JP2009537507A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009537507A5 JP2009537507A5 JP2009510567A JP2009510567A JP2009537507A5 JP 2009537507 A5 JP2009537507 A5 JP 2009537507A5 JP 2009510567 A JP2009510567 A JP 2009510567A JP 2009510567 A JP2009510567 A JP 2009510567A JP 2009537507 A5 JP2009537507 A5 JP 2009537507A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- mammal
- atherosclerosis
- disease
- related disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 241000124008 Mammalia Species 0.000 claims description 18
- 201000001320 Atherosclerosis Diseases 0.000 claims description 15
- 239000002671 adjuvant Substances 0.000 claims description 6
- 239000003814 drug Substances 0.000 claims description 5
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims description 3
- 239000002245 particle Substances 0.000 claims description 3
- 229940079593 drug Drugs 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 238000000034 method Methods 0.000 description 17
- 201000010099 disease Diseases 0.000 description 14
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 14
- 241000699666 Mus <mouse, genus> Species 0.000 description 7
- 208000005764 Peripheral Arterial Disease Diseases 0.000 description 4
- 208000030831 Peripheral arterial occlusive disease Diseases 0.000 description 4
- 241000699670 Mus sp. Species 0.000 description 3
- 102000013918 Apolipoproteins E Human genes 0.000 description 2
- 108010025628 Apolipoproteins E Proteins 0.000 description 2
- 241000282472 Canis lupus familiaris Species 0.000 description 2
- 241000283707 Capra Species 0.000 description 2
- 241000282326 Felis catus Species 0.000 description 2
- 241001494479 Pecora Species 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- 208000026106 cerebrovascular disease Diseases 0.000 description 2
- 208000029078 coronary artery disease Diseases 0.000 description 2
- 208000031225 myocardial ischemia Diseases 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 229960001005 tuberculin Drugs 0.000 description 2
- 108010002352 Interleukin-1 Proteins 0.000 description 1
- 241000282887 Suidae Species 0.000 description 1
- 241000282898 Sus scrofa Species 0.000 description 1
- 230000003053 immunization Effects 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80002906P | 2006-05-15 | 2006-05-15 | |
| PCT/IB2007/001264 WO2007132338A2 (en) | 2006-05-15 | 2007-05-15 | IL-1α IMMUNIZATION INDUCES AUTOANTIBODIES PROTECTIVE AGAINST ATHEROSCLEROSIS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009537507A JP2009537507A (ja) | 2009-10-29 |
| JP2009537507A5 true JP2009537507A5 (https=) | 2010-07-01 |
Family
ID=38694276
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009510567A Pending JP2009537507A (ja) | 2006-05-15 | 2007-05-15 | アテローム性動脈硬化症に対して保護的な自己抗体を誘導するＩＬ−１α免疫法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20090191149A1 (https=) |
| EP (1) | EP2021033B1 (https=) |
| JP (1) | JP2009537507A (https=) |
| CN (1) | CN101448528A (https=) |
| AT (1) | ATE551365T1 (https=) |
| AU (1) | AU2007251239B2 (https=) |
| CA (1) | CA2652274A1 (https=) |
| ES (1) | ES2384278T3 (https=) |
