JP2010063622A - Apparatus for medicinal preparation - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide an apparatus for medicinal preparation capable of preparing a medicinal agent by an easy usage. <P>SOLUTION: The apparatus for medicinal preparation has vial mounting parts 21 and 31 capable of mounting a vial, an open part 51, a flow path forming part 70, and a check valve 86. The open part 51 is provided between the vial mounting parts 21 and 31 and left open to an outer space. The flow path forming part 70 has needle-like tip parts 71 and 76 arranged on the vial mounting parts 21 and 31, respectively. An air flow path 82 extending between the tip parts 71 and 76 and communicating with the open part 51 on the path, and a communicating flow path 81 independent to the air flow path 82 and extending between the tip parts 71 and 76 are formed in the flow path forming part 70. The check valve 86 is arranged on a path of the air flow path 82, and selectively interrupts either between the open part 51 and the vial mounting part 21 or between the open part 51 and the vial mounting part 31. <P>COPYRIGHT: (C)2010,JPO&INPIT

Description

  TECHNICAL FIELD The present invention generally relates to a drug preparation device, and more specifically, to a drug preparation device (transfer) for mixing a freeze-dried solid drug and a lysis solution and taking out the obtained drug into a syringe. Needle).

  Regarding a conventional drug preparation device, for example, Japanese Patent Publication No. 2006-527024 discloses a reconstitution device intended to reconstitute a multi-component material using a commercially available component storage container. (Patent Document 1).

  FIG. 12 is a cross-sectional view showing the reconstruction device disclosed in Patent Document 1. As shown in FIG. Referring to FIG. 12, the reconstruction device 100 includes a receiver 112, a receiver 114, a device body 116 positioned therebetween, and a withdrawal interface 118 extending from the device body 116. The withdrawal interface 118 is selectively sealed by a removable cap 156. Inside the receiver 112 is a first component cannula 132 having a first pointed tip 134 and inside the receiver 114 is a second component cannula 148 having a second pointed tip 150. Yes.

  The withdrawal interface 118 forms a withdrawal orifice 158 that communicates with the withdrawal port 136 through a withdrawal lumen 160 located in the first component cannula 132. An additional travel lumen 164 extends through the device body 116 and communicates the first component cannula 132 and the second component cannula 148. The exhaust port 178 forms an exhaust orifice 180 that communicates with the exhaust port 152 through an exhaust lumen 182 located in the second component cannula 148.

  In the reconfigurable device 100 having such a configuration, a first container filled with a solid component is mounted in the receiver 112, and a second container filled with a liquid component is mounted in the receiver 114. At this time, the negative pressure difference between the first container and the second container is used to cause the liquid component to move from the second container to the first container through the moving lumen 164. During this time, air flows from the exhaust port 178 through the exhaust lumen 182 into the container, thereby replacing the liquid component between the first container and the second container.

When mixing and dissolution of the liquid and solid components occurs, the cap 156 is removed from the withdrawal interface 118 and the withdrawal injection is connected. Pulling back on the plunger of the withdrawal injection causes movement of material from the first container into the injection.
JP-T-2006-527024

  In the reconstruction device 100 disclosed in Patent Document 1 described above, by attaching the first container filled with the solid component to the receiver 112 and attaching the second container filled with the liquid component to the receiver 114, Solid and liquid components can be prepared and the drug can be withdrawn and removed for injection. However, in the reconstitution device 100, the mounting position of the container for storing the solid component and the liquid component, respectively, is determined as either the receiver 112 or the receiver 114. For this reason, if each container is not attached to a predetermined receptacle, preparation may not be performed properly, or preparation work may be complicated due to recovery.

  Accordingly, an object of the present invention is to solve the above-mentioned problems and to provide a drug preparation device that enables preparation of a drug by a simple method of use.

