JP2009523014A - 活性化プロテインc又はプロテインc様化合物投与に対する反応予測因子としてのプロテインcパスウェイ関連多型性 - Google Patents

活性化プロテインc又はプロテインc様化合物投与に対する反応予測因子としてのプロテインcパスウェイ関連多型性 Download PDF

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JP2009523014A
JP2009523014A JP2008549732A JP2008549732A JP2009523014A JP 2009523014 A JP2009523014 A JP 2009523014A JP 2008549732 A JP2008549732 A JP 2008549732A JP 2008549732 A JP2008549732 A JP 2008549732A JP 2009523014 A JP2009523014 A JP 2009523014A
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nucleic acid
seq
acid molecule
oligonucleotide
environment
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JP2009523014A5 (fr
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ラッセル、ジェームズ、エー.
ウォーリー、キース、アール.
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University of British Columbia
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    • AHUMAN NECESSITIES
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    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4866Protein C (3.4.21.69)
    • AHUMAN NECESSITIES
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6464Protein C (3.4.21.69)
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/172Haplotypes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333Saccharide [e.g., DNA, etc.]

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JP2008549732A 2006-01-12 2007-01-12 活性化プロテインc又はプロテインc様化合物投与に対する反応予測因子としてのプロテインcパスウェイ関連多型性 Withdrawn JP2009523014A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75819306P 2006-01-12 2006-01-12
US78302106P 2006-03-17 2006-03-17
PCT/CA2007/000054 WO2007079592A1 (fr) 2006-01-12 2007-01-12 Polymorphismes associés à la voie de la protéine c en tant que prédicteurs de réponse à l'administration de protéine c activée ou d'un composé apparenté à la protéine c

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JP2009523014A true JP2009523014A (ja) 2009-06-18
JP2009523014A5 JP2009523014A5 (fr) 2010-02-25

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JP2008549732A Withdrawn JP2009523014A (ja) 2006-01-12 2007-01-12 活性化プロテインc又はプロテインc様化合物投与に対する反応予測因子としてのプロテインcパスウェイ関連多型性

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Country Link
US (1) US20110027184A1 (fr)
EP (1) EP1982008A4 (fr)
JP (1) JP2009523014A (fr)
AU (1) AU2007204572A1 (fr)
CA (1) CA2636706A1 (fr)
MX (1) MX2008009056A (fr)
WO (1) WO2007079592A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2032748A4 (fr) * 2007-02-16 2009-11-11 Univ British Columbia Uitlisation des polymorphismes de la serpine 1 pour prédire la réponse à l'administration d'une protéine c activée et le risque de décès
US20110171200A1 (en) * 2008-01-15 2011-07-14 Walley Keith R Protein c rs2069915 as a response predictor to survival and administration of activated protein c or protein c-like compound
BR112014027677B1 (pt) * 2012-11-13 2020-12-01 Koninklijke Philips N.V. extrator de suco

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0696325B1 (fr) * 1994-02-14 1998-05-13 Rijksuniversiteit Leiden Procede de depistage d'une anomalie genetique asssocie a la trombose et/ou a une mauvaise reponse anticoagulante a la proteine c activee
AU2003233292A1 (en) * 2002-05-28 2003-12-12 The University Of British Columbia Protein c polymorphisms
US20070281300A1 (en) * 2004-03-04 2007-12-06 James Russell Thrombomodulin (Thbd) Haplotypes Predict Outcome
CA2479968A1 (fr) * 2004-09-01 2006-03-01 Keith R. Walley Polymorphismes de la proteine c et du recepteur de la proteine c endotheliale utilises comme indicateurs de l'evolution de l'etat de sante de patients

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Publication number Publication date
AU2007204572A1 (en) 2007-07-19
US20110027184A1 (en) 2011-02-03
WO2007079592A1 (fr) 2007-07-19
EP1982008A4 (fr) 2009-09-30
EP1982008A1 (fr) 2008-10-22
CA2636706A1 (fr) 2007-07-19
MX2008009056A (es) 2009-01-07

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