JP2009526024A - ニコチン性アセチルコリン受容体アゴニストとしての３−ヘテロアリール−３，９−ジアザビシクロ［３．３．１］ノナン誘導体 - Google Patents
ニコチン性アセチルコリン受容体アゴニストとしての３−ヘテロアリール−３，９−ジアザビシクロ［３．３．１］ノナン誘導体 Download PDFInfo
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- JP2009526024A JP2009526024A JP2008553777A JP2008553777A JP2009526024A JP 2009526024 A JP2009526024 A JP 2009526024A JP 2008553777 A JP2008553777 A JP 2008553777A JP 2008553777 A JP2008553777 A JP 2008553777A JP 2009526024 A JP2009526024 A JP 2009526024A
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- nonane
- alkyl
- diaza
- bicyclo
- methyl
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Landscapes
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| Application Number | Priority Date | Filing Date | Title |
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| US77189006P | 2006-02-10 | 2006-02-10 | |
| DKPA200600190 | 2006-02-10 | ||
| PCT/EP2007/051272 WO2007090888A1 (en) | 2006-02-10 | 2007-02-09 | 3-heteroaryl- 3,9-diazabicyclo[3.3.1]nonane derivatives as nicotinic acetylcholine receptor agonists |
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| JP2009526024A true JP2009526024A (ja) | 2009-07-16 |
| JP2009526024A5 JP2009526024A5 (https=) | 2010-04-02 |
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| EP (1) | EP1987031A1 (https=) |
| JP (1) | JP2009526024A (https=) |
| AU (1) | AU2007213671A1 (https=) |
| CA (1) | CA2641685A1 (https=) |
| WO (1) | WO2007090888A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| AU2007213670A1 (en) | 2006-02-10 | 2007-08-16 | Neurosearch A/S | 3,9-diazabicyclo[3.3.1]nonane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| CN101379063A (zh) | 2006-02-10 | 2009-03-04 | 神经研究公司 | 3,9-二氮杂双环[3.3.1]壬烷衍生物及其作为单胺神经递质再摄取抑制剂的用途 |
| JP2011504909A (ja) * | 2007-11-30 | 2011-02-17 | ノイロサーチ アクティーゼルスカブ | 新規なカルボン酸４−フェニルアゾ−フェニルエステル誘導体及びモノアミン神経伝達物質再取り込み阻害薬としてのそれらの使用 |
| US8148408B2 (en) | 2008-05-09 | 2012-04-03 | Abbott Laboratories | Selective substituted pyridine ligands for neuronal nicotinic receptors |
| EP2288609A2 (en) * | 2008-06-10 | 2011-03-02 | NeuroSearch A/S | Indolyl-pyridazinyl-diazabicyclononane derivatives in labelled and unlabelled form and their use in diagnostic methods |
| TW201004963A (en) * | 2008-07-03 | 2010-02-01 | Targacept Inc | Derivatives of oxabispidine as neuronal nicotinic acetylcholine receptor ligands |
| US20180311238A1 (en) * | 2017-04-28 | 2018-11-01 | Saniona A/S | Selective Agonist Of a6 Containing nAChRs |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US3196154A (en) | 1962-05-17 | 1965-07-20 | Sterling Drug Inc | 3-substituted-9-methyl-3, 9-diazabicyclo [3.3.1] nonanes |
| IN166416B (https=) | 1985-09-18 | 1990-05-05 | Pfizer | |
| US5478939A (en) * | 1994-07-20 | 1995-12-26 | American Cyanamid Company | (R,R) and (S,S) 2,5-diazabicyclo [2,2,1]heptane derivatives |
| WO1998054182A1 (en) | 1997-05-30 | 1998-12-03 | Neurosearch A/S | 9-AZABICYCLO(3.3.1)NON-2-ENE AND NONANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACh RECEPTORS |