  A drug preparation device according to the present invention is a drug preparation device for preparing a drug by mixing contents arranged in a plurality of vials having an internal pressure difference. The drug preparation device includes a first vial mounting part and a second vial mounting part in which a vial can be mounted, an opening part, a flow path forming part, and a valve body. The opening part is provided between the first vial mounting part and the second vial mounting part, and is opened to the external space. The flow path forming part has a needle-like first tip part and second tip part respectively disposed on the first vial mounting part and the second vial mounting part. The flow path forming portion includes a first flow path that extends between the first front end portion and the second front end portion and communicates with the open portion on the path, and the first front end is independent of the first flow path. And a second flow path extending between the first tip and the second tip. A valve body is arrange | positioned on the path | route of a 1st flow path. The valve body selectively blocks either one of the opening portion and the first vial mounting portion and between the opening portion and the second vial mounting portion.

  According to the medicine preparation device configured as described above, by mounting the vials on the first vial mounting unit and the second vial mounting unit, respectively, from a vial having a relatively large internal pressure (hereinafter referred to as a positive pressure vial). The contents are transferred to a vial having a relatively low internal pressure (hereinafter referred to as a negative pressure vial) through the second flow path. At this time, in order to maintain the airtightness of the negative pressure vial, the valve body shuts off the opening portion from the vial mounting portion to which the negative pressure vial is mounted, and air flows into the negative pressure vial from the opening portion. To regulate.

  In the present invention, a valve body that selectively blocks either the opening portion and the first vial mounting portion or between the opening portion and the second vial mounting portion is provided on the path of the first flow path. Therefore, even if a positive pressure vial or a negative pressure vial is attached to either the first vial attachment part or the second vial attachment part, the valve body causes air to flow from the open part into the negative pressure vial. Can be regulated. As a result, the user can prepare the medicine by a simple method of use without losing the attachment position of the vial.

  Preferably, the medicine preparation device further includes a syringe connection part that is provided between the first vial attachment part and the second vial attachment part and is capable of connecting a syringe. The second flow path communicates with the syringe connection part on the path.

  According to the medicine preparation device configured as described above, the prepared medicine can be taken out from the vial into the syringe by connecting the syringe to the syringe connecting portion.

  Preferably, the valve body is movable by gravity between a position where the opening portion and the first vial mounting portion are blocked and a position where the opening portion and the second vial mounting portion are blocked. Provided.

  According to the medicine preparation device configured as described above, since the mechanism for driving the valve body is not necessary, the medicine preparation device can be configured simply.

  Preferably, the medicine preparation device further includes an air filter provided at a position where the opening portion communicates with the first flow path. On the path of the first flow path, the valve body can be moved between a position for blocking between the opening portion and the first vial mounting portion and a position for blocking between the opening portion and the second vial mounting portion. Thus, a space to be accommodated is formed. The space is partitioned from the open portion by an air filter.

  According to the medicine preparation device configured as described above, the medicine preparation device can be configured simply by forming a space for accommodating the valve body using an air filter that prevents foreign substances from entering the inside of the vial.

  As described above, according to the present invention, it is possible to provide a drug preparation device that enables preparation of a drug by a simple method of use.

  Embodiments of the present invention will be described with reference to the drawings. In the drawings referred to below, the same or corresponding members are denoted by the same reference numerals.

  FIG. 1 is a side view showing a drug preparation device according to an embodiment of the present invention. FIG. 2 is a view of the drug preparation device in FIG. 1 as viewed from above and below. FIG. 3 is a cross-sectional view showing the drug preparation device in FIG. 4 is a cross-sectional view showing a vial attached to the drug preparation device in FIG.

  With reference to FIGS. 1 to 4, the drug preparation device 10 mixes the solution stored in the solution vial 91 and the solid drug stored in the drug vial 96, and mixes the prepared drug with a syringe. It is an instrument for taking out. Hereinafter, the structure of the medicine preparation device 10 will be described.

  With reference to FIG. 1 to FIG. 3, first, the appearance of the drug preparation device 10 will be described. The drug preparation device 10 has a columnar appearance as a whole. The drug preparation device 10 includes a vial mounting part 21, a vial mounting part 31, and an intermediate part 41.

