JP2009540319A - 質量分析バイオマーカーアッセイ - Google Patents

質量分析バイオマーカーアッセイ Download PDF

Info

Publication number
JP2009540319A
JP2009540319A JP2009514893A JP2009514893A JP2009540319A JP 2009540319 A JP2009540319 A JP 2009540319A JP 2009514893 A JP2009514893 A JP 2009514893A JP 2009514893 A JP2009514893 A JP 2009514893A JP 2009540319 A JP2009540319 A JP 2009540319A
Authority
JP
Japan
Prior art keywords
biomarker
mass
signal
sample
msba
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2009514893A
Other languages
English (en)
Japanese (ja)
Inventor
俊秀 西村
淳 荻原
猛 川村
隆雄 川上
完 京野
光洋 金澤
ニーベリ，フレドリク
マルコ−ヴァルガ，ジェルジ
久栄 安養寺
Original Assignee
アストラゼネカ ユーケー リミテッド
株式会社メディカル・プロテオスコープ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アストラゼネカ ユーケー リミテッド, 株式会社メディカル・プロテオスコープ filed Critical アストラゼネカ ユーケー リミテッド
Publication of JP2009540319A publication Critical patent/JP2009540319A/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/74—Optical detectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
JP2009514893A 2006-06-13 2007-06-13 質量分析バイオマーカーアッセイ Pending JP2009540319A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0611669.3A GB0611669D0 (en) 2006-06-13 2006-06-13 Mass spectrometry biomarker assay
PCT/GB2007/002187 WO2007144606A2 (en) 2006-06-13 2007-06-13 Mass spectrometry biomarker assay

Publications (1)

Publication Number Publication Date
JP2009540319A true JP2009540319A (ja) 2009-11-19

Family

ID=36745797

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009514893A Pending JP2009540319A (ja) 2006-06-13 2007-06-13 質量分析バイオマーカーアッセイ

Country Status (10)

Country Link
EP (1) EP2035829A2 (es)
JP (1) JP2009540319A (es)
KR (1) KR20090068199A (es)
CN (1) CN101611313A (es)
AU (1) AU2007258970A1 (es)
BR (1) BRPI0711967A2 (es)
CA (1) CA2651934A1 (es)
GB (1) GB0611669D0 (es)
MX (1) MX2008015158A (es)
WO (1) WO2007144606A2 (es)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013515965A (ja) * 2009-12-29 2013-05-09 コリア ベーシック サイエンス インスティテュート 高分解能質量分析法と薬理活性検査を利用した天然物の薬理活性物質発掘方法
JP2013525759A (ja) * 2010-04-16 2013-06-20 イマティクス バイオテクノロジーズ ゲーエムベーハー がん、自己免疫および感染症の免疫療法開発用自然処理ｈｌａ制限ペプチドの特異的定量方法
JP2017504333A (ja) * 2014-01-17 2017-02-09 ブルーカー ダルトニック ゲーエムベーハー 代謝測定によるマススペクトル耐性判定
JP2017509945A (ja) * 2014-01-10 2017-04-06 イマビオテクＩｍａｂｉｏｔｅｃｈ 分子イメージングデータを処理する方法及び対応するデータサーバ
WO2017142025A1 (ja) * 2016-02-19 2017-08-24 国立大学法人宮崎大学 腺癌の検出方法
JP2019518213A (ja) * 2016-05-24 2019-06-27 イン オーヴォ ベスローデン フエンノートシャップ 家禽性別を非破壊卵内決定するための方法およびシステム
JP2020526747A (ja) * 2017-06-29 2020-08-31 クワンティシジョン ディアグノスティックス インク 固形腫瘍の診断用のバイオマーカーの絶対定量の方法および装置

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011528790A (ja) * 2008-07-23 2011-11-24 ピー デバイシズ インコーポレーテッド プラズマを利用する携帯型診断装置及び診断方法
GB0906698D0 (en) 2009-04-17 2009-06-03 Queen Mary & Westfield College Method for quantifying modified peptides
US9141756B1 (en) 2010-07-20 2015-09-22 University Of Southern California Multi-scale complex systems transdisciplinary analysis of response to therapy
CN102201039A (zh) * 2010-08-19 2011-09-28 上海聚类生物科技有限公司 一种分析ltq数据的方法
GB201204278D0 (en) 2012-03-09 2012-04-25 Queen Mary & Westfield College Method
GB201509313D0 (en) * 2015-05-29 2015-07-15 Micromass Ltd Sample mass spectrum analysis
MA44511A (fr) * 2016-03-31 2019-02-06 Discerndx Inc Génération et utilisation de bases de données de biomarqueurs
AU2017314217A1 (en) * 2016-08-19 2019-03-28 Monash University Spectroscopic systems and methods for the identification and quantification of pathogens
US9905405B1 (en) * 2017-02-13 2018-02-27 Thermo Finnigan Llc Method of generating an inclusion list for targeted mass spectrometric analysis
MY202410A (en) 2017-09-01 2024-04-27 Venn Biosciences Corp Identification and use of glycopeptides as biomarkers for diagnosis and treatment monitoring
CN111316106A (zh) * 2017-09-05 2020-06-19 迪森德克斯公司 自动化样品工作流程门控和数据分析
GB2569805B (en) * 2017-12-22 2023-03-08 Asymptote Ltd Method and system relating to cooling conditions for a biological sample
EP3794548B1 (en) * 2018-05-15 2024-06-26 Ventana Medical Systems, Inc. Quantitation of signal in stain aggregates
CN111672658B (zh) * 2020-06-08 2022-05-13 惠州市新泓威科技有限公司 电子雾化设备最佳雾化温度的检测与控制方法及其电子雾化设备
EP4047371A1 (en) * 2021-02-18 2022-08-24 Thermo Fisher Scientific (Bremen) GmbH Method and apparatus for analysing samples of biomolecules using mass spectrometry with data-independent acquisition
KR102632163B1 (ko) 2022-04-13 2024-02-01 오보젠 주식회사 가금류 알(卵)의 암수 검사 및 선별장치 그리고 이를 이용한 선별방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004061410A2 (en) * 2002-12-18 2004-07-22 Ciphergen Biosystems, Inc. Serum biomarkers in lung cancer
DE10324149A1 (de) * 2003-05-26 2004-12-16 Imat-Uve Gmbh Verfahren und Vorrichtung zur GC/MS- oder LC/MS-Screeninganalyse
AU2005231101A1 (en) * 2004-03-30 2005-10-20 Eastern Virginia Medical School Lung cancer biomarkers
GB2430794B (en) * 2004-05-20 2009-10-21 Waters Investments Ltd Method and apparatus for identifying proteins in mixtures