| WO (1) | WO2007132338A2 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1915620T3 (da) | 2005-08-02 | 2010-10-04 | Xbiotech Inc | Diagnose, behandling og prævention af vaskulære sygdomme ved hjælp af IL-1alpha-autoantistoffer |
| US20110008282A1 (en) * | 2006-05-15 | 2011-01-13 | Xbiotech, Inc. | IL-1alpha immunization induces autoantibodies protective against atherosclerosis |
| CN102580086A (zh) * | 2006-05-22 | 2012-07-18 | 埃克斯生物科技公司 | 使用抗IL-1α抗体治疗癌症 |
| CA2726345C (en) | 2008-05-30 | 2018-08-28 | John Simard | Interleukin-1 alpha antibodies and methods of use |
| AU2009291536B2 (en) * | 2008-09-12 | 2012-08-16 | Xbiotech Inc. | Targeting pathogenic monocytes |
| EP2569640A1 (en) | 2010-05-12 | 2013-03-20 | The University of Birmingham | Biomarker |
| KR102167261B1 (ko) | 2010-06-18 | 2020-10-20 | 엑스바이오테크, 인크. | 관절염 치료 |
| US10294296B2 (en) | 2010-08-23 | 2019-05-21 | Xbiotech, Inc. | Treatment for neoplastic diseases |
| US9724409B2 (en) | 2011-04-01 | 2017-08-08 | Xbiotech, Inc. | Treatment of inflammatory skin disease |
| ES2695102T3 (es) | 2011-09-23 | 2019-01-02 | Xbiotech Inc | Tratamiento para la caquexia |
| US9545441B2 (en) | 2012-09-18 | 2017-01-17 | Xbiotech, Inc. | Treatment of diabetes |
| JP6456015B2 (ja) * | 2013-07-19 | 2019-01-23 | 国立大学法人三重大学 | 閉塞性動脈硬化症モデル動物、るい痩研究用モデル動物、及び全身性アミロイドーシスモデル動物としての非ヒト哺乳動物 |
| CN105175504A (zh) * | 2015-09-08 | 2015-12-23 | 苏州普罗达生物科技有限公司 | 血管性血友病因子抑制多肽及其应用 |
| CN105175503A (zh) * | 2015-09-08 | 2015-12-23 | 苏州普罗达生物科技有限公司 | 因子viii抑制多肽及其应用 |
| CA3053231A1 (en) | 2017-02-16 | 2018-08-23 | Xbiotech Inc. | Treatment of hidradenitis suppurativa |
| US10975146B2 (en) | 2018-06-29 | 2021-04-13 | Cedars-Sinai Medical Center | Interleukin-1 inhibition for combination treatment of pancreatic cancer |
| CA3095676A1 (en) | 2020-10-07 | 2022-04-07 | Xbiotech Inc. | True human antibody specific for interleukin 1 alpha (il-1a) |
| CA3095675A1 (en) | 2020-10-07 | 2022-04-07 | Xbiotech Inc. | True human antibody specific for interleukin 1 alpha (il-1a) |
| CA3095740A1 (en) | 2020-10-07 | 2022-04-07 | Xbiotech Inc. | True human antibody specific for interleukin alpha (il-1a) |
| CA3095679A1 (en) | 2020-10-07 | 2022-04-07 | Xbiotech Inc. | True human antibody specific for interleuken 1 alpha (il-1a) |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9802402D0 (sv) * | 1998-07-03 | 1998-07-03 | Karolinska Innovations Ab | Method of diagnosing cardiovascular disease and early atherosclerosis |
| WO2000009118A1 (en) * | 1998-08-13 | 2000-02-24 | The Wistar Institute | Methods for reducing atherosclerotic plaques |
| US20030040617A9 (en) * | 1999-03-12 | 2003-02-27 | Rosen Craig A. | Nucleic acids, proteins and antibodies |
| US20030232054A1 (en) * | 2000-01-25 | 2003-12-18 | Tang Y. Tom | Novel nucleic acids and polypeptides |
| US20030026806A1 (en) * | 2000-10-27 | 2003-02-06 | Amgen Inc. | Antibodies and other selective IL-1 binding agents that allow binding to IL-1 receptor but not activation thereof |
| US20040224893A1 (en) * | 2003-05-06 | 2004-11-11 | Li-Hsien Wang | Methods of using IL-1 antagonists to treat neointimal hyperplasia |
| HN2004000285A (es) * | 2003-08-04 | 2006-04-27 | Pfizer Prod Inc | ANTICUERPOS DIRIGIDOS A c-MET |
