JP2009532369A - 分泌性白血球プロテアーゼインヒビターによる神経再生の刺激 - Google Patents

分泌性白血球プロテアーゼインヒビターによる神経再生の刺激 Download PDF

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JP2009532369A
JP2009532369A JP2009503084A JP2009503084A JP2009532369A JP 2009532369 A JP2009532369 A JP 2009532369A JP 2009503084 A JP2009503084 A JP 2009503084A JP 2009503084 A JP2009503084 A JP 2009503084A JP 2009532369 A JP2009532369 A JP 2009532369A
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slpi
neuron
disease
neurons
patient
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JP2009532369A5 (enExample
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マリー ティー. フィルビン,
サリー エス. ハニラ,
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Research Foundation of City University of New York
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Research Foundation of City University of New York
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/57Protease inhibitors from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Psychology (AREA)
  • Zoology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2009503084A 2006-03-30 2007-03-30 分泌性白血球プロテアーゼインヒビターによる神経再生の刺激 Pending JP2009532369A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78802106P 2006-03-30 2006-03-30
US78792706P 2006-03-31 2006-03-31
PCT/US2007/008270 WO2007117440A2 (en) 2006-03-30 2007-03-30 Stimulation of neuron regeneration by secretory leukocyte protease inhibitor

Publications (2)

Publication Number Publication Date
JP2009532369A true JP2009532369A (ja) 2009-09-10
JP2009532369A5 JP2009532369A5 (enExample) 2010-05-20

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JP2009503084A Pending JP2009532369A (ja) 2006-03-30 2007-03-30 分泌性白血球プロテアーゼインヒビターによる神経再生の刺激

Country Status (5)

Country Link
US (1) US8367615B2 (enExample)
EP (1) EP2012819A2 (enExample)
JP (1) JP2009532369A (enExample)
CA (1) CA2647246C (enExample)
WO (1) WO2007117440A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014528913A (ja) * 2011-06-28 2014-10-30 インヒブルクス リミティド ライアビリティ カンパニー Wapドメイン融合ポリペプチド及びその使用方法

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10400029B2 (en) 2011-06-28 2019-09-03 Inhibrx, Lp Serpin fusion polypeptides and methods of use thereof
CA2839619C (en) 2011-06-28 2021-11-16 Inhibrx Llc Serpin fusion polypeptides and methods of use thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004537970A (ja) * 2000-12-18 2004-12-24 アライバ ファーマシューティカルズ,インコーポレイティド 多機能性プロテアーゼインヒビターおよびそれらの疾患治療における使用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5650148A (en) 1988-12-15 1997-07-22 The Regents Of The University Of California Method of grafting genetically modified cells to treat defects, disease or damage of the central nervous system
US6017880A (en) * 1994-03-09 2000-01-25 Amgen Inc. Inhibition of retrovirus infection
US6551618B2 (en) 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival
EP0755454B1 (en) 1994-04-13 2008-02-13 The Rockefeller University Aav-mediated delivery of dna to cells of the nervous system
US6096716A (en) 1994-12-12 2000-08-01 The Board Of Regents, The University Of Texas System Liposome-mediated transfection of central nervous system cells
DE69633336T2 (de) 1995-06-27 2005-09-22 Research Foundation Of Cuny Zusamenzetzung enthaltend einen inhibitor des myelin assoziierten glycoproteins (mag), welcher einer veränderten oder mutierten form von mag enthält
WO1997032608A1 (en) 1996-03-04 1997-09-12 University Of Medicine & Dentistry Of New Jersey Genetically engineered primary oligodendrocytes for transplantation-mediated gene delivery in the central nervous system
US6210664B1 (en) 1996-04-08 2001-04-03 New York University Medical Center Method for gene transfer to the central nervous system
US7544511B2 (en) 1996-09-25 2009-06-09 Neuralstem Biopharmaceuticals Ltd. Stable neural stem cell line methods
US5968829A (en) 1997-09-05 1999-10-19 Cytotherapeutics, Inc. Human CNS neural stem cells
US5981225A (en) 1998-04-16 1999-11-09 Baylor College Of Medicine Gene transfer vector, recombinant adenovirus particles containing the same, method for producing the same and method of use of the same
GB9816775D0 (en) 1998-07-31 1998-09-30 Efstathiou Stacey Herpesviral vectors for gene delivery
WO2001003719A2 (en) * 1999-07-09 2001-01-18 Amgen Inc. Combination therapy for conditions leading to bone loss
CA2408255A1 (en) 2000-05-05 2001-11-15 Marie T. Filbin Methods for stimulating nervous system regeneration and repair by regulating arginase 1 and polyamine synthesis
WO2003016539A1 (en) 2001-03-13 2003-02-27 Thomas Jefferson University Retroviral vectors for gene transfer into neuronal cells
US20090232910A1 (en) * 2004-07-22 2009-09-17 Duke University Biomarkers and therapeutics targets for cognitive decline

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004537970A (ja) * 2000-12-18 2004-12-24 アライバ ファーマシューティカルズ,インコーポレイティド 多機能性プロテアーゼインヒビターおよびそれらの疾患治療における使用

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN6012028369; Molecular Pharmacology Vol.64, No.4, 2003, p.833-840 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014528913A (ja) * 2011-06-28 2014-10-30 インヒブルクス リミティド ライアビリティ カンパニー Wapドメイン融合ポリペプチド及びその使用方法

Also Published As

Publication number Publication date
CA2647246A1 (en) 2007-10-18
EP2012819A2 (en) 2009-01-14
US20100256065A1 (en) 2010-10-07
WO2007117440A3 (en) 2008-04-17
WO2007117440A2 (en) 2007-10-18
CA2647246C (en) 2015-06-23
US8367615B2 (en) 2013-02-05

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