30 mm. Is preferred. For the lower jaw, a maximum width of 40 to 70 mm, a maximum length of 15 to 35 mm, particularly a maximum width of 45 to 60 mm and a maximum length of 20 to 30 mm are preferable.

  The patch sheet can have a shape capable of covering both the lip surface and the tongue surface of the tooth or gum via the folded portion. By folding and sticking the sheet at the folded part, both sides of the teeth or gums (lip surface and lingual surface) can be covered simultaneously with one sheet. In this case, sufficient to cover both sides in this way It is preferably formed in a shape having a vertical dimension. In addition, the maximum lateral dimension of the lip surface application portion of the sheet with the folded portion as the boundary (in the present invention, “lateral” refers to the tooth arrangement direction and this is described as “width”) is applied to the tongue surface. It can be formed such that it is larger than the minimum lateral dimension (minimum width) of the part, or the area of the lip surface sticking part is larger than the area of the tongue face sticking part.

Moreover, although the sticking sheet is used by being folded at the folded portion as described above, in this case, the adhesion effect can be further exerted by folding the sheet at a predetermined position that matches the sheet shape. Therefore, it is more desirable that the bent portion is clear. Specifically, in order to clarify the folded portion, a folded line such as a solid line, a dotted line, or a chain line is drawn on the folded portion, a crease is provided, a cut line such as a dotted line, a chain line is provided, or both ends of the folded portion The folding position is clarified and the holding and fixing force is improved by means such as providing cuts, dents, or drawing a linear display portion for displaying the folding position at both ends.
In addition, it is preferable to provide a folding | returning part in the position on the lingual side slightly from the center part of the longitudinal (height) direction of a patch or this center part.

As the patch sheet, a sheet in which a folded portion and a notch are formed in the tooth back surface (lingual surface) paste portion is suitable. The folded portion of the tooth sticking sheet is provided in order to make it easy to fold the sticking sheet to the back surface at the tooth cutting edge, or to make the position of the tooth cutting edge easy to understand when sticking to the tooth. For example, the folded portion can be a folded portion having a certain width in a straight line shape or along a dental arch in the dentition direction of the adhesive sheet, and the width is 0.5 to 5 mm, in particular 0.8-4 mm is preferable. If it is less than 0.5 mm, it is too thin and difficult to fold, and the operability at the time of application and the adhesiveness to the back side of the tooth may decrease. If it exceeds 5 mm, it is too wide and the adhesiveness to the back side of the tooth and the feeling of use May decrease.
Further, the folded portion can be formed in the tooth alignment direction, and may be formed by one, but may be formed in plural, and when formed in plural, the portion between the folded portions may be interrupted, and the length and width may be May be different. In addition, the length of the folded portion is preferably 35 to 80 mm, particularly 40 to 55 mm when one is formed, and is preferably 10 to 35 mm, particularly 15 to 30 mm when forming a plurality of folded portions. is there.

6 to 14 show specific examples of various patch sheets having different sheet shapes and widths of folding lines in the patch sheet of the present invention, wherein 12 is a lip surface patch portion, 13 is a tongue surface patch portion, and 14a. , 14b are folded portions each having a plurality of folded portions.
FIG. 6 shows a shape having a cervical line on the outer peripheral surface of the lip surface application portion and the tongue surface application portion of the sheet. The folded portions 14a and 14b each have a width of 3 mm, a length of 25 mm, and the lip surface application portion 12 and the tongue. The surface pasting portion 13 has a different size, and FIG. 7 has the same shape as FIG. 6, but the folded portions 14a and 14b each have a width of 0.8 mm and a length of 20 mm.
8 and 9 show that the tooth neck line on the outer peripheral surface of the sheet has a gentle curved shape, the folded portions 14a and 14b have a width of 3 mm and 1 mm, a length of 30 mm and 15 mm, respectively, and the lip surface pasting portion 12 and the tongue surface. It is a shape from which the magnitude | size of the sticking part 13 differs.
FIG. 10 shows a rounded rectangle, FIG. 11 shows a substantially rectangular shape, and FIG. 12 shows a tooth neck line formed in a state where three concave portions are connected to the outer peripheral surface of the lip-applied portion of the sheet, and the whole is curved. FIG. 13 shows a shape in which the cervical line on the outer peripheral surface of the lip-applied portion of the sheet is formed in an arcuate shape, and the entire curve is curved with a gentle curve. FIG. 14 shows the lip-applied portion in the same manner as FIGS. And it is the shape which has a tooth neck part line in the outer peripheral surface of a tongue surface sticking part.

  10, 11, and 14, the size of the lip surface pasting portion 12 and the tongue surface pasting portion 13 are the same, and the line widths of the folded portions are all 3 mm. 10, 11, and 14, similarly to FIGS. 6 to 9, the lip surface pasting portion and the tongue surface pasting portion may have different sizes. In any case, the folded portion is cut at the central portion to be two, but may be connected to one.

  Furthermore, in the patch sheet of the present invention, as a means for improving the adhesion to the teeth or gums, one or a plurality of straight cut portions or the like are provided at locations other than the folded portion at the outer peripheral edge of the patch sheet. It is preferable to form. In this case, the length of one notch is preferably 1 to 14 mm. The number of notches can be freely set according to the size of the patch. Further, the length of each notch may be the same or different. The location of the incision is not specified on any side of the outer periphery of the patch, but the base of the lingual surface of the tongue surface and the base of the lip surface of the lip surface are desirable. It is desirable to put in.

  Moreover, you may cut out one place or several places of the outer periphery part of a sticking sheet, and you may form a notch part, such as a triangle shape, In this case, the maximum notch width of a notch part base end part is 2-15 mm, especially 2-8 mm, especially 2-4 mm are preferred. As the cut portion, it is particularly preferable to form a cut portion having the maximum cut width from the bottom toward the tooth method on the bottom side of the tongue surface sticking portion because it provides better adhesiveness and operability. If the maximum incision width is less than 2 mm, the adhesive sheets of the teeth overlap on the back side of the central incisor when folded back, resulting in poor use feeling of the applied sheet, and as a result, saliva is induced and the back of the tooth is applied during application. Adhesiveness may be reduced, and if it exceeds 15 mm, the contact area on the back side of the tooth is small, the adhesiveness to the back side of the tooth is reduced, and saliva is induced by the components dissolved from the adhesive layer and the feeling of use is reduced. There is a case. In the following, the notch width is the maximum notch width.

The cut shape is V-shaped, U-shaped, semi-circular, etc., and has a maximum width on the outer peripheral surface (cut end base end portion) of the sheet, and the cut portion is formed from the bottom of the application portion of the sheet toward the tooth method. A cut shape having a width that is not a straight line is preferable, and a V-shape is particularly preferable. The V-shaped tip portion is more preferably a semicircular shape or a trapezoidal shape with a radius of curvature of 0.5 mm or more, and is particularly effective when half-cutting described later. The length of the upper base of the trapezoid is preferably 0.5 to 1.5 mm. If the length of the upper base is less than 0.5 mm, it may be impossible to cut when half-cutting described later, and if it exceeds 1.5 mm, the back side of the tooth may not be sufficiently covered.
These cut lengths are preferably ½ or more of the vertical length of the folded portion as in the case of the straight cut, and more preferably cut to the vicinity of the folded line.

The notch of the tongue surface sticking portion is provided to facilitate sticking of the sheet to the tongue surface of the tooth or gum.
FIGS. 15-29 show the specific example of the sticking sheet which has various notches in the sticking sheet of this invention, 15 is a notch.
The cut shape is a straight line (FIG. 15), a V shape (FIGS. 16 to 19, the cut width is 3 mm in FIG. 16, 3 mm in FIG. 17, 2 mm in FIG. 18, and 10 mm in FIG. 19), and a U shape (FIG. 20). , A width of 3 mm), and the like, and it is preferable to provide at least one location, particularly at least one central portion of the tongue surface sticking portion. 16 and 17 are for the upper jaw and the lower jaw, respectively.
15 to 22 are all 3 mm. A plurality of cuts may be provided on a single tooth sticking sheet, and FIGS. 21 and 22 (cut width 3 mm) are cases where three straight lines and three V-shapes are provided, respectively.
Furthermore, in FIGS. 23-29, the sticking sheet | seat of the tooth | gear from which the shape which has a V-shaped cut | notch of 3 mm of cut widths was shown was shown. 23 to 29, the folding line width is 1 mm in FIG. 24 and 3 mm in the other cases. For example, in FIG. 15, the length of the linear cut is preferably 1/2 or more of the vertical length of the tooth back surface (tongue surface), more preferably to the vicinity of the folding line.

In the present invention, even when the tooth paste sheet is applied to the same number of teeth in the upper jaw and the lower jaw, the actual tooth size differs between the upper jaw and the lower jaw. Different sizes can be used for the forehead and lower forehead.
As a product form used simultaneously with the upper and lower jaws, the form of FIG. 30-1 is suitable. In FIG. 30A, 11a is an adhesive sheet for the upper jaw, 11b is an adhesive sheet for the lower jaw, and the adhesive layer of each of the adhesive sheets 11a and 11b on one side of the release liner 4 is a common release liner 4 It is coated with and becomes a set product. The upper and lower jaw sticking sheets both have a folding line width of 3 mm and a cut width of 3 mm. The upper jaw and the lower jaw may be set as a set, but the upper jaw and the lower jaw may be prepared separately and used as a separately packaged product. It is.