  One of the dissolution solution vial 91 and the drug vial 96 is mounted on the vial mounting part 21, and one of the solution solution vial 91 and the drug vial 96 is mounted on the vial mounting part 31. . The vial mounting part 21 and the vial mounting part 31 are respectively arranged at both ends in the cylindrical axial direction. The vial mounting part 21 and the vial mounting part 31 have the same shape.

  The intermediate part 41 is disposed between the vial mounting part 21 and the vial mounting part 31. A luer member 63 and a cap 65 are connected to the intermediate portion 41 when the drug preparation device 10 is not used. The luer member 63 may be formed integrally with the intermediate portion 41.

  The vial mounting part 21 has a cylindrical part 22. The cylindrical portion 22 has a bottomed cylindrical shape in which one end is opened and the other end is closed by the intermediate portion 41, and the mounting opening 23 is formed inside thereof. The vial mounting part 31 has a cylindrical part 32. The cylindrical portion 32 has a bottomed cylindrical shape whose one end is opened to the opposite side to the cylindrical portion 22 and the other end is closed by the intermediate portion 41, and the mounting port 33 is formed inside thereof. The mounting port 23 and the mounting port 33 have shapes that allow the vials to be attached and detached.

  The drug preparation device 10 has a flow path forming unit 70. The flow path forming unit 70 has a shape extending in one direction between the vial mounting unit 21 and the vial mounting unit 31. The flow path forming unit 70 is formed so as to penetrate the intermediate portion 41 from the vial mounting portion 21 and reach the vial mounting portion 31.

  The flow path forming unit 70 has a tip portion 71 and a tip portion 76. The distal end 71 and the distal end 76 have a needle shape so that the rubber stoppers 93 and 98 (see FIG. 4) of the vial can be inserted. The distal end portion 71 and the distal end portion 76 are provided at both ends where the flow path forming portion 70 extends toward the vial mounting portion 21 and the vial mounting portion 31, respectively. The distal end portion 71 and the distal end portion 76 are disposed inside the mounting opening 23 and the mounting opening 33, respectively.

  In the drug preparation device 10 according to the present embodiment, the vial mounting part 21, the vial mounting part 31, the intermediate part 41, and the flow path forming part 70 are integrally formed of a resin material. Without being limited to such a configuration, for example, the drug preparation device 10 may be formed of metal, only the flow path forming portion 70 (tip portions 71 and 76) is formed of metal, and other portions are resin materials. May be formed. As the material used for the drug preparation device 10, a material that does not adversely affect the drug such as elution into the drug is used. For example, polyethylene, polypropylene, polycarbonate, ABS (acrylonitrile butadiene styrene), cyclic polyolefin, Polyacetal, stainless steel, etc. are used.

  In the figure, the drug preparation device 10 having a cylindrical appearance and the vial mounting portions 21 and 31 having the same shape is illustrated, but the drug preparation device in the present invention is in such a form. It is not limited. The external appearance of the medicine adjusting device is not particularly limited as long as it does not interfere with the adjustment operation, and the vial mounting part 21 and the vial mounting part 31 may have different shapes. The shape of the mounting opening is not particularly limited as long as the vial is detachable. As a preferred form of the mounting port, the mounting ports 23 and 33 having an inner diameter substantially the same as the outer diameter of the opening of the vial are shown in the figure. For example, the mounting port is located outside the opening of the vial. You may have the square shape of the side of substantially the same length as a diameter.

  Next, the internal structure of the drug preparation device 10 will be described with reference to FIG. 3. The drug preparation device 10 includes an open part 51 and a syringe connection part 61. The opening part 51 and the syringe connection part 61 are formed in the intermediate part 41.

  The open part 51 includes an intake flow path 52 through which air can flow. The intake passage 52 is formed in the intermediate portion 41 in a form opened to the external space. The intake flow path 52 extends in the radial direction with respect to the axis along which the flow path forming portion 70 extends, and opens to the external space on the outer periphery thereof. A filter 53 is provided on the path of the intake flow path 52. The filter 53 prevents foreign matter from entering the inside of the vial attached to the drug preparation device 10.

