JP2009504576A5 - - Google Patents
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- Publication number
- JP2009504576A5 JP2009504576A5 JP2008525352A JP2008525352A JP2009504576A5 JP 2009504576 A5 JP2009504576 A5 JP 2009504576A5 JP 2008525352 A JP2008525352 A JP 2008525352A JP 2008525352 A JP2008525352 A JP 2008525352A JP 2009504576 A5 JP2009504576 A5 JP 2009504576A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- glutamine
- source
- use according
- glutamine source
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 16
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 claims 12
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 claims 10
- 108010016626 Dipeptides Proteins 0.000 claims 4
- 229930182816 L-glutamine Natural products 0.000 claims 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims 4
- 206010060932 Postoperative adhesion Diseases 0.000 claims 3
- 230000015572 biosynthetic process Effects 0.000 claims 3
- 238000007912 intraperitoneal administration Methods 0.000 claims 3
- HJCMDXDYPOUFDY-WHFBIAKZSA-N Ala-Gln Chemical group C[C@H](N)C(=O)N[C@H](C(O)=O)CCC(N)=O HJCMDXDYPOUFDY-WHFBIAKZSA-N 0.000 claims 2
- 125000003338 L-glutaminyl group Chemical group O=C([*])[C@](N([H])[H])([H])C([H])([H])C([H])([H])C(=O)N([H])[H] 0.000 claims 2
- 108010044940 alanylglutamine Proteins 0.000 claims 2
- 229960002648 alanylglutamine Drugs 0.000 claims 2
- 238000001356 surgical procedure Methods 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 210000003200 peritoneal cavity Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70717305P | 2005-08-11 | 2005-08-11 | |
| US60/707,173 | 2005-08-11 | ||
| PCT/CA2006/001319 WO2007016791A1 (en) | 2005-08-11 | 2006-08-11 | Reducing post-operative adhesion formation with intraperitoneal glutamine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009504576A JP2009504576A (ja) | 2009-02-05 |
| JP2009504576A5 true JP2009504576A5 (https=) | 2009-09-24 |
| JP5194207B2 JP5194207B2 (ja) | 2013-05-08 |
Family
ID=37727066
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008525352A Active JP5194207B2 (ja) | 2005-08-11 | 2006-08-11 | 腹腔内グルタミンによる術後癒着形成の減少 |
Country Status (14)
| Country | Link |
|---|---|
| US (5) | US20100260819A1 (https=) |
| EP (1) | EP1940439B1 (https=) |
| JP (1) | JP5194207B2 (https=) |
| AT (1) | ATE485829T1 (https=) |
| AU (1) | AU2006279218B2 (https=) |
| CA (1) | CA2618600C (https=) |
| CY (1) | CY1112051T1 (https=) |
| DE (1) | DE602006017864D1 (https=) |
| DK (1) | DK1940439T3 (https=) |
| ES (1) | ES2355159T3 (https=) |
| PL (1) | PL1940439T3 (https=) |
| PT (1) | PT1940439E (https=) |
| SI (1) | SI1940439T1 (https=) |
| WO (1) | WO2007016791A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1940439E (pt) | 2005-08-11 | 2010-12-17 | Univ Saskatchewan | Redução da formação de aderências pós-operatórias com glutamina intraperitoneal |
| CA2578647A1 (en) * | 2007-02-15 | 2008-08-15 | University Of Saskatchewan | Reducing post-operative adhesion formation with intraperitoneal glutamine |
| JP5433424B2 (ja) | 2007-03-02 | 2014-03-05 | シュトプロテック ゲーエムベーハー | グルタミン残基を含む炭水化物系腹膜透析液 |
| US20100082113A1 (en) * | 2008-04-29 | 2010-04-01 | Peter Gingras | Tissue repair implant |
| RU2578426C2 (ru) * | 2010-06-28 | 2016-03-27 | Эдитерапьютикс, Инк. | Лечение келоидов |
| WO2014027545A1 (ja) | 2012-08-16 | 2014-02-20 | ニプロ株式会社 | 癒着防止材 |
| WO2017190148A1 (en) * | 2016-04-29 | 2017-11-02 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for the prevention and treatment of surgical adhesions |
| EP3471791B1 (en) | 2016-06-15 | 2020-08-05 | Tubitak | Multifunctional hernia patch |
| US10500318B1 (en) * | 2018-07-03 | 2019-12-10 | Temple Therapeutics BV | Dosing regimens for treating hypoxia-associated tissue damage |
| WO2022234489A1 (en) | 2021-05-07 | 2022-11-10 | Temple Therapeutics BV | Methods of treating fibrosis and hypoxia-associated damage to peripheral nerves |