The adhesive patch sheet for teeth of the present invention has a release liner and a support bonded thereto via an adhesive layer, and the outer peripheral edge of the support together with the adhesive layer faces the release liner. It is preferable that it is pressed, and it is particularly preferable that it is pressed over the entire circumference of the outer peripheral edge. In this case, the outer peripheral edge of the support is preferably embossed so that the thickness of the pressure-sensitive adhesive layer is 0.05 to 0.5 mm.
Further, when the adhesive sheet has a shape that can cover both the lip surface and the tongue surface of the teeth or gums through the folded portion, the folded portion of the support is also embossed with the adhesive layer toward the release liner. In this case, the folded portion of the support is preferably embossed so that the thickness of the pressure-sensitive adhesive layer is 0.5 mm or less, and embossed until the thickness approaches 0 mm. It may be 0 mm.
Thus, the plaster composition which forms an adhesive layer from the outer peripheral edge of the support by its own weight or vibration during storage or transportation by embossing the outer peripheral edge of the support, and further the folded part. Can effectively be prevented from protruding.
The release liner is preferably larger than the support on which the pressure-sensitive adhesive layer is laminated.

  In the present invention, the thickness of the pressure-sensitive adhesive layer at the outer peripheral edge that is embossed is preferably 0.05 to 0.5 mm, and more preferably 0.05 to 0.2 mm. When the thickness of the pressure-sensitive adhesive layer on the outer peripheral edge is less than 0.05 mm, the paste composition for forming the pressure-sensitive adhesive layer may remain on the surface of the release liner during half-cutting. When the thickness of the layer exceeds 0.5 mm, the paste composition may protrude from the outer peripheral edge of the tooth sticking sheet due to its own weight or vibration during transportation.

  Further, the thickness of the pressure-sensitive adhesive layer of the folded portion that is embossed is preferably 0.5 mm or less, more preferably 0.01 to 0.2 mm, the thickness may be close to 0 mm, or 0 mm. Also good. When the thickness of the pressure-sensitive adhesive layer in the folded portion exceeds 0.5 mm, the plaster composition is too thick to be folded back and the operability at the time of application may be reduced.

The tooth patch sheet of the present invention is preferably prepared in a form in which two different sizes of tooth patch sheets are arranged on one release liner by performing a half cut process and half cutting. More preferably, the half-cut process is performed after the pushing process.
That is, in the half cut process, the support and the pressure-sensitive adhesive layer are cut from the support side of the tooth sticking sheet toward the release liner, and the release liner is half cut. Here, that the release liner is half cut means that a part of the thickness of the release liner is cut, and the release liner may be hardly cut.

Furthermore, in the case of half-cutting in the half-cutting step, the cut portion formed from the bottom to the tooth direction on the bottom of the tongue surface sticking portion covering the tongue surface of the tooth or gum is V-shaped, and V It is preferable that the tip portion of the character is semicircular or trapezoidal with a radius of curvature of 0.5 mm or more, and the length of the upper base of the trapezoidal shape is 0.5 to 1.5 mm. It is valid.
In this case, in a set product in which the upper and lower jaw patch sheets are covered with a single release liner, the interval between the two tooth patch sheets is preferably 3 to 15 mm in terms of production efficiency.

An example of a specific product form is FIG. 30-2, and FIG. 30-3 is a cross-sectional view along the broken line AA line of the sheet of FIG. 30-2. Fig. 30-2 shows a case where the upper and lower jaw sticking sheets as shown in Fig. 30-1 are covered with a single release liner to form a set product, and 11a is used for the upper jaw. The adhesive sheet 11b is a mandibular adhesive sheet, and the adhesive layer of each of the adhesive sheets 11a and 11b is larger than the adhesive sheet for the upper jaw and the lower jaw on one side of the release liner 4, and a single common release liner 4 is used. It is coated with and becomes a set product. In the upper jaw sticker sheet 11a, reference numerals 14a and 14b denote folded-back portions, and reference numeral 16a denotes an embossed outer peripheral edge portion of the sticker sheet. As shown in FIG. 30-3, in the case of the upper jaw adhesive sheet, the outer peripheral edge portion 16 a is embossed from the support 2 a side to the release liner 4 together with the adhesive layer 3 a, as shown in FIG. The thickness of the pressure-sensitive adhesive layer at the outer peripheral edge portion 16a is 0.12 mm, and the folded portion 14b is similarly embossed, and the thickness of the pressure-sensitive adhesive layer is 0.02 mm. The folded portion 14a in FIG. 30-2 is also stamped in the same manner. The same applies to the lower jaw patch sheet 11b. The outer peripheral edge portion 16b is embossed over the entire circumference, and the folded portions 14a and 14b are also embossed. The gap between the upper jaw patch sheet 11a and the lower jaw patch sheet 11b is 6 mm, and the upper and lower jaw patch sheets both have a folding line width of 3 mm. Reference numerals 15a and 15b denote V-shaped notches, which are semicircular with a notch width of 3 mm and a radius of curvature of the tip of 0.5 mm.
Moreover, FIG. 30-4 is an example of a form suitable for preparing the set product of FIG. 30-1 by half-cutting, and the notch parts 15a and 15b are V in the outer peripheral edge part of this sticking sheet 11a and 11b. The V-shaped tip has a trapezoidal shape, and the upper base of the trapezoid has a length of 1.0 mm.

The tooth sticking sheet in which the outer peripheral edge of the present invention is embossed can be prepared by the following method, but is not limited to such a preparation method. Hereinafter, the preparation method will be described by taking the broken line AA line of the maxillary patch sheet 11a in the set product of FIG. 30-2 as an example.
FIG. 30-5 is a partial schematic cross-sectional view showing a state in which a sheet coated with a plaster composition for forming an adhesive layer is embossed using an embossing roll between a support and a release liner. . As shown in FIG. 30-5, the embossing step is first performed according to the shape of the outer peripheral edge and the folded portion so that the pressure-sensitive adhesive layer has a desired thickness on the roll surface of the embossing roll 17. The outer peripheral edge portion 16a and the folded-back portion 14b of the adhesive sheet can be embossed with the pressure-sensitive adhesive layer 3a from the support 2a side toward the release liner 4 with the embossing 17a formed in this way. Next, as shown in FIG. 30-6, by half-cutting the vicinity of the center of the outer peripheral edge portion 16a that has been embossed from the support 2a side toward the release liner 4 together with the adhesive layer 3a (half-cut process) ), A patch sheet having a desired shape can be prepared.
It is also possible to prepare an all-cut type tooth sticking sheet by punching the vicinity of the center of the outer peripheral edge portion 16a of the sticking sheet embossed with the stamping 17a through the release liner from the support side. .

30-6 is a partial schematic cross-sectional view illustrating a state where the tooth sticking sheet in which the outer peripheral edge portion of FIG. 30-5 is embossed is cut with a blade of a half cutter. In the case of a half-cut type tooth sticking sheet, after embossing the outer peripheral edge portion 16a and the folded-back portion 14b as described above, as shown in FIG. 30-6, the center of the embossed outer peripheral edge portion 16a The vicinity can be prepared by cutting with a blade 18 of a half cutter. In this case, the support 2a and the pressure-sensitive adhesive layer 3a are completely cut, and the release liner 4 is cut to a part of its thickness, for example, about half. Is. Following cutting, the cut unnecessary support and plaster composition are removed, and finally the release liner 4 is punched out to a predetermined size using all cut rolls, whereby a set product can be prepared.
Further, as described above, the embossing step and the half-cutting step are performed by pressing with the embossing roll 17 as shown in FIG. 30-5 and then cutting with the half-cutter blade 18 as shown in FIG. 30-6. In this case, the half-cutting step is preferably a mold for embossing the half-cutter blade 18 and the folded-back part 14b for cutting the outer peripheral edge portion of the half-cut roll 19 as shown in FIG. 30-7. It is preferable in terms of production to use the one having the push 17a.
The shape of the embossing part 17a of the embossing roll and the half-cut roll is not particularly limited, but the corner of the embossing tip part contacting the support is preferably 0.5 mm or more in curvature radius. When the curvature radius is less than 0.5 mm, the support may be torn at the time of manufacturing a tooth sticking sheet or sticking to a tooth.

  In the adhesive sheet of the present invention, the pressure-sensitive adhesive layer can be covered with a release liner. The release liner can be used for the purpose of protecting the adhesive layer coated on the support until it is applied to the teeth or gums. For this reason, the adhesive sheet is preferably covered with the release liner.

  Since the material of the release liner affects the operability at the time of release, it is preferably one or more selected from polyesters such as polypropylene, polyethylene, polyethylene terephthalate, etc., more preferably these materials include wax, silicone, Teflon. A material obtained by applying a non-adhesive material such as a fluorine-based polymer such as (registered trademark) on one or both surfaces, and most preferably polyethylene terephthalate coated with silicone.