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013515965A (ja) * 2009-12-29 2013-05-09 コリア ベーシック サイエンス インスティテュート 高分解能質量分析法と薬理活性検査を利用した天然物の薬理活性物質発掘方法
JP2013525759A (ja) * 2010-04-16 2013-06-20 イマティクス バイオテクノロジーズ ゲーエムベーハー がん、自己免疫および感染症の免疫療法開発用自然処理ｈｌａ制限ペプチドの特異的定量方法
JP2017509945A (ja) * 2014-01-10 2017-04-06 イマビオテクＩｍａｂｉｏｔｅｃｈ 分子イメージングデータを処理する方法及び対応するデータサーバ
JP2017504333A (ja) * 2014-01-17 2017-02-09 ブルーカー ダルトニック ゲーエムベーハー 代謝測定によるマススペクトル耐性判定
US11142784B2 (en) 2014-01-17 2021-10-12 Bruker Daltonik Gmbh Mass spectrometric resistance determination by measuring metabolism
WO2017142025A1 (ja) * 2016-02-19 2017-08-24 国立大学法人宮崎大学 腺癌の検出方法
JPWO2017142025A1 (ja) * 2016-02-19 2018-12-27 国立大学法人 宮崎大学 腺癌の検出方法
JP2019518213A (ja) * 2016-05-24 2019-06-27 イン オーヴォ ベスローデン フエンノートシャップ 家禽性別を非破壊卵内決定するための方法およびシステム
US11686732B2 (en) 2016-05-24 2023-06-27 In Ovo Holding B.V. Method and system for the non-destructive in ovo determination of fowl gender
JP7320353B2 (ja) 2016-05-24 2023-08-03 イン オーヴォ ホールディング ベスローデン フエンノートシャップ 家禽性別を非破壊卵内決定するための方法およびシステム
JP2020526747A (ja) * 2017-06-29 2020-08-31 クワンティシジョン ディアグノスティックス インク 固形腫瘍の診断用のバイオマーカーの絶対定量の方法および装置
JP7194128B2 (ja) 2017-06-29 2022-12-21 イェンタイ クワンティシジョン ディアグノスティックス インク 固形腫瘍の診断用のバイオマーカーの絶対定量の方法および装置

Also Published As

Publication number Publication date
EP2035829A2 (en) 2009-03-18
CA2651934A1 (en) 2007-12-21
BRPI0711967A2 (pt) 2012-01-24
CN101611313A (zh) 2009-12-23
MX2008015158A (es) 2009-04-30
AU2007258970A1 (en) 2007-12-21
WO2007144606A3 (en) 2008-04-03
KR20090068199A (ko) 2009-06-25
GB0611669D0 (en) 2006-07-19
WO2007144606A2 (en) 2007-12-21

Similar Documents

Publication Publication Date Title
JP2009540319A (ja) 質量分析バイオマーカーアッセイ
US20060031023A1 (en) Mass intensity profiling system and uses thereof
Issaq et al. Peer reviewed: SELDI-TOF MS for diagnostic proteomics
Hirsch et al. Proteomics: current techniques and potential applications to lung disease
US7485852B2 (en) Mass analysis method and mass analysis apparatus
JP4672614B2 (ja) 迅速かつ定量的なプロテオーム解析および関連した方法
US20060269945A1 (en) Constellation mapping and uses thereof
US20060287834A1 (en) Virtual mass spectrometry
Sokolowska et al. Applications of mass spectrometry in proteomics
CN112305121B (zh) 代谢标志物在动脉粥样硬化性脑梗死中的应用
Woods et al. Mass spectrometry for proteomics-based investigation
An et al. A glycomics approach to the discovery of potential cancer biomarkers
US8012692B2 (en) Elastin peptide fingerprints and analysis methods for MMP12 related to COPD
EP1887351A1 (en) Screening method for specific protein in proteome comprehensive analysis
Xu et al. Analysis of biofluids for biomarker research
CN112630344B (zh) 代谢标志物在脑梗死中的用途
Vaezzadeh et al. Proteomics and opportunities for clinical translation in urological disease
RU2673551C2 (ru) Протеотипический пептид q9y4w6-02 и способ масс-спектрометрического анализа содержания afg3-подобного белка человека на его основе
Henry et al. Introduction to sample preparation for proteomics and mass spectrometry
Reisdorph et al. Proteomics methods and applications for the practicing clinician
Petrák Proteomics and its role in medicine
US20100203565A1 (en) Peptide Fingerprint from the Degradation of Elastin by HNE
ÜNAL Mass Spectrometry in Clinical Diagnosis: Cancer Biomarkers
AU2002363690A1 (en) Mass intensity profiling system and uses thereof
Conrads et al. Mass Spectrometry‐Based Proteomic Approaches for Disease Diagnosis and Biomarker Discovery