| WO2025163204A1 (en) | 2024-02-01 | 2025-08-07 | Temple Therapeutics BV | Glutamine source for use in methods and compositions for reducing or preventing synovial joint adhesions or fibrosis |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2026881A1 (en) * | 1989-02-08 | 1990-08-09 | Masao Tanihara | Peptide and adsorbent thereof immobilized on carrier |
| US5248697A (en) | 1990-09-20 | 1993-09-28 | Brigham And Women's Hospital | Enhancement of glutathione levels with glutamine |
| CA2114290C (en) * | 1993-01-27 | 2006-01-10 | Nagabushanam Totakura | Post-surgical anti-adhesion device |
| US5425740A (en) * | 1994-05-17 | 1995-06-20 | Hutchinson, Jr.; William B. | Endoscopic hernia repair clip and method |
| US6965014B1 (en) * | 1996-01-16 | 2005-11-15 | Baxter International Inc. | Fibrin material and method for producing and using the same |
| US6280745B1 (en) * | 1997-12-23 | 2001-08-28 | Alliance Pharmaceutical Corp. | Methods and compositions for the delivery of pharmaceutical agents and/or the prevention of adhesions |
| US5693671A (en) * | 1996-05-01 | 1997-12-02 | Harbor-Ucla Research And Education Institute | L-glutamine therapy for sickle cell diseases and thalassemia |
| GB9609993D0 (en) | 1996-05-14 | 1996-07-17 | Norbrook Lab Ltd | Oral rehydration product |
| US6797729B1 (en) * | 1996-06-28 | 2004-09-28 | Baxter International Inc. | Therapeutic glutamine and N-actyl-cysteine composition |
| US6063061A (en) * | 1996-08-27 | 2000-05-16 | Fusion Medical Technologies, Inc. | Fragmented polymeric compositions and methods for their use |
| US6495579B1 (en) * | 1996-12-02 | 2002-12-17 | Angiotech Pharmaceuticals, Inc. | Method for treating multiple sclerosis |
| WO1999009982A1 (en) * | 1997-08-25 | 1999-03-04 | Harold Brem | Prevention of adhesions and excessive scar formation using angiogenesis inhibitors |
| CA2330939A1 (en) * | 1998-06-16 | 1999-12-23 | Biogen, Inc. | Variant type ii tgf-beta receptor fusion proteins and methods |
| JP2002521423A (ja) | 1998-07-31 | 2002-07-16 | コリア インスティチュート オブ サイエンス アンド テクノロージ | 遺伝子又は薬物運搬体としての脂質エマルジョン及び固形脂質微粒子 |
| US6613070B2 (en) * | 1998-08-04 | 2003-09-02 | Baxter International Inc. | System and method for sealing vascular penetrations with hemostatic gels |
| US20030007951A1 (en) | 2000-08-23 | 2003-01-09 | Richard Franklin | Treatment of trauma |
| CN100382796C (zh) * | 2002-10-08 | 2008-04-23 | 艾博特公司 | 用于提供谷氨酰胺的方法和组合物 |
| CA2538680A1 (en) | 2003-09-26 | 2005-04-07 | Bristol-Myers Squibb Company | Arginyl-glutamine dipeptide for treatment of pathological vascular proliferation |
| PT1940439E (pt) * | 2005-08-11 | 2010-12-17 | Univ Saskatchewan | Redução da formação de aderências pós-operatórias com glutamina intraperitoneal |
-
2006
- 2006-08-11 PT PT06775098T patent/PT1940439E/pt unknown
- 2006-08-11 AT AT06775098T patent/ATE485829T1/de active
- 2006-08-11 PL PL06775098T patent/PL1940439T3/pl unknown
- 2006-08-11 WO PCT/CA2006/001319 patent/WO2007016791A1/en not_active Ceased
- 2006-08-11 EP EP20060775098 patent/EP1940439B1/en active Active
- 2006-08-11 DK DK06775098T patent/DK1940439T3/da active
- 2006-08-11 CA CA2618600A patent/CA2618600C/en active Active
- 2006-08-11 SI SI200630887T patent/SI1940439T1/sl unknown
- 2006-08-11 DE DE200660017864 patent/DE602006017864D1/de active Active
- 2006-08-11 JP JP2008525352A patent/JP5194207B2/ja active Active
- 2006-08-11 AU AU2006279218A patent/AU2006279218B2/en active Active
- 2006-08-11 ES ES06775098T patent/ES2355159T3/es active Active
- 2006-08-11 US US12/063,423 patent/US20100260819A1/en not_active Abandoned
-
2011
- 2011-01-04 CY CY20111100013T patent/CY1112051T1/el unknown
-
2013
- 2013-02-27 US US13/779,362 patent/US9011883B2/en active Active
-
2015
- 2015-03-17 US US14/660,382 patent/US20150250928A1/en not_active Abandoned
-
2017
- 2017-04-05 US US15/480,148 patent/US20170203013A1/en not_active Abandoned
-
2018
- 2018-11-05 US US16/180,637 patent/US10799622B2/en active Active
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