  Specifically, film binder 75E-0010DG new film, film binner 75E-0010GT new film, film binner 75E-0010BD, film binner 75E-0010BD new film, film binner 75E-0010GT, film binner 75E-0010GT (above, Fujimori Industry Co., Ltd. )), NS-75-A, NS-75-SA, NS-75-B (above, manufactured by Nakamoto Pax Co., Ltd.), SP-PET-O1-50-Bu (manufactured by East Cello Co., Ltd.) More preferably, it is 0.05 to 0.20 in terms of peelability. For example, film binder 75E-0010BD, film binder 75E-0010BD new hack, film binder 75E-0010GT, film binder 75E-0010DG (above, Fujimori Industry Co., Ltd.), N -75-A, NS-75-SA (manufactured by Nakamoto Pax Corp.) and the like.

  The coefficient of dynamic friction of the surface in contact with the pressure-sensitive adhesive layer of the release liner used in the present invention is preferably 0.05 to 0.24, particularly 0.05 to 0.20, as measured according to ASTM D 1894-95. . When the dynamic friction coefficient exceeds 0.24, the adhesive strength with the pressure-sensitive adhesive layer is too strong, and the peelability may decrease between the pressure-sensitive adhesive layer and the release liner, and the dynamic friction coefficient is less than 0.05. May easily peel off from the pressure-sensitive adhesive layer during spreading or storage.

  Since the thickness of the release liner also affects the operability during peeling, the thickness is preferably 25 to 200 μm, more preferably 35 to 100 μm. If the thickness exceeds 200 μm, the release liner may become too hard and the peelability may be reduced. When the thickness is less than 25 μm, not only the releasability is lowered, but also the release liner may be displaced during storage.

  Manufacture of these tooth sticking sheets can be carried out by applying a pressure-sensitive adhesive layer between the nonwoven fabric and the release liner, and then storing it as necessary, followed by half-cutting or all-cutting.

The pressure-sensitive adhesive layer of the tooth sticking sheet of the present invention can be formed of a plaster composition.
The plaster composition forming the pressure-sensitive adhesive layer is not particularly limited as long as it is an oral composition that has adhesiveness and can be fixed to a support, and is paste-like, cream-like, gel-like, gel-like, liquid, It can be prepared in the form of spray or rubber. In this case, as a compounding component, the well-known component according to a shape, a usage form, etc. can be mix | blended as needed. Specifically, it contains a gelling agent, a moisturizing agent, and a surfactant as an adhesive component, and further contains whitening ingredients, active ingredients such as various drugs, abrasives, fragrances, preservatives and the like as necessary. These components can be prepared by kneading with a solvent such as water.

Various gelling agents are used for the purpose of increasing the adhesiveness of the adhesive layer to teeth by gelling and pasting the plaster composition.
As the gelling agent used in the present invention, a water-soluble polymer substance is used. Gums such as native gellan gum, synthetic binders such as polyvinyl alcohol, sodium polyacrylate, carboxyvinyl polymer, polyvinyl pyrrolidone, polyethylene oxide, inorganic binders such as silica gel, aluminum silica gel, bee gum, laponite, thickening silica, etc. 1 type (s) or 2 or more types can be used. In this case, hydroxyethylcellulose, sodium carboxymethylcellulose, sodium alginate, carrageenan, xanthan gum, native gellan gum, polyvinyl alcohol, and carboxyvinyl polymer are preferably used as gelling agents that are less sticky or leaching in the mouth and have excellent usability. When hydroxyethyl cellulose and an alginate such as sodium alginate are used in combination, it is particularly desirable because it dissolves little and has a good feeling of use and can secure a high adhesive force to teeth.

  When the gelling agent is blended, the content is preferably 0.1 to 15%, particularly 0.5 to 10% of the entire composition because the pressure-sensitive adhesive layer can be attached and fixed to the tooth alone. If the content of the gelling agent is less than 0.1%, the adhesiveness to the teeth may be reduced, and the gelling agent may be eluted to reduce the feeling of use. If the content exceeds 15%, the pressure-sensitive adhesive layer is hard. It may become too much, and the adhesiveness to a tooth | gear and operativity may fall.

  Moisturizing agents such as sorbit, glycerin, ethylene glycol, propylene glycol, 1,3-butylene glycol, polyethylene glycol, polypropylene glycol, xylitol, maltitol, lactitol, etc. for the purpose of preventing the adhesive layer from drying and enhancing the feeling of use. One or more of the polyhydric alcohols may be blended.

  As the surfactant, an anionic surfactant, a nonionic surfactant, an amphoteric surfactant, and the like can be blended, and one or more of these can be used in combination.

  In this case, examples of the anionic surfactant include sodium alkyl sulfates such as sodium lauryl sulfate, sodium myristyl sulfate and sodium cetyl sulfate, sodium N-acyl glutamate such as sodium N-lauroyl glutamate, sodium N-palmitoyl glutamate, and N-lauroyl sarcosine. Sodium, sodium N-acyl sarcosine such as sodium N-myristoyl sarcosine, sodium N-lauroylmethyl taurine, sodium N-methyl-N-acyl taurine such as sodium N-myristoyl methyl taurine, sodium N-methyl-N-acylalanine, Sodium lauryl benzene sulfonate, hydrogenated coconut fatty acid monoglyceride sodium monosulfate, sodium lauryl sulfoacetate, α-o Sodium fins sulfonate, lauryl POE (polyoxyethylene) sulfate, sodium lauryl POE acetate, sodium lauryl POE phosphate, stearyl POE sodium phosphate and the like are used. In this case, sodium alkyl sulfate, sodium N-acyl glutamate, sodium N-acyl sarcosine, sodium N-methyl-N-acyl taurine and sodium N-methyl-N-acylalanine are preferably used.

  Nonionic surfactants include glycerin fatty acid esters such as monoglyceryl stearate and decaglyceryl laurate, sugar fatty acid esters such as sucrose fatty acid ester, maltose fatty acid ester, lactose fatty acid ester, maltitol fatty acid ester, lactitol fatty acid ester, etc. Sugar alcohol fatty acid ester, polyoxyethylene sorbitan monolaurate, polyoxyethylene sorbitan fatty acid ester such as polyoxyethylene sorbitan monostearate, polyoxyethylene fatty acid ester such as polyoxyethylene hydrogenated castor oil, myristic acid mono or diethanolamide, etc. Fatty acid ethanolamide, sorbitan fatty acid ester, polyoxyethylene higher alcohol ether, polyoxyethylene polyoxy Propylene copolymer, polyoxyethylene polyoxypropylene fatty acid ester or the like is used. In this case, polyoxyethylene fatty acid esters such as polyoxyethylene hydrogenated castor oil and polyoxyethylene higher alcohol ethers are preferably used.

  Zwitterionic surfactants include alkyldimethylaminoacetic acid betaines such as lauryldimethylaminoacetic acid betaine, N-alkyldiaminoethylglycine such as N-lauryldiaminoethylglycine, N-myristyldiaminoethylglycine, and N-alkyl-N-carboxyl. Methyl ammonium betaine, 2-alkyl-1-hydroxyethyl imidazoline betaine sodium and the like are used.

  The plaster composition for forming the adhesive layer used in the tooth patch sheet of the present invention can contain various drugs, for example, prevention / treatment of caries and hypersensitivity, food residue, stain Examples of applications include decomposition, sterilization, and sterilization of dirt and odorous substances typified by tobacco dust, dental plaque, tartar, bacteria, and specific drug substances, and effective active ingredients can be added to these. In addition, each component can be used in the range which does not inhibit the effect of this invention.

  As the whitening component, condensed phosphoric acid and / or a salt thereof can be blended for the purpose of removing stains on teeth. Examples of the condensed phosphoric acid and / or salt thereof include condensed phosphoric acid such as pyrophosphoric acid, tripolyphosphoric acid, and metaphosphoric acid, and salts such as alkali metal salts and alkaline earth metal salts thereof (particularly sodium salts or potassium salts). .

  The content of condensed phosphoric acid and / or a salt thereof is preferably 0.1 to 10%, particularly preferably 0.5 to 7%, in order to ensure a sufficient stain removing power. If the amount is less than 0.1%, the stain removing power may be insufficient. If the amount exceeds 10%, condensed phosphoric acid and / or a salt thereof precipitates and the stain removing power is lowered, and the whitening effect cannot be obtained satisfactorily. There is.

  Active ingredients suitably used for the adhesive layer include fluorine compounds such as sodium fluoride, alkali metal monofluorophosphate, tin fluoride, enzymes such as dextranase, mutanase, lysozyme, amylase, protease, xylitol, phosphorus Remineralization promoting components such as acid and Ca ion eluate, peroxides such as hydrogen peroxide, urea peroxide, calcium peroxide, potassium persulfate and sodium perborate, chelating agents such as EDTA, EHDP and phytic acid , Reducing agents such as ascorbic acid, organic acids such as citric acid, malonic acid, malic acid, succinic acid, kojic acid, polyethylene glycol, polyvinylpyrrolidone, ethanol, citral and benzaldehyde, cinnamic aldehyde, octanol, methyl salicylate, carvone, And these Dissolving agents such as fragrances that dissolve certain tobacco ani such as conductors, chlorhexidine salts, cetylpyridinium chloride, benzethonium chloride, benzalkonium chloride, triclosan, isopropylmethylphenol and other fungicides and antibacterial agents, rosemary, clove, sage, thyme, Herb extracts such as ougon, copper gluconate and the like.