| KR100589872B1 (ko) | 1997-05-30 | 2006-06-15 | 뉴로서치 에이/에스 | 8-아자비사이클로(3,2,1)옥트-2-엔 유도체 및 이의 제조방법 |
| ATE273970T1 (de) | 1998-04-16 | 2004-09-15 | Pfizer Prod Inc | N-acyl und n-aroyl aralkylamide |
| FR2786770B1 (fr) | 1998-12-04 | 2001-01-19 | Synthelabo | Derives de 1,4-diazabicyclo[3.2.2.]nonane, leur preparation et leur application en therapeutique |
| ES2305373T3 (es) | 1999-01-29 | 2008-11-01 | Abbott Laboratories | Derivados diazabiciclicos como ligandos del receptor nicotinico de la acetilcolina. |
| US7265115B2 (en) * | 1999-01-29 | 2007-09-04 | Abbott Laboratories | Diazabicyclic CNS active agents |
| NZ513575A (en) | 1999-05-04 | 2003-07-25 | Neurosearch As | Heteroaryl diazabicycloalkanes useful for treating or preventing a disease or a disorder responsive to the activity of nAChR modulators |
| JP2003534344A (ja) | 2000-05-25 | 2003-11-18 | ターガセプト，インコーポレイテッド | ニコチン性コリン受容体リガンドとしてのヘテロアリールジアザビシクロアルカン |
| NZ522793A (en) | 2000-07-04 | 2005-02-25 | Neurosearch As | Aryl and heteroaryl diazabicycloalkanes, their preparation and use |
| DE60203007T2 (de) | 2001-06-01 | 2005-07-07 | Neurosearch A/S | Heteroaryl-diazabicycloalkanderivaten als cns-modulatoren |
| US7399765B2 (en) * | 2003-09-19 | 2008-07-15 | Abbott Laboratories | Substituted diazabicycloalkane derivatives |
| JP2007510642A (ja) | 2003-11-03 | 2007-04-26 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | 中枢神経系障害の治療のための新規ノルエピネフリン再取込み阻害薬 |
| ATE493415T1 (de) | 2004-10-20 | 2011-01-15 | Neurosearch As | Neue diazabizyklische arylderivate und medizinische verwendung dafür |
| CA2585172C (en) | 2004-10-29 | 2014-08-12 | Kalypsys, Inc. | Sulfonyl-substituted bicyclic compounds as modulators of ppar |
| WO2006087306A2 (en) | 2005-02-16 | 2006-08-24 | Neurosearch A/S | Diazabicyclic aryl derivatives and their use as cholinergic ligands at the nicotinic acetylcholine receptors |
| ATE473978T1 (de) | 2005-12-06 | 2010-07-15 | Neurosearch As | Neue diazabicyclische arylderivate und medizinische verwendung dafür |
| AU2007213670A1 (en) | 2006-02-10 | 2007-08-16 | Neurosearch A/S | 3,9-diazabicyclo[3.3.1]nonane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| CN101379063A (zh) | 2006-02-10 | 2009-03-04 | 神经研究公司 | 3,9-二氮杂双环[3.3.1]壬烷衍生物及其作为单胺神经递质再摄取抑制剂的用途 |
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2007
- 2007-02-09 WO PCT/EP2007/051272 patent/WO2007090888A1/en not_active Ceased
- 2007-02-09 CA CA002641685A patent/CA2641685A1/en not_active Abandoned
- 2007-02-09 EP EP07704487A patent/EP1987031A1/en not_active Withdrawn
- 2007-02-09 JP JP2008553777A patent/JP2009526024A/ja not_active Abandoned
- 2007-02-09 US US12/087,004 patent/US7687523B2/en active Active
- 2007-02-09 AU AU2007213671A patent/AU2007213671A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1987031A1 (en) | 2008-11-05 |
| US20090005388A1 (en) | 2009-01-01 |
| CA2641685A1 (en) | 2007-08-16 |
| AU2007213671A1 (en) | 2007-08-16 |
| WO2007090888A1 (en) | 2007-08-16 |
| US7687523B2 (en) | 2010-03-30 |
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