JP2009501533A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009501533A5 JP2009501533A5 JP2008521742A JP2008521742A JP2009501533A5 JP 2009501533 A5 JP2009501533 A5 JP 2009501533A5 JP 2008521742 A JP2008521742 A JP 2008521742A JP 2008521742 A JP2008521742 A JP 2008521742A JP 2009501533 A5 JP2009501533 A5 JP 2009501533A5
- Authority
- JP
- Japan
- Prior art keywords
- oocyte
- bmp
- activity
- medium
- modulating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000000287 oocyte Anatomy 0.000 claims 65
- 238000000034 method Methods 0.000 claims 37
- 230000000694 effects Effects 0.000 claims 31
- 239000002609 medium Substances 0.000 claims 29
- 230000019491 signal transduction Effects 0.000 claims 22
- 108010049974 Bone Morphogenetic Protein 6 Proteins 0.000 claims 20
- 102100022525 Bone morphogenetic protein 6 Human genes 0.000 claims 20
- 230000001419 dependent effect Effects 0.000 claims 20
- 102000003928 Bone morphogenetic protein 15 Human genes 0.000 claims 19
- 108090000349 Bone morphogenetic protein 15 Proteins 0.000 claims 19
- 210000001771 cumulus cell Anatomy 0.000 claims 18
- 210000001161 mammalian embryo Anatomy 0.000 claims 17
- 102000004858 Growth differentiation factor-9 Human genes 0.000 claims 15
- 108090001086 Growth differentiation factor-9 Proteins 0.000 claims 15
- 210000002503 granulosa cell Anatomy 0.000 claims 12
- 239000003795 chemical substances by application Substances 0.000 claims 10
- 230000035800 maturation Effects 0.000 claims 10
- 230000001105 regulatory effect Effects 0.000 claims 7
- 230000006907 apoptotic process Effects 0.000 claims 6
- 210000002257 embryonic structure Anatomy 0.000 claims 4
- 230000003325 follicular Effects 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 239000001963 growth medium Substances 0.000 claims 3
- 230000001737 promoting effect Effects 0.000 claims 3
- 102000012673 Follicle Stimulating Hormone Human genes 0.000 claims 2
- 108010079345 Follicle Stimulating Hormone Proteins 0.000 claims 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
- 239000013066 combination product Substances 0.000 claims 2
- 229940127555 combination product Drugs 0.000 claims 2
- 239000003636 conditioned culture medium Substances 0.000 claims 2
- 230000013020 embryo development Effects 0.000 claims 2
- 230000004720 fertilization Effects 0.000 claims 2
- 229940028334 follicle stimulating hormone Drugs 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 210000002394 ovarian follicle Anatomy 0.000 claims 2
- 210000001672 ovary Anatomy 0.000 claims 2
- 230000028327 secretion Effects 0.000 claims 2
- 210000001519 tissue Anatomy 0.000 claims 2
- 102000009027 Albumins Human genes 0.000 claims 1
- 108010088751 Albumins Proteins 0.000 claims 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 1
- 230000002424 anti-apoptotic effect Effects 0.000 claims 1
- 230000018109 developmental process Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 102000013361 fetuin Human genes 0.000 claims 1
- 108060002885 fetuin Proteins 0.000 claims 1
- 210000001733 follicular fluid Anatomy 0.000 claims 1
- -1 follicular fluid Proteins 0.000 claims 1
- 230000008014 freezing Effects 0.000 claims 1
- 238000007710 freezing Methods 0.000 claims 1
- 239000008103 glucose Substances 0.000 claims 1
- 239000003102 growth factor Substances 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 238000010257 thawing Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2005903782A AU2005903782A0 (en) | 2005-07-18 | Modulation of granulosa cell apoptosis | |
| PCT/AU2006/001002 WO2007009166A1 (en) | 2005-07-18 | 2006-07-18 | Modulation of granulosa cell apoptosis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013141544A Division JP5841973B2 (ja) | 2005-07-18 | 2013-07-05 | 顆粒膜細胞アポトーシスの調節 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009501533A JP2009501533A (ja) | 2009-01-22 |
| JP2009501533A5 true JP2009501533A5 (https=) | 2009-09-03 |
Family
ID=37668339
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008521742A Pending JP2009501533A (ja) | 2005-07-18 | 2006-07-18 | 顆粒膜細胞アポトーシスの調節 |
| JP2013141544A Expired - Fee Related JP5841973B2 (ja) | 2005-07-18 | 2013-07-05 | 顆粒膜細胞アポトーシスの調節 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013141544A Expired - Fee Related JP5841973B2 (ja) | 2005-07-18 | 2013-07-05 | 顆粒膜細胞アポトーシスの調節 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8530235B2 (https=) |
| EP (2) | EP2228070B1 (https=) |
| JP (2) | JP2009501533A (https=) |
| KR (1) | KR101502110B1 (https=) |
| CN (1) | CN101272804A (https=) |
| CA (1) | CA2615006A1 (https=) |
| DK (1) | DK2228070T3 (https=) |
| WO (1) | WO2007009166A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014018404A1 (en) * | 2012-07-21 | 2014-01-30 | Baylor College Of Medicine | Gdf9:bmp15 heterodimers for enhancing fertility |
| US20160237402A1 (en) * | 2013-10-07 | 2016-08-18 | Northeastern University | Methods and Compositions for Ex Vivo Generation of Developmentally Competent Eggs from Germ Line Cells Using Autologous Cell Systems |
| EP3122366A4 (en) | 2014-03-27 | 2017-11-15 | Jonathan Lee Tilly | Methods for growth and maturation of ovarian follicles |
