JP2010024204A - Skin care preparation - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a transparent or translucent skin care preparation containing a 4-alkylresorcinol, having low viscosity, excellent usability (no greasiness, no sliminess, light spread, no oiliness and good compatibility with the skin) and stability. <P>SOLUTION: The transparent or translucent skin care preparation comprises (a) an alkylresorcinol or its salt (e.g. 4-isobutylresorcinol or its salt), (b) an oil and (c) one or more kinds selected from an amphoteric surfactant, a cationic surfactant and a cationic polymer. <P>COPYRIGHT: (C)2010,JPO&INPIT

Description

  The present invention relates to a transparent or translucent skin external preparation. More specifically, it contains 4-alkylresorcinol, has a low viscosity, is easy to use (no stickiness, no slime, lightly spreads, not oily, has good skin fit), and has excellent stability and translucency. The present invention relates to a skin external preparation.

  In order to solubilize a system containing a poorly water-soluble component in water to obtain a transparent or translucent solubilized composition, a nonionic surfactant is usually used. Nonionic surfactants are known to be excellent in the function of transparently solubilizing oil-soluble components, and further studies have been made on enhancing solubilizing ability in combination with other components (for example, Patent Documents 1 to 3). 2). However, resorcinol derivatives that have an intermediate polarity and are poorly water-soluble are very difficult to solubilize transparently or translucently even if a nonionic surfactant is used.

  On the other hand, a polymer (for example, acrylic acid / methacrylic acid) that contains a resorcinol derivative, does not use a nonionic surfactant, and has an average molecular weight of 1 to 3 million having an alkyl group having 10 to 30 carbon atoms as a side chain. An emulsified composition using an alkyl copolymer or the like has been proposed (see Patent Document 3). This technique is obtained by stabilizing a resorcinol derivative as an emulsion, is an opaque and highly viscous composition, and cannot achieve a refreshing and fresh feeling without stickiness.

  Therefore, even with the prior art as described above, it was not possible to solubilize the resorcinol derivative to obtain a clear or translucent low viscosity lotion or lotion.

JP 2000-7484 A JP 2002-87933 A JP 2001-10925 A

  The present invention is an external preparation for skin containing 4-alkylresorcinol, having low viscosity, usability (no stickiness, no sliminess, light stretch, not oily, good skin fit) and stability An object of the present invention is to provide a transparent or translucent skin external preparation excellent in skin resistance.

  In order to solve the above problems, the present invention provides (a) 4-alkylresorcinol or a salt thereof represented by the following formula (I), (b) an oil component, and (c) an amphoteric surfactant, a cationic surfactant, And a transparent or translucent external preparation for skin containing at least one selected from cationic polymers.

(In formula (I), R ₁ represents a linear or branched alkyl group having 2 to 12 carbon atoms.)
Moreover, this invention is 0.001-20 mass% of (a) component with respect to skin external preparation whole quantity, 0.001-3 mass% of (b) component, and 0.01-2 mass of (c) component. % Of the above-mentioned transparent to translucent skin external preparation.

  Moreover, this invention provides the said transparent thru | or translucent skin external preparation whose (a) component is 4-isobutyl resorcinol or its salt.

  According to the present invention, an external preparation for skin containing 4-alkylresorcinol, having low viscosity, usability (no stickiness, no sliminess, light stretch, not oily, good skin conformance) and stability A translucent or translucent skin preparation for skin that excels in skin resistance is provided.

  Hereinafter, the present invention will be described in detail.

  The 4-alkylresorcinol or a salt thereof as the component (a) used in the present invention is a compound represented by the following formula (I) or a salt thereof.