  A cap (not shown) may be provided so as to close the opening of the intake flow path 52. The cap is provided to protect the state of the drug preparation device 10 when not in use. The cap may be provided in the form of a seal attached to the intermediate portion 41 so as to close the opening of the intake flow path 52.

  The syringe connection part 61 includes a drug suction channel 62 through which a drug can flow. The medicine suction channel 62 is formed in the intermediate portion 41 in a form opened to the external space. The drug suction flow path 62 extends in the radial direction with respect to the axis along which the flow path forming portion 70 extends, and opens to the external space on the outer periphery thereof. The drug suction flow path 62 is formed in a phase shifted from the intake flow path 52 around the axis along which the flow path forming portion 70 extends.

  A foreign matter removal filter for removing foreign matter in the medicine sucked by the syringe may be provided on the route of the medicine suction flow path 62.

  A tubular luer member 63 is connected to the medicine suction channel 62, and a cap 65 is provided so as to close the opening of the luer member 63. The luer member 63 functions as a connector for enabling a syringe to be connected to the syringe connecting portion 61. The cap 65 is provided to hold the drug suction flow path 62 in a sealed state, and is removed when the syringe is connected.

  In the flow path forming unit 70, a communication flow path 81 and an air flow path 82 are formed. The communication channel 81 and the air channel 82 extend between the tip portion 71 and the tip portion 76. The communication flow path 81 and the air flow path 82 extend in the axial direction in which the flow path forming portion 70 extends, and open to the mounting opening 23 and the mounting opening 33 at both ends thereof. The communication flow path 81 and the air flow path 82 are formed in phases shifted from each other around the axis along which the flow path forming portion 70 extends. The communication flow path 81 and the air flow path 82 are formed so as to communicate with the drug suction flow path 62 and the inhalation flow path 52, respectively.

  The drug preparation device 10 has a check valve 86. The check valve 86 is disposed on the path of the air flow path 82. The check valve 86 selectively blocks either the vial mounting part 21 and the opening part 51 or between the vial mounting part 31 and the opening part 51. Hereinafter, the form in which the check valve 86 is provided will be described in detail.

  FIG. 5 is an enlarged cross-sectional view of a range surrounded by a two-dot chain line V in FIG. With reference to FIGS. 3 and 5, an accommodation space 88 for accommodating the check valve 86 is formed on the path of the air flow path 82.

  The form in which the accommodation space 88 is provided will be described. The accommodation space 88 is formed so as to partially enlarge the flow path cross-sectional area of the air flow channel 82 in the accommodation space 88. The accommodation space 88 is defined by the filter 53 and the wall portion 43 that defines the air flow path 82. The filter 53 defines a space between the accommodation space 88 and the intake flow path 52. The wall 43 is provided so as to protrude toward the drug suction channel 62. The wall part 43 is provided so that it may overlap on the line which the communication flow path 81 extends.

  The air flow path 82 includes a first portion 82p extending from the storage space 88 toward the vial mounting portion 21 and a second portion 82q extending from the storage space 88 toward the vial mounting portion 31.

  The check valve 86 has a spherical shape. The total height H of the accommodation space 88 in the direction in which the air flow path 82 extends is larger than the diameter of the check valve 86. With such a configuration, the check valve 86 has a position that blocks the opening of the first portion 82p of the air flow channel 82 and a position that blocks the opening of the second portion 82q of the air flow channel 82 by the action of gravity. It is provided so that it can move between.

  That is, when the posture of the medicine preparation device 10 is such that the vial mounting part 31 is positioned vertically downward and the vial mounting part 21 is positioned vertically upward, the check valve 86 disposed in the accommodation space 88 is Then, it moves to a position that closes the opening of the second portion 82q of the air flow channel 82. Thereby, the air flow between the vial mounting part 31 and the opening part 51 is regulated, and the air flow between the vial mounting part 21 and the opening part 51 is allowed.

