JP2009535025A5 - - Google Patents
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- Publication number
- JP2009535025A5 JP2009535025A5 JP2009507144A JP2009507144A JP2009535025A5 JP 2009535025 A5 JP2009535025 A5 JP 2009535025A5 JP 2009507144 A JP2009507144 A JP 2009507144A JP 2009507144 A JP2009507144 A JP 2009507144A JP 2009535025 A5 JP2009535025 A5 JP 2009535025A5
- Authority
- JP
- Japan
- Prior art keywords
- substrate
- substrate according
- poly
- cell culture
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000000758 substrate Substances 0.000 claims 36
- 238000004113 cell culture Methods 0.000 claims 9
- 239000011248 coating agent Substances 0.000 claims 6
- 238000000576 coating method Methods 0.000 claims 6
- 229920001971 elastomer Polymers 0.000 claims 6
- 239000000806 elastomer Substances 0.000 claims 6
- GOXQRTZXKQZDDN-UHFFFAOYSA-N 2-Ethylhexyl acrylate Chemical group CCCCC(CC)COC(=O)C=C GOXQRTZXKQZDDN-UHFFFAOYSA-N 0.000 claims 4
- 230000002209 hydrophobic effect Effects 0.000 claims 4
- 239000002861 polymer material Substances 0.000 claims 4
- 238000002360 preparation method Methods 0.000 claims 4
- 239000004094 surface-active agent Substances 0.000 claims 4
- 239000012528 membrane Substances 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 229920002554 vinyl polymer Polymers 0.000 claims 3
- JAMNSIXSLVPNLC-UHFFFAOYSA-N (4-ethenylphenyl) acetate Chemical compound CC(=O)OC1=CC=C(C=C)C=C1 JAMNSIXSLVPNLC-UHFFFAOYSA-N 0.000 claims 2
- MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 claims 2
- VJJZJBUCDWKPLC-UHFFFAOYSA-N 3-methoxyapigenin Chemical compound O1C2=CC(O)=CC(O)=C2C(=O)C(OC)=C1C1=CC=C(O)C=C1 VJJZJBUCDWKPLC-UHFFFAOYSA-N 0.000 claims 2
- SOGAXMICEFXMKE-UHFFFAOYSA-N Butylmethacrylate Chemical group CCCCOC(=O)C(C)=C SOGAXMICEFXMKE-UHFFFAOYSA-N 0.000 claims 2
- 102000008186 Collagen Human genes 0.000 claims 2
- 108010035532 Collagen Proteins 0.000 claims 2
- 239000004793 Polystyrene Substances 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 229920001436 collagen Polymers 0.000 claims 2
- KBLWLMPSVYBVDK-UHFFFAOYSA-N cyclohexyl prop-2-enoate Chemical compound C=CC(=O)OC1CCCCC1 KBLWLMPSVYBVDK-UHFFFAOYSA-N 0.000 claims 2
- LNCPIMCVTKXXOY-UHFFFAOYSA-N hexyl 2-methylprop-2-enoate Chemical compound CCCCCCOC(=O)C(C)=C LNCPIMCVTKXXOY-UHFFFAOYSA-N 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 239000000178 monomer Substances 0.000 claims 2
- 229920000620 organic polymer Polymers 0.000 claims 2
- WRAQQYDMVSCOTE-UHFFFAOYSA-N phenyl prop-2-enoate Chemical compound C=CC(=O)OC1=CC=CC=C1 WRAQQYDMVSCOTE-UHFFFAOYSA-N 0.000 claims 2
- 229920002223 polystyrene Polymers 0.000 claims 2
- 239000011148 porous material Substances 0.000 claims 2
- 230000035755 proliferation Effects 0.000 claims 2
- 239000002023 wood Substances 0.000 claims 2
- HMDQPBSDHHTRNI-UHFFFAOYSA-N 1-(chloromethyl)-3-ethenylbenzene Chemical compound ClCC1=CC=CC(C=C)=C1 HMDQPBSDHHTRNI-UHFFFAOYSA-N 0.000 claims 1
- 239000004908 Emulsion polymer Substances 0.000 claims 1
- 102000016359 Fibronectins Human genes 0.000 claims 1
- 108010067306 Fibronectins Proteins 0.000 claims 1
- 102000007547 Laminin Human genes 0.000 claims 1
- 108010085895 Laminin Proteins 0.000 claims 1
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical group C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 claims 1
- KCXMKQUNVWSEMD-UHFFFAOYSA-N benzyl chloride Chemical compound ClCC1=CC=CC=C1 KCXMKQUNVWSEMD-UHFFFAOYSA-N 0.000 claims 1
- 229940073608 benzyl chloride Drugs 0.000 claims 1
- CQEYYJKEWSMYFG-UHFFFAOYSA-N butyl acrylate Chemical compound CCCCOC(=O)C=C CQEYYJKEWSMYFG-UHFFFAOYSA-N 0.000 claims 1
- 239000003054 catalyst Substances 0.000 claims 1
- 239000006143 cell culture medium Substances 0.000 claims 1