In the formula (I), R ₁ represents a linear or branched alkyl group having 2 to 12 carbon atoms. Examples of the linear alkyl group include an ethyl group, a propyl group, a butyl group, a pentyl group, a hexyl group, a heptyl group, an octyl group, a nonyl group, a decyl group, an undecyl group, and a dodecyl group. Preferred examples of the branched alkyl group include those in which a hydrogen atom in a linear alkyl group is substituted with a lower alkyl group such as a methyl group, specifically, an isopropyl group, an isobutyl group, a tert group. -A butyl group, an isoamyl group, 2-methylhexyl group etc. are mentioned. In the present invention, from the viewpoints of physiological activity and cytotoxicity, R ₁ is preferably an ethyl group, a butyl group, an isobutyl group, an isopropyl group, a propyl group, a tert-butyl group or the like, and most preferably an isobutyl group.

  The salt of alkylresorcinol represented by the above formula (I) is not particularly limited. For example, alkali metal salts such as sodium salt, potassium salt and lithium salt, alkaline earth metal salts such as magnesium salt and calcium salt In addition, ammonium salts, amino acid salts and the like can be mentioned. However, it is not limited to these examples. These salts can be readily prepared by conventional methods, for example, treating the corresponding acidic compound with an aqueous solution containing the desired pharmacologically acceptable cation, followed by evaporation of the resulting solution. It can be easily prepared by drying (preferably under reduced pressure). Alternatively, these salts can be prepared by mixing together a lower alcohol solution of an acidic compound and the desired metal alkoxide and then evaporating the resulting solution to dryness in the same manner as described above. it can. In either case, it is preferred to use reagents in stoichiometric amounts to ensure completion of the reaction and maximum yield of the desired end product.

  The component (a) used in the present invention has a melanin production inhibitory action and an antibacterial action, and is contained in cosmetics for the purpose of whitening in particular. Therefore, the component (a) is useful as a whitening agent and is suitably blended into a skin whitening external preparation. Furthermore, since the cytotoxicity is very low, the blending amount can be set high. (A) A component can use 1 type (s) or 2 or more types.

  (A) As for the compounding quantity of a component, 0.001-20 mass% is preferable in this invention skin external preparation, More preferably, it is 0.01-10 mass%. If the blending amount is less than 0.001% by mass, sufficient whitening effect, antibacterial effect and the like are not exhibited. On the other hand, even if the blending amount exceeds 20% by mass, improvement in the effect commensurate with the increase is not recognized.

  As the oil component (b) used in the present invention, both polar and non-polar oil components commonly used in cosmetics can be used. For example, natural animal and plant oils and fats (liquid oils and solid oils), waxes, hydrocarbons Examples include oils, higher fatty acids, higher alcohols, synthetic ester oils, synthetic ether oils, and silicone oils.

  Examples of liquid fats and oils in natural animal and vegetable oils include lavender oil, orange oil, mint oil, evening primrose oil, avocado oil, camellia oil, turtle oil, macadamia nut oil, corn oil, mink oil, olive oil, jojoba oil, rapeseed oil , Egg yolk oil, sesame oil, persic oil, wheat germ oil, sasanqua oil, castor oil, flaxseed oil, safflower oil, cottonseed oil, eno oil, soybean oil, peanut oil, tea seed oil, kaya oil, rice bran oil, cinnagiri oil, Japanese kiri oil, jojoba oil, germ oil, triglycerin and the like can be mentioned. Oils blended as so-called “perfumes” are also included here. Examples of the solid fat include cacao butter, palm oil, horse fat, hydrogenated palm oil, palm oil, beef tallow, sheep fat, hydrogenated beef tallow, palm kernel oil, pork fat, beef bone fat, owl kernel oil, hydrogenated oil, Examples include beef leg fat, mole, and hardened castor oil.

  Examples of waxes include beeswax, candelilla wax, cotton wax, carnauba wax, bayberry wax, ibota wax, whale wax, montan wax, nuka wax, lanolin, kapok wax, lanolin acetate, liquid lanolin, sugar cane wax, lanolin fatty acid isopropyl, hexyl laurate, and reduced lanolin. Jojoba wax, hard lanolin, shellac wax, POE lanolin alcohol ether, POE lanolin alcohol acetate, POE cholesterol ether, lanolin fatty acid polyethylene glycol, POE hydrogenated lanolin alcohol ether, and the like.

