JP2009523006A - 脈管疾患に関連する遺伝的多型、その検出方法および使用 - Google Patents

脈管疾患に関連する遺伝的多型、その検出方法および使用 Download PDF

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JP2009523006A
JP2009523006A JP2007511679A JP2007511679A JP2009523006A JP 2009523006 A JP2009523006 A JP 2009523006A JP 2007511679 A JP2007511679 A JP 2007511679A JP 2007511679 A JP2007511679 A JP 2007511679A JP 2009523006 A JP2009523006 A JP 2009523006A
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snp
nucleic acid
snps
protein
seq
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JP2009523006A5 (enExample
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ミシェル カーギル,
ジェームズ デブリン,
メイ ルーク,
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アプレラ コーポレイション
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2007511679A 2004-05-07 2005-05-09 脈管疾患に関連する遺伝的多型、その検出方法および使用 Pending JP2009523006A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56884504P 2004-05-07 2004-05-07
US62593604P 2004-11-09 2004-11-09
PCT/US2005/016076 WO2005110039A2 (en) 2004-05-07 2005-05-09 Genetic polymorphisms associated with vascular diseases, methods of detection and uses thereof

Publications (2)

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JP2009523006A true JP2009523006A (ja) 2009-06-18
JP2009523006A5 JP2009523006A5 (enExample) 2009-07-30

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JP2007511679A Pending JP2009523006A (ja) 2004-05-07 2005-05-09 脈管疾患に関連する遺伝的多型、その検出方法および使用

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US (1) US20050287559A1 (enExample)
EP (1) EP1753875A2 (enExample)
JP (1) JP2009523006A (enExample)
CA (1) CA2566257A1 (enExample)
WO (1) WO2005110039A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018513141A (ja) * 2015-04-20 2018-05-24 コンセジョ スペリオール デ インベスティガショネス シエンティフィカス ヒトカドヘリン−17、ヒトカドヘリン−5、ヒトカドヘリン−6およびヒトカドヘリン−20のrgdモチーフに特異的に結合する薬剤

Families Citing this family (9)

* Cited by examiner, † Cited by third party
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US7666584B2 (en) * 2005-09-01 2010-02-23 Philadelphia Health & Education Coporation Identification of a pin specific gene and protein (PIN-1) useful as a diagnostic treatment for prostate cancer
EP2016197A4 (en) * 2006-04-21 2009-09-16 Celera GENETIC POLYMORPHISMS ASSOCIATED WITH CORONARY DISEASE, DETECTION METHODS AND JOBS
CA2679581C (en) * 2007-02-21 2020-12-22 Anna Helgadottir Genetic susceptibility variants associated with arterial disease
EP2155907B1 (en) * 2007-04-30 2015-05-27 Decode Genetics EHF Genetic variants useful for risk assessment of coronary artery disease and myocardial infarction
BRPI0811309B1 (pt) 2007-05-09 2022-03-03 The Brigham And Women's Hospital, Inc. Métodos in vitro para avaliar uma responsividade do gene apo(a) em uma amostra de ácido nucleico de um indivíduo humano ao tratamento com ácido acetilsalicílico para reduzir o risco de um evento cardiovascular futuro
GB2453173A (en) 2007-09-28 2009-04-01 Dxs Ltd Polynucleotide primers
WO2015100300A2 (en) * 2013-12-23 2015-07-02 Duke University Methods for diagnosing and treating copper-dependent diseases
CA3108324A1 (en) * 2018-07-31 2020-02-06 Cornell University Gene therapy methods to control organ function
EP3935581A4 (en) 2019-03-04 2022-11-30 Iocurrents, Inc. DATA COMPRESSION AND COMMUNICATION USING MACHINE LEARNING

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001514522A (ja) * 1997-03-10 2001-09-11 インターロイキン・ジェネティクス・インコーポレーテッド 冠状動脈疾患の予測
WO2002036770A2 (fr) * 2000-10-31 2002-05-10 Aventis Pharma S.A. Sequences polymorphes du gene humain abca1, leurs utilisations, les methodes et kits de detection
JP2002360275A (ja) * 2000-12-22 2002-12-17 Pfizer Prod Inc 心臓血管疾患に関連する方法、組成物およびキット
JP2003500069A (ja) * 1999-05-24 2003-01-07 インタールーキン ジェネティックス インク 再狭窄の診断及び治療薬
JP2003500071A (ja) * 1999-05-26 2003-01-07 インターロイキン・ジェネティクス・インコーポレーテッド 心血管障害のための診断及び治療
WO2003072813A2 (en) * 2002-02-27 2003-09-04 Bayer Healthcare Ag Single nucleotide polymorphisms predicting adverse drug reactions and medication efficacy