  It also prevents or treats oral mucosal diseases such as periodontal tissue diseases such as gingivitis and alveolar pyorrhea, or stomatitis, or food residue that adheres to the gums as well as teeth, tobacco dust, dental plaque, tartar, bacteria, certain drug substances Degradation, sterilization, sterilization, removal and the like of dirt and odorous substances typified by the above are also mentioned as applications, and effective active ingredients can be added to these.

  In this case, preferable active ingredients include tranexamic acid, ε-aminocaproic acid, azulene, allantoin, dihydrocholestanol, glycyrrhizin salts, glycyrrhetinic acid, bisabolol, sodium chloride, potassium chloride, buckwheat extract, vitamin A, vitamin B2 Vitamins such as vitamin B6, vitamin C, vitamin D, vitamin E or derivatives thereof, enzymes such as dextranase, mutanase, lysozyme, amylase, protease, chelating agents such as EDTA, EHDP, phytic acid, reduction of ascorbic acid, etc. Agents, organic acids such as citric acid, malonic acid, malic acid, succinic acid, kojic acid, chlorhexidine salts, cetylpyridinium chloride, benzethonium chloride, benzalkonium chloride, triclosan, isopropylmethyl Disinfectant and antibacterial agents such as phenol, rosemary, clove, sage, thyme, herbal extracts such as Scutellaria, such as copper gluconate, and the like.

  The plaster composition forming the pressure-sensitive adhesive layer further includes perfumes such as menthol, anethole, carvone, peppermint oil, spearmint oil, preservatives such as benzoic acid and its sodium salt, parabens, red No. 3, red 104 No. 4, Yellow No. 4, Blue No. 1, Green No. 3, pigments or colorants such as mica titanium, petiole, sweeteners such as saccharin sodium, stevioside, glycyrrhizin, aspartame, and the like can be blended.

  Moreover, the plaster composition which forms the adhesive layer of this invention can also be used as a dentifrice by brushing as it is after use. When using as such a dentifrice, although an abrasive | polishing agent well-known in the said field | area can be used, it is preferable to mix | blend the abrasive | polishing agent which does not discharge | release polyvalent metal ions, such as a calcium ion. Examples of such abrasives include anhydrous silicic acid, aluminum silicate, zirconium silicate, insoluble sodium metaphosphate, bentonite, aluminum hydroxide, alumina, titanium oxide, crystalline cellulose, polymethyl methacrylate, and other synthetic resins. One or two or more of these can be used.

  In the case of a tooth patch sheet for the purpose of removing stains, brushing the stain with a dentifrice containing abrasive before applying the adhesive layer increases the permeability of the polyphosphate in the adhesive layer to the stain. Since it is promoted, it is a particularly preferred usage. In this case, the other dentifrice components are not particularly limited as long as the abrasive is contained, and the functions of the dentifrice and the adhesive layer are integrated by blending the abrasive into the adhesive layer. You can also

  The pH of the plaster composition forming the pressure-sensitive adhesive layer is not particularly limited as long as it is within the range of safety in the oral cavity and human body, but preferably pH 5.0 to 9.0 is preferable. Yes, including pH, sulfuric acid, nitric acid, citric acid, phosphoric acid, sodium hydroxide, potassium hydroxide, sodium carbonate, sodium citrate, sodium hydrogen citrate, sodium phosphate, sodium hydrogen phosphate, etc. Can do.

  The thickness of the pressure-sensitive adhesive layer is 0.1 to 3.0 mm, particularly 0.5 to 2.0 mm, particularly 0.6 to 1.6 mm is preferable in order to secure a thickness that can be stably applied to the tooth surface. . If the thickness of the adhesive layer is less than 0.1 mm, it cannot be applied firmly to the teeth, and if it exceeds 3.0 mm, it is too thick and the discomfort at the time of application to the teeth is too strong, and the mouth cannot be closed. The usability may be greatly impaired.

  The tooth sticking sheet of the present invention is excellent in use feeling at the time of sticking and can be applied for a long time. By fixing by spraying, adsorption, dipping, etc. and applying it to the oral cavity, high dental whitening effect, stain removal effect, anti-cariogenic effect, fluorine absorption effect, prevention of oral diseases such as gingivitis and alveolar pyorrhea, stomatitis, It exhibits a therapeutic effect, a dirt removing effect attached to teeth, gums, etc., and a bad breath removing effect. In addition to the form in which the pressure-sensitive adhesive layer and the support are integrated in advance as described above, the pressure-sensitive adhesive layer may be fixed to the support in use.

  EXAMPLES Hereinafter, although an Example and a comparative example are shown and this invention is demonstrated concretely, this invention is not restrict | limited to the following Example. In addition, all% in each example is the mass%.

Examples and comparative examples
The plaster composition shown in Table 1 was prepared by the following method, a three-layer support was prepared by the following method, and a tooth sticking sheet was prepared. Details of the three-layer support, pressure-sensitive adhesive layer (plaster composition), release liner, sheet shape and the like are as shown in Tables 2 to 5. The shape of a sticking sheet, the shape of a notch, etc. are as showing to FIGS.
The tooth sticking sheets shown in Tables 2 to 5 were evaluated by the following methods. The results are shown in Tables 2-5.

Preparation method of plaster composition;
The binder was added to the wetting agent while stirring, and distilled water in which a water-soluble substance was dissolved was further added. As needed, it adjusted using the pH buffer so that pH of the paste composition after preparation might be set to 5.0-9.0. Subsequently, an abrasive and a fragrance were sequentially added, and the pressure was reduced to 4 kPa and mixed until uniform. Once the pressure was returned to normal pressure, the surfactant was added, and then reduced in pressure to 4 kPa and mixed again to prepare a plaster composition. In addition, pH measured the pH of the plaster composition itself in 25 degreeC with the direct pH meter (Toa DKK Co., Ltd. product, HM-26S).

Method for preparing a three-layer support;
The three-layer support was prepared by the following method, for example. The three-layer supports used in Examples 1 to 32 and Comparative Examples 1 to 6 were prepared in the same manner as described below using the nonwoven fabrics shown in Tables 2 to 5.
Non-woven fabric, for example, polyethylene terephthalate nonwoven fabric (spun lace, manufactured by Shinwa Co., Ltd.) and rayon nonwoven fabric (spun lace, manufactured by Shinwa Co., Ltd.) are poured into the melted low density polyethylene and pressurized with a nip pressure of 1.0 kg. A three-layer support was obtained by fusing.
Note that Novatec LD manufactured by Nippon Polyethylene Co., Ltd. was used as the low density polyethylene.

Preparation method of tooth sticking sheet;
The plaster composition (pressure-sensitive adhesive layer) prepared by the above method is applied to the pressure-sensitive adhesive coated surface of the support, and the pressure-sensitive adhesive layer is coated with the support and the release liner silicone so as to have a predetermined thickness. Coating was performed as shown in FIG. 1 using a spreader (manufactured by Kaei Machine Industry Co., Ltd., roll sand coater) while being sandwiched between the surfaces. Next, the upper jaw was cut to a width of 62 mm and a vertical width of 25 mm, the lower jaw was cut to a width of 52 mm and a vertical width of 24 mm, and the shape shown in Table 2 was cut into a tooth paste sheet.
A sheet without a release liner is prepared by peeling only the release liner from the tooth patch sheet prepared by the above method, or by applying a plaster composition using a spatula or the like on the adhesive-coated surface of the support. did.

The dynamic friction coefficient of the release liner was measured by the following method.
Dynamic friction coefficient measurement method The dynamic friction coefficient measurement method is in accordance with ASTM D 1894-95, and when the silicone coat direction of each release liner is the longitudinal direction of the film roll, SP-2000 (manufactured by IMASS) is used in the longitudinal direction. Measured film-to-film.
The obtained patch sheet was evaluated by the following method. The results are shown in Tables 2-5.

Peelability of release liner, feeling of use during application, discomfort due to saliva accumulated during application, adhesiveness to the back side of teeth immediately after application, adhesiveness to the back side (tongue surface) of applied teeth, application Operability evaluation of the time
The release liner was peeled from the tooth sticking sheet, and the release property of the release liner was evaluated.
Next, operability was evaluated when the adhesive sheet with the release liner peeled was folded and applied so as to cover the front lip surface and tongue surface of the subject's upper and lower jaws 3-3.
After pasting for 3 minutes, the feeling of use and sticking during that time (feeling of being uncomfortable due to saliva staying during sticking, sticking to the back side of the tooth immediately after sticking, sticking to the back side of the tooth during sticking) were evaluated. After 3 minutes, the tooth sticking sheet was peeled off, and the sticking site was brushed with a toothbrush using the adhesive layer remaining on the tooth surface.

Evaluation of stain removal effect;
After evaluating the peelability, feeling of use, discomfort, adhesiveness and operability of the release liner, the stain removal effect was evaluated.
First, photograph the subject's upper and lower jaw 3-3 front anterior labial surface and tongue surface before applying the tooth application sheet, and divide the target tooth into 4 parts and compare each with 4 color standards. The initial stain density was visually evaluated in 7 stages. Next, once a day, affixing a sticking sheet for 3 minutes in the same manner as described above, brushing is performed for 5 consecutive days, a photograph is taken again on the last day, and the same color standard as the initial evaluation is used. Stain adhesion after the treatment was visually evaluated.
The stain removal effect was obtained by subtracting the score after treatment from the initial score for each division unit, calculating the average rate of change per division for each subject, and calculating the average value of 10 subjects.