| EP3577457A4 (en) * | 2017-02-01 | 2021-01-20 | Robert Bruce Gilchrist | GROWTH FACTORS SECRETED BY GAMETES |
| CN112601756A (zh) | 2018-05-09 | 2021-04-02 | 莫拿什大学 | 用于增强生育力的剂和方法 |
| CN116814685B (zh) * | 2023-06-05 | 2025-05-06 | 华南农业大学 | Zfp42基因在猪卵巢颗粒细胞中的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0678101A4 (en) | 1993-01-12 | 1997-07-16 | Univ Johns Hopkins Med | FACTOR-9 OF GROWTH AND DIFFERENTIATION. |
| US6030617A (en) * | 1993-01-12 | 2000-02-29 | The Johns Hopkins University School Of Medicine | Use of growth differentiation factor-9 (GDF-9) to inhibit oocyte maturation |
| AU753793B2 (en) * | 1998-04-01 | 2002-10-31 | Baylor College Of Medicine | Assay for growth differentiation factor 9 |
| DE69907725T2 (de) * | 1998-12-01 | 2004-03-18 | Akzo Nobel N.V. | Verbesserung der follikelgenese |
| NZ502796A (en) * | 2000-06-15 | 2003-02-28 | Agres Ltd | Nucleotide and amino acid sequences of oocyte factors related to GDF-9B or GDF-9 |
| FR2812004B1 (fr) * | 2000-07-24 | 2002-12-27 | Ccd Lab | Milieux de culture pour fecondation in vitro, ou pour la culture de follicules, cellules germinales males ou embryons |
| WO2005097978A1 (en) * | 2004-04-06 | 2005-10-20 | Adelaide Research & Innovation Pty Ltd | Modulation of granulosa cell proliferation and differentiation |
| JP2008521891A (ja) * | 2004-12-02 | 2008-06-26 | アグリサーチ・リミテッド | 排卵の調節 |
-
2006
- 2006-07-18 WO PCT/AU2006/001002 patent/WO2007009166A1/en not_active Ceased
- 2006-07-18 KR KR1020087003867A patent/KR101502110B1/ko not_active Expired - Fee Related
- 2006-07-18 JP JP2008521742A patent/JP2009501533A/ja active Pending
- 2006-07-18 CA CA002615006A patent/CA2615006A1/en not_active Abandoned
- 2006-07-18 EP EP10004342.1A patent/EP2228070B1/en not_active Not-in-force
- 2006-07-18 CN CNA2006800343274A patent/CN101272804A/zh active Pending
- 2006-07-18 US US11/988,949 patent/US8530235B2/en not_active Expired - Fee Related
- 2006-07-18 EP EP06760864A patent/EP1909820A4/en not_active Withdrawn
- 2006-07-18 DK DK10004342.1T patent/DK2228070T3/da active
-
2013
- 2013-07-05 JP JP2013141544A patent/JP5841973B2/ja not_active Expired - Fee Related
- 2013-08-15 US US13/968,359 patent/US20140073052A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Ford et al. | Advances in human primordial follicle activation and premature ovarian insufficiency | |
| Vadnais et al. | Characterization of capacitation, cryoinjury, and the role of seminal plasma in porcine sperm | |
| Nagy et al. | Clinical evaluation of the efficiency of an oocyte donation program using egg cryo-banking | |
| Shapiro et al. | Freeze-all can be a superior therapy to another fresh cycle in patients with prior fresh blastocyst implantation failure | |
| Navarrete et al. | Transient exposure to calcium ionophore enables in vitro fertilization in sterile mouse models | |
| Ku et al. | Comparison of the clinical outcomes between fresh blastocyst and vitrified-thawed blastocyst transfer | |
| Vadnais et al. | Effects of seminal plasma on cooling‐induced capacitative changes in boar sperm | |
| Benirschke et al. | Placental types | |
| Martino et al. | Oocyte mitochondrial bioenergy potential and oxidative stress: within-/between-subject, in vivo versus in vitro maturation, and age-related variations in a sheep model | |
| Rienzi et al. | Developmental potential of fully intact and partially damaged cryopreserved embryos after laser-assisted removal of necrotic blastomeres and post-thaw culture selection | |
| Meirelles et al. | Delivery of cloned offspring: experience in Zebu cattle (Bos indicus) | |
| Vladimirov et al. | Theory about the embryo cryo‐treatment | |
| Leroy et al. | Maternal metabolic health and fertility: we should not only care about but also for the oocyte! | |
| JP2009501533A5 (https=) | ||
| Kovačič et al. | Importance of blastocyst morphology in selection for transfer | |
| Iwata et al. | Effects of modification of in vitro fertilization techniques on the sex ratio of the resultant bovine embryos | |
| Kim et al. | Amwaprin is a sperm-binding protein that inhibits sperm motility and enhances sperm viability in honeybees | |
| Yu et al. | The effects of type I collagenase on the degelification of chimpanzee (Pan troglodytes) semen plug and sperm quality | |
| EP4583706A1 (en) | Method for the preservation of functional gametes | |
| De et al. | In vitro development of goat (Capra hircus) embryos following cysteamine supplementation of the in vitro maturation and in vitro culture media | |
| Gradl et al. | Supernatant of traumatized muscle induces inflammation and pain, but not microcirculatory perfusion failure and apoptotic cell death | |
| Demyda-Peyrás et al. | In vitro induction of the acrosome reaction in spermatozoa from endangered Spanish bulls: Effect of breed, culture media and incubation time | |
| Liu et al. | Effect of vitrification of mouse oocyte on the behavior of adult offspring | |
| Klein | Development of a novel medium for storing bull spermatozoa at room temperature | |
| Pribenszky et al. | Stress for stress tolerance: improving cell survival by sublethal stress treatment of eggs before vitrification–pilot study |