  Examples of the hydrocarbon oil include liquid paraffin, ozokerite, squalane, pristane, paraffin, ceresin, squalene, petrolatum, microcrystalline wax, and the like.

  Examples of the higher fatty acid include lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, oleic acid, undecylenic acid, toluic acid, isostearic acid, linoleic acid, linolenic acid, eicosapentaenoic acid (EPA), docosahexaenoic acid ( DHA) and the like.

  Examples of higher alcohols include linear alcohols (eg, lauryl alcohol, cetyl alcohol, stearyl alcohol, behenyl alcohol, myristyl alcohol, oleyl alcohol, cetostearyl alcohol); branched chain alcohols (eg, monostearyl glycerin ether (batyl alcohol) ), 2-decyltetradecinol, lanolin alcohol, cholesterol, phytosterol, hexyldodecanol, isostearyl alcohol, octyldodecanol and the like.

  Synthetic ester oils include, for example, esters of linear higher fatty acids and lower alcohols such as isopropyl myristate, butyl myristate, isopropyl palmitate, ethyl stearate, butyl stearate, ethyl oleate, ethyl linoleate; caprylic acid Esters of linear higher fatty acids and linear higher alcohols such as cetyl, hexyl rallate, decyl myristate, myristyl myristate, cetyl palmitate, stearyl stearate, decyl oleate, cetyl ricinoleate; isostearyl laurate, myristine Isotridecyl acid, isocetyl myristate, isostearyl myristate, octyldodecyl myristate, octyl palmitate, isocetyl palmitate, isostearyl palmitate, stearic acid Esters of linear fatty acids such as cetyl, isodecyl oleate, octyldodecyl oleate and branched alcohols; esters of branched fatty acids such as ethyl isostearate and isopropyl isostearate; lower alcohols; cetyl octoate, cetostearyl octoate , Esters of branched fatty acids such as stearyl octoate and hexyl isostearate with linear higher alcohols; ethylene glycol dioctanoate, ethylene glycol dioleate, propylene glycol dicaprylate, propylene glycol dicaprate, propylene glycol dioleate, neocapric dicaprate Esters of fatty acids such as pentyl glycol and triethylhexanoin with polyhydric alcohols; octyldodecyl neopentanoate, isocetyl octoate, ethyl octoate Esters of branched and branched alcohols such as stearyl, octyl isopelargonate, octyldodecyl neodecanoate, isostearyl isostearate; lauryl lactate, myristyl lactate, cetyl lactate, triethyl citrate, trioctyl citrate, triisocetyl citrate, Examples thereof include esters of hydroxycarboxylic acids such as diisostearyl malate; esters of dibasic acids such as dioctyl succinate and dioctyl sebacate.

  Synthetic ether oils include diethylene glycol monopropyl ether, polyoxyethylene polyoxypropylene pentaerythritol ether, polyoxypropylene butyl ether, and the like.

  Examples of the silicone oil include linear polysiloxanes (for example, dimethylpolysiloxane, methylphenylpolysiloxane, diphenylpolysiloxane, etc.); cyclic polysiloxanes (for example, octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, dodecamethylcyclohexyl). And silicone resins that form a three-dimensional network structure, various modified polysiloxanes (amino-modified polysiloxane, polyether-modified polysiloxane, alkyl-modified polysiloxane, fluorine-modified polysiloxane, etc.) It is done.

  (B) As for the compounding quantity of a component, 0.001-3 mass% is preferable in this invention skin external preparation, More preferably, it is 0.001-1 mass%. If the blending amount is less than 0.001% by mass, the effect of oil blending cannot be expected. On the other hand, if the blending amount exceeds 3% by mass, it becomes difficult to keep the system stable. (B) A component can use 1 type (s) or 2 or more types.

  Component (c) is one or more of amphoteric surfactants, cationic surfactants, and cationic polymers.