The evaluation criteria for each evaluation item were as follows.
"Peelability of release liner"
A: The pressure-sensitive adhesive layer does not adhere to the release liner at all and can be easily removed.
○: The pressure-sensitive adhesive layer slightly adheres to the part where the release liner has begun to peel off, but it can be easily peeled off and is not a problem.
Δ: Adhesive layer considerably adheres to the release liner.
X: The pressure-sensitive adhesive layer adheres to the entire surface of the release liner.

"Ease of operation when pasting"
(Double-circle): The sticking position is easy to understand and it is easy to return to the back side of a tooth.
○: The sticking position is somewhat difficult to understand, or it is difficult to turn back to the back side of the tooth, but it is a problem level.
△: It takes time to apply the sticking position because it is difficult to understand or it is difficult to fold back to the back of the tooth.
×: It is difficult to apply the application because the application position is very difficult to understand or it is very difficult to return to the back side of the tooth.

"Usage feeling of the attached sheet"
A: There is a feeling that the sheet is stuck, but the lips can be opened and closed smoothly and not uncomfortable.
○: The sheet is somewhat bulky, but it is not uncomfortable because the mouth can be closed.
Δ: The mouth is closed somehow, but it is bulky and uncomfortable.
X: The mouth is not closed, and the contact feeling of the adhesive sheet against the mucous membrane is uncomfortable.

"Uncomfortable feeling due to saliva accumulated during application"
A: The saliva staying in the oral cavity is not concerned at all.
○: There is a slight level of saliva staying in the oral cavity, but there is no problem.
(Triangle | delta): The saliva staying in the oral cavity is somewhat worrisome.
X: A lot of saliva staying in the oral cavity is very worrisome.

"Adhesion to the back side (lingual side) of teeth immediately after application"
A: Fix to teeth without re-pasting.
○: Fix to teeth by re-applying once.
(Triangle | delta): It fixes to a tooth | gear by reapplying 2-3 times.
X: Not fixed to teeth.

"Adhesion to the back side (lingual side) of the tooth being applied"
A: No slippage or peeling during application.
○: Although it feels slightly raised, it does not peel off during application and is at a satisfactory level.
Δ: Slightly deviates during sticking but does not peel off.
X: Peeled during application.

"Stain removal effect"
A: The average rate of change of the scores of 10 subjects is 0.20 or more. O: The average rate of change of the scores of 10 subjects is 0.10 or more and less than 0.20. Δ: The average rate of change of the scores of 10 subjects is 0.00. 05 or more and less than 0.10 x: Average change rate of 10 subjects' scores is less than 0.05

"Comprehensive evaluation"
◎: ◎ for all evaluation items.
◯: There are no “x” and “Δ” in all evaluation items, and any item has one or more ◎ and ◯.
Δ: There is no cross in all evaluation items, and there is one or more Δ in any evaluation item.
X: There is x in any evaluation item.

  Hereinafter, details of the support, release liner, shape and the like used in Examples and Comparative Examples described in Tables 2 to 5 are shown. In the table, Na is sodium.

Support A: Between polyethylene terephthalate nonwoven fabric (Shinwa Co., Ltd., 7840A, spun lace, basis weight 40 g / m ² ) and rayon nonwoven fabric (Shinwa Co., Ltd., 7140A, spun lace, basis weight 40 g / m ² ) A three-layer nonwoven fabric with low-density polyethylene (thickness 20 μm) interposed. The overall thickness of the support A is 0.41 mm.
Support B: Between a polyethylene terephthalate nonwoven fabric (Shinwa Co., Ltd., 7850A, spun lace, basis weight 50 g / m ² ) and a rayon nonwoven fabric (Shinwa Co., Ltd., 7140A, spun lace, basis weight 40 g / m ² ) A three-layer nonwoven fabric with low-density polyethylene (thickness 20 μm) interposed.
Support C: Between polyethylene terephthalate nonwoven fabric (Shinwa Co., Ltd., 7840A, spun lace, basis weight 40 g / m ² ) and rayon nonwoven fabric (Shinwa Co., Ltd., 7140A, spun lace, basis weight 40 g / m ² ) A three-layer nonwoven fabric interposing polypropylene (thickness 15 μm).

Support D: Low density between polypropylene nonwoven fabric (Shinwa Co., Ltd., spunlace, basis weight 40 g / m ² ) and rayon nonwoven fabric (Shinwa Corp., 7140A, spunlace, basis weight 40 g / m ² ) A three-layer nonwoven fabric interposing polyethylene (thickness 20 μm).
Support E: Between polyethylene terephthalate nonwoven fabric (Shinwa Co., Ltd., 7840A, spun lace, basis weight 40 g / m ² ) and rayon nonwoven fabric (Shinwa Co., Ltd., 7140A, spun lace, basis weight 40 g / m ² ) A three-layer nonwoven fabric with low-density polyethylene (thickness 30 μm) interposed.
Support F: Between a polyethylene terephthalate nonwoven fabric (Shinwa Co., Ltd., 7830A, spun lace, basis weight 30 g / m ² ) and a rayon nonwoven fabric (Shinwa Co., Ltd., 7160A, spun lace, basis weight 60 g / m ² ) A three-layer nonwoven fabric with low-density polyethylene (thickness 20 μm) interposed.

Support G: Between polyethylene terephthalate nonwoven fabric (Shinwa Co., Ltd., 7840A, spun lace, basis weight 40 g / m ² ) and rayon nonwoven fabric (Shinwa Co., Ltd., 7160A, spun lace, basis weight 60 g / m ² ) A three-layer nonwoven fabric with low-density polyethylene (thickness 20 μm) interposed.
Support H: Between polyethylene terephthalate nonwoven fabric (Shinwa Co., Ltd., 7830A, spun lace, basis weight 30 g / m ² ) and rayon nonwoven fabric (Shinwa Co., Ltd., 7140A, spun lace, basis weight 40 g / m ² ) A three-layer nonwoven fabric with low-density polyethylene (thickness 20 μm) interposed.
Support I: Low between rayon nonwoven fabric (Shinwa Co., Ltd., 7140A, spun lace, basis weight 40 g / m ² ) and rayon nonwoven fabric (Shinwa Co., Ltd., 7140A, spun lace, basis weight 40 g / m ² ) A three-layer nonwoven fabric interposing density polyethylene (thickness 20 μm).

Support J: Between polyethylene terephthalate nonwoven fabric (Shinwa Co., Ltd., 7840A, spun lace, basis weight 40 g / m ² ) and rayon nonwoven fabric (Shinwa Co., Ltd., 7140A, spun lace, basis weight 40 g / m ² ) A three-layer nonwoven fabric with low-density polyethylene (thickness 35 μm) interposed.
Support K: Between polyethylene terephthalate nonwoven fabric (Shinwa Co., Ltd., 7840A, spun lace, basis weight 40 g / m ² ) and rayon nonwoven fabric (Shinwa Co., Ltd., 7140A, spun lace, basis weight 40 g / m ² ) A three-layer nonwoven fabric with low-density polyethylene (thickness 5 μm) interposed.
Support L: Between polyethylene terephthalate nonwoven fabric (Shinwa Co., Ltd., 7840A, spunlace, basis weight 40 g / m ² ) and polyethylene terephthalate nonwoven fabric (Shinwa Co., Ltd., 7840A, spunlace, basis weight 40 g / m ² ) A three-layer nonwoven fabric in which low density polyethylene (thickness 20 μm) is interposed.

Support M: Between polyethylene terephthalate nonwoven fabric (Shinwa Co., Ltd., 7840A, spun lace, basis weight 40 g / m ² ) and rayon nonwoven fabric (Shinwa Co., Ltd., Hibon 4220, chemical bond, basis weight 20 g / m ² ) A three-layer nonwoven fabric in which low density polyethylene (thickness 20 μm) is interposed.
Support N; polyethylene terephthalate nonwoven fabric (Shinwa Corp., 7840A, spun lace, having a basis weight 40 g / m ²⁾ and, nonwoven mass ratio of rayon / polypropylene = 7/3 (Nippon Vilene Co., EW 4070, a spun lace, and a basis weight of 70 g / m ² ), a three-layer nonwoven fabric in which low-density polyethylene (thickness 20 μm) is interposed.
Support O: Polyethylene terephthalate nonwoven fabric (Shinwa Co., Ltd., 7840A, spun lace, basis weight 40 g / m ² ), and nonwoven fabric with mass ratio of rayon / polypropylene = 7/3 (Shinwa Co., Ltd., 7140-6) , Spunlace, and 40 g / m ² ), a three-layer nonwoven fabric in which low-density polyethylene (thickness 20 μm) is interposed.

