JP2010096748A5 - - Google Patents
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- Publication number
- JP2010096748A5 JP2010096748A5 JP2009174692A JP2009174692A JP2010096748A5 JP 2010096748 A5 JP2010096748 A5 JP 2010096748A5 JP 2009174692 A JP2009174692 A JP 2009174692A JP 2009174692 A JP2009174692 A JP 2009174692A JP 2010096748 A5 JP2010096748 A5 JP 2010096748A5
- Authority
- JP
- Japan
- Prior art keywords
- periostin
- integrin
- amount
- gene
- expression level
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 101710199268 Periostin Proteins 0.000 claims 49
- 102100037765 Periostin Human genes 0.000 claims 41
- 102000006495 integrins Human genes 0.000 claims 25
- 108010044426 integrins Proteins 0.000 claims 25
- 238000000034 method Methods 0.000 claims 18
- 210000004027 cell Anatomy 0.000 claims 17
- 239000000126 substance Substances 0.000 claims 16
- 230000014509 gene expression Effects 0.000 claims 10
- 206010012438 Dermatitis atopic Diseases 0.000 claims 8
- 201000008937 atopic dermatitis Diseases 0.000 claims 8
- 239000012472 biological sample Substances 0.000 claims 6
- 210000002510 keratinocyte Anatomy 0.000 claims 6
- 230000004069 differentiation Effects 0.000 claims 5
- 230000000694 effects Effects 0.000 claims 5
- 230000035755 proliferation Effects 0.000 claims 5
- 239000003814 drug Substances 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 239000002157 polynucleotide Substances 0.000 claims 3
- 102000040430 polynucleotide Human genes 0.000 claims 3
- 108091033319 polynucleotide Proteins 0.000 claims 3
- 230000000069 prophylactic effect Effects 0.000 claims 3
- 238000012216 screening Methods 0.000 claims 3
- 229940124597 therapeutic agent Drugs 0.000 claims 3
- 230000023441 thymic stromal lymphopoietin production Effects 0.000 claims 3
- 102100031294 Thymic stromal lymphopoietin Human genes 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 239000000523 sample Substances 0.000 claims 2
- 108010029307 thymic stromal lymphopoietin Proteins 0.000 claims 2
- 201000004624 Dermatitis Diseases 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 238000003018 immunoassay Methods 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 210000003491 skin Anatomy 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009174692A JP5522717B2 (ja) | 2008-09-19 | 2009-07-27 | アトピー性皮膚炎の検出方法および予防・治療剤のスクリーニング方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008241295 | 2008-09-19 | ||
| JP2008241295 | 2008-09-19 | ||
| JP2009174692A JP5522717B2 (ja) | 2008-09-19 | 2009-07-27 | アトピー性皮膚炎の検出方法および予防・治療剤のスクリーニング方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010096748A JP2010096748A (ja) | 2010-04-30 |
| JP2010096748A5 true JP2010096748A5 (enExample) | 2011-09-22 |
| JP5522717B2 JP5522717B2 (ja) | 2014-06-18 |
Family
ID=42258523
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009174692A Active JP5522717B2 (ja) | 2008-09-19 | 2009-07-27 | アトピー性皮膚炎の検出方法および予防・治療剤のスクリーニング方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP5522717B2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130096028A1 (en) * | 2010-06-28 | 2013-04-18 | Tohoku University | Cell capable of expressing tslp constantly and at high level, and method for screening for tslp modulator utilizing the cell |
| EP3447491A3 (en) | 2010-12-16 | 2019-06-05 | F. Hoffmann-La Roche AG | Diagnosis and treatments relating to th2 inhibition |
| MX2013010977A (es) | 2011-03-31 | 2013-10-30 | Procter & Gamble | Sistema, modelos y metodos para identificar y evaluar agentes dermoactivos eficaces para tratar la caspa/dermatitis seborreica. |
| JP5871228B2 (ja) | 2011-10-31 | 2016-03-01 | 国立大学法人佐賀大学 | 慢性副鼻腔炎の検出方法 |
| JP2015527630A (ja) | 2012-06-06 | 2015-09-17 | ザ プロクター アンド ギャンブルカンパニー | ヘア／頭皮ケア組成物向け化粧剤の同定システム及び方法 |
| JP2015535807A (ja) * | 2012-08-15 | 2015-12-17 | ザ プロクター アンド ギャンブルカンパニー | 皮膚疾患の配列の治療に有効な皮膚活性剤を特定及び評価するためのシステム、モデル、及び方法 |
| US20160304866A1 (en) * | 2013-09-27 | 2016-10-20 | Aqua Therapeutics Co., Ltd. | Drug for Disease Caused by Expression of Periostin Except Eye Disease, and Use Thereof |
| WO2018030451A1 (ja) * | 2016-08-09 | 2018-02-15 | 学校法人大阪医科薬科大学 | 癒着治療薬、癒着の治療方法、術後癒着マーカー、および術後癒着の罹患の可能性を試験する方法 |
| KR102309982B1 (ko) * | 2016-10-25 | 2021-10-12 | 코스맥스 주식회사 | 곡정초 추출물을 함유하는 아토피 피부염 개선용 피부 외용제 조성물 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69322860T2 (de) * | 1992-04-03 | 1999-07-01 | Genentech, Inc., South San Francisco, Calif. | Antikörper gegen alpha v beta 3 integrin |
| DE69637395T2 (de) * | 1995-09-11 | 2008-12-18 | La Jolla Cancer Research Foundation, La Jolla | Moleküle, die sich in ausgewählten Organen oder Geweben in-vivo einfinden |
| JP2003534558A (ja) * | 2000-05-26 | 2003-11-18 | グラクソ グループ リミテッド | ＬＡＰ（潜在型結合ペプチド）とインテグリンαｖβ３との間の相互作用のモジュレーターを同定する方法及びその医学的使用 |
| JP4155561B2 (ja) * | 2000-12-26 | 2008-09-24 | 国立大学法人佐賀大学 | アレルギー性疾患検査方法 |
-
2009
- 2009-07-27 JP JP2009174692A patent/JP5522717B2/ja active Active
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