- 230000024245 cell differentiation Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- OIWOHHBRDFKZNC-UHFFFAOYSA-N cyclohexyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OC1CCCCC1 OIWOHHBRDFKZNC-UHFFFAOYSA-N 0.000 claims 1
- 230000004069 differentiation Effects 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- LNMQRPPRQDGUDR-UHFFFAOYSA-N hexyl prop-2-enoate Chemical compound CCCCCCOC(=O)C=C LNMQRPPRQDGUDR-UHFFFAOYSA-N 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 230000004048 modification Effects 0.000 claims 1
- 238000012986 modification Methods 0.000 claims 1
- QIWKUEJZZCOPFV-UHFFFAOYSA-N phenyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OC1=CC=CC=C1 QIWKUEJZZCOPFV-UHFFFAOYSA-N 0.000 claims 1
- 229920000729 poly(L-lysine) polymer Polymers 0.000 claims 1
- 229920001490 poly(butyl methacrylate) polymer Polymers 0.000 claims 1
- 229920002776 polycyclohexyl methacrylate Polymers 0.000 claims 1
- 108010055896 polyornithine Proteins 0.000 claims 1
- 229920000182 polyphenyl methacrylate Polymers 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0608403A GB0608403D0 (en) | 2006-04-28 | 2006-04-28 | Substrate for the routine growth of cultured cells in three dimensions |
| GB0610120A GB0610120D0 (en) | 2006-05-20 | 2006-05-20 | Substrate for the routine growth of cultured cells in three dimensions |
| GB0700592A GB0700592D0 (en) | 2007-01-12 | 2007-01-12 | Substrate for the routine growth of cultured cells in three D dimensions |
| PCT/GB2007/001464 WO2007125288A1 (en) | 2006-04-28 | 2007-04-24 | Substrate for the growth of cultured cells in three dimensions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014019401A Division JP2014097068A (ja) | 2006-04-28 | 2014-02-04 | 三次元での細胞培養のルーチン成長のための基材 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009535025A JP2009535025A (ja) | 2009-10-01 |
| JP2009535025A5 true JP2009535025A5 (enExample) | 2010-06-17 |
Family
ID=38290111
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009507144A Pending JP2009535025A (ja) | 2006-04-28 | 2007-04-24 | 三次元での細胞培養のルーチン成長のための基材 |
| JP2014019401A Pending JP2014097068A (ja) | 2006-04-28 | 2014-02-04 | 三次元での細胞培養のルーチン成長のための基材 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014019401A Pending JP2014097068A (ja) | 2006-04-28 | 2014-02-04 | 三次元での細胞培養のルーチン成長のための基材 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20100048411A1 (enExample) |
| EP (1) | EP2018418B1 (enExample) |
| JP (2) | JP2009535025A (enExample) |
| AU (1) | AU2007245453B2 (enExample) |
| BR (1) | BRPI0710777A2 (enExample) |
| CA (1) | CA2650488A1 (enExample) |
| IL (1) | IL194894A (enExample) |
| MX (1) | MX2008013885A (enExample) |
| WO (1) | WO2007125288A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007125288A1 (en) * | 2006-04-28 | 2007-11-08 | Reinnervate Limited | Substrate for the growth of cultured cells in three dimensions |
| WO2009059115A1 (en) * | 2007-10-31 | 2009-05-07 | Trustees Of The University Of Pennsylvania | Culture based screening assay and methods of use thereof to identify agents which modulate tumor development, invasion and differentiation |
| AU2011263652B2 (en) | 2010-06-11 | 2014-11-20 | Takara Bio Europe Ab | 3-dimensional scaffolds for improved differentiation of pluripotent stem cells to hepatocytes |
| US9534206B2 (en) * | 2010-12-16 | 2017-01-03 | General Electric Company | Cell carrier, associated methods for making cell carrier and culturing cells using the same |
| US9926523B2 (en) * | 2010-12-16 | 2018-03-27 | General Electric Company | Cell carriers and methods for culturing cells |
| US9518249B2 (en) * | 2010-12-16 | 2016-12-13 | General Electric Company | Cell carrier, associated methods for making cell carrier and culturing cells using the same |
| US9453196B2 (en) | 2010-12-16 | 2016-09-27 | General Electric Company | Cell carrier, methods of making and use |
| US9453197B2 (en) | 2010-12-16 | 2016-09-27 | General Electric Company | Methods of making cell carrier |