Support P: Polyethylene terephthalate nonwoven fabric (manufactured by Shinwa Co., Ltd., 7840A, spunlace, basis weight 40 g / m ² ) and nonwoven fabric with mass ratio of rayon / polyethylene terephthalate / polypropylene = 25/60/15 (Nippon Vilene Co., Ltd.) ), EW-550, spun lace, basis weight 55 g / m ² ), and a three-layer nonwoven fabric in which low-density polyethylene (thickness 20 μm) is interposed.
Support Q; polyethylene terephthalate nonwoven fabric (Idemitsu Unitech Co., RN2040, spunbonded, basis weight 40 g / m ²⁾ and rayon nonwoven fabric (Shinwa Corp., 7140A, spun lace, having a basis weight 40 g / m ²⁾ between A three-layer nonwoven fabric with low-density polyethylene (thickness 20 μm) interposed.
Support R: Non-woven fabric having a mass ratio of polyethylene terephthalate / rayon = 8/2 (manufactured by Shinwa Co., Ltd., spun lace, basis weight 40 g / m ² ), rayon non-woven fabric (manufactured by Shinwa Co., Ltd., 7140A, spun lace, A three-layer nonwoven fabric in which low-density polyethylene (thickness 20 μm) is interposed between the weight per unit weight 40 g / m ² ).

Support S: Nonwoven fabric having a mass ratio of polyethylene terephthalate / rayon = 5/5 (manufactured by Shinwa Co., Ltd., span lace, basis weight 70 g / m ² ), rayon nonwoven fabric (manufactured by Shinwa Co., Ltd., 7140A, spun lace, A three-layer nonwoven fabric in which low-density polyethylene (thickness 20 μm) is interposed between the weight per unit weight 40 g / m ² ).
Support T: Non-woven fabric having a mass ratio of polyethylene terephthalate / rayon = 35/65 (manufactured by Shinwa Co., Ltd., spun lace, basis weight 40 g / m ² ), rayon non-woven fabric (manufactured by Shinwa Co., Ltd., 7140A, spun lace, A three-layer nonwoven fabric in which low-density polyethylene (thickness 20 μm) is interposed between the weight per unit weight 40 g / m ² ).
Support U: Polyethylene terephthalate nonwoven fabric (Shinwa Co., Ltd., 7840A, spun lace, basis weight 40 g / m ² ) and nonwoven fabric with mass ratio of rayon / polypropylene = 5/5 (Shinwa Co., Ltd., spun lace, A three-layer nonwoven fabric in which low-density polyethylene (thickness 20 μm) is interposed between the weight per unit weight 40 g / m ² ).

Release liner A; polyethylene terephthalate film coated with silicone on one side (manufactured by Fujimori Kogyo Co., Ltd., film binder 75E-0010BD Nyuhaku, coefficient of dynamic friction 0.19, thickness 75 μm).
Release liner B: Polyethylene terephthalate film coated with silicone on one side (manufactured by Nakamoto Pax Co., Ltd., E20 NS series Sepa A, coefficient of dynamic friction 0.20, thickness 75 μm).
Release liner C: polyethylene terephthalate film coated with silicone on one side (manufactured by Fujimori Kogyo Co., Ltd., film binder 75E-0010BD, coefficient of dynamic friction 0.07, thickness 75 μm).
Release liner D: Polyethylene terephthalate film coated with silicone on one side (manufactured by Fujimori Kogyo Co., Ltd., film binder 75E-0010DG Nyuhaku, coefficient of dynamic friction 0.22, thickness 75 μm).

  From the above results, the tooth or gum sticking sheet of the present invention has an excellent feeling of use at the time of sticking to the tooth, there is no dissolution of the components in the adhesive layer by saliva, and due to high adhesiveness to the teeth It was confirmed that it could be held in the oral cavity. Moreover, it discovered that it could peel easily from an adhesive layer by using the peeling liner which has a specific dynamic friction coefficient. Furthermore, when the tooth | gear or gum sticking sheet | seat of this invention was used for the stain removal, it became clear that it has a high stain removal effect.

  Next, the following patch sheets (Examples 33 to 39) were prepared in the same manner as described above and evaluated in the same manner. The method for preparing the three-layer support is the same as described above, and a low-density polyethylene (manufactured by Nippon Polyethylene Co., Ltd.) heated and dissolved between a polyethylene terephthalate nonwoven fabric or a rayon / polyethylene terephthalate = 70/30 nonwoven fabric and a rayon nonwoven fabric. , Novatec LD), and pressure-fused at a nip pressure of 1.0 kg to obtain a three-layer support.

Example 33
The adhesive layer was spread so as to have a thickness of 1.1 mm so as to be sandwiched between the polyethylene terephthalate surface of the support and the silicone-treated surface of the release liner. Next, this was half-cut into a size of 62 mm in width and 25 mm in length for the upper jaw, 52 mm in width and 24 mm in length for the lower jaw, and in the shape shown in FIG. .

The results were as follows.
Release property of release liner: ◎
Usability of the sheet being affixed: ◎
Discomfort due to saliva accumulated during application: ◎
Adhesion to the back of teeth immediately after application: ◎
Adhesion to the back side of the tooth being applied: ◎
Ease of operation when pasting: ◎
Stain removal effect: ◎

<Support>
Adhesive surface: Polyethylene terephthalate (40 g / m ² per unit area, spun lace, Shinwa Co., Ltd., 7840A)
Barrier layer: Low density polyethylene 20μm
Saliva absorption surface: rayon (40 g / m ² per unit area, spunlace, manufactured by Shinwa Co., Ltd., 7140A)
Support thickness: 0.36 mm
<Release liner>
Single-sided silicone-coated polyethylene terephthalate (thickness 75 μm, dynamic friction coefficient 0.19, manufactured by Fujimori Kogyo Co., Ltd., film binder 75E-0010BD)

<Adhesive layer>
Sodium tripolyphosphate (produced by Taihei Chemical Industry Co., Ltd.) 1%
Hydroxyethyl cellulose (Daicel Chemical Industries, SE850) 2.4%
Sodium alginate (manufactured by Kibun Food Chemifa, Duck Algin NSPM)
1.2%
Thickening silica (Tokuyama, Tokuyama Co., Ltd.) 3%
Silicic anhydride (Ineos Corporation, SORBOSIL AC77) 25%
70% Sorbit (Chuo Kasei Co., Ltd.) 36%
Polyoxyethylene (20) hydrogenated castor oil 2%
(Aoki Yushi Kogyo Co., Ltd., BROWNON RCW-20)
Sodium lauryl sulfate (manufactured by Toho Chemical Industry Co., Ltd., Scope MP-90N)
0.5%
Saccharin sodium 0.04%
Fragrance 0.7%
Water balance
Total 100.0%
Coating thickness: 0.6mm

Example 34
The preparation and evaluation methods of the following tooth sticking sheets were performed in the same manner as in the previous examples.
The adhesive layer was spread so as to have a thickness of 0.5 mm so as to be sandwiched between the polyethylene terephthalate surface of the support and the silicone-treated surface of the release liner. Next, this was cut into a size of 55 mm in width and 20 mm in length for the upper jaw, 45 mm in width and 20 mm in length for the lower jaw, and cut into the shape shown in FIG. .

The results were as follows.
Release property of release liner: ◎
Usability of the sheet being affixed: ○
Discomfort due to saliva accumulated during application: ◎
Adhesion to the back side of teeth immediately after application: ○
Adhesiveness to the back side of teeth during application: ○
Ease of operation when pasting: ○
Stain removal effect: ○

<Support>
Adhesive surface: Polyethylene terephthalate (40 g / m ² per unit area, spun lace, Shinwa Co., Ltd., 7840A)
Barrier layer: Low density polyethylene 20μm
Saliva absorption surface: rayon (40 g / m ² per unit area, spunlace, manufactured by Shinwa Co., Ltd., 7140A)
Support thickness: 0.44 mm
<Release liner>
Single-sided silicone-coated polyethylene terephthalate (thickness 25 μm, dynamic friction coefficient 0.11, manufactured by Fujimori Kogyo Co., Ltd., 25E-0010GT)

<Adhesive layer>
Sodium tripolyphosphate (produced by Taihei Chemical Industry Co., Ltd.) 1%
Hydroxyethylcellulose (Daicel Chemical Industries, SE850)
3.6%
Sodium alginate (manufactured by Kibun Food Chemifa, Duck Algin NSPM)
1.8%
Thickening silica (Tokuyama, Tokuyama Co., Ltd.) 3%
Silicic anhydride (Ineos Corporation, SORBOSIL AC77) 25%
70% Sorbit (Chuo Kasei Co., Ltd.) 36%
Polyoxyethylene (20) hydrogenated castor oil 1%
(Aoki Yushi Kogyo Co., Ltd., BROWNON RCW-20)
Sodium lauryl sulfate (manufactured by Toho Chemical Industry Co., Ltd., Scope MP-90N)
0.5%
Saccharin sodium 0.04%
Fragrance 0.5%
Water balance
Total 100.0%
Coating thickness: 1.6mm

Example 35
The preparation and evaluation methods of the following tooth sticking sheets were performed in the same manner as in the previous examples.
The adhesive layer was spread so as to have a thickness of 2.0 mm so as to be sandwiched between the polyethylene terephthalate surface of the support and the silicone-treated surface of the release liner. Next, this was cut into a size of 70 mm in width and 30 mm in length for the upper jaw, 60 mm in width and 30 mm in width for the lower jaw, and cut into the shape shown in FIG. .