  On the other hand, when the vial preparation unit 31 is positioned vertically upward and the vial attachment unit 21 is positioned vertically downward, the check valve 86 disposed in the accommodation space 88 is positioned in the posture of the medicine preparation device 10. Then, it moves to a position that closes the opening of the first portion 82p of the air flow channel 82. Thereby, the air flow between the vial mounting part 31 and the opening part 51 is permitted, and the air flow between the vial mounting part 21 and the opening part 51 is regulated.

  In the present embodiment, the case where the check valve 86 having a spherical shape is used has been described. However, the valve body in the present invention is not limited to this. The valve body in the present invention is not limited as long as it can selectively block either the vial mounting part 21 and the opening part 51 or between the vial mounting part 31 and the opening part 51. The shape of the stop valve 86 may be changed to a pillar shape or a flat plate shape, or a butterfly valve whose one end is rotatably supported may be used instead of the check valve 86. Further, the shape of the accommodation space 88 and the wall 43 is appropriately changed in accordance with the change in the shape of the check valve 86.

  The basic structure of the drug preparation device 10 according to the embodiment of the present invention will be described collectively. The drug preparation device 10 includes a vial mounting portion 21 and a second vial mounting portion as a first vial mounting portion to which a vial can be mounted. As a vial mounting part 31, an opening part 51 provided between the vial mounting part 21 and the vial mounting part 31 and opened to the external space, and a needle disposed in each of the vial mounting part 21 and the vial mounting part 31 A first tip portion 71 as a first tip portion and a tip portion 76 as a second tip portion, and extends between the tip portion 71 and the tip portion 76 and communicates with the opening 51 on the path. A flow in which an air flow channel 82 as a flow channel and a communication flow channel 81 as a second flow channel extending between the tip portion 71 and the tip portion 76 are formed independently of the air flow channel 82. Road shape A valve that is disposed on the path of the part 70 and the air flow path 82 and selectively shuts off either the opening part 51 and the vial mounting part 21 or between the opening part 51 and the vial mounting part 31 And a check valve 86 as a body.

  Next, a method for preparing a drug using the drug preparing device 10 in FIG. 1 will be described. 6 to 11 are cross-sectional views showing the steps of a method for preparing a drug using the drug preparing device in FIG.

  With reference to FIG. 4, first, as a pre-stage of the preparation process, a drug preparation device 10, a solution vial 91 and a drug vial 96 to be attached to the drug preparation device 10 are prepared.

  The dissolution liquid vial 91 includes a glass bottle 92 and a rubber stopper 93 that closes the opening of the glass bottle 92. The drug vial 96 has the same structure as the solution vial 91 and is composed of a glass bottle 97 and a rubber stopper 98. Inside the lysis solution vial 91, a liquid lysis solution is sealed. A solid drug freeze-dried is enclosed inside the drug vial 96.

  The inside of the drug vial 96 is in a vacuum state. For this reason, the internal pressure of the drug vial 96 is lower than the internal pressure of the dissolution liquid vial 91.

  The inside of the drug vial 96 does not necessarily need to be in a strict vacuum state. As a result of the negative pressure inside the drug vial 96, an internal pressure difference is generated between the drug vial 96 and the solution vial 91. As long as it has occurred. In the present embodiment, a case is described in which a vial for enclosing a liquid and a vial for enclosing a solid are attached to the drug preparation device 10. However, the present invention is not limited to such a mode of use. One vial may be attached to the drug preparation device 10.

  Next, referring to FIG. 6, the dissolution liquid vial 91 is mounted on the vial mounting portion 21. At this time, the posture of the drug preparation device 10 is not particularly limited, but preferably, the dissolution liquid vial 91 is placed on a desk or the like, and the vial mounting portion 21 is mounted from above the dissolution liquid vial 91. As the lysate vial 91 is attached, the distal end portion 71 of the flow path forming unit 70 penetrates the rubber stopper 93, and the air flow path 82 and the communication flow path 81 communicate with the inside of the lysate vial 91.