| US8981025B2 (en) | 2011-02-10 | 2015-03-17 | Corning Incorporated | Polymerizable catonic peptide monomers and polymers |
| RU2612915C2 (ru) * | 2011-02-28 | 2017-03-13 | Президент Энд Феллоуз Ов Харвард Колледж | Система культивирования клеток |
| WO2013050921A1 (en) | 2011-10-03 | 2013-04-11 | Piramal Enterprises Limited | Hollow polymer microspheres as three-dimensional cell culture matrix |
| JP2013215152A (ja) * | 2012-04-11 | 2013-10-24 | Vessel Inc | ３次元細胞培養プレートとその製造方法 |
| US20170363614A1 (en) * | 2014-12-22 | 2017-12-21 | Enumeral Biomedical Holdings, Inc. | Methods For Screening Therapeutic Compounds |
| WO2018008985A2 (ko) * | 2016-07-05 | 2018-01-11 | 한국과학기술원 | 세포시트 제작방법 및 응용을 위한 고분자 박막 배양플레이트 제작방법 및 용도 |
| CA3036378A1 (en) | 2016-09-13 | 2018-03-22 | President And Fellows Of Harvard College | Methods relating to intestinal organ-on-a-chip |
| CN109952379A (zh) * | 2016-11-14 | 2019-06-28 | 白雁生物技术公司 | 将外源性线粒体递送到细胞中的方法 |
| EP3431582A1 (en) * | 2017-07-18 | 2019-01-23 | Koninklijke Philips N.V. | Cell culturing materials |
| US20230312801A1 (en) * | 2020-08-09 | 2023-10-05 | Technion Research & Development Foundation Limited | Highly porous poly(lactic acid) monoliths |
| US20240082462A1 (en) | 2021-01-08 | 2024-03-14 | Fraunhofer-Gesellschaft Zurförderung Der Angewandten Forschung E.V. | High-porosity nanofiber nonwovens as a support structure for stromal tissue |
| DE102021201935A1 (de) | 2021-01-08 | 2022-07-14 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung eingetragener Verein | Hochporöse Nanofaservliese als Trägerstruktur für stromales Gewebe |
| WO2024071109A1 (ja) * | 2022-09-30 | 2024-04-04 | インテグリカルチャー株式会社 | 細胞培養装置、細胞培養システム、培養肉、及び培養上清 |
| CN117625394B (zh) * | 2023-12-01 | 2024-12-06 | 东莞合安机电有限公司 | 一种荔枝菌菌种培养液、制备方法及培养方法 |
| WO2025244512A1 (ko) * | 2024-05-23 | 2025-11-27 | 주식회사 엘지화학 | 세포 배양용 마이크로 캐리어, 세포 배양용 마이크로 캐리어의 제조 방법 및 이를 이용한 세포 배양 조성물 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL75554A (en) * | 1985-06-18 | 1993-01-14 | Yeda Res & Dev | Matrix for cell cultivation in vitro |
| US5266476A (en) * | 1985-06-18 | 1993-11-30 | Yeda Research & Development Co., Ltd. | Fibrous matrix for in vitro cell cultivation |
| GB8729889D0 (en) * | 1987-12-22 | 1988-02-03 | Unilever Plc | Bio-catalysts support systems |
| US6471993B1 (en) * | 1997-08-01 | 2002-10-29 | Massachusetts Institute Of Technology | Three-dimensional polymer matrices |
| US6281257B1 (en) * | 1998-04-27 | 2001-08-28 | The Regents Of The University Of Michigan | Porous composite materials |
| GB9826701D0 (en) * | 1998-12-05 | 1999-01-27 | Univ Newcastle | Microcellular polymers as cell growth media and novel polymers |
| TW591106B (en) * | 2000-10-06 | 2004-06-11 | Ind Tech Res Inst | Carrier for cell attachment or fixation and its process for preparation |
| WO2007125288A1 (en) * | 2006-04-28 | 2007-11-08 | Reinnervate Limited | Substrate for the growth of cultured cells in three dimensions |
-
2007
- 2007-04-24 WO PCT/GB2007/001464 patent/WO2007125288A1/en not_active Ceased
- 2007-04-24 US US12/298,742 patent/US20100048411A1/en not_active Abandoned
- 2007-04-24 BR BRPI0710777-3A patent/BRPI0710777A2/pt not_active IP Right Cessation
- 2007-04-24 CA CA002650488A patent/CA2650488A1/en not_active Abandoned
- 2007-04-24 AU AU2007245453A patent/AU2007245453B2/en not_active Ceased
- 2007-04-24 EP EP07732504.1A patent/EP2018418B1/en not_active Not-in-force
- 2007-04-24 JP JP2009507144A patent/JP2009535025A/ja active Pending
- 2007-04-24 MX MX2008013885A patent/MX2008013885A/es not_active Application Discontinuation
-
2008
- 2008-10-23 IL IL194894A patent/IL194894A/en not_active IP Right Cessation
-
2014
- 2014-02-04 JP JP2014019401A patent/JP2014097068A/ja active Pending
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