The results were as follows.
Release property of release liner: ◎
Usability of the sheet being affixed: ○
Discomfort due to saliva accumulated during application: ○
Adhesion to the back side of teeth immediately after application: ○
Adhesiveness to the back side of teeth during application: ○
Ease of operation when pasting: ○
Stain removal effect: ○

<Support>
Adhesive surface: Polyethylene terephthalate (40 g / m ² per unit area, spun lace, Shinwa Co., Ltd., 7840A)
Barrier layer: Low density polyethylene 20μm
Saliva absorption surface: rayon (40 g / m ² per unit area, spunlace, manufactured by Shinwa Co., Ltd., 7140A)
Support thickness: 0.40 mm
<Release liner>
Single-sided silicone-coated polyethylene terephthalate (thickness 50 μm, dynamic friction coefficient 0.07, manufactured by Fujimori Kogyo Co., Ltd., film binder 50E-0010BD)

<Adhesive layer>
Sodium tripolyphosphate (produced by Taihei Chemical Industry Co., Ltd.) 4%
Hydroxyethylcellulose (Daicel Chemical Industries, SE850)
2.4%
Sodium alginate (manufactured by Kibun Food Chemifa, Duck Algin NSPM)
1.2%
Thickening silica (Tokuyama, Tokuyama Co., Ltd.) 3%
Silicic anhydride (Ineos Corporation, SORBOSIL AC77) 20%
70% Sorbit (Chuo Kasei Co., Ltd.) 35%
Ethanol (manufactured by Shinwa Alcohol Industry Co., Ltd., 95 degree first grade specified alcohol)
10%
Polyoxyethylene (20) hydrogenated castor oil 1%
(Aoki Yushi Kogyo Co., Ltd., BROWNON RCW-20)
Sodium lauryl sulfate (manufactured by Toho Chemical Industry Co., Ltd., Scope MP-90N)
2%
Saccharin sodium 0.04%
Fragrance 1.1%
Water balance
Total 100.0%
Coating thickness: 1.1mm

Example 36
The preparation and evaluation methods of the following tooth sticking sheets were performed in the same manner as in the previous examples.
The adhesive layer was spread so as to have a thickness of 3.0 mm so as to be sandwiched between the polyethylene terephthalate surface of the carrier and the silicone-treated surface of the release liner. Next, this was cut into a size of 62 mm in width and 25 mm in length for the upper jaw, 52 mm in width and 24 mm in width for the lower jaw, and the shape shown in FIG. .

The results were as follows.
Release property of release liner: ◎
Usability of the sheet being affixed: ○
Discomfort due to saliva accumulated during application: ○
Adhesion to the back of teeth immediately after application: ◎
Adhesion to the back side of the tooth being applied: ◎
Ease of operation when pasting: ○
Stain removal effect: ◎

<Support>
Adhesive surface: Polyethylene terephthalate (40 g / m ² per unit area, spun lace, Shinwa Co., Ltd., 7840A)
Barrier layer: Low density polyethylene 20μm
Saliva absorption surface: rayon (40 g / m ² per unit area, spunlace, manufactured by Shinwa Co., Ltd., 7140A)
Support thickness: 0.40 mm
<Release liner>
Single-sided silicone-coated polyethylene terephthalate (thickness 50 μm, dynamic friction coefficient 0.07, manufactured by Fujimori Kogyo Co., Ltd., film binder 50E-0010BD)

<Adhesive layer>
Sodium tripolyphosphate (produced by Taihei Chemical Industry Co., Ltd.) 1%
Hydroxyethylcellulose (Daicel Chemical Industries, SE850)
2.0%
Sodium alginate (manufactured by Kibun Food Chemifa, Duck Algin NSPM)
1.0%
Thickening silica (Tokuyama, Tokuyama Co., Ltd.) 3%
Silicic anhydride (Ineos Corporation, SORBOSIL AC77) 25%
70% Sorbit (Chuo Kasei Co., Ltd.) 44%
Polyoxyethylene (20) hydrogenated castor oil 2%
(Aoki Yushi Kogyo Co., Ltd., BROWNON RCW-20)
Sodium lauryl sulfate (manufactured by Toho Chemical Industry Co., Ltd., Scope MP-90N)
0.5%
Saccharin sodium 0.04%
Fragrance 0.5%
Water balance
Total 100.0%
Coating thickness: 0.9mm

Example 37
The preparation and evaluation methods of the following tooth sticking sheets were performed in the same manner as in the previous examples.
The adhesive layer was spread so as to have a thickness of 0.1 mm so as to be sandwiched between the polyethylene terephthalate surface of the support and the silicone-treated surface of the release liner. Next, this was cut into a size of 80 mm in width and 35 mm in length for the upper jaw, 70 mm in width and 35 mm in height for the lower jaw, and cut into a shape shown in FIG. .

The results were as follows.
Release property of release liner: ◎
Usability of the sheet being affixed: ○
Discomfort due to saliva accumulated during application: ◎
Adhesion to the back side of teeth immediately after application: ○
Adhesiveness to the back side of teeth during application: ○
Ease of operation when pasting: ◎
Stain removal effect: ○

<Support>
Adhesive surface: Polyethylene terephthalate (40 g / m ² per unit area, spun lace, Shinwa Co., Ltd., 7840A)
Barrier layer: Low density polyethylene 20μm
Saliva absorbing surface: rayon (40 g / m ² per unit area, spun lace, manufactured by Shinwa Co., Ltd., 7140A)
Support thickness: 0.40 mm
<Release liner>
Single-sided silicone-coated polyethylene terephthalate (thickness 50 μm, dynamic friction coefficient 0.07, manufactured by Fujimori Kogyo Co., Ltd., film binder 50E-0010BD)

<Adhesive layer>
Sodium tripolyphosphate (produced by Taihei Chemical Industry Co., Ltd.) 1%
Hydroxyethylcellulose (Daicel Chemical Industries, SE850)
2.0%
Sodium alginate (manufactured by Kibun Food Chemifa, Duck Algin NSPM)
1.0%
Thickening silica (Tokuyama, Tokuyama Co., Ltd.) 3%
Silicic anhydride (Ineos Corporation, SORBOSIL AC33) 10%
Silicic anhydride (Ineos Corporation, SORBOSIL AC36) 15%
70% Sorbit (Chuo Kasei Co., Ltd.) 44%
Polyoxyethylene (20) hydrogenated castor oil 2%
(Aoki Yushi Kogyo Co., Ltd., BROWNON RCW-20)
Sodium lauryl sulfate (manufactured by Toho Chemical Industry Co., Ltd., Scope MP-90N)
0.5%
Saccharin sodium 0.04%
Fragrance 0.5%
Water balance
Total 100.0%
Coating thickness: 1.3mm

Example 38
The preparation and evaluation methods of the following tooth sticking sheets were performed in the same manner as in the previous examples.
The adhesive layer was spread so as to have a thickness of 1.6 mm so as to be sandwiched between the polyethylene terephthalate surface of the support and the silicone-treated surface of the release liner. Next, this was cut to a width of 50 mm and a length of 15 mm for the upper jaw, a width of 40 mm and a length of 15 mm for the lower jaw, and a shape shown in FIG. .

The results were as follows.
Release property of release liner: ◎
Usability of the sheet being affixed: ◎
Discomfort due to saliva accumulated during application: ◎
Adhesion to the back of teeth immediately after application: ◎
Adhesion to the back side of the tooth being applied: ◎
Ease of operation when pasting: ◎
Stain removal effect: ○

<Support>
Adhesive coated surface: rayon / polyethylene terephthalate = 70/30
(Weight per unit 40 g / m ² , Spunlace, Shinwa Co., Ltd., 7840A)
Barrier layer: Low density polyethylene 20μm
Saliva absorption surface: rayon (40 g / m ² per unit area, spunlace, manufactured by Shinwa Co., Ltd., 7140A)
Support thickness: 0.34 mm
<Release liner>
Single-sided silicone-coated polyethylene terephthalate (thickness 50 μm, dynamic friction coefficient 0.07, manufactured by Fujimori Kogyo Co., Ltd., film binder 50E-0010BD)

<Adhesive layer>
Sodium pyrophosphate (produced by Taihei Chemical Industry Co., Ltd.) 1%
Hydroxyethylcellulose (Daicel Chemical Industries, SE850)
2.0%
Sodium alginate (manufactured by Kibun Food Chemifa, Duck Algin NSPM)
1.0%
Thickening silica (Tokuyama, Tokuyama Co., Ltd.) 3%
Silicic anhydride (Ineos Corporation, SORBOSIL AC33) 10%
Silicic anhydride (Ineos Corporation, SORBOSIL AC36) 15%
70% Sorbit (Chuo Kasei Co., Ltd.) 44%
Polyoxyethylene (20) hydrogenated castor oil 2%
(Aoki Yushi Kogyo Co., Ltd., BROWNON RCW-20)
Sodium lauryl sulfate (manufactured by Toho Chemical Industry Co., Ltd., Scope MP-90N)
0.5%
Saccharin sodium 0.04%
Fragrance 0.5%
Water balance
Total 100.0%
Coating thickness: 1.1mm

Example 39
The preparation and evaluation methods of the following tooth sticking sheets were performed in the same manner as in the previous examples.
The adhesive layer was spread so as to have a thickness of 0.6 mm so as to be sandwiched between the polypropylene surface of the support and the silicone-treated surface of the release liner. Next, this was cut into a size of 60 mm in width and 25 mm in length for the upper jaw, 50 mm in width and 24 mm in length for the lower jaw, and cut into a shape shown in FIG. .