  Examples of amphoteric surfactants include 2-undecyl-N, N, N- (hydroxyethylcarboxymethyl) -2-imidazoline sodium, 2-cocoyl-2-imidazolinium hydroxide-1-carboxyethyloxy disodium. Imidazoline-based amphoteric surfactants such as salts; 2-heptadecyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, lauryldimethylaminoacetic acid betaine, alkylbetaine, amidopropyl betaine fatty acid derivatives (for example, coconut oil fatty acid amidopropyl Betaine), and betaine surfactants such as aminopropyl betaine fatty acid derivatives. Of these, betaine amphoteric surfactants are preferably used.

  Examples of the cationic surfactant include alkyltrimethylammonium salts such as stearyltrimethylammonium chloride and lauryltrimethylammonium chloride; alkylpyridinium salts such as cetylpyridinium chloride; dialkyldimethylammonium salts such as distearyldimethylammonium chloride; poly (N , N′-dimethyl-3,5-methylenepiperidinium); alkyl quaternary ammonium salts; alkyl dimethyl benzyl ammonium salts; alkyl isoquinolinium salts; dialkyl morpholinium salts; POE-alkyl amines; Polyamine fatty acid derivatives; POE-amine fatty acid derivatives; polyamine fatty acid derivatives amyl alcohol fatty acid derivatives; benzalkonium chloride; benzethonium chloride. Of these, alkyltrimethylammonium salts and POE-amine fatty acid derivatives are preferably used.

  Examples of the cationic polymer include dimethyldiallylammonium chloride / acrylamide copolymer, β-N-N-dimethyl-N-ethylammonioethyl vinylpyrrolidone chloride copolymer of acrylic acid, and the like. Of these, dimethyldiallylammonium chloride / acrylamide copolymer is preferably used.

  In the present invention, one or more of amphoteric surfactants, cationic surfactants, and cationic polymers can be used. In the present invention, a cationic surfactant or a cationic polymer can be used for enhancing transparency, and an amphoteric surfactant can be used for preparing a translucent base. However, it is needless to say that the present invention is not limited to this.

  The blending amount of the component (c) in the external preparation for skin of the present invention is 0.01 to 2% by mass, preferably 0.1 to 0.5% by mass, based on the total amount of the external preparation for skin. If it is less than 0.01% by mass, it is difficult to make the system transparent or translucent. On the other hand, if it exceeds 2% by mass, it is not preferable in terms of usability (increase in stickiness) and irritation.

  In the present invention, the components (a) to (c) are blended as essential components, so that the component (a), which is a poorly water-soluble component, is solubilized in an aqueous component such as water or a lower alcohol to be transparent or semi-transparent. It can be made into a transparent base, and has low viscosity and excellent usability and stability. Examples of the aqueous component include water, lower alcohols (ethanol and the like), moisturizing components and the like. However, it is not limited to these examples.

  In the present invention, “transparent to translucent” means that the L value, which is an index of transparency, is generally 60 or more, preferably 70 or more. In the present invention, the “L value” can be measured with a color difference meter (GretagMacbeth Color-Eye 7000A) or the like. The closer the L value is to 100, the higher the transparency.

  In addition to the essential components described above, the external preparation for skin of the present invention, in the range not impairing the effects of the present invention, are usually used for other external preparations for skin, such as cosmetics and pharmaceuticals, such as wetting agents, UV protection Agent, antioxidant, sequestering agent, surfactant (other than component (c)), preservative, moisturizer, fragrance, water, alcohol, thickener, powder, coloring material, herbal medicine, various other medicinal ingredients, etc. Can be appropriately blended as necessary. Furthermore, other whitening agents such as vitamin C, magnesium ascorbate phosphate, glucoside ascorbate, arbutin, kojic acid, tranexamic acid, and potassium 4-methoxysalicylate can be appropriately blended.

