JP2009511589A - アリール−シクロプロピル誘導体のアスパルチルプロテアーゼ阻害剤を使用してアミロイドーシスを治療する方法 - Google Patents

アリール−シクロプロピル誘導体のアスパルチルプロテアーゼ阻害剤を使用してアミロイドーシスを治療する方法 Download PDF

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JP2009511589A
JP2009511589A JP2008535650A JP2008535650A JP2009511589A JP 2009511589 A JP2009511589 A JP 2009511589A JP 2008535650 A JP2008535650 A JP 2008535650A JP 2008535650 A JP2008535650 A JP 2008535650A JP 2009511589 A JP2009511589 A JP 2009511589A
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difluorophenyl
acetamide
cyclopropylamino
phenyl
hydroxybutan
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JP2009511589A5 (enExample
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ホム，ロイ
トス，ガーゲリー
プロブスト，ギャリー
ボウワーズ，シミオン
トゥルオング，アンー
タング，ジェイ・エス
ネイツ，アール・ジェフリー
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エラン ファーマシューティカルズ，インコーポレイテッド
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Publication of JP2009511589A5 publication Critical patent/JP2009511589A5/ja
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    • C07C233/36—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
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