The results were as follows.
Release property of release liner: ◎
Usability of the sheet being affixed: ○
Discomfort due to saliva accumulated during application: ◎
Adhesion to the back side of teeth immediately after application: ○
Adhesiveness to the back side of teeth during application: ○
Ease of operation when pasting: ○
Stain removal effect: ○

<Support>
Adhesive surface: Polyethylene terephthalate (40 g / m ² per unit area, spun lace, Shinwa Co., Ltd., 7840A)
Barrier layer: Low density polyethylene 20μm
Saliva absorbing surface: rayon (40 g / m ² per unit area, spun lace, manufactured by Shinwa Co., Ltd., 7140A)
Support thickness: 0.46 mm
<Release liner>
Single-sided silicone-coated polyethylene terephthalate (thickness 50 μm, dynamic friction coefficient 0.07, manufactured by Fujimori Kogyo Co., Ltd., film binder 50E-0010BD)

<Adhesive layer>
Sodium pyrophosphate (produced by Taihei Chemical Industry Co., Ltd.) 1%
Hydroxyethylcellulose (Daicel Chemical Industries, SE850)
2.0%
Sodium alginate (manufactured by Kibun Food Chemifa, Duck Algin NSPM)
1.0%
Thickening silica (Tokuyama, Tokuyama Co., Ltd.) 3%
Silicic anhydride (Ineos Corporation, SORBOSIL AC33) 10%
Silicic anhydride (Ineos Corporation, SORBOSIL AC36) 15%
70% Sorbit (Chuo Kasei Co., Ltd.) 36%
Polyoxyethylene (20) hydrogenated castor oil 2%
(Aoki Yushi Kogyo Co., Ltd., BROWNON RCW-20)
Sodium lauryl sulfate (manufactured by Toho Chemical Industry Co., Ltd., Scope MP-90N)
0.5%
Saccharin sodium 0.04%
Fragrance 0.7%
Water balance
Total 100.0%
Coating thickness: 1.1mm

[Examples 40 to 48]
In the same manner as described above, the plaster composition (adhesive layer) shown in Table 6 was applied using a spreader, and further a stamping and half-cutting process was performed to prepare a tooth sticking sheet. The embossing and half-cutting steps were performed as follows. That is, as shown in FIG. 30-5, a release liner is used from the support side of the adhesive sheet by using an embossing roll and embossing formed on the roll surface according to the outer peripheral edge shape and the folded portion shape of each adhesive sheet. After embossing the outer peripheral edge and the folded part toward the surface, as shown in FIG. 30-7, according to the shape of the half cutter blade formed on the roll surface according to the outer peripheral edge shape of each adhesive sheet, and the shape Using a half-cut roll equipped with an embossing for the folded portion, it was cut into a desired shape (the support and the pressure-sensitive adhesive layer were completely cut, and the release liner was partially cut off). Thereafter, unnecessary support and plaster composition were removed, and finally the release liner was punched out to a predetermined size using all the cut rolls to prepare an adhesive sheet (set product).
Details of the obtained adhesive sheet are shown in Table 6. These patch sheets were evaluated in the same manner as described above, and further evaluated for production suitability by half-cutting and protrusion of the plaster composition during transportation. The results are shown in Table 6.

Evaluation of manufacturing suitability by half-cut:
When removing the unneeded plaster composition and support produced during the half-cut in the half-cut process, the presence or absence of uncut cuts connected without being cut and the amount of the plaster composition remaining on the release liner were visually observed. evaluated. Next, the tooth patch sheet was peeled off from the release liner, and the degree of tearing when the tooth patch sheet was pulled in the vertical and horizontal directions was evaluated according to the following criteria.

Evaluation criteria for manufacturing suitability by half-cut:
A: The support is cut without being left uncut, the plaster composition does not remain on the release liner, and the support does not tear.
◯: The support was cut without being left uncut, but the plaster composition remained slightly on the release liner or frayed on the support. However, it is a level with no problem.
X: Uncut residue is observed on the support, a large amount of the paste composition remains on the release liner, or the support is torn.

Evaluation of the protrusion of the plaster composition from the outer periphery of the sheet After the adhesive sheet was transported back and forth between Tokyo and Osaka, the amount of protrusion of the plaster composition from the outer periphery of the sheet was visually evaluated according to the following criteria.

Evaluation Criteria for Extruding Plaster Composition from Outer Periphery Edge of Sheet: No protrusion of the plaster composition is observed at the outer peripheral edge of the sheet.
○: Although the protrusion of the plaster composition of 1.0 mm or less is seen on the outer peripheral edge of the sheet, there is no particular discomfort in appearance.
X: The paste composition having a thickness of more than 1.0 mm is seen on the outer peripheral edge of the sheet, and the appearance is uncomfortable.

注：表６中の先端部形状における０．５Ｒは、曲率半径０．５ｍｍを示す。

Note: 0.5R in the tip shape in Table 6 indicates a curvature radius of 0.5 mm.

  From the above results, it was revealed that the tooth sticking sheet of the present invention is excellent in production suitability by half-cut and can suppress the protrusion of the plaster composition from the outer peripheral edge of the sheet by transportation.

DESCRIPTION OF SYMBOLS 1 Adhesive sheet 2 Support body 3 Adhesive layer 4 Release liner 5 Spunlace nonwoven fabric containing polyethylene terephthalate or polypropylene (A)
6 Polyethylene or polypropylene layer (C)
7 Spunlaced non-woven fabric containing rayon (B)
DESCRIPTION OF SYMBOLS 11 Adhesive sheet 11a Upper jaw adhesive sheet 11b Lower jaw adhesive sheet 12 Lip surface adhesive part 13 Tongue surface adhesive parts 14a, 14b Folding parts 15a, 15b Notch parts 16a, 16b Outer peripheral edge part 17 Embossing roll 17a Embossing 18 Half cutter Blade 19 Half cut roll

Claims (14)

  A patch sheet for teeth or gums comprising a support and a plaster composition having adhesiveness to teeth or gums, wherein the support comprises a spunlace nonwoven fabric (A) containing polyethylene terephthalate or polypropylene; A spunlace nonwoven fabric (A) having a three-layer structure in which a polyethylene or polypropylene layer (C) having a thickness of 10 to 30 μm is interposed between the spunlace nonwoven fabric (B) containing rayon and containing the polyethylene terephthalate or polypropylene An adhesive sheet for teeth or gums, wherein an adhesive layer made of a plaster composition is formed thereon.   The tooth or gum sticking sheet has a shape capable of covering both the lip surface and the tongue surface of the tooth or gum via the folded portion, and the line width of the folded portion is 0.5 to 5 mm. The sticking sheet for teeth or gums according to claim 1 characterized by the above-mentioned.   3. A tooth or gum for a tooth or gum according to claim 2, wherein a notch having a maximum width of 2 to 15 mm is formed from the base toward the tooth toward the bottom of the tongue surface sticking part covering the tongue surface of the tooth or gum. Affixed sheet.   The adhesive sheet formed on the spunlace nonwoven fabric (A) containing polyethylene terephthalate or polypropylene is coated with a release liner, The adhesive sheet for teeth or gums according to claim 1, 2, or 3.   The adhesive sheet for teeth or gums according to claim 4, wherein the release liner is made of a material selected from polyethylene terephthalate, polyethylene, and polypropylene, and has a dynamic friction coefficient of 0.05 to 0.24.   The tooth or gum sticking sheet according to any one of claims 1 to 5, wherein the plaster composition forming the adhesive layer is an adhesive oral composition containing an alginate and hydroxyethyl cellulose.   The adhesive sheet for teeth or gums according to claim 6, wherein the plaster composition further contains condensed phosphoric acid and / or a salt thereof.   5. A release liner and a support bonded thereto via a pressure-sensitive adhesive layer, and the outer peripheral edge of the support is pressed together with the pressure-sensitive adhesive layer toward the release liner. The tooth or gum sticking sheet according to any one of 7 above.   The tooth or gum sticking sheet according to claim 8, wherein the outer peripheral edge of the support is embossed so that the thickness of the pressure-sensitive adhesive layer is 0.05 to 0.5 mm.   Furthermore, when the said support body has a folding | returning part, this folding | turning part is embossed with the adhesive layer toward the peeling liner, The sticking sheet for teeth or gums of Claim 8 or 9.   Furthermore, the sticking sheet for teeth or gums according to claim 10, wherein the folded portion of the support is embossed so that the thickness of the pressure-sensitive adhesive layer is 0.5 mm or less.   The adhesive sheet for teeth or gums according to any one of claims 4 to 11, wherein the release liner is larger than the support.   The sticking sheet for teeth or gums according to any one of claims 4 to 12, wherein the support and the pressure-sensitive adhesive layer are cut from the support side toward the release liner, and the release liner is half-cut.   A semicircular shape in which the cut portion formed from the base toward the tooth direction is V-shaped and the tip of the V-shaped is a radius of curvature of 0.5 mm or more at the bottom of the tongue surface sticking portion covering the tongue surface of the tooth or gum Or the sticking sheet for teeth or gums of Claim 13 which is trapezoid shape.

Images