  The external preparation for skin of the present invention is widely applicable in the fields of cosmetics, pharmaceuticals, and quasi drugs. The dosage form is not particularly limited as long as it can be applied to the skin, but is preferably a low-viscosity liquid skin external preparation such as lotion, lotion, impregnation liquid impregnated into a sheet base, or gel. In the present invention, the low viscosity means a viscosity of about 100 to 4,000 (mPa · s / 30 ° C., B-type viscometer) or less.

  In addition, although the skin external preparation of this invention can be accommodated in arbitrary containers, a highly transparent thing is preferable. Moreover, the light stability with respect to (a) component can be improved by accommodating in what is called a UV cut container. A UV cut container is usually manufactured by a method of blending a so-called UV cut agent such as an ultraviolet absorber with a material such as glass or plastic resin, or coating the surface of such a material, but is limited to these examples. It is not something.

  Hereinafter, the present invention will be described more specifically with reference to examples. However, the present invention is not limited thereto. Unless otherwise specified, the blending amount is expressed in mass% with respect to the system in which the component is blended. The following composition is a cosmetic base.

[L value, appearance (stability)]
The test sample was housed in a transparent glass container, and the appearance (presence / absence of a separated product, stability) was determined by visual judgment, and the transparency was determined by the L value.

<L value>:
The L value (lightness) was measured with a color difference meter (GretagMacbeth Color-Eye 7000A). The closer the L value is to 100, the higher the brightness.

<Appearance evaluation (stability evaluation)>:
○: Almost no separation is observed, and it is translucent or transparent. Δ: Some separation is observed. X: Separation is observed.

[Usability (no stickiness)]
A use panel test was conducted with 10 specialist panels, and the following evaluation criteria were used.
(Evaluation)
○: 5 or more people out of 10 evaluated as non-sticky Δ: 3 out of 10 people evaluated as non-sticky ×: 2 out of 10 people evaluated as non-sticky

[Usability (no sliminess)]
A use panel test was conducted with 10 specialist panels, and the following evaluation criteria were used.
(Evaluation)
○: 5 or more people out of 10 evaluated that there was no slimming Δ: 3 out of 10 people evaluated that there was no slimming ×: 2 out of 10 people evaluated that there was no slimming

[Usability (lightness of spread)]
A use panel test was conducted with 10 specialist panels, and the following evaluation criteria were used.
(Evaluation)
○: 5 or more people out of 10 people evaluated that the spread is light Δ: 3 to 4 people out of 10 people evaluated that the spread was light ×: 2 out of 10 people evaluated that the spread was light

[Usability (oiliness)]
A use panel test was conducted with 10 specialist panels, and the following evaluation criteria were used.
(Evaluation)
○: 5 out of 10 people are evaluated as not oily Δ: 3 out of 10 people are evaluated as not oily ×: 2 out of 10 people are not oily And evaluation

[Usability (skin familiarity)]
A use panel test was conducted with 10 specialist panels, and the following evaluation criteria were used.
(Evaluation)
○: Out of 10 people, 5 or more people evaluated that skin familiarity is good. Δ: Out of 10 people, 3-4 people evaluated that skin familiarity was good. ×: Out of 10 people, 2 or less people were familiar with skin. And evaluation

(Comparative Examples 1-3)
Comparative Examples 1 to 3 shown in Table 1 below are compositions containing a small amount of the component (a) and the component (b) and no surfactant. About these compositions, when L value and external appearance (stability) were evaluated by the said evaluation method, the external appearance was opaque and the isolation | separation thing was recognized. In addition, since the isolate was recognized in the composition, usability evaluation could not be performed.

(Comparative Examples 4 to 9)
Comparative Examples 4 to 9 shown in the following Table 2 are compositions containing the component (a), the component (b), and the nonionic surfactant (no blending of the component (c)). These compositions were evaluated for L value, appearance (stability), and usability (no stickiness, no sliminess, lightness of spread, oiliness, skin familiarity) by the above evaluation methods. The results are shown in Table 2.