  Referring to FIG. 7, the posture of the drug preparation device 10 is next set in a state where the vial mounting part 21 to which the dissolution liquid vial 91 is mounted is positioned vertically upward and the vial mounting part 31 is positioned vertically downward. And The check valve 86 moves to a position where the opening of the second portion 82q of the air flow channel 82 is blocked by gravity. In this state, the drug vial 96 is mounted on the vial mounting portion 31. As the drug vial 96 is attached, the distal end portion 76 of the flow path forming unit 70 penetrates the rubber stopper 98, and the air flow path 82 and the communication flow path 81 communicate with the inside of the drug vial 96.

  At this time, the inside of the drug vial 96 and the inside of the solution vial 91 communicate with each other through the communication channel 81. Since the internal pressure of the drug vial 96 is lower than the internal pressure of the solution vial 91, the solution inside the solution vial 91 is brought into the drug vial 96 through the communication channel 81 using this internal pressure difference as a driving force. Inflow.

  At this time, the air flow between the vial mounting portion 31 and the opening portion 51 is regulated by a check valve 86 that closes the opening of the second portion 82q of the air flow channel 82. Thereby, the inside of the medicine vial 96 can be kept airtight, and the driving force due to the internal pressure difference between the vials can contribute to the movement of the solution. Moreover, the air flow between the vial mounting part 21 and the opening part 51 is permitted. As a result, in accordance with the inflow of the solution into the drug vial 96, the air in the external space is caused to flow into the inside of the solution vial 91 through the first portion 82p of the intake channel 52 and the air channel 82. Can do. As a result, the movement of the solution from the solution vial 91 to the drug vial 96 can be smoothly advanced.

  Referring to FIG. 8, the drug solution is then prepared by stirring the solution inside the drug vial 96 and the solid drug. When a cap (not shown) is provided in the intake passage 52, the cap is removed after adjusting the medicine. As a result, outside air having a higher pressure (atmospheric pressure) than the inside of the system is introduced through the intake flow path 52, and it is easy to eliminate the bubbles generated during the adjustment. In particular, it is an effective means for a drug that is difficult to disappear once a solid drug is foamed, such as a protein preparation. Referring to FIG. 9, next, the cap 65 is removed from the luer member 63, and preparations for connecting the syringe are made.

  Referring to FIG. 10, next, the medicine preparation device 10 is turned upside down, and the posture of the medicine preparation device 10 is positioned such that the vial mounting portion 31 is positioned vertically upward and the vial mounting portion 21 is positioned vertically downward. State. The check valve 86 moves to a position where the opening of the first portion 82p of the air flow channel 82 is blocked by gravity. A syringe 67 is connected to the luer member 63.

  Referring to FIG. 11, next, by pulling the plunger of syringe 67, the drug prepared inside drug vial 96 is sucked into syringe 67 through communication channel 81 and drug suction channel 62.

  At this time, the air flow between the vial mounting portion 21 and the opening portion 51 is regulated by a check valve 86 that closes the opening of the first portion 82p of the air flow channel 82. Thereby, it is suppressed that the suction force by the syringe 67 acts on the inside of the solution vial 91. Further, an air flow between the vial mounting part 31 and the opening part 51 is allowed. Thereby, the air in the external space can be caused to flow into the inside of the medicine vial 96 through the second part 82q of the air passage 52 and the air passage 82 with the suction of the medicine into the syringe 67. As a result, the medicine can be smoothly moved from the medicine vial 96 to the syringe 67.

  In the medicine preparation device 10 described above, either one between the vial mounting part 21 and the opening part 51 and between the vial mounting part 31 and the opening part 51 is selected on the path of the air flow path 82. A check valve 86 is provided for shutting off. With such a configuration, in the step shown in FIG. 6, the solution vial 91 is temporarily attached to the vial attachment portion 31, and the drug vial 96 is attached to the vial attachment portion 21 in the step shown in FIG. 7. Even so, the check valve 86 is moved to a predetermined position, and the solution is transferred from the solution vial 91 to the drug vial 96 and the drug is transferred from the drug vial 96 to the syringe 67 appropriately. be able to. That is, in the drug preparation device 10, there is no need to determine the mounting positions of the dissolution liquid vial 91 and the drug vial 96 in advance, and the dissolution liquid vial 91 and the drug vial 96 are attached to the vial mounting unit 21 or the vial mounting unit 31. Regardless of which one is attached, the medicine can be prepared properly and the prepared medicine can be taken out into the syringe 67.

