JP2009518372A - 線維症用の新規造影剤 - Google Patents

線維症用の新規造影剤 Download PDF

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Publication number
JP2009518372A
JP2009518372A JP2008543898A JP2008543898A JP2009518372A JP 2009518372 A JP2009518372 A JP 2009518372A JP 2008543898 A JP2008543898 A JP 2008543898A JP 2008543898 A JP2008543898 A JP 2008543898A JP 2009518372 A JP2009518372 A JP 2009518372A
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JP
Japan
Prior art keywords
contrast agent
group
contrast
vector
agent according
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Pending
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JP2008543898A
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English (en)
Japanese (ja)
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JP2009518372A5 (enExample
Inventor
チェティッビ，サラ
ニュートン，ベン
ギルバート，ベネディクト
トーレスハーグ，ヘルジ
ソルバッケン，マグネ
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GE Healthcare Ltd
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GE Healthcare Ltd
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Application filed by GE Healthcare Ltd filed Critical GE Healthcare Ltd
Publication of JP2009518372A publication Critical patent/JP2009518372A/ja
Publication of JP2009518372A5 publication Critical patent/JP2009518372A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
JP2008543898A 2005-12-08 2006-12-07 線維症用の新規造影剤 Pending JP2009518372A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0524987.5A GB0524987D0 (en) 2005-12-08 2005-12-08 Novel imaging agents for fibrosis
PCT/GB2006/004575 WO2007066115A2 (en) 2005-12-08 2006-12-07 Novel imaging agents for fibrosis

Publications (2)

Publication Number Publication Date
JP2009518372A true JP2009518372A (ja) 2009-05-07
JP2009518372A5 JP2009518372A5 (enExample) 2012-10-18

Family

ID=35735731

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008543898A Pending JP2009518372A (ja) 2005-12-08 2006-12-07 線維症用の新規造影剤

Country Status (6)

Country Link
US (1) US20080279765A1 (enExample)
EP (2) EP2305316A3 (enExample)
JP (1) JP2009518372A (enExample)
CN (1) CN101325978A (enExample)
GB (1) GB0524987D0 (enExample)
WO (1) WO2007066115A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8574623B2 (en) 2004-12-22 2013-11-05 Nitto Denko Corporation Therapeutic agent for pulmonary fibrosis
JP2015526402A (ja) * 2012-06-29 2015-09-10 ジーイー・ヘルスケア・リミテッド 線維症のイメージング

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009221164A (ja) * 2008-03-17 2009-10-01 Nitto Denko Corp 肺線維症処置剤
US9572886B2 (en) 2005-12-22 2017-02-21 Nitto Denko Corporation Agent for treating myelofibrosis
GB0722650D0 (en) * 2007-11-19 2007-12-27 Ge Healthcare Ltd Novel imaging method
CA2975841C (en) * 2008-04-30 2021-05-25 Siemens Medical Solutions Usa, Inc. Substrate based pet imaging agents
KR20160095209A (ko) * 2008-09-12 2016-08-10 닛토덴코 가부시키가이샤 섬유증 질환의 조영제
CN101738468B (zh) * 2008-11-24 2013-03-27 中国医学科学院阜外心血管病医院 胰岛素样生长因子ⅱ受体在检测心力衰竭中的应用及试剂盒
US8154285B1 (en) 2009-05-29 2012-04-10 The Invention Science Fund I, Llc Non-external static magnetic field imaging systems, devices, methods, and compositions
US8063636B2 (en) * 2009-05-29 2011-11-22 The Invention Science Fund I, Llc Systems, devices, methods, and compositions including targeted ferromagnetic structures
US8058872B2 (en) 2009-05-29 2011-11-15 The Invention Science Fund I, Llc Systems, devices, methods, and compositions including functionalized ferromagnetic structures
US8106655B2 (en) * 2009-05-29 2012-01-31 The Invention Science Fund I, Llc Multiplex imaging systems, devices, methods, and compositions including ferromagnetic structures
US20100303733A1 (en) * 2009-05-29 2010-12-02 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems, devices, methods, and compositions including ferromagnetic structures
JP5950428B2 (ja) 2010-08-05 2016-07-13 日東電工株式会社 線維化組織から正常組織を再生するための組成物
JP5517306B2 (ja) * 2011-01-26 2014-06-11 日東電工株式会社 肺線維症処置剤
US8580922B2 (en) 2011-03-04 2013-11-12 Shire Human Genetic Therapies, Inc. Peptide linkers for polypeptide compositions and methods for using same
WO2012122042A2 (en) * 2011-03-04 2012-09-13 Shire Human Genetic Therapies, Inc. Peptide linkers for polypeptide compositions and methods for using same
JP6340162B2 (ja) 2012-12-20 2018-06-06 日東電工株式会社 アポトーシス誘導剤
ES2821966T3 (es) 2014-04-02 2021-04-28 Nitto Denko Corp Molécula de direccionamiento derivada de RBP y utilización de la misma
RU2676680C2 (ru) 2014-04-07 2019-01-10 Нитто Денко Корпорейшн Новые гидротропы на основе полимера для доставки гидрофобного лекарственного средства
CN105343900B (zh) * 2015-09-16 2019-04-02 中国海洋大学 褐藻多糖为载体的淋巴靶向核磁造影剂及制备方法和应用
CN105148291A (zh) * 2015-09-16 2015-12-16 中国海洋大学 多聚糖醛酸为载体的活体染色造影剂及制备方法和应用