  As is clear from the results shown in Table 2, none of Comparative Examples 4 to 9 could achieve the effects of the present invention. In Comparative Examples 6 and 9 having a small amount (0.2% by mass) of the nonionic surfactant, a separated product was observed in the composition, and the usability could not be evaluated. As the compounding amount of the nonionic surfactant was increased, the L value increased, but the usability was inferior (Comparative Examples 5 and 8, Comparative Examples 4 and 7).

(Examples 1-5)
The compositions shown in Table 3 below were evaluated for L value, appearance (stability), and usability (no stickiness, no sliminess, lightness of spread, oiliness, skin familiarity) by the above evaluation methods. The results are shown in Table 3.

  As is apparent from the results shown in Table 3, in Examples 1 to 7, the appearance was transparent to translucent, no separation was observed, the stability was excellent, and the usability was also excellent.

  From the results of Tables 1 to 3, it can be seen that a combination of the components (a) to (c) can provide a transparent or translucent solution with excellent usability and stability.

  Further formulation examples are shown below.

(Example 6: lotion)
(Mixed component) (mass%)
(1) Ethyl alcohol 5.0
(2) Glycerin 1.0
(3) 1,3-butylene glycol 5.0
(4) POE / POP decyl tetradecyl ether 0.2
(5) Sodium hexametaphosphate 0.03
(6) Sodium polyaspartate 0.1
(7) 3-O-ethyl-L-ascorbic acid 5.0
(8) 4-isobutylresorcinol 0.1
(9) Green tea extract 0.1
(10) Hypericum extract 0.1
(11) Western mint extract 0.1
(12) α-Glucosyl hesperidin 0.01
(13) Iris root extract 0.1
(14) EDTA3 sodium 0.1
(15) 2-N-carboxymethyl-N-
Hydroxyethylimidazolinium betaine 1.0
(16) Carboxyvinyl polymer 0.05
(17) Sodium acrylate / 2-acrylamido-2-methyl
Propanesulfonic acid copolymer 0.05
(18) Potassium hydroxide 0.02
(19) Phenoxyethanol appropriate amount (20) Purified water Residue (21) Fragrance 0.05

(Example 7: lotion)
(Mixed component) (mass%)
(1) Ethanol 10.0
(2) Glycerin 2.0
(3) Dipropylene glycol 1.0
(4) Isostearic acid 0.1
(5) POE / POP methylpolysiloxane copolymer 1.0
(6) Lauryldimethylaminoacetic acid betaine 0.2
(7) Citric acid 0.01
(8) Sodium citrate 0.09
(9) Sodium hexametaphosphate 0.01
(10) Chamomile extract 0.1
(11) Ogon Extract 0.1
(12) Izayoi Rose 0.1
(13) 2-O-ethyl-L-ascorbic acid 0.01
(14) 4-n-butylresorcinol 0.01
(15) Polysorbate 60 7.0
(16) Lavender oil 0.001
(17) Appropriate amount of phenoxyethanol (18) Active hydrogen water 1.0
(19) Purified water residue

(Example 8: lotion)
(Mixed component) (mass%)
(1) Ethanol 10.0
(2) Glycerin 2.0
(3) Dipropylene glycol 1.0
(4) Isostearic acid 0.1
(5) POE / POP methylpolysiloxane copolymer 1.0
(6) Dimethyldiallylammonium chloride / acrylamide copolymer 0.1
(7) Citric acid 0.01
(8) Sodium citrate 0.09
(9) Sodium hexametaphosphate 0.01
(10) Chamomile extract 0.1
(11) Isaiyo Barakajitsu Extract 0.1
(12) Ogon Extract 0.1
(13) Ascorbic acid-2-glucoside 1.0
(14) 4-Butylresorcinol 1.0
(15) POE (30) Cholestanol 1.0
(16) Lavender oil 0.001
(17) Appropriate amount of phenoxyethanol (18) Active hydrogen water 1.0
(19) Purified water residue