  According to the medicine preparation device 10 according to the embodiment of the present invention configured as described above, the user does not get lost in the mounting position of the vial or mount the vial in the wrong mounting portion. For this reason, the chemical | medical agent preparation instrument which can prepare a chemical | medical agent by a simple usage method is realizable.

  The embodiment disclosed this time should be considered as illustrative in all points and not restrictive. The scope of the present invention is defined by the terms of the claims, rather than the description above, and is intended to include any modifications within the scope and meaning equivalent to the terms of the claims.

It is a side view which shows the chemical | medical agent preparation instrument in embodiment of this invention. It is the figure which looked at the chemical | medical agent preparation instrument in FIG. 1 from the up-down direction. It is sectional drawing which shows the chemical | medical agent preparation instrument in FIG. It is sectional drawing which shows the vial with which the chemical | medical agent preparation instrument in FIG. 1 is mounted | worn. It is sectional drawing which expands and shows the range enclosed with the dashed-two dotted line V in FIG. It is sectional drawing which shows the 1st process of the method of preparing a chemical | medical agent using the chemical | medical agent preparation instrument in FIG. It is sectional drawing which shows the 2nd process of the method of preparing a chemical | medical agent using the chemical | medical agent preparation instrument in FIG. It is sectional drawing which shows the 3rd process of the method of preparing a chemical | medical agent using the chemical | medical agent preparation instrument in FIG. It is sectional drawing which shows the 4th process of the method of preparing a chemical | medical agent using the chemical | medical agent preparation instrument in FIG. It is sectional drawing which shows the 5th process of the method of preparing a chemical | medical agent using the chemical | medical agent preparation instrument in FIG. It is sectional drawing which shows the 6th process of the method of preparing a chemical | medical agent using the chemical | medical agent preparation instrument in FIG. 10 is a cross-sectional view showing a reconstruction device disclosed in Patent Document 1. FIG.

Explanation of symbols

  DESCRIPTION OF SYMBOLS 10 Drug preparation device, 21,31 Vial mounting part, 51 Opening part, 53 Filter, 61 Syringe connection part, 67 Syringe, 70 Flow path formation part, 71,76 Tip part, 81 Communication flow path, 82 Air flow path, 86 valve body, 88 storage space.

Claims (4)

A drug preparation device for preparing a drug by mixing contents arranged in a plurality of vials having an internal pressure difference,
A first vial mounting portion and a second vial mounting portion capable of mounting a vial;
An open portion provided between the first vial mounting portion and the second vial mounting portion and opened to an external space;
The first vial mounting portion and the second vial mounting portion have needle-shaped first tip portions and second tip portions respectively disposed on the first vial mounting portion and the second vial mounting portion, and extend between the first tip portion and the second tip portion. A first channel that communicates with the open portion on the path, and a second channel that extends between the first tip and the second tip independently of the first channel. A flow path forming part to be formed;
A valve that is arranged on the path of the first flow path and selectively shuts off one of the opening part and the first vial mounting part and between the opening part and the second vial mounting part. A drug preparation device comprising a body. A syringe connecting part provided between the first vial mounting part and the second vial mounting part and capable of connecting a syringe;
The said 2nd flow path is a chemical | medical agent preparation instrument of Claim 1 connected to the said syringe connection part on the path | route.   The valve body is movable by gravity between a position where the opening portion and the first vial mounting portion are blocked and a position where the opening portion and the second vial mounting portion are blocked. The drug preparation device according to claim 1 or 2, which is provided in the device. An air filter provided at a position where the opening and the first flow path communicate with each other;
On the path of the first flow path, the valve body is blocked between the opening portion and the first vial mounting portion, and between the opening portion and the second vial mounting portion. A space is formed so as to be movable between and
The medicine preparation device according to any one of claims 1 to 3, wherein the space is partitioned from the open portion by the air filter.

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