Citations (4)

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JPH02502014A (ja) * 1987-09-25 1990-07-05 ジェネンテック，インコーポレイティド フィブリン結合性蛋白質を用いる血餅の診断方法
JP2002532384A (ja) * 1998-10-08 2002-10-02 ステイヒテイング・ボール・デ・テヒニシエ・ベテンシヤツペン 星状細胞のためのペプチドを基剤としたキャリヤーデバイス
JP2004535791A (ja) * 2001-04-30 2004-12-02 シンビオンティクス， インコーポレイテッド 治療的タンパク質の亜細胞標的化
WO2005049095A2 (en) * 2003-11-24 2005-06-02 Amersham Health As Contrast agent imaging angiotensin ii receptors

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US4885363A (en) 1987-04-24 1989-12-05 E. R. Squibb & Sons, Inc. 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
ATE120374T1 (de) 1989-07-20 1995-04-15 Sandoz Ag Markierte polypeptidderivate.
DK129293D0 (da) 1993-11-16 1993-11-16 Carlsberg Lab Carbonhydratholdige forbindelser, der kan binde sig til carbonhydratbindende receptorer
US6908903B1 (en) * 1994-12-07 2005-06-21 Aletheon Pharmaceuticals, Inc. Cluster clearing agents
GB0115927D0 (en) 2001-06-29 2001-08-22 Nycomed Amersham Plc Solid-phase nucleophilic fluorination
GB0115929D0 (en) 2001-06-29 2001-08-22 Nycomed Amersham Plc Solid-phase electrophilic fluorination
GB0206750D0 (en) 2002-03-22 2002-05-01 Amersham Plc Radiofluorination methods
JP4874090B2 (ja) * 2003-01-31 2012-02-08 イミューノメディクス、インコーポレイテッド 治療薬および診断薬を投与するための方法および組成物
EP1495769B1 (en) * 2003-07-11 2008-02-27 LBR Medbiotech B.V. Mannose-6-phosphate receptor mediated gene transfer into muscle cells
US20060148740A1 (en) * 2005-01-05 2006-07-06 Prosensa B.V. Mannose-6-phosphate receptor mediated gene transfer into muscle cells

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02502014A (ja) * 1987-09-25 1990-07-05 ジェネンテック，インコーポレイティド フィブリン結合性蛋白質を用いる血餅の診断方法
JP2002532384A (ja) * 1998-10-08 2002-10-02 ステイヒテイング・ボール・デ・テヒニシエ・ベテンシヤツペン 星状細胞のためのペプチドを基剤としたキャリヤーデバイス
JP2004535791A (ja) * 2001-04-30 2004-12-02 シンビオンティクス， インコーポレイテッド 治療的タンパク質の亜細胞標的化
WO2005049095A2 (en) * 2003-11-24 2005-06-02 Amersham Health As Contrast agent imaging angiotensin ii receptors

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CSNC200800784017; 小泉 潔: '腫瘍シンチグラフィｕｐｄａｔｅ' 画像診断 Ｖｏｌ．１８ Ｎｏ．１２, 1998, １３０８-１３１８, 株式会社秀潤社 *
CSNC200901714021; 横山 邦彦: '腫瘍核医学の最新動向' 月刊新医療 第２４巻第３号, 1997, ７９-８２, 株式会社エム・イー振興協会 *
JPN6012010320; Ｍｏｌｅｃｕｌａｒ　ａｎｄ　Ｇｅｎｅｒａｌ　Ｇｅｎｅｔｉｃｓ ｖｏｌ．２６４, 2001, ｐ．５７８-５８７ *
JPN6012010321; Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｎｕｃｌｅａｒ　Ｍｅｄｉｃｉｎｅ ｖｏｌ．３４，　ｎｏ．１０, 1993, ｐ．１７２８-１７３８ *
JPN6012010322; Ｂｉｏｃｈｅｍｉｃａｌ　ａｎｄ　Ｂｉｏｐｈｙｓｉｃａｌ　Ｒｅｓｅａｒｃｈ　Ｃｏｍｍｕｎｉｃａｔｉｏｎｓ ｖｏｌ．１５２，　ｎｏ．３, 1988, ｐ．１２４８-１２５４ *
JPN6012062539; 小泉 潔: '腫瘍シンチグラフィｕｐｄａｔｅ' 画像診断 Ｖｏｌ．１８ Ｎｏ．１２, 1998, １３０８-１３１８, 株式会社秀潤社 *
JPN6012062542; 横山 邦彦: '腫瘍核医学の最新動向' 月刊新医療 第２４巻第３号, 1997, ７９-８２, 株式会社エム・イー振興協会 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8574623B2 (en) 2004-12-22 2013-11-05 Nitto Denko Corporation Therapeutic agent for pulmonary fibrosis
JP2015526402A (ja) * 2012-06-29 2015-09-10 ジーイー・ヘルスケア・リミテッド 線維症のイメージング

Also Published As

Publication number Publication date
WO2007066115A3 (en) 2007-11-29
EP1957114A2 (en) 2008-08-20
WO2007066115B1 (en) 2008-01-31
EP2305316A2 (en) 2011-04-06
EP2305316A3 (en) 2011-06-08
GB0524987D0 (en) 2006-01-18
US20080279765A1 (en) 2008-11-13
CN101325978A (zh) 2008-12-17
WO2007066115A2 (en) 2007-06-14

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