(Example 9: lotion)
(Mixed component) (mass%)
(1) Ethanol 10.0
(2) Glycerin 2.0
(3) Dipropylene glycol 1.0
(4) Isostearic acid 0.1
(5) POE / POP methylpolysiloxane copolymer 1.0
(6) Lauryldimethylaminoacetic acid betaine 0.1
(7) Citric acid 0.09
(8) Sodium citrate 0.01
(9) Stearyltrimethylammonium chloride 0.01
(10) Giant extract 0.1
(11) Chamomile extract 0.1
(12) Ogon Extract 0.1
(13) 3-O-ethyl-L-ascorbic acid 1.0
(14) 4-propylresorcinol 0.1
(15) POE · POP glycol-mono-DL-α-tocopherol 0.01
(16) Lavender oil 0.001
(17) Appropriate amount of phenoxyethanol (18) Active hydrogen water 1.0
(19) Purified water residue

(Example 10: lotion)
(Mixed component) (mass%)
(1) Ethyl alcohol 5.0
(2) Glycerin 1.0
(3) 1,3-butylene glycol 5.0
(4) POE / POP decyl tetradecyl ether 0.2
(5) Sodium hexametaphosphate 0.03
(6) Sodium polyaspartate 0.1
(7) 3-O-ethyl-L-ascorbic acid 5.0
(8) 4-ethylresorcinol 0.01
(9) Green tea extract 0.1
(10) Button pi extract 0.1
(11) Western mint extract 0.1
(12) α-Glucosyl hesperidin 0.01
(13) Iris root extract 0.1
(14) EDTA3 sodium 0.1
(15) Polysorbate 60 1.0
(16) POE (10) stearylamine 0.05
(17) Sodium acrylate / 2-acrylamido-2-methyl
Propanesulfonic acid copolymer 0.05
(18) Potassium hydroxide 0.02
(19) Phenoxyethanol appropriate amount (20) Purified water Residue (21) Fragrance 0.01

(Example 11: lotion)
(Mixed component) (mass%)
(1) Ethyl alcohol 5.0
(2) Glycerin 1.0
(3) 1,3-butylene glycol 5.0
(4) POE / POP decyl tetradecyl ether 0.2
(5) Sodium hexametaphosphate 0.03
(6) Sodium polyaspartate 0.1
(7) 3-O-ethyl-L-ascorbic acid 0.01
(8) 4-isobutylresorcinol 1.0
(9) Green tea extract 0.1
(10) Yukinoshita extract 0.1
(11) Western mint extract 0.1
(12) α-Glucosyl hesperidin 0.01
(13) Iris root extract 0.1
(14) EDTA3 sodium 0.1
(15) 2-N-carboxymethyl-N-hydroxyethyl
Imidazolinium betaine 3.0
(16) Carboxyvinyl polymer 0.05
(17) Dimethylacrylamide / 2-acrylamido-2-methyl
Propanesulfonic acid copolymer 0.05
(18) Potassium hydroxide 0.02
(19) Phenoxyethanol appropriate amount (20) Purified water Residue (21) Fragrance 0.02

  INDUSTRIAL APPLICABILITY The present invention is a skin external preparation that is transparent to translucent, has a low viscosity, and has a good feeling of use. In particular, it can be effectively used as a skin external preparation containing active ingredients such as cosmetics, quasi drugs, and pharmaceuticals.

Claims (3)

(A) 4-alkylresorcinol represented by the following formula (I) or a salt thereof, (b) an oil component, and (c) an amphoteric surfactant, a cationic surfactant, and a cationic polymer A transparent or translucent skin external preparation containing two or more kinds.

(In formula (I), R ₁ represents a linear or branched alkyl group having 2 to 12 carbon atoms.)   0.001 to 20% by mass of component (a), 0.001 to 3% by mass of component (b), and 0.01 to 2% by mass of component (c) with respect to the total amount of the external preparation for skin, The transparent or translucent external preparation for skin according to claim 1.   The transparent or translucent external preparation for skin according to claim 1 or 2, wherein the component (a) is 4-isobutylresorcinol or a salt thereof.