| DK1915620T3 (da) | 2005-08-02 | 2010-10-04 | Xbiotech Inc | Diagnose, behandling og prævention af vaskulære sygdomme ved hjælp af IL-1alpha-autoantistoffer |
| CN101267834B (zh) | 2005-09-28 | 2013-06-05 | 赛托斯生物技术公司 | 白介素-1偶联物及其用途 |
| CA2726345C (en) * | 2008-05-30 | 2018-08-28 | John Simard | Interleukin-1 alpha antibodies and methods of use |
| AU2009291536B2 (en) * | 2008-09-12 | 2012-08-16 | Xbiotech Inc. | Targeting pathogenic monocytes |
-
2007
- 2007-05-15 WO PCT/IB2007/001264 patent/WO2007132338A2/en not_active Ceased
- 2007-05-15 US US12/300,712 patent/US20090191149A1/en not_active Abandoned
- 2007-05-15 JP JP2009510567A patent/JP2009537507A/ja active Pending
- 2007-05-15 AU AU2007251239A patent/AU2007251239B2/en active Active
- 2007-05-15 ES ES07734572T patent/ES2384278T3/es active Active
- 2007-05-15 EP EP07734572A patent/EP2021033B1/en active Active
- 2007-05-15 CA CA002652274A patent/CA2652274A1/en not_active Abandoned
- 2007-05-15 CN CNA2007800186140A patent/CN101448528A/zh active Pending
- 2007-05-15 AT AT07734572T patent/ATE551365T1/de active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2009537507A5 (https=) | ||
| JP2009544279A5 (https=) | ||
| JP2012505837A5 (https=) | ||
| MX339469B (es) | Agentes inductores de apotosis para el tratamiento de cancer y enfermedades inmunes y autoinmunes. | |
| JP2008508859A5 (https=) | ||
| RU2015149387A (ru) | Способы применения интерлейкина-10 для лечения заболеваний и расстройств | |
| UA116871C2 (uk) | СПОСІБ ЛІКУВАННЯ МІЄЛОДИСПЛАСТИЧНОГО СИНДРОМУ, ТАЛАСЕМІЇ ТА СЕРПОПОДІБНО-КЛІТИННОЇ АНЕМІЇ ЗА ДОПОМОГОЮ ЗАСТОСУВАННЯ АНТАГОНІСТА АКТИВІНУ ПОЛІПЕПТИДУ ActRII | |
| SMT201300095B (it) | Uso dell'estere etilico dell'acido eicosapentaenoico per trattare l'ipertrigliceridemia | |
| NO20074999L (no) | Metode og preparat for behandling av perifere vaskulaere sykdommer | |
| JP2005537234A5 (https=) | ||
| UY32681A (es) | Agentes inductores de apoptosis para el tratamiento de cáncer y enfermedades inmunes y autoinmunes | |
| NO20056223L (no) | Preparat til behandling av infeksjon hos kveg og svin | |
| JP2016516074A5 (https=) | ||
| EA200801427A1 (ru) | Молекулы антитела со специфической активностью в отношении интерлейкина-6 (ил-6) человека | |
| JP6640725B2 (ja) | ｓｐａｄｉｎのレトロ−インベルソ類似体は増大された抗うつ作用を示す | |
| McElroy et al. | The development of oral lesions in lambs naturally infected with orf virus | |
| JP2013510169A5 (https=) | ||
| JP2014508164A5 (https=) | ||
| BRPI0508434A (pt) | usos de 1-aminociclohexano para o tratamento de distúrbios comportamentais associados ao mal de alzheimer | |
| EA200900330A1 (ru) | Аналоги 2-феноксипиримидинона | |
| MX2012001708A (es) | Anticuerpo humanizado anti-oligomero de amiloide b. | |
| WO2006026135A3 (en) | Substituted biaryl piperazinyl-pyridine analogues | |
| WO2006076646A3 (en) | Heteroaryl substituted quinolin-4-ylamine analogues | |
| Emikpe et al. | Ex-vivo evaluation of the mucoadhesive properties of Cedrela odorata and Khaya senegalensis gums with possible applications for veterinary vaccine delivery | |
| Colpo et al. | Promises and pitfalls of immune-based strategies for Huntington's disease |