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EP0694080B1 (en) * 1993-04-05 2005-12-07 University of Utah Research Foundation Diagnosis and treatment of supravalvular aortic stenosis
US5658729A (en) * 1994-10-11 1997-08-19 The University Of British Columbia Method, reagent and kit for evaluating susceptibility to premature atherosclerosis
EP0939136A1 (en) * 1998-01-07 1999-09-01 Academisch Ziekenhuis bij de Universiteit van Amsterdam Assay for predicting the angiographic response to lipid-lowering therapy in patients
AU7350598A (en) * 1998-04-27 1999-11-16 Amsterdam Molecular Therapeutics B.V. A frequent mutation in the cystathionine beta-synthase gene increases risk for coronary artery disease
US6297014B1 (en) * 1999-07-02 2001-10-02 Cedars-Sinai Medical Center Genetic test to determine non-responsiveness to statin drug treatment
CA2389956A1 (en) * 1999-11-03 2001-02-10 Zymogenetics, Inc. Follistatin-related protein zfsta4
WO2001053522A2 (en) * 2000-01-20 2001-07-26 Epidauros Biotechnologie Ag (CA)n POLYMORPHISMS IN AN INTRON OF THE ENDOTHELIAL NITRIC OXIDE SYNTHASE GENE AND THEIR USE IN DIAGNOSTIC AND THERAPEUTIC APPLICATIONS
US20050075283A1 (en) * 2001-07-13 2005-04-07 Applera Corporation Isolated human secreted proteins, nucleic acid molecules encoding human secreted proteins, and uses thereof
EP1293569A3 (en) * 2001-09-14 2004-03-31 Research Association for Biotechnology Full-length cDNAs
WO2003093432A2 (en) * 2002-05-02 2003-11-13 Curagen Corporation Therapeutic polypeptides, nucleic acids encoding same, and methods of use
CA2510895A1 (en) * 2002-12-20 2004-07-15 Applera Corporation Genetic polymorphisms associated with stenosis, methods of detection and uses thereof
WO2004081186A2 (en) * 2003-03-10 2004-09-23 Applera Corporation Single nucleotide polymorphisms associated with stenosis, methods of detection and uses thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001514522A (ja) * 1997-03-10 2001-09-11 インターロイキン・ジェネティクス・インコーポレーテッド 冠状動脈疾患の予測
JP2003500069A (ja) * 1999-05-24 2003-01-07 インタールーキン ジェネティックス インク 再狭窄の診断及び治療薬
JP2003500071A (ja) * 1999-05-26 2003-01-07 インターロイキン・ジェネティクス・インコーポレーテッド 心血管障害のための診断及び治療
WO2002036770A2 (fr) * 2000-10-31 2002-05-10 Aventis Pharma S.A. Sequences polymorphes du gene humain abca1, leurs utilisations, les methodes et kits de detection
JP2002360275A (ja) * 2000-12-22 2002-12-17 Pfizer Prod Inc 心臓血管疾患に関連する方法、組成物およびキット
WO2003072813A2 (en) * 2002-02-27 2003-09-04 Bayer Healthcare Ag Single nucleotide polymorphisms predicting adverse drug reactions and medication efficacy

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018513141A (ja) * 2015-04-20 2018-05-24 コンセジョ スペリオール デ インベスティガショネス シエンティフィカス ヒトカドヘリン−17、ヒトカドヘリン−5、ヒトカドヘリン−6およびヒトカドヘリン−20のrgdモチーフに特異的に結合する薬剤

Also Published As

Publication number Publication date
CA2566257A1 (en) 2005-11-24
WO2005110039A2 (en) 2005-11-24
US20050287559A1 (en) 2005-12-29
WO2005110039A3 (en) 2007-01-04
EP1753875A2 (